|
CN101631454A
(zh)
|
2006-12-08 |
2010-01-20 |
衣阿华州立大学研究基金公司 |
参与硝酸盐吸收和代谢的植物基因
|
|
EP2193140B1
(en)
*
|
2007-08-27 |
2016-11-02 |
1Globe Health Institute LLC |
Compositions of asymmetric interfering rna and uses thereof
|
|
US8097712B2
(en)
|
2007-11-07 |
2012-01-17 |
Beelogics Inc. |
Compositions for conferring tolerance to viral disease in social insects, and the use thereof
|
|
KR100949791B1
(ko)
*
|
2007-12-18 |
2010-03-30 |
이동기 |
오프-타겟 효과를 최소화하고 RNAi 기구를 포화시키지않는 신규한 siRNA 구조 및 그 용도
|
|
EP2340309A2
(en)
|
2008-09-22 |
2011-07-06 |
Rxi Pharmaceuticals Corporation |
Neutral nanotransporters
|
|
CN102224254A
(zh)
|
2008-09-23 |
2011-10-19 |
哈佛大学校长及研究员协会 |
Sirt4及其用途
|
|
EP2352744B1
(en)
*
|
2008-10-15 |
2016-09-21 |
Somagenics, Inc. |
Short hairpin rnas for inhibition of gene expression
|
|
US9493774B2
(en)
|
2009-01-05 |
2016-11-15 |
Rxi Pharmaceuticals Corporation |
Inhibition of PCSK9 through RNAi
|
|
WO2010090762A1
(en)
|
2009-02-04 |
2010-08-12 |
Rxi Pharmaceuticals Corporation |
Rna duplexes with single stranded phosphorothioate nucleotide regions for additional functionality
|
|
ES2628144T3
(es)
*
|
2009-04-03 |
2017-08-01 |
Dicerna Pharmaceuticals, Inc. |
Métodos y composiciones para la inhibición específica de KRAS por RNA bicatenario asimétrico
|
|
EP2756845B1
(en)
*
|
2009-04-03 |
2017-03-15 |
Dicerna Pharmaceuticals, Inc. |
Methods and compositions for the specific inhibition of KRAS by asymmetric double-stranded RNA
|
|
WO2010141933A1
(en)
*
|
2009-06-05 |
2010-12-09 |
Dicerna Pharmaceuticals, Inc. |
Specific inhibition of gene expression by nucleic acid containing a dicer substrate
|
|
US8871730B2
(en)
|
2009-07-13 |
2014-10-28 |
Somagenics Inc. |
Chemical modification of short small hairpin RNAs for inhibition of gene expression
|
|
US8796238B2
(en)
|
2009-09-17 |
2014-08-05 |
Sigma-Aldrich Co. Llc |
Short RNA mimetics
|
|
KR20120082906A
(ko)
|
2009-09-30 |
2012-07-24 |
프레지던트 앤드 펠로우즈 오브 하바드 칼리지 |
자가포식현상-향상 유전자 생성물의 조절을 통한 자가포식현상의 조절 방법
|
|
US20150025122A1
(en)
|
2009-10-12 |
2015-01-22 |
Larry J. Smith |
Methods and Compositions for Modulating Gene Expression Using Oligonucleotide Based Drugs Administered in vivo or in vitro
|
|
US8962584B2
(en)
|
2009-10-14 |
2015-02-24 |
Yissum Research Development Company Of The Hebrew University Of Jerusalem, Ltd. |
Compositions for controlling Varroa mites in bees
|
|
WO2011056005A2
(ko)
*
|
2009-11-04 |
2011-05-12 |
성균관대학교산학협력단 |
안티센스 가닥에 의한 오프-타겟 효과를 최소화한 신규한 siRNA 구조 및 그 용도
|
|
WO2011072390A1
(en)
*
|
2009-12-16 |
2011-06-23 |
The University Of Western Ontario |
Compositions and methods related to mirna in diabetic conditions
|
|
PE20130649A1
(es)
|
2010-03-08 |
2013-07-13 |
Monsanto Technology Llc |
Moleculas polinucleotidicas para regulacion genetica en plantas
|
|
