JP2010529969A5 - - Google Patents

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Publication number
JP2010529969A5
JP2010529969A5 JP2010511510A JP2010511510A JP2010529969A5 JP 2010529969 A5 JP2010529969 A5 JP 2010529969A5 JP 2010511510 A JP2010511510 A JP 2010511510A JP 2010511510 A JP2010511510 A JP 2010511510A JP 2010529969 A5 JP2010529969 A5 JP 2010529969A5
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JP
Japan
Prior art keywords
ethylamino
alkyl
butoxyphenyl
compound
disorder
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2010511510A
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English (en)
Japanese (ja)
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JP5440496B2 (ja
JP2010529969A (ja
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Priority claimed from PCT/EP2008/003848 external-priority patent/WO2008151702A1/en
Publication of JP2010529969A publication Critical patent/JP2010529969A/ja
Publication of JP2010529969A5 publication Critical patent/JP2010529969A5/ja
Application granted granted Critical
Publication of JP5440496B2 publication Critical patent/JP5440496B2/ja
Active legal-status Critical Current
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JP2010511510A 2007-06-15 2008-05-14 置換２−［２−（フェニル）エチルアミノ］アルカンアミド誘導体ならびにナトリウムおよび／またはカルシウムチャネル調節剤としてのこれらの使用 Active JP5440496B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07011766.8 2007-06-15
EP07011766 2007-06-15
PCT/EP2008/003848 WO2008151702A1 (en) 2007-06-15 2008-05-14 Substituted 2- [2- (phenyl) ethylamino] alkaneamide derivatives and their use as sodium and/or calcium channel modulators

Publications (3)

Publication Number Publication Date
JP2010529969A JP2010529969A (ja) 2010-09-02
JP2010529969A5 true JP2010529969A5 (enExample) 2012-06-07
JP5440496B2 JP5440496B2 (ja) 2014-03-12

Family

ID=38658156

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010511510A Active JP5440496B2 (ja) 2007-06-15 2008-05-14 置換２−［２−（フェニル）エチルアミノ］アルカンアミド誘導体ならびにナトリウムおよび／またはカルシウムチャネル調節剤としてのこれらの使用

Country Status (27)

Country Link
US (8) US8519000B2 (enExample)
EP (1) EP2155663B1 (enExample)
JP (1) JP5440496B2 (enExample)
KR (1) KR101545124B1 (enExample)
CN (1) CN101687773B (enExample)
AR (1) AR068976A1 (enExample)
AU (1) AU2008261325B2 (enExample)
BR (1) BRPI0813363B8 (enExample)
CA (1) CA2689561C (enExample)
CY (1) CY1119787T1 (enExample)
DK (1) DK2155663T3 (enExample)
EA (1) EA018195B1 (enExample)
ES (1) ES2655704T3 (enExample)
HR (1) HRP20180324T8 (enExample)
HU (1) HUE038113T2 (enExample)
IL (1) IL202235A (enExample)
LT (1) LT2155663T (enExample)
MX (1) MX2009013119A (enExample)
NO (1) NO2155663T3 (enExample)
NZ (1) NZ581288A (enExample)
PL (1) PL2155663T3 (enExample)
PT (1) PT2155663T (enExample)
RS (1) RS56780B1 (enExample)
SI (1) SI2155663T1 (enExample)
TR (1) TR201802576T4 (enExample)
TW (1) TWI400071B (enExample)
WO (1) WO2008151702A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1658062T3 (da) * 2003-08-25 2010-05-31 Newron Pharm Spa Alfa-aminoamid-derivater anvendelige som anti-inflammatoriske midler
JP5213265B2 (ja) * 2009-10-08 2013-06-19 花王株式会社 Ｌｏｘ−１発現調節剤の評価又は選択方法
PT2723710T (pt) * 2011-06-27 2016-11-14 Newron Pharm Spa Derivados fluorados de arilalquilaminocarboxamida
CN103804341B (zh) * 2012-11-13 2018-04-10 中国人民解放军军事医学科学院毒物药物研究所 酰胺衍生物及其医药用途
CN104761531B (zh) * 2014-01-03 2017-12-01 中国人民解放军军事医学科学院毒物药物研究所 镇痛活性化合物及其医药用途
EP3340988B1 (en) * 2015-11-12 2025-04-09 Afasci, Inc. Ion channel inhibitory compounds, pharmaceutical formulations and uses
CN106316824B (zh) * 2016-08-18 2018-10-19 广州康瑞泰药业有限公司 一种合成2-氟环丙烷甲酸的新方法
CN112041296B (zh) * 2018-04-28 2023-12-29 上海璃道医药科技有限公司 包含苯并含氧脂肪环结构的氨基乙酰胺类化合物及其用途
CN112714670A (zh) * 2018-08-30 2021-04-27 沙特基础工业全球技术公司 具有改良异构化的芳构化催化剂、其制造和使用方法
EP3725769A1 (en) 2019-04-17 2020-10-21 Newron Pharmaceuticals S.p.A. Process for the production of substituted 2-[2-(phenyl) ethylamino]alkaneamide derivatives
EP3725768A1 (en) 2019-04-17 2020-10-21 Newron Pharmaceuticals S.p.A. Process for the production of substituted 2-[2-(phenyl) ethylamino]alkaneamide derivatives
EP4615820B1 (en) 2023-04-28 2026-02-04 Newron Pharmaceuticals S.p.A. Crystalline forms of evenamide

