KR20100055464A - 오렉신 길항제로서의 1,2-디아미도-에틸렌 유도체 - Google Patents

오렉신 길항제로서의 1,2-디아미도-에틸렌 유도체 Download PDF

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KR20100055464A
KR20100055464A KR1020107005493A KR20107005493A KR20100055464A KR 20100055464 A KR20100055464 A KR 20100055464A KR 1020107005493 A KR1020107005493 A KR 1020107005493A KR 20107005493 A KR20107005493 A KR 20107005493A KR 20100055464 A KR20100055464 A KR 20100055464A
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methyl
thiazole
amino
carboxylic acid
carbonyl
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Korean (ko)
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아메드 애자위
크리슈토프 보쓰
마르쿠스 구데
랄프 코베르슈타인
띠에리 시페랑
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액테리온 파마슈티칼 리미티드
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Publication of KR20100055464A publication Critical patent/KR20100055464A/ko
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    • C—CHEMISTRY; METALLURGY
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    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
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    • C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
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    • C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
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    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

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KR1020107005493A 2007-08-15 2008-08-14 오렉신 길항제로서의 1,2-디아미도-에틸렌 유도체 Withdrawn KR20100055464A (ko)

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US (1) US20110263662A1 (enExample)
EP (1) EP2188282B1 (enExample)
JP (1) JP2010536740A (enExample)
KR (1) KR20100055464A (enExample)
CN (1) CN101778846B (enExample)
AU (1) AU2008288151A1 (enExample)
BR (1) BRPI0815079A2 (enExample)
CA (1) CA2694993A1 (enExample)
ES (1) ES2400830T3 (enExample)
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20160077216A (ko) * 2013-11-19 2016-07-01 액테리온 파마슈티칼 리미티드 트리시클릭 피페리딘 화합물
KR20170044204A (ko) * 2014-09-03 2017-04-24 씨4엑스 디스커버리 리미티드 오렉신―１ 수용체의 억제제로서의 치료 화합물

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8084601B2 (en) 2008-09-11 2011-12-27 Royal Holloway And Bedford New College Royal Holloway, University Of London Oligomers
WO2010044054A1 (en) * 2008-10-14 2010-04-22 Actelion Pharmaceuticals Ltd Phenethylamide derivatives and their heterocyclic analogues
US8680275B2 (en) 2009-10-23 2014-03-25 Janssen Pharmaceutica Nv Fused heterocyclic compounds as orexin receptor modulators
KR101859409B1 (ko) 2009-10-23 2018-05-18 얀센 파마슈티카 엔.브이. 오렉신 수용체 조절제로서의 이치환된 옥타하이드로피롤로［3,4-ｃ］피롤
US9062044B2 (en) 2009-10-23 2015-06-23 Janssen Pharmaceutica Nv Disubstituted octahydropyrrolo[3,4-c]pyrroles as orexin receptor modulators
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CA2694993A1 (en) 2009-02-19
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