BR112012024049A2
(pt)
|
2010-03-24 |
2017-03-01 |
Rxi Pharmaceuticals Corp |
interferência de rna em indicações dérmicas e fibróticas
|
|
EP2550000A4
(en)
|
2010-03-24 |
2014-03-26 |
Advirna Inc |
RNAI COMPOUNDS OF REDUCED SIZE ADMINISTERING
|
|
CN106074591B
(zh)
|
2010-03-24 |
2020-01-14 |
菲奥医药公司 |
眼部症候中的rna干扰
|
|
DK2561078T3
(en)
|
2010-04-23 |
2019-01-14 |
Cold Spring Harbor Laboratory |
NEW STRUCTURALLY DESIGNED SHRNAs
|
|
GB201006841D0
(en)
*
|
2010-04-26 |
2010-06-09 |
Thomsen Lars |
Method, device and system for targetted cell lysis
|
|
EP2631291B1
(en)
*
|
2010-10-22 |
2019-05-15 |
OliX Pharmaceuticals, Inc. |
Nucleic acid molecules inducing rna interference, and uses thereof
|
|
CN101979558B
(zh)
*
|
2010-10-28 |
2015-09-02 |
百奥迈科生物技术有限公司 |
一种靶向乙型肝炎病毒基因的siRNA分子及其应用
|
|
WO2012140234A1
(en)
|
2011-04-13 |
2012-10-18 |
Vib Vzw |
Modulation of mirna in diseases with aberrant angiogenesis
|
|
WO2012149646A1
(en)
*
|
2011-05-05 |
2012-11-08 |
Sunnybrook Research Institute |
Mirna inhibitors and their uses
|
|
CA2844012C
(en)
|
2011-08-04 |
2021-03-16 |
Yeda Research And Development Co. Ltd. |
Micro-rnas and compositions comprising same for the treatment and diagnosis of serotonin-, adrenalin-, noradrenalin-, glutamate-, and corticotropin-releasing hormone- associated medical conditions
|
|
US10806146B2
(en)
|
2011-09-13 |
2020-10-20 |
Monsanto Technology Llc |
Methods and compositions for weed control
|
|
US10829828B2
(en)
|
2011-09-13 |
2020-11-10 |
Monsanto Technology Llc |
Methods and compositions for weed control
|
|
US10760086B2
(en)
|
2011-09-13 |
2020-09-01 |
Monsanto Technology Llc |
Methods and compositions for weed control
|
|
EP2755466A4
(en)
|
2011-09-13 |
2015-04-15 |
Monsanto Technology Llc |
METHOD AND COMPOSITIONS FOR WEED CONTROL
|
|
EP2766482B1
(en)
|
2011-10-11 |
2016-12-07 |
The Brigham and Women's Hospital, Inc. |
Micrornas in neurodegenerative disorders
|
|
US9593331B2
(en)
|
2011-11-02 |
2017-03-14 |
Osaka City University |
Double-stranded nucleic acid molecule for gene expression control
|
|
WO2013138280A1
(en)
*
|
2012-03-12 |
2013-09-19 |
Eaker Shannon |
IMPROVED ENGRAFTMENT POTENTIAL OF EMBRYONIC STEM CELLS AND PLURIPOTENT STEM CELLS USING MICRO RNAs
|
|
DK2853597T3
(en)
|
2012-05-22 |
2019-04-08 |
Olix Pharmaceuticals Inc |
RNA INTERFERENCE-INducing NUCLEIC ACID MOLECULES WITH CELL PENETENING EQUIPMENT AND USE THEREOF
|
|
US10240162B2
(en)
|
2012-05-24 |
2019-03-26 |
A.B. Seeds Ltd. |
Compositions and methods for silencing gene expression
|
|
CN109810977A
(zh)
|
2012-05-26 |
2019-05-28 |
株式会社博纳克 |
具有递送功能的基因表达调控用单链核酸分子
|
|
EP2703498B1
(en)
*
|
2012-08-29 |
2015-01-14 |
Chanel Parfums Beauté |
Inhibitors of micro-RNAs for use for preventing and/or attenuating skin ageing
|
|
US9096853B2
(en)
*
|
2012-09-24 |
