JP2010536740A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2010536740A5 JP2010536740A5 JP2010520669A JP2010520669A JP2010536740A5 JP 2010536740 A5 JP2010536740 A5 JP 2010536740A5 JP 2010520669 A JP2010520669 A JP 2010520669A JP 2010520669 A JP2010520669 A JP 2010520669A JP 2010536740 A5 JP2010536740 A5 JP 2010536740A5
- Authority
- JP
- Japan
- Prior art keywords
- methyl
- thiazole
- amino
- carbonyl
- amide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IB2007053249 | 2007-08-15 | ||
| PCT/IB2008/053264 WO2009022311A2 (en) | 2007-08-15 | 2008-08-14 | 1,2-diamido-ethylene derivatives as orexin antagonists |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010536740A JP2010536740A (ja) | 2010-12-02 |
| JP2010536740A5 true JP2010536740A5 (enExample) | 2011-09-15 |
Family
ID=40206260
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010520669A Ceased JP2010536740A (ja) | 2007-08-15 | 2008-08-14 | １，２−ジアミド−エチレン誘導体 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20110263662A1 (enExample) |
| EP (1) | EP2188282B1 (enExample) |
| JP (1) | JP2010536740A (enExample) |
| KR (1) | KR20100055464A (enExample) |
| CN (1) | CN101778846B (enExample) |
| AU (1) | AU2008288151A1 (enExample) |
| BR (1) | BRPI0815079A2 (enExample) |
| CA (1) | CA2694993A1 (enExample) |
| ES (1) | ES2400830T3 (enExample) |
| MX (1) | MX2010001575A (enExample) |
| RU (1) | RU2010109455A (enExample) |
| WO (1) | WO2009022311A2 (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8084601B2 (en) | 2008-09-11 | 2011-12-27 | Royal Holloway And Bedford New College Royal Holloway, University Of London | Oligomers |
| BRPI0920183A2 (pt) * | 2008-10-14 | 2018-05-22 | Actelion Pharmaceuticals Ltd | derivados de fenetilamida e seus analogos heterociclicos |
| WO2011050202A1 (en) | 2009-10-23 | 2011-04-28 | Janssen Pharmaceutica Nv | Fused heterocyclic compounds as orexin receptor modulators |
| WO2011050200A1 (en) | 2009-10-23 | 2011-04-28 | Janssen Pharmaceutica Nv | Fused heterocyclic compounds as orexin receptor modulators |
| MX2012004753A (es) | 2009-10-23 | 2012-09-07 | Janssen Pharmaceutica Nv | Octahidropirrolo[3,4-c]pirrolos disustituidos como moduladores del receptor de orexina. |
| WO2011073316A1 (en) * | 2009-12-18 | 2011-06-23 | Novartis Ag | 4-aryl-butane-1,3-diamides |
| CA2815179A1 (en) * | 2010-11-10 | 2012-05-18 | Actelion Pharmaceuticals Ltd | Lactam derivatives useful as orexin receptor antagonists |
| US9586962B2 (en) | 2011-04-20 | 2017-03-07 | Janssen Pharmaceutica Nv | Disubstituted octahydropyrrolo [3,4-C] pyrroles as orexin receptor modulators |
| US9440982B2 (en) | 2012-02-07 | 2016-09-13 | Eolas Therapeutics, Inc. | Substituted prolines/piperidines as orexin receptor antagonists |
| RU2014136339A (ru) | 2012-02-07 | 2016-03-27 | Иолас Терапьютикс, Инк. | Замещенные пролины/пиперидины как антагонисты орексиновых рецепторов |
| AR098436A1 (es) * | 2013-11-19 | 2016-05-26 | Actelion Pharmaceuticals Ltd | Compuestos tricíclicos de piperidina |
| EP3180332B1 (en) | 2014-08-13 | 2021-10-27 | Eolas Therapeutics Inc. | Difluoropyrrolidines as orexin receptor modulators |
| GB201415569D0 (en) * | 2014-09-03 | 2014-10-15 | C4X Discovery Ltd | Therapeutic Compounds |
| GB201601703D0 (en) | 2016-01-29 | 2016-03-16 | C4X Discovery Ltd | Therapeutic compounds |
| KR102738491B1 (ko) | 2016-02-12 | 2024-12-03 | 아스트라제네카 아베 | 오렉신 수용체 조정제로서의 할로-치환된 피페리딘 |
| RS63296B1 (sr) | 2016-03-10 | 2022-07-29 | Janssen Pharmaceutica Nv | Metode lečenja depresije korišćenjem antagonista receptora oreksin-2 |
