JP2010529969A5 - - Google Patents

Download PDF

Info

Publication number
JP2010529969A5
JP2010529969A5 JP2010511510A JP2010511510A JP2010529969A5 JP 2010529969 A5 JP2010529969 A5 JP 2010529969A5 JP 2010511510 A JP2010511510 A JP 2010511510A JP 2010511510 A JP2010511510 A JP 2010511510A JP 2010529969 A5 JP2010529969 A5 JP 2010529969A5
Authority
JP
Japan
Prior art keywords
ethylamino
alkyl
butoxyphenyl
compound
disorder
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2010511510A
Other languages
English (en)
Japanese (ja)
Other versions
JP2010529969A (ja
JP5440496B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2008/003848 external-priority patent/WO2008151702A1/en
Publication of JP2010529969A publication Critical patent/JP2010529969A/ja
Publication of JP2010529969A5 publication Critical patent/JP2010529969A5/ja
Application granted granted Critical
Publication of JP5440496B2 publication Critical patent/JP5440496B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2010511510A 2007-06-15 2008-05-14 置換２−［２−（フェニル）エチルアミノ］アルカンアミド誘導体ならびにナトリウムおよび／またはカルシウムチャネル調節剤としてのこれらの使用 Active JP5440496B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07011766 2007-06-15
EP07011766.8 2007-06-15
PCT/EP2008/003848 WO2008151702A1 (en) 2007-06-15 2008-05-14 Substituted 2- [2- (phenyl) ethylamino] alkaneamide derivatives and their use as sodium and/or calcium channel modulators

Publications (3)

Publication Number Publication Date
JP2010529969A JP2010529969A (ja) 2010-09-02
JP2010529969A5 true JP2010529969A5 (enExample) 2012-06-07
JP5440496B2 JP5440496B2 (ja) 2014-03-12

Family

ID=38658156

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010511510A Active JP5440496B2 (ja) 2007-06-15 2008-05-14 置換２−［２−（フェニル）エチルアミノ］アルカンアミド誘導体ならびにナトリウムおよび／またはカルシウムチャネル調節剤としてのこれらの使用

Country Status (27)

Country Link
US (8) US8519000B2 (enExample)
EP (1) EP2155663B1 (enExample)
JP (1) JP5440496B2 (enExample)
KR (1) KR101545124B1 (enExample)
CN (1) CN101687773B (enExample)
AR (1) AR068976A1 (enExample)
AU (1) AU2008261325B2 (enExample)
BR (1) BRPI0813363B8 (enExample)
CA (1) CA2689561C (enExample)
CY (1) CY1119787T1 (enExample)
DK (1) DK2155663T3 (enExample)
EA (1) EA018195B1 (enExample)
ES (1) ES2655704T3 (enExample)
HR (1) HRP20180324T8 (enExample)
HU (1) HUE038113T2 (enExample)
IL (1) IL202235A (enExample)
LT (1) LT2155663T (enExample)
MX (1) MX2009013119A (enExample)
NO (1) NO2155663T3 (enExample)
NZ (1) NZ581288A (enExample)
PL (1) PL2155663T3 (enExample)
PT (1) PT2155663T (enExample)
RS (1) RS56780B1 (enExample)
SI (1) SI2155663T1 (enExample)
TR (1) TR201802576T4 (enExample)
TW (1) TWI400071B (enExample)
WO (1) WO2008151702A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2339021T3 (es) * 2003-08-25 2010-05-14 Newron Pharmaceuticals S.P.A. Derivados de alfa-aminoamida utiles como agentes antiinflamatorios.
JP5213265B2 (ja) * 2009-10-08 2013-06-19 花王株式会社 Ｌｏｘ−１発現調節剤の評価又は選択方法
EA022973B1 (ru) 2011-06-27 2016-03-31 Ньюрон Фармасьютикалс С.П.А. Фторированные арилалкиламинокарбоксамидные производные
CN103804341B (zh) * 2012-11-13 2018-04-10 中国人民解放军军事医学科学院毒物药物研究所 酰胺衍生物及其医药用途
CN104761531B (zh) * 2014-01-03 2017-12-01 中国人民解放军军事医学科学院毒物药物研究所 镇痛活性化合物及其医药用途
JP6790094B2 (ja) * 2015-11-12 2020-11-25 エーエフエーエスシーアイ，インコーポレイテッド イオンチャネル阻害化合物、医薬製剤および使用
CN106316824B (zh) * 2016-08-18 2018-10-19 广州康瑞泰药业有限公司 一种合成2-氟环丙烷甲酸的新方法
CN112041296B (zh) * 2018-04-28 2023-12-29 上海璃道医药科技有限公司 包含苯并含氧脂肪环结构的氨基乙酰胺类化合物及其用途
US20210162380A1 (en) * 2018-08-30 2021-06-03 Sabic Global Technologies B.V. Aromatization catalyst with improved isomerization, process of making and using thereof
EP3725769A1 (en) 2019-04-17 2020-10-21 Newron Pharmaceuticals S.p.A. Process for the production of substituted 2-[2-(phenyl) ethylamino]alkaneamide derivatives
EP3725768A1 (en) 2019-04-17 2020-10-21 Newron Pharmaceuticals S.p.A. Process for the production of substituted 2-[2-(phenyl) ethylamino]alkaneamide derivatives
EP4699659A2 (en) 2023-04-28 2026-02-25 Newron Pharmaceuticals S.p.A. Crystalline forms of evenamide