2015-08-04 |
U.S. Department Of Veterans Affairs |
Modified siRNA molecules incorporating 5-fluoro-2′-deoxyuridine residues to enhance cytotoxicity
|
|
WO2014063155A1
(en)
|
2012-10-21 |
2014-04-24 |
University Of Rochester |
Thy1 (cd90) as a novel therapy to control adipose tissue accumulation
|
|
WO2014089121A2
(en)
*
|
2012-12-03 |
2014-06-12 |
Thomas Ichim |
Retrograde delivery of cells and nucleic acids for treatment of cardiovascular diseases
|
|
WO2014123935A1
(en)
*
|
2013-02-05 |
2014-08-14 |
1Globe Health Institute Llc |
Biodegradable and clinically-compatible nanop articles as drug delivery carriers
|
|
WO2014164761A1
(en)
|
2013-03-13 |
2014-10-09 |
Monsanto Technology Llc |
Methods and compositions for weed control
|
|
EP2967082A4
(en)
|
2013-03-13 |
2016-11-02 |
Monsanto Technology Llc |
METHOD AND COMPOSITIONS FOR WEED CONTROL
|
|
US10568328B2
(en)
|
2013-03-15 |
2020-02-25 |
Monsanto Technology Llc |
Methods and compositions for weed control
|
|
KR20150139955A
(ko)
|
2013-04-09 |
2015-12-14 |
보스톤 바이오메디칼, 인크. |
암 치료에 사용하기 위한 2-아세틸나프토[2,3-b]푸란-4,9-디온
|
|
JP6668236B2
(ja)
|
2013-07-19 |
2020-03-18 |
モンサント テクノロジー エルエルシー |
Leptinotarsa防除用組成物及びその方法
|
|
MX390055B
(es)
|
2013-11-04 |
2025-03-20 |
Monsanto Technology Llc |
Composiciones y metodos para controlar infestaciones de plagas y parasitos de los artropodos.
|
|
CN106061488B
(zh)
|
2013-12-02 |
2021-04-09 |
菲奥医药公司 |
癌症的免疫治疗
|
|
UA119253C2
(uk)
|
2013-12-10 |
2019-05-27 |
Біолоджикс, Інк. |
Спосіб боротьби із вірусом у кліща varroa та у бджіл
|
|
US10612020B2
(en)
|
2013-12-26 |
2020-04-07 |
Tokyo Medical University |
Artificial mimic miRNA for controlling gene expression, and use of same
|
|
WO2015099187A1
(ja)
|
2013-12-27 |
2015-07-02 |
株式会社ボナック |
遺伝子発現制御のための人工マッチ型miRNAおよびその用途
|
|
CN105979770B
(zh)
|
2014-01-15 |
2019-07-05 |
孟山都技术公司 |
用于使用epsps多核苷酸的杂草控制的方法和组合物
|
|
CN106715695B
(zh)
|
2014-02-05 |
2020-07-31 |
耶达研究及发展有限公司 |
用于治疗和诊断的微rna和包含所述微rna的组合物
|
|
TW201620525A
(zh)
*
|
2014-03-14 |
2016-06-16 |
波士頓生醫公司 |
使k-ras靜默之非對稱干擾rna組成物及其使用方法
|
|
BR112016022711A2
(pt)
|
2014-04-01 |
2017-10-31 |
Monsanto Technology Llc |
composições e métodos para controle de pragas de inseto
|
|
US11279934B2
(en)
|
2014-04-28 |
2022-03-22 |
Phio Pharmaceuticals Corp. |
Methods for treating cancer using nucleic acids targeting MDM2 or MYCN
|
|
US10729785B2
(en)
*
|
2014-05-19 |
2020-08-04 |
BioNTech SE |
Particles comprising protamine and RNA in combination with endosome destabilizing agents
|
|
KR101681669B1
(ko)
*
|
2014-05-27 |
2016-12-02 |
주식회사 제노포커스 |
유전자 침묵에 의한 목적 단백질의 과발현 방법
|
|
WO2015200223A1
(en)
*
|
2014-06-23 |
2015-12-30 |
Monsanto Technology Llc |
Compositions and methods for regulating gene expression via rna interference
|
|
US11807857B2
(en)
|
2014-06-25 |
2023-11-07 |
