JP2010529969A5 - - Google Patents

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Publication number
JP2010529969A5
JP2010529969A5 JP2010511510A JP2010511510A JP2010529969A5 JP 2010529969 A5 JP2010529969 A5 JP 2010529969A5 JP 2010511510 A JP2010511510 A JP 2010511510A JP 2010511510 A JP2010511510 A JP 2010511510A JP 2010529969 A5 JP2010529969 A5 JP 2010529969A5
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JP
Japan
Prior art keywords
ethylamino
alkyl
butoxyphenyl
compound
disorder
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2010511510A
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English (en)
Japanese (ja)
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JP5440496B2 (ja
JP2010529969A (ja
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Priority claimed from PCT/EP2008/003848 external-priority patent/WO2008151702A1/en
Publication of JP2010529969A publication Critical patent/JP2010529969A/ja
Publication of JP2010529969A5 publication Critical patent/JP2010529969A5/ja
Application granted granted Critical
Publication of JP5440496B2 publication Critical patent/JP5440496B2/ja
Active legal-status Critical Current
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JP2010511510A 2007-06-15 2008-05-14 置換２−［２−（フェニル）エチルアミノ］アルカンアミド誘導体ならびにナトリウムおよび／またはカルシウムチャネル調節剤としてのこれらの使用 Active JP5440496B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07011766 2007-06-15
EP07011766.8 2007-06-15
PCT/EP2008/003848 WO2008151702A1 (en) 2007-06-15 2008-05-14 Substituted 2- [2- (phenyl) ethylamino] alkaneamide derivatives and their use as sodium and/or calcium channel modulators

Publications (3)

Publication Number Publication Date
JP2010529969A JP2010529969A (ja) 2010-09-02
JP2010529969A5 true JP2010529969A5 (enExample) 2012-06-07
JP5440496B2 JP5440496B2 (ja) 2014-03-12

Family

ID=38658156

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010511510A Active JP5440496B2 (ja) 2007-06-15 2008-05-14 置換２−［２−（フェニル）エチルアミノ］アルカンアミド誘導体ならびにナトリウムおよび／またはカルシウムチャネル調節剤としてのこれらの使用

Country Status (27)

Country Link
US (8) US8519000B2 (enExample)
EP (1) EP2155663B1 (enExample)
JP (1) JP5440496B2 (enExample)
KR (1) KR101545124B1 (enExample)
CN (1) CN101687773B (enExample)
AR (1) AR068976A1 (enExample)
AU (1) AU2008261325B2 (enExample)
BR (1) BRPI0813363B8 (enExample)
CA (1) CA2689561C (enExample)
CY (1) CY1119787T1 (enExample)
DK (1) DK2155663T3 (enExample)
EA (1) EA018195B1 (enExample)
ES (1) ES2655704T3 (enExample)
HR (1) HRP20180324T8 (enExample)
HU (1) HUE038113T2 (enExample)
IL (1) IL202235A (enExample)
LT (1) LT2155663T (enExample)
MX (1) MX2009013119A (enExample)
NO (1) NO2155663T3 (enExample)
NZ (1) NZ581288A (enExample)
PL (1) PL2155663T3 (enExample)
PT (1) PT2155663T (enExample)
RS (1) RS56780B1 (enExample)
SI (1) SI2155663T1 (enExample)
TR (1) TR201802576T4 (enExample)
TW (1) TWI400071B (enExample)
WO (1) WO2008151702A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL173886A (en) * 2003-08-25 2012-09-24 Newron Pharm Spa Alpha-aminoamide derivatives for treating inflammatory disorders
JP5213265B2 (ja) * 2009-10-08 2013-06-19 花王株式会社 Ｌｏｘ−１発現調節剤の評価又は選択方法
RS55240B1 (sr) * 2011-06-27 2017-02-28 Newron Pharm Spa Fluorisani derivati arilalkilaminokarboksamida
CN103804341B (zh) * 2012-11-13 2018-04-10 中国人民解放军军事医学科学院毒物药物研究所 酰胺衍生物及其医药用途
CN104761531B (zh) * 2014-01-03 2017-12-01 中国人民解放军军事医学科学院毒物药物研究所 镇痛活性化合物及其医药用途
NZ742033A (en) * 2015-11-12 2022-11-25 Afasci Inc Ion channel inhibitory compounds, pharmaceutical formulations and uses
CN106316824B (zh) * 2016-08-18 2018-10-19 广州康瑞泰药业有限公司 一种合成2-氟环丙烷甲酸的新方法
WO2019205147A1 (zh) * 2018-04-28 2019-10-31 上海璃道医药科技有限公司 包含苯并含氧脂肪环结构的氨基乙酰胺类化合物及其用途
WO2020044309A1 (en) * 2018-08-30 2020-03-05 Sabic Global Technologies B.V. Aromatization catalyst with improved isomerization, process of making and using thereof
EP3725769A1 (en) 2019-04-17 2020-10-21 Newron Pharmaceuticals S.p.A. Process for the production of substituted 2-[2-(phenyl) ethylamino]alkaneamide derivatives
EP3725768A1 (en) 2019-04-17 2020-10-21 Newron Pharmaceuticals S.p.A. Process for the production of substituted 2-[2-(phenyl) ethylamino]alkaneamide derivatives
WO2024223671A1 (en) 2023-04-28 2024-10-31 Newron Pharmaceuticals S.P.A. Crystalline forms of evenamide