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB586645A (en) 1944-07-19 1947-03-26 Burroughs Wellcome Co Improvements relating to the synthesis of amino acid derivatives and salts thereof
GB1254332A (en) * 1969-02-27 1971-11-17 Science Union & Cie Amino acids and their derivatives and processes for preparing them
IL94466A (en) * 1989-05-25 1995-01-24 Erba Carlo Spa Pharmaceutical preparations containing the history of A-amino carboxamide N-phenylalkyl are converted into such new compounds and their preparation
US5051403A (en) * 1989-11-22 1991-09-24 Neurex Corporation Method of treating ischemia-related neuronal damage
WO1993013128A1 (en) * 1991-12-30 1993-07-08 Neurex Corporation Methods of producing analgesia and enhancing opiate analgesia
GB9500691D0 (en) * 1995-01-13 1995-03-08 Smithkline Beecham Plc Compounds
GB9515412D0 (en) 1995-07-27 1995-09-27 Pharmacia Spa 2-(4-substituted)-benzylamino-2-methyl-propanamide derivatives
GB9518572D0 (en) 1995-09-12 1995-11-15 Smithkline Beecham Plc Compounds
US5845454A (en) * 1996-04-23 1998-12-08 Malizia; John T. Drop ceiling hanging system
WO1998035957A1 (en) 1997-02-14 1998-08-20 Bayer Corporation Amide derivatives as selective neuropeptide y receptor antagonists
WO1998054123A1 (en) * 1997-05-30 1998-12-03 Warner-Lambert Company Substituted peptidylamine calcium channel blockers
DE19740110A1 (de) 1997-09-12 1999-03-18 Boehringer Ingelheim Pharma Substituierte 1,2,3,4,5,6-Hexahydro-2,6-methano-3-benzazocin-10-ole, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
GB9727523D0 (en) 1997-12-31 1998-02-25 Pharmacia & Upjohn Spa Alpha-aminoamide derivatives useful as analgesic agents
US6458781B1 (en) * 1998-04-27 2002-10-01 David Thomas Connor Substituted diarylalkyl amides as calcium channel antagonists
US6011035A (en) * 1998-06-30 2000-01-04 Neuromed Technologies Inc. Calcium channel blockers
US6316440B1 (en) * 1998-07-30 2001-11-13 Warner-Lambert Company Reduced dipeptide analogues as calcium channel antagonists
AU7102700A (en) * 1999-09-22 2001-04-24 Ortho-Mcneil Pharmaceutical, Inc. Benzo-fused dithiepino[6,5-b]pyridines, and related compositions and methods
WO2001070748A1 (en) * 2000-03-23 2001-09-27 Ortho-Mcneil Pharmaceutical, Inc. THIEPINO [3,2-b] DIHYDROPYRIDINES AND RELATED COMPOSITIONS AND METHODS
AU4961001A (en) 2000-03-31 2001-10-15 Cocensys Inc Aminopyridines and their use as anticonvulsants and sodium channel blockers
US6521647B2 (en) * 2000-04-04 2003-02-18 Pfizer Inc. Treatment of renal disorders
SE0102858D0 (sv) 2001-08-27 2001-08-27 Astrazeneca Ab N-type calcium channel antagonists for the treatment of pain
DK1423168T3 (da) 2001-09-03 2006-05-15 Newron Pharm Spa Farmaceutisk præparat omfattende gabapentin eller en analog deraf og et alfa-aminoamid og dets analgetiske anvendelse
SI1458386T1 (sl) 2001-12-27 2007-08-31 Ortho Mcneil Pharm Inc Aroil pirol heteroeril in metanoli, uporabni za zdravljenje motnje centralnega živčnega sistema
EP1438956A1 (en) 2003-01-16 2004-07-21 Newron Pharmaceuticals S.p.A. Alpha-aminoamide derivatives useful as antimigraine agents
WO2004087125A1 (en) 2003-04-02 2004-10-14 Ionix Pharmaceuticals Limited Amino acid derivatives as inhibitors of mammalian sodium channels
AR044007A1 (es) * 2003-04-11 2005-08-24 Newron Pharmaceuticals Inc Metodos para el tratamiento de la enfermedad de parkinson
DK1658062T3 (da) * 2003-08-25 2010-05-31 Newron Pharm Spa Alfa-aminoamid-derivater anvendelige som anti-inflammatoriske midler
EP1557166A1 (en) * 2004-01-21 2005-07-27 Newron Pharmaceuticals S.p.A. Alpha-aminoamide derivatives useful in the treatment of lower urinary tract disorders
EP1588704A1 (en) 2004-04-22 2005-10-26 Newron Pharmaceuticals S.p.A. Alpha-aminoamide derivatives useful in the treatment of restless legs syndrome and addictive disorders
DK1809271T5 (da) 2004-09-10 2010-12-06 Newron Pharm Spa Anvendelse af (R)-(halogenbenzyloxy)benzylaminopropanamider som natrium- og/eller calciumkanalselektive modulatorer
EP1963280B1 (en) 2005-12-22 2015-10-28 Newron Pharmaceuticals S.p.A. 2-phenylethylamino derivatives as calcium and/or sodium channel modulators
EP1870097A1 (en) 2006-06-15 2007-12-26 Newron Pharmaceuticals S.p.A. Alpha-aminoamide derivatives useful in the treatment of cognitive disorders

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