Monsanto Technology Llc |
Methods and compositions for delivering nucleic acids to plant cells and regulating gene expression
|
|
AU2015296700B2
(en)
|
2014-07-29 |
2021-10-21 |
Monsanto Technology Llc |
Compositions and methods for controlling insect pests
|
|
KR102506169B1
(ko)
|
2014-09-05 |
2023-03-08 |
피오 파마슈티칼스 코프. |
Tyr 또는 mmp1을 표적화하는 핵산을 사용한 노화 및 피부 장애의 치료 방법
|
|
IL292999A
(en)
|
2014-11-14 |
2022-07-01 |
Voyager Therapeutics Inc |
Compositions and methods of treating amyotrophic lateral sclerosis (als)
|
|
CN112410338A
(zh)
*
|
2014-11-14 |
2021-02-26 |
沃雅戈治疗公司 |
调节性多核苷酸
|
|
JP6637652B2
(ja)
*
|
2014-11-21 |
2020-01-29 |
株式会社バイオシンクタンク |
抗腫瘍剤の選択方法およびその抗腫瘍剤が含有するsiRNA
|
|
US11045488B2
(en)
|
2014-12-26 |
2021-06-29 |
Nitto Denko Corporation |
RNA interference agents for GST-π gene modulation
|
|
US10264976B2
(en)
*
|
2014-12-26 |
2019-04-23 |
The University Of Akron |
Biocompatible flavonoid compounds for organelle and cell imaging
|
|
US11027023B2
(en)
|
2014-12-27 |
2021-06-08 |
Bonac Corporation |
Natural type miRNA for controlling gene expression, and use of same
|
|
US10968449B2
(en)
|
2015-01-22 |
2021-04-06 |
Monsanto Technology Llc |
Compositions and methods for controlling Leptinotarsa
|
|
CN104673796A
(zh)
*
|
2015-02-09 |
2015-06-03 |
暨南大学 |
靶向hsv-1病毒ul18基因的小干扰rna及应用
|
|
US20180080023A1
(en)
*
|
2015-03-16 |
2018-03-22 |
MiRagen Therapeutics, Inc. |
Mirna mimetics and their use in treating sensory conditions
|
|
US11142769B2
(en)
|
2015-03-27 |
2021-10-12 |
Bonac Corporation |
Single-stranded nucleic acid molecule having delivery function and gene expression regulating ability
|
|
WO2016161388A1
(en)
|
2015-04-03 |
2016-10-06 |
University Of Massachusetts |
Fully stabilized asymmetric sirna
|
|
US10883103B2
(en)
|
2015-06-02 |
2021-01-05 |
Monsanto Technology Llc |
Compositions and methods for delivery of a polynucleotide into a plant
|
|
EP3302030A4
(en)
|
2015-06-03 |
2019-04-24 |
Monsanto Technology LLC |
METHOD AND COMPOSITIONS FOR INTRODUCING NUCLEIC ACIDS IN PLANTS
|
|
WO2016196935A1
(en)
|
2015-06-03 |
2016-12-08 |
Boston Biomedical, Inc. |
Compositions comprising a cancer stemness inhibitor and an immunotherapeutic agent for use in treating cancer
|
|
WO2016197024A2
(en)
|
2015-06-05 |
2016-12-08 |
MiRagen Therapeutics, Inc. |
Mir-155 inhibitors for treating cutaneous t cell lymphoma (ctcl)
|
|
US11001845B2
(en)
|
2015-07-06 |
2021-05-11 |
Phio Pharmaceuticals Corp. |
Nucleic acid molecules targeting superoxide dismutase 1 (SOD1)
|
|
US10808247B2
(en)
|
2015-07-06 |
2020-10-20 |
Phio Pharmaceuticals Corp. |
Methods for treating neurological disorders using a synergistic small molecule and nucleic acids therapeutic approach
|
|
WO2017030973A1
(en)
|
2015-08-14 |
2017-02-23 |
University Of Massachusetts |