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GB586645A (en) 1944-07-19 1947-03-26 Burroughs Wellcome Co Improvements relating to the synthesis of amino acid derivatives and salts thereof
GB1254332A (en) * 1969-02-27 1971-11-17 Science Union & Cie Amino acids and their derivatives and processes for preparing them
IL94466A (en) * 1989-05-25 1995-01-24 Erba Carlo Spa Pharmaceutical preparations containing the history of A-amino carboxamide N-phenylalkyl are converted into such new compounds and their preparation
US5051403A (en) * 1989-11-22 1991-09-24 Neurex Corporation Method of treating ischemia-related neuronal damage
WO1993013128A1 (en) * 1991-12-30 1993-07-08 Neurex Corporation Methods of producing analgesia and enhancing opiate analgesia
GB9500691D0 (en) * 1995-01-13 1995-03-08 Smithkline Beecham Plc Compounds
GB9515412D0 (en) 1995-07-27 1995-09-27 Pharmacia Spa 2-(4-substituted)-benzylamino-2-methyl-propanamide derivatives
GB9518572D0 (en) 1995-09-12 1995-11-15 Smithkline Beecham Plc Compounds
US5845454A (en) * 1996-04-23 1998-12-08 Malizia; John T. Drop ceiling hanging system
EP0910565A1 (en) 1997-02-14 1999-04-28 Bayer Corporation Amide derivatives as selective neuropeptide y receptor antagonists
WO1998054123A1 (en) * 1997-05-30 1998-12-03 Warner-Lambert Company Substituted peptidylamine calcium channel blockers
DE19740110A1 (de) 1997-09-12 1999-03-18 Boehringer Ingelheim Pharma Substituierte 1,2,3,4,5,6-Hexahydro-2,6-methano-3-benzazocin-10-ole, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
GB9727523D0 (en) * 1997-12-31 1998-02-25 Pharmacia & Upjohn Spa Alpha-aminoamide derivatives useful as analgesic agents
AU3459999A (en) * 1998-04-27 1999-11-16 Warner-Lambert Company Substituted diarylalkyl amides as calcium channel antagonists
US6011035A (en) * 1998-06-30 2000-01-04 Neuromed Technologies Inc. Calcium channel blockers
AU4329499A (en) * 1998-07-30 2000-02-21 Warner-Lambert Company Reduced dipeptide analogues as calcium channel antagonists
US6472530B1 (en) * 1999-09-22 2002-10-29 Ortho-Mcneil Pharmaceutical, Inc. Benzo-fused dithiepino[6,5-b]pyridines, and related compositions and methods
JP2003528104A (ja) * 2000-03-23 2003-09-24 オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド チエピノ［３，２−ｂ］ジヒドロピリジンおよび関連組成物ならびに方法
CA2403991A1 (en) 2000-03-31 2001-10-11 Euro-Celtique S.A. Aminopyridines and their use as anticonvulsants and sodium channel blockers
US6521647B2 (en) * 2000-04-04 2003-02-18 Pfizer Inc. Treatment of renal disorders
SE0102858D0 (sv) 2001-08-27 2001-08-27 Astrazeneca Ab N-type calcium channel antagonists for the treatment of pain
EP1423168B1 (en) 2001-09-03 2006-02-08 Newron Pharmaceuticals S.p.A. Pharmaceutical composition comprising gabapentin or an analogue thereof and an alpha-aminoamide and its analgesic use
PT1458386E (pt) 2001-12-27 2007-06-04 Ortho Mcneil Pharm Inc ''aroilpirrole-heteroarilo e metanóis úteis para o tratamento de um distúrbio do sistema nervoso central''
EP1438956A1 (en) 2003-01-16 2004-07-21 Newron Pharmaceuticals S.p.A. Alpha-aminoamide derivatives useful as antimigraine agents
WO2004087125A1 (en) 2003-04-02 2004-10-14 Ionix Pharmaceuticals Limited Amino acid derivatives as inhibitors of mammalian sodium channels
AR044007A1 (es) * 2003-04-11 2005-08-24 Newron Pharmaceuticals Inc Metodos para el tratamiento de la enfermedad de parkinson
IL173886A (en) * 2003-08-25 2012-09-24 Newron Pharm Spa Alpha-aminoamide derivatives for treating inflammatory disorders
EP1557166A1 (en) 2004-01-21 2005-07-27 Newron Pharmaceuticals S.p.A. Alpha-aminoamide derivatives useful in the treatment of lower urinary tract disorders
EP1588704A1 (en) 2004-04-22 2005-10-26 Newron Pharmaceuticals S.p.A. Alpha-aminoamide derivatives useful in the treatment of restless legs syndrome and addictive disorders
DE602005021907D1 (de) 2004-09-10 2010-07-29 Newron Pharm Spa Verwendung von (r)-(halogenbenzyloxy)-benzylamino-propanamiden als natrium- und/oder calciumkanal-selektive modulatoren
EP1963280B1 (en) * 2005-12-22 2015-10-28 Newron Pharmaceuticals S.p.A. 2-phenylethylamino derivatives as calcium and/or sodium channel modulators
EP1870097A1 (en) 2006-06-15 2007-12-26 Newron Pharmaceuticals S.p.A. Alpha-aminoamide derivatives useful in the treatment of cognitive disorders

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