JP2010533736A5 - - Google Patents
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- Publication number
- JP2010533736A5 JP2010533736A5 JP2010517200A JP2010517200A JP2010533736A5 JP 2010533736 A5 JP2010533736 A5 JP 2010533736A5 JP 2010517200 A JP2010517200 A JP 2010517200A JP 2010517200 A JP2010517200 A JP 2010517200A JP 2010533736 A5 JP2010533736 A5 JP 2010533736A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- amino
- mono
- cycloalkyl
- aminosulfonyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 0 CC(*)(C1(CC(C2)C3)CC3CC2C1)NC(C)=O Chemical compound CC(*)(C1(CC(C2)C3)CC3CC2C1)NC(C)=O 0.000 description 17
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US95062507P | 2007-07-19 | 2007-07-19 | |
| PCT/US2008/070613 WO2009012482A2 (en) | 2007-07-19 | 2008-07-21 | 5-membered heterocyclic amides and related compounds |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013243253A Division JP5813734B2 (ja) | 2007-07-19 | 2013-11-25 | ５員複素環アミドおよび関連化合物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010533736A JP2010533736A (ja) | 2010-10-28 |
| JP2010533736A5 true JP2010533736A5 (index.php) | 2011-09-08 |
Family
ID=40260407
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010517200A Pending JP2010533736A (ja) | 2007-07-19 | 2008-07-21 | ５員複素環アミドおよび関連化合物 |
| JP2013243253A Expired - Fee Related JP5813734B2 (ja) | 2007-07-19 | 2013-11-25 | ５員複素環アミドおよび関連化合物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013243253A Expired - Fee Related JP5813734B2 (ja) | 2007-07-19 | 2013-11-25 | ５員複素環アミドおよび関連化合物 |
Country Status (29)
| Country | Link |
|---|---|
| US (2) | US20100292236A1 (index.php) |
| EP (1) | EP2178865B1 (index.php) |
| JP (2) | JP2010533736A (index.php) |
| KR (2) | KR101593237B1 (index.php) |
| CN (2) | CN104844578B (index.php) |
| AU (1) | AU2008275891B2 (index.php) |
| BR (1) | BRPI0813426A2 (index.php) |
| CA (1) | CA2691507C (index.php) |
| CO (1) | CO6251318A2 (index.php) |
| CY (1) | CY1116809T1 (index.php) |
| DK (1) | DK2178865T3 (index.php) |
| EA (1) | EA017250B1 (index.php) |
| ES (1) | ES2551095T3 (index.php) |
| HK (1) | HK1213879A1 (index.php) |
| HR (1) | HRP20151052T1 (index.php) |
| HU (1) | HUE026446T2 (index.php) |
| IL (1) | IL202499A (index.php) |
| MX (1) | MX2009014159A (index.php) |
| MY (1) | MY154668A (index.php) |
| NZ (1) | NZ582057A (index.php) |
| PH (1) | PH12014501677A1 (index.php) |
| PL (1) | PL2178865T3 (index.php) |
| PT (1) | PT2178865E (index.php) |
| RS (1) | RS54303B1 (index.php) |
| SG (1) | SG187396A1 (index.php) |
| SI (1) | SI2178865T1 (index.php) |
| UA (1) | UA105758C2 (index.php) |
| WO (1) | WO2009012482A2 (index.php) |
| ZA (1) | ZA200908447B (index.php) |
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| US8563573B2 (en) | 2007-11-02 | 2013-10-22 | Vertex Pharmaceuticals Incorporated | Azaindole derivatives as CFTR modulators |
| JP2011506560A (ja) | 2007-12-20 | 2011-03-03 | ノバルティス アーゲー | Ｐｉ３キナーゼ阻害剤として用いられるチアゾール誘導体 |
| CN102056916A (zh) | 2008-06-13 | 2011-05-11 | 拜耳作物科学股份公司 | 作为杀虫剂的新的杂芳族酰胺和硫代酰胺 |
| UA104147C2 (uk) | 2008-09-10 | 2014-01-10 | Новартис Аг | Похідна піролідиндикарбонової кислоти та її застосування у лікуванні проліферативних захворювань |