Bioactive conjugates for oligonucleotide delivery
|
|
GB201516685D0
(en)
*
|
2015-09-21 |
2015-11-04 |
Varghese Oommen P And Oommen Oommen P |
Nucleic acid molecules with enhanced activity
|
|
CN109563509B
(zh)
|
2015-10-19 |
2022-08-09 |
菲奥医药公司 |
靶向长非编码rna的减小尺寸的自递送核酸化合物
|
|
EP3377630A4
(en)
|
2015-11-16 |
2020-01-01 |
Olix Pharmaceuticals, Inc. |
Treatment of age-related macular degeneration using rna complexes that target myd88 or tlr3
|
|
WO2017100127A1
(en)
|
2015-12-06 |
2017-06-15 |
Boston Biomedical, Inc. |
ASYMMETRIC INTERFERING RNAs, AND COMPOSITIONS, USE, OR PREPARATION THEREOF
|
|
US10358647B2
(en)
|
2015-12-13 |
2019-07-23 |
Nitto Denko Corporation |
siRNA structures for high activity and reduced off target
|
|
US10478503B2
(en)
|
2016-01-31 |
2019-11-19 |
University Of Massachusetts |
Branched oligonucleotides
|
|
JP6944942B2
(ja)
|
2016-02-02 |
2021-10-06 |
オリックス ファーマシューティカルズ,インコーポレーテッド |
IL4Rα、TRPA1、またはF2RL1を標的とするRNA複合体を用いたアトピー性皮膚炎および喘息の治療
|
|
EP3411481A4
(en)
|
2016-02-02 |
2020-02-26 |
Olix Pharmaceuticals, Inc. |
TREATMENT OF DISEASES ASSOCIATED WITH ANGIOGENESIS USING ANGPT2 AND PDGFB TARGETED RNA COMPLEXES
|
|
US20190192687A1
(en)
*
|
2016-02-12 |
2019-06-27 |
The United States Of America, As Represented By The Secretary, Dept. Of Health And Human Service |
Rna/dna hybrid nanoparticles modified with single stranded rna toeholds and uses thereof
|
|
KR102775461B1
(ko)
*
|
2016-04-01 |
2025-02-28 |
어비디티 바이오사이언시스 인크. |
핵산-폴리펩타이드 조성물 및 이의 용도
|
|
WO2017178883A2
(en)
|
2016-04-11 |
2017-10-19 |
Olix Pharmaceuticals, Inc. |
Treatment of idiopathic pulmonary fibrosis using rna complexes that target connective tissue growth factor
|
|
KR20220108216A
(ko)
|
2016-05-18 |
2022-08-02 |
보이저 테라퓨틱스, 인크. |
헌팅톤 질환을 치료하기 위한 조성물 및 방법
|
|
SG11201809699XA
(en)
|
2016-05-18 |
2018-12-28 |
Voyager Therapeutics Inc |
Modulatory polynucleotides
|
|
CA3029596A1
(en)
|
2016-06-28 |
2018-01-04 |
Boston Biomedical, Inc. |
Methods for treating cancer
|
|
KR101916652B1
(ko)
|
2016-06-29 |
2018-11-08 |
올릭스 주식회사 |
작은 간섭 rna의 rna 간섭효과 증진용 화합물 및 이의 용도
|
|
CN107630015B
(zh)
|
2016-07-19 |
2021-03-09 |
上海市东方医院 |
一种稳定的dna-rna双链结构
|
|
US11753638B2
(en)
|
2016-08-12 |
2023-09-12 |
University Of Massachusetts |
Conjugated oligonucleotides
|
|
CN110088278B
(zh)
*
|
2016-10-31 |
2023-08-11 |
e-NA生物科技公司 |
双链核酸分子及其用途
|
|
WO2018098352A2
(en)
|
2016-11-22 |
2018-05-31 |
Jun Oishi |
Targeting kras induced immune checkpoint expression
|
|
JP7106563B2
(ja)
|
2016-11-29 |
2022-07-26 |
スミトモ ファーマ オンコロジー, インコーポレイテッド |
ナフトフラン誘導体、その調製、および使用方法
|
|
EP4410373A3
(en)
*
|
2017-01-31 |
2025-01-08 |
Curigin Co.,Ltd. |
Nucleic acid simultaneously inhibiting expression of mtor gene and stat3 gene
|
|
EP3580339A4
(en)
|
2017-02-10 |
2020-12-23 |
Research & Business Foundation Sungkyunkwan University |
