JP2010536740A5 - - Google Patents
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- Publication number
- JP2010536740A5 JP2010536740A5 JP2010520669A JP2010520669A JP2010536740A5 JP 2010536740 A5 JP2010536740 A5 JP 2010536740A5 JP 2010520669 A JP2010520669 A JP 2010520669A JP 2010520669 A JP2010520669 A JP 2010520669A JP 2010536740 A5 JP2010536740 A5 JP 2010536740A5
- Authority
- JP
- Japan
- Prior art keywords
- methyl
- thiazole
- amino
- carbonyl
- amide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IB2007053249 | 2007-08-15 | ||
| PCT/IB2008/053264 WO2009022311A2 (en) | 2007-08-15 | 2008-08-14 | 1,2-diamido-ethylene derivatives as orexin antagonists |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010536740A JP2010536740A (ja) | 2010-12-02 |
| JP2010536740A5 true JP2010536740A5 (enExample) | 2011-09-15 |
Family
ID=40206260
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010520669A Ceased JP2010536740A (ja) | 2007-08-15 | 2008-08-14 | １，２−ジアミド−エチレン誘導体 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20110263662A1 (enExample) |
| EP (1) | EP2188282B1 (enExample) |
| JP (1) | JP2010536740A (enExample) |
| KR (1) | KR20100055464A (enExample) |
| CN (1) | CN101778846B (enExample) |
| AU (1) | AU2008288151A1 (enExample) |
| BR (1) | BRPI0815079A2 (enExample) |
| CA (1) | CA2694993A1 (enExample) |
| ES (1) | ES2400830T3 (enExample) |
| MX (1) | MX2010001575A (enExample) |
| RU (1) | RU2010109455A (enExample) |
| WO (1) | WO2009022311A2 (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8084601B2 (en) | 2008-09-11 | 2011-12-27 | Royal Holloway And Bedford New College Royal Holloway, University Of London | Oligomers |
| CA2739344A1 (en) * | 2008-10-14 | 2010-04-22 | Actelion Pharmaceuticals Ltd | Phenethylamide derivatives and their heterocyclic analogues |
| JP5847087B2 (ja) | 2009-10-23 | 2016-01-20 | ヤンセン ファーマシューティカ エヌ．ベー． | オレキシン受容体調節因子としての縮合複素環式化合物 |
| ME03452B (me) | 2009-10-23 | 2020-01-20 | Janssen Pharmaceutica Nv | Disupstituisani oktahi-dropirolo[3,4-c]piroli kao modulatori oreksin receptora |
| WO2011050202A1 (en) | 2009-10-23 | 2011-04-28 | Janssen Pharmaceutica Nv | Fused heterocyclic compounds as orexin receptor modulators |
| WO2011073316A1 (en) * | 2009-12-18 | 2011-06-23 | Novartis Ag | 4-aryl-butane-1,3-diamides |
| CA2815179A1 (en) * | 2010-11-10 | 2012-05-18 | Actelion Pharmaceuticals Ltd | Lactam derivatives useful as orexin receptor antagonists |
| WO2012145581A1 (en) | 2011-04-20 | 2012-10-26 | Janssen Pharmaceutica Nv | Disubstituted octahy-dropyrrolo [3,4-c] pyrroles as orexin receptor modulators |
| CA2863413A1 (en) | 2012-02-07 | 2013-08-15 | Eolas Therapeutics, Inc. | Substituted prolines / piperidines as orexin receptor antagonists |
| US9440982B2 (en) | 2012-02-07 | 2016-09-13 | Eolas Therapeutics, Inc. | Substituted prolines/piperidines as orexin receptor antagonists |
| AR098436A1 (es) * | 2013-11-19 | 2016-05-26 | Actelion Pharmaceuticals Ltd | Compuestos tricíclicos de piperidina |
| UY36272A (es) | 2014-08-13 | 2016-02-29 | Eolas Therapeutics Inc | Difluoropirrolidinas como moduladores de los receptores de orexinas |
| GB201415569D0 (en) * | 2014-09-03 | 2014-10-15 | C4X Discovery Ltd | Therapeutic Compounds |
| GB201601703D0 (en) | 2016-01-29 | 2016-03-16 | C4X Discovery Ltd | Therapeutic compounds |
| AU2017217931B2 (en) | 2016-02-12 | 2020-10-22 | Astrazeneca Ab | Halo-substituted piperidines as orexin receptor modulators |
| MD3426251T2 (ro) | 2016-03-10 | 2022-09-30 | Janssen Pharmaceutica Nv | Metode de tratament al depresiei utilizând antagoniști ai receptorului orexină-2 |
| WO2017194548A1 (en) | 2016-05-10 | 2017-11-16 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods and pharmaceutical compositions for the treatment of autoimmune inflammatory diseases |
| GB201702174D0 (en) | 2017-02-09 | 2017-03-29 | Benevolentai Bio Ltd | Orexin receptor antagonists |
| GB201707504D0 (en) | 2017-05-10 | 2017-06-21 | Benevolentai Bio Ltd | Orexin receptor antagonists |
| GB201707499D0 (en) | 2017-05-10 | 2017-06-21 | Benevolentai Bio Ltd | Orexin receptor antagonists |
| WO2025224168A1 (en) | 2024-04-24 | 2025-10-30 | Idorsia Pharmaceuticals Ltd | Aryl sulfone and sulfanone derivatives as orexin receptor modulators |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2381995A (en) | 1994-04-29 | 1995-11-29 | Pharmacia & Upjohn Company | Methanol derivatives for treatment of retroviral infections especially hiv infections |
| ES2238458T3 (es) | 2000-06-16 | 2005-09-01 | Smithkline Beecham Plc | Piperidinas para uso como antagonistas de los receptores de orexina. |
| JP4028711B2 (ja) * | 2001-10-31 | 2007-12-26 | 株式会社アーレスティ | 金型冷却装置 |
| GB0130341D0 (en) * | 2001-12-19 | 2002-02-06 | Smithkline Beecham Plc | Compounds |
-
2008
- 2008-08-14 KR KR1020107005493A patent/KR20100055464A/ko not_active Withdrawn
- 2008-08-14 WO PCT/IB2008/053264 patent/WO2009022311A2/en not_active Ceased
- 2008-08-14 RU RU2010109455/04A patent/RU2010109455A/ru not_active Application Discontinuation
- 2008-08-14 MX MX2010001575A patent/MX2010001575A/es not_active Application Discontinuation
- 2008-08-14 JP JP2010520669A patent/JP2010536740A/ja not_active Ceased
- 2008-08-14 BR BRPI0815079-6A2A patent/BRPI0815079A2/pt not_active IP Right Cessation
- 2008-08-14 CN CN2008801035335A patent/CN101778846B/zh not_active Expired - Fee Related
- 2008-08-14 ES ES08807317T patent/ES2400830T3/es active Active
- 2008-08-14 EP EP08807317A patent/EP2188282B1/en not_active Not-in-force
- 2008-08-14 US US12/673,382 patent/US20110263662A1/en not_active Abandoned
- 2008-08-14 AU AU2008288151A patent/AU2008288151A1/en not_active Abandoned
- 2008-08-14 CA CA2694993A patent/CA2694993A1/en not_active Abandoned
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