| AU2009313198B2 (en) | 2008-11-10 | 2016-03-24 | Vertex Pharmaceuticals Incorporated | Compounds useful as inhibitors of ATR kinase |
| MX2011006503A (es) | 2008-12-19 | 2011-09-06 | Vertex Pharma | Derivados de pirazina utiles como inhibidores de la cinasa de atr. |
| US8293753B2 (en) | 2009-07-02 | 2012-10-23 | Novartis Ag | Substituted 2-carboxamide cycloamino ureas |
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| KR20130056244A (ko) | 2010-04-22 | 2013-05-29 | 버텍스 파마슈티칼스 인코포레이티드 | 시클로알킬카르복스아미도-인돌 화합물의 제조 방법 |
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| EP2569287B1 (en) | 2010-05-12 | 2014-07-09 | Vertex Pharmaceuticals Inc. | Compounds useful as inhibitors of atr kinase |
| AU2011253025A1 (en) | 2010-05-12 | 2012-11-29 | Vertex Pharmaceuticals Incorporated | Compounds useful as inhibitors of ATR kinase |
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| CN102947272A (zh) | 2010-05-12 | 2013-02-27 | 沃泰克斯药物股份有限公司 | 用作atr激酶抑制剂的2-氨基吡啶衍生物 |
| WO2011143423A2 (en) | 2010-05-12 | 2011-11-17 | Vertex Pharmaceuticals Incorporated | Compounds useful as inhibitors of atr kinase |
| JP2013529643A (ja) | 2010-06-23 | 2013-07-22 | バーテックス ファーマシューティカルズ インコーポレイテッド | Ａｔｒキナーゼ阻害剤として有用なピロロピラジン誘導体 |
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| CN101921268B (zh) * | 2010-08-27 | 2016-08-03 | 中山大学肿瘤防治中心 | 5-噻唑酰胺类化合物及生物学应用 |
| JP2013249256A (ja) * | 2010-09-15 | 2013-12-12 | Astellas Pharma Inc | 脂肪性肝疾患治療薬 |
| ME02575B (me) | 2010-09-21 | 2017-06-20 | Eisai R&D Man Co Ltd | Farmaceutska kompozicija |
| CN103562204A (zh) | 2011-04-05 | 2014-02-05 | 沃泰克斯药物股份有限公司 | 可用作tra激酶的抑制剂的氨基吡嗪化合物 |
| JP2014517079A (ja) | 2011-06-22 | 2014-07-17 | バーテックス ファーマシューティカルズ インコーポレイテッド | Ａｔｒキナーゼ阻害剤として有用な化合物 |
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| KR20140048257A (ko) * | 2011-07-15 | 2014-04-23 | 바스프 에스이 | 동물 해충을 퇴치하기 위해 치환된 3-피리딜 티아졸 화합물 및 유도체 i을 사용하는 살충 방법 |
| TW201309706A (zh) | 2011-07-22 | 2013-03-01 | Actelion Pharmaceuticals Ltd | 作為ｐ２ｘ７受體拮抗劑之雜環醯胺衍生物 |
| JP2014528419A (ja) | 2011-09-30 | 2014-10-27 | バーテックス ファーマシューティカルズ インコーポレイテッドＶｅｒｔｅｘ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃｏｒｐｏｒａｔｅｄ | Ａｔｒキナーゼ阻害剤として有用な化合物 |
| US8853217B2 (en) | 2011-09-30 | 2014-10-07 | Vertex Pharmaceuticals Incorporated | Compounds useful as inhibitors of ATR kinase |
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| ES2751741T3 (es) | 2011-09-30 | 2020-04-01 | Vertex Pharma | Procedimiento para fabricar compuestos útiles como inhibidores de la quinasa ATR |
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| KR102033190B1 (ko) | 2012-01-20 | 2019-10-16 | 이도르시아 파마슈티컬스 리미티드 | Ｐ２ｘ７ 수용체 길항제로서의 헤테로시클릭 아미드 유도체 |
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| HUE052808T2 (hu) | 2012-12-07 | 2021-05-28 | Vertex Pharma | Pirazolo[1,5-A]pirimidinek alkalmazása ATR kináz inhibítorként, rákos megbetegedések kezelésére |
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| ES2885181T3 (es) | 2014-04-15 | 2021-12-13 | Vertex Pharma | Composiciones farmacéuticas para el tratamiento de enfermedades mediadas por el regulador de la conductancia transmembrana de fibrosis quística |
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