LONG DOUBLE STRAND RNA FOR RNA INTERFERENCE
|
|
WO2018160887A1
(en)
*
|
2017-03-01 |
2018-09-07 |
Boston Biomedical, Inc. |
Pdl1-specific and beta-catenin-specific asymmetric interfering rna compositions, uses or preparation thereof
|
|
JP7167059B2
(ja)
|
2017-04-19 |
2022-11-08 |
フィオ ファーマシューティカルズ コーポレーション |
核酸化合物の局所送達
|
|
SG11201909870SA
(en)
|
2017-05-05 |
2019-11-28 |
Voyager Therapeutics Inc |
Compositions and methods of treating amyotrophic lateral sclerosis (als)
|
|
JP2020518259A
(ja)
|
2017-05-05 |
2020-06-25 |
ボイジャー セラピューティクス インコーポレイテッドVoyager Therapeutics,Inc. |
ハンチントン病治療組成物および方法
|
|
WO2018213424A1
(en)
|
2017-05-17 |
2018-11-22 |
Boston Biomedical, Inc. |
Methods for treating cancer
|
|
CA3064590A1
(en)
*
|
2017-06-23 |
2018-12-27 |
University Of Massachusetts |
Two-tailed self-delivering sirna and related methods
|
|
EP3647423A4
(en)
*
|
2017-06-30 |
2021-03-24 |
National University Corporation Tokyo Medical and Dental University |
DOUBLE STRANDED HETERO-ANTI-MIRNA
|
|
US12054711B2
(en)
|
2017-07-14 |
2024-08-06 |
City Of Hope |
Meta-stable oligonucleotides junctions for delivery of therapeutics
|
|
WO2019033079A1
(en)
|
2017-08-10 |
2019-02-14 |
City Of Hope |
CONDITIONAL RNAIDS AND THEIR USES IN THE TREATMENT OF CARDIAC HYPERTROPHY
|
|
EP3696270A4
(en)
|
2017-10-11 |
2021-07-07 |
Nitto Denko Corporation |
REGULATION OF THE EXPRESSION OF NUCLEIC ACID MOLECULES
|
|
US11434502B2
(en)
|
2017-10-16 |
2022-09-06 |
Voyager Therapeutics, Inc. |
Treatment of amyotrophic lateral sclerosis (ALS)
|
|
EP4454654A3
(en)
|
2017-10-16 |
2025-02-19 |
Voyager Therapeutics, Inc. |
Treatment of amyotrophic lateral sclerosis (als)
|
|
WO2019103581A1
(ko)
*
|
2017-11-27 |
2019-05-31 |
(주)프로스테믹스 |
이중 가닥의 올리고뉴클레오티드 및 그 제조 방법
|
|
CN118638788A
(zh)
|
2017-12-06 |
2024-09-13 |
艾维迪提生物科学公司 |
治疗肌萎缩和强直性肌营养不良的组合物和方法
|
|
WO2019195765A1
(en)
|
2018-04-06 |
2019-10-10 |
University Of Massachusetts |
Mlk-regulated micrornas in angiogenesis and tumor development
|
|
WO2020027641A1
(ko)
*
|
2018-08-03 |
2020-02-06 |
주식회사 레모넥스 |
아토피성 질환 예방 또는 치료용 약학적 조성물
|
|
WO2020033899A1
(en)
|
2018-08-10 |
2020-02-13 |
University Of Massachusetts |
Modified oligonucleotides targeting snps
|
|
JP7627042B2
(ja)
|
2018-08-23 |
2025-02-05 |
ユニバーシティー オブ マサチューセッツ |
O-メチルリッチ完全安定化オリゴヌクレオチド
|
|
EP3877519B1
(en)
|
2018-11-09 |
2026-03-11 |
Ginkgo Bioworks, Inc. |
Biosynthesis of mogrosides
|
|
WO2020150636A1
(en)
|
2019-01-18 |
2020-07-23 |
University Of Massachusetts |
Dynamic pharmacokinetic-modifying anchors
|
|
WO2020149702A1
(ko)
*
|
2019-01-18 |
2020-07-23 |
올릭스 주식회사 |
Nrl(neural retina leucine zipper)의 발현을 억제하는 비대칭 sirna
|
|
AU2020268798A1
(en)
*
|
2019-05-03 |
2021-11-04 |
Dicerna Pharmaceuticals, Inc. |
Double-stranded nucleic acid inhibitor molecules with shortened sense strands
