KR20100055464A - 오렉신 길항제로서의 1,2-디아미도-에틸렌 유도체 - Google Patents

오렉신 길항제로서의 1,2-디아미도-에틸렌 유도체 Download PDF

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KR20100055464A
KR20100055464A KR1020107005493A KR20107005493A KR20100055464A KR 20100055464 A KR20100055464 A KR 20100055464A KR 1020107005493 A KR1020107005493 A KR 1020107005493A KR 20107005493 A KR20107005493 A KR 20107005493A KR 20100055464 A KR20100055464 A KR 20100055464A
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methyl
thiazole
amino
carboxylic acid
carbonyl
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Korean (ko)
Inventor
아메드 애자위
크리슈토프 보쓰
마르쿠스 구데
랄프 코베르슈타인
띠에리 시페랑
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액테리온 파마슈티칼 리미티드
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Publication of KR20100055464A publication Critical patent/KR20100055464A/ko
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    • C—CHEMISTRY; METALLURGY
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    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
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    • C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
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    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

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KR1020107005493A 2007-08-15 2008-08-14 오렉신 길항제로서의 1,2-디아미도-에틸렌 유도체 Withdrawn KR20100055464A (ko)

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IB2007053249 2007-08-15

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US (1) US20110263662A1 (enExample)
EP (1) EP2188282B1 (enExample)
JP (1) JP2010536740A (enExample)
KR (1) KR20100055464A (enExample)
CN (1) CN101778846B (enExample)
AU (1) AU2008288151A1 (enExample)
BR (1) BRPI0815079A2 (enExample)
CA (1) CA2694993A1 (enExample)
ES (1) ES2400830T3 (enExample)
MX (1) MX2010001575A (enExample)
RU (1) RU2010109455A (enExample)
WO (1) WO2009022311A2 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20160077216A (ko) * 2013-11-19 2016-07-01 액테리온 파마슈티칼 리미티드 트리시클릭 피페리딘 화합물
KR20170044204A (ko) * 2014-09-03 2017-04-24 씨4엑스 디스커버리 리미티드 오렉신―１ 수용체의 억제제로서의 치료 화합물

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US8084601B2 (en) 2008-09-11 2011-12-27 Royal Holloway And Bedford New College Royal Holloway, University Of London Oligomers
RU2011119217A (ru) * 2008-10-14 2012-11-27 Актелион Фармасьютикалз Лтд Производные фенетиламида и их гетероциклические аналоги
ME03452B (me) 2009-10-23 2020-01-20 Janssen Pharmaceutica Nv Disupstituisani oktahi-dropirolo[3,4-c]piroli kao modulatori oreksin receptora
EP2491034B1 (en) 2009-10-23 2013-12-18 Janssen Pharmaceutica, N.V. Fused heterocyclic compounds as orexin receptor modulators
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