CN101842381A - 作为微小rna模拟物或抑制剂的不对称rna双链体的组合物 - Google Patents

作为微小rna模拟物或抑制剂的不对称rna双链体的组合物 Download PDF

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CN101842381A
CN101842381A CN200880113323A CN200880113323A CN101842381A CN 101842381 A CN101842381 A CN 101842381A CN 200880113323 A CN200880113323 A CN 200880113323A CN 200880113323 A CN200880113323 A CN 200880113323A CN 101842381 A CN101842381 A CN 101842381A
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chain
stand
nucleotide
inhibitor
mirna
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C·J·李
H·罗格夫
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1Globe Biomedical Co Ltd
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Boston Biomedical Inc
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CN200880113323A 2007-08-27 2008-08-27 作为微小rna模拟物或抑制剂的不对称rna双链体的组合物 Pending CN101842381A (zh)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US96825707P 2007-08-27 2007-08-27
US60/968,257 2007-08-27
US2975308P 2008-02-19 2008-02-19
US61/029,753 2008-02-19
US3895408P 2008-03-24 2008-03-24
US61/038,954 2008-03-24
PCT/US2008/074531 WO2009029690A1 (en) 2007-08-27 2008-08-27 Composition of asymmetric rna duplex as microrna mimetic or inhibitor

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CN101842381A true CN101842381A (zh) 2010-09-22

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CN201510250692.XA Active CN105018492B (zh) 2007-08-27 2008-08-27 不对称干扰rna的组合物及其用途
CN200880113323A Pending CN101842381A (zh) 2007-08-27 2008-08-27 作为微小rna模拟物或抑制剂的不对称rna双链体的组合物
CN200880113236.9A Active CN101835789B (zh) 2007-08-27 2008-08-27 不对称干扰rna的组合物及其用途

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EP (4) EP2193140B1 (enExample)
JP (7) JP2010537640A (enExample)
CN (3) CN105018492B (enExample)
CA (2) CA2735167A1 (enExample)
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CN107109415A (zh) * 2014-12-27 2017-08-29 株式会社博纳克 控制基因表达的天然型miRNA及其用途
CN107207556A (zh) * 2014-11-14 2017-09-26 沃雅戈治疗公司 调节性多核苷酸
CN107532181A (zh) * 2015-03-16 2018-01-02 米拉根医疗股份有限公司 Mirna模拟物和它们在治疗感觉病患中的用途
WO2018014848A1 (zh) * 2016-07-19 2018-01-25 上海市东方医院 一种小rna抑制剂
CN118460650A (zh) * 2024-07-10 2024-08-09 凯莱英医药集团（天津）股份有限公司 一种Nedosiran的制备方法
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CN101979558B (zh) * 2010-10-28 2015-09-02 百奥迈科生物技术有限公司 一种靶向乙型肝炎病毒基因的siRNA分子及其应用
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JP6137484B2 (ja) * 2011-11-02 2017-05-31 公立大学法人大阪市立大学 遺伝子発現抑制用二本鎖核酸分子
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