|
|
CA3149835A1
(en)
|
2019-08-09 |
2021-02-18 |
University Of Massachusetts |
Chemically modified oligonucleotides targeting snps
|
|
US12365894B2
(en)
|
2019-09-16 |
2025-07-22 |
University Of Massachusetts |
Branched lipid conjugates of siRNA for specific tissue delivery
|
|
WO2021188390A1
(en)
|
2020-03-19 |
2021-09-23 |
Avidity Biosciences, Inc. |
Compositions and methods of treating facioscapulohumeral muscular dystrophy
|
|
WO2021216548A1
(en)
*
|
2020-04-21 |
2021-10-28 |
University Of Massachusetts |
Methods and compositions for treatment of age-related macular degeneration
|
|
EP4157289A4
(en)
|
2020-05-26 |
2024-06-26 |
University Of Massachusetts |
Synthetic oligonucleotides having regions of block and cluster modifications
|
|
US20250034561A1
(en)
|
2021-02-18 |
2025-01-30 |
Oneglobe Holdings Limited |
Novel Compositions for Conjugating Oligonucleotides and Carbohydrates
|
|
US20240352456A1
(en)
|
2021-05-13 |
2024-10-24 |
The United States Of America, As Represented By The Secretary, Department Of Health & Human Services |
Compositions and methods for treating sickle cell diseases
|
|
KR20240014533A
(ko)
|
2021-05-29 |
2024-02-01 |
1글로브 헬스 인스티튜트 엘엘씨 |
신규한 유전자 침묵 기술로서의 짧은 듀플렉스 dna 및 이의 용도
|
|
CA3221935A1
(en)
|
2021-05-29 |
2022-12-08 |
1Globe Health Institute Llc |
Asymmetric short duplex dna as a novel gene silencing technology and use thereof
|
|
AR126207A1
(es)
|
2021-06-23 |
2023-09-27 |
Univ Massachusetts |
Compuestos de oligonucleotidos anti-flt1 optimizados para el tratamiento de la preeclampsia y otros desordenes angiogénicos
|
|
WO2023001234A1
(en)
*
|
2021-07-22 |
2023-01-26 |
Microbio (Shanghai) Co., Ltd. |
Modified small interfering rna molecules with reduced off-target effects
|
|
MX2024003266A
(es)
|
2021-09-16 |
2024-04-03 |
Avidity Biosciences Inc |
Composiciones y metodos de tratamiento de la distrofia muscular facioescapulohumeral.
|
|
WO2023081500A2
(en)
*
|
2021-11-08 |
2023-05-11 |
Dicerna Pharmaceuticals, Inc. |
RNAi OLIGONUCLEOTIDE CONJUGATES
|
|
WO2023207615A1
(zh)
*
|
2022-04-26 |
2023-11-02 |
南京明德新药研发有限公司 |
一类含由天然核苷酸组成突出端的双链RNAi化合物
|
|
EP4577244A1
(en)
|
2022-08-25 |
2025-07-02 |
1Globe Health Institute LLC |
Novel compositions for conjugating oligonucleotides and carbohydrates
|
|
JP2025542580A
(ja)
*
|
2022-12-08 |
2025-12-26 |
1グローブ ヘルス インスティテュート エルエルシー |
遺伝子サイレンシング技術としての、デオキシリボヌクレオチドが散在している短鎖二重鎖rna、およびその使用
|
|
WO2025049599A1
(en)
|
2023-08-29 |
2025-03-06 |
President And Fellows Of Harvard College |
Methods for treating muscle-related disorders by modulating prolyl hydroxylase 3
|
|
WO2025184876A1
(zh)
*
|
2024-03-07 |
2025-09-12 |
竣莅医药科技(无锡)有限公司 |
一种rna干扰触发分子与对应核酸干扰药物制剂及其用途
|
|
CN118460650B
(zh)
*
|
2024-07-10 |
2025-02-14 |
凯莱英医药集团(天津)股份有限公司 |
一种Nedosiran的制备方法
|