| US20190151304A1 (en) | 2016-05-10 | 2019-05-23 | Inserm (Institut National De La Santé Et De La Rechercjae Médicale | Methods and pharmaceutical compositions for the treatment of autoimmune inflammatory |
| GB201702174D0 (en) | 2017-02-09 | 2017-03-29 | Benevolentai Bio Ltd | Orexin receptor antagonists |
| GB201707504D0 (en) | 2017-05-10 | 2017-06-21 | Benevolentai Bio Ltd | Orexin receptor antagonists |
| GB201707499D0 (en) | 2017-05-10 | 2017-06-21 | Benevolentai Bio Ltd | Orexin receptor antagonists |
| WO2025224168A1 (en) | 2024-04-24 | 2025-10-30 | Idorsia Pharmaceuticals Ltd | Aryl sulfone and sulfanone derivatives as orexin receptor modulators |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1995029922A1 (en) | 1994-04-29 | 1995-11-09 | Pharmacia & Upjohn Company | Methanol derivatives for treatment of retroviral infections especially hiv infections |
| ES2238458T3 (es) | 2000-06-16 | 2005-09-01 | Smithkline Beecham Plc | Piperidinas para uso como antagonistas de los receptores de orexina. |
| JP4028711B2 (ja) * | 2001-10-31 | 2007-12-26 | 株式会社アーレスティ | 金型冷却装置 |
| GB0130341D0 (en) | 2001-12-19 | 2002-02-06 | Smithkline Beecham Plc | Compounds |
-
2008
- 2008-08-14 ES ES08807317T patent/ES2400830T3/es active Active
- 2008-08-14 WO PCT/IB2008/053264 patent/WO2009022311A2/en not_active Ceased
- 2008-08-14 JP JP2010520669A patent/JP2010536740A/ja not_active Ceased
- 2008-08-14 BR BRPI0815079-6A2A patent/BRPI0815079A2/pt not_active IP Right Cessation
- 2008-08-14 CN CN2008801035335A patent/CN101778846B/zh not_active Expired - Fee Related
- 2008-08-14 US US12/673,382 patent/US20110263662A1/en not_active Abandoned
- 2008-08-14 AU AU2008288151A patent/AU2008288151A1/en not_active Abandoned
- 2008-08-14 RU RU2010109455/04A patent/RU2010109455A/ru not_active Application Discontinuation
- 2008-08-14 MX MX2010001575A patent/MX2010001575A/es not_active Application Discontinuation
- 2008-08-14 EP EP08807317A patent/EP2188282B1/en not_active Not-in-force
- 2008-08-14 KR KR1020107005493A patent/KR20100055464A/ko not_active Withdrawn
- 2008-08-14 CA CA2694993A patent/CA2694993A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2010536740A5 (enExample) | ||
| JP2010534646A5 (enExample) | ||
| JP2010534647A5 (enExample) | ||
| RU2010109455A (ru) | Производные 1,2-диамидоэтилена в качестве антагонистов орексина | |
| RU2460732C2 (ru) | Производные 2-аза-бицикло[3.1.0.]гексана в качестве антагонистов рецептора орексина | |
| RU2010138640A (ru) | Производные 2-аза-бицикло [2.2.1] гептана | |
| US7897572B1 (en) | Theraputic methods for type I diabetes | |
| ES2350460T3 (es) | Derivados de 3-aza-biciclo[3.1.0]hexano. | |
| DE69916881T2 (de) | Antihypertriglyceridemische, antihyperglykemische, antiangiogene und wundheilende substituierte indolalkansäure | |
| RS59600B1 (sr) | Stabilizovane kompozicije neproteinskog toksina klostridije | |
| JP2010535816A5 (enExample) | ||
| JP2020512337A5 (enExample) | ||
| JP2010514751A5 (enExample) | ||
| JP2007520440A5 (enExample) | ||
| TW201002703A (en) | Quinazolinedione derivatives as TRPA1 modulators | |
| KR20100041805A (ko) | 3-아자-비시클로[3.3.0]옥탄 화합물 | |
| JP2009503114A5 (enExample) | ||
| RU2010106854A (ru) | Производные 2-аза-бицикло[3.3.0]октана | |
| JP2009515887A5 (enExample) | ||
| WO2005018672A1 (ja) | キマーゼ阻害剤を有効成分として含有する薬剤 | |
| CN102333766A (zh) | 甲酰胺化合物和它们作为需钙蛋白酶抑制剂的用途 | |
| JP2010523727A5 (enExample) | ||
| JP2005521705A5 (enExample) | ||
| US8748422B2 (en) | Pharmaceutical compositions containing quinazoline derivatives for treating as serotonin receptor antagonist | |
| CN107629022B (zh) | 一种抗菌增效剂及其制法和用途 |