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB586645A (en) * 1944-07-19 1947-03-26 Burroughs Wellcome Co Improvements relating to the synthesis of amino acid derivatives and salts thereof
GB1254332A (en) * 1969-02-27 1971-11-17 Science Union & Cie Amino acids and their derivatives and processes for preparing them
IL94466A (en) * 1989-05-25 1995-01-24 Erba Carlo Spa Pharmaceutical preparations containing the history of A-amino carboxamide N-phenylalkyl are converted into such new compounds and their preparation
US5051403A (en) 1989-11-22 1991-09-24 Neurex Corporation Method of treating ischemia-related neuronal damage
ATE165977T1 (de) 1991-12-30 1998-05-15 Neurex Corp Methoden zur erzeugung von analgesie und zur verstärkung von opiat-analgesie
GB9500691D0 (en) 1995-01-13 1995-03-08 Smithkline Beecham Plc Compounds
GB9515412D0 (en) 1995-07-27 1995-09-27 Pharmacia Spa 2-(4-substituted)-benzylamino-2-methyl-propanamide derivatives
GB9518572D0 (en) 1995-09-12 1995-11-15 Smithkline Beecham Plc Compounds
US5845454A (en) * 1996-04-23 1998-12-08 Malizia; John T. Drop ceiling hanging system
AU6144098A (en) 1997-02-14 1998-09-08 Bayer Corporation Amide derivatives as selective neuropeptide y receptor antagonists
WO1998054123A1 (en) 1997-05-30 1998-12-03 Warner-Lambert Company Substituted peptidylamine calcium channel blockers
DE19740110A1 (de) 1997-09-12 1999-03-18 Boehringer Ingelheim Pharma Substituierte 1,2,3,4,5,6-Hexahydro-2,6-methano-3-benzazocin-10-ole, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
GB9727523D0 (en) * 1997-12-31 1998-02-25 Pharmacia & Upjohn Spa Alpha-aminoamide derivatives useful as analgesic agents
WO1999055688A1 (en) 1998-04-27 1999-11-04 Warner-Lambert Company Substituted diarylalkyl amides as calcium channel antagonists
US6011035A (en) 1998-06-30 2000-01-04 Neuromed Technologies Inc. Calcium channel blockers
WO2000006559A1 (en) 1998-07-30 2000-02-10 Warner-Lambert Company Reduced dipeptide analogues as calcium channel antagonists
US6472530B1 (en) 1999-09-22 2002-10-29 Ortho-Mcneil Pharmaceutical, Inc. Benzo-fused dithiepino[6,5-b]pyridines, and related compositions and methods
JP2003528104A (ja) 2000-03-23 2003-09-24 オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド チエピノ［３，２−ｂ］ジヒドロピリジンおよび関連組成物ならびに方法
NZ521870A (en) 2000-03-31 2004-08-27 Euro Celtique S Aminopyridines and their use as anticonvulsants and sodium channel blockers
US6521647B2 (en) 2000-04-04 2003-02-18 Pfizer Inc. Treatment of renal disorders
SE0102858D0 (sv) 2001-08-27 2001-08-27 Astrazeneca Ab N-type calcium channel antagonists for the treatment of pain
SI1423168T1 (sl) 2001-09-03 2006-06-30 Newron Pharm Spa Farmacevtski sestavek, ki vsebuje gabapentin ali njegov analog in alfa-aminoamid, in njegova analgetska uporaba
ES2286328T3 (es) 2001-12-27 2007-12-01 Ortho-Mcneil Pharmaceutical, Inc. Aroilpirrolheteroaril y metanoles utiles para tratar transtornos del sistema nervioso central.
EP1438956A1 (en) 2003-01-16 2004-07-21 Newron Pharmaceuticals S.p.A. Alpha-aminoamide derivatives useful as antimigraine agents
WO2004087125A1 (en) * 2003-04-02 2004-10-14 Ionix Pharmaceuticals Limited Amino acid derivatives as inhibitors of mammalian sodium channels
AR044007A1 (es) * 2003-04-11 2005-08-24 Newron Pharmaceuticals Inc Metodos para el tratamiento de la enfermedad de parkinson
ES2339021T3 (es) * 2003-08-25 2010-05-14 Newron Pharmaceuticals S.P.A. Derivados de alfa-aminoamida utiles como agentes antiinflamatorios.
EP1557166A1 (en) 2004-01-21 2005-07-27 Newron Pharmaceuticals S.p.A. Alpha-aminoamide derivatives useful in the treatment of lower urinary tract disorders
EP1588704A1 (en) 2004-04-22 2005-10-26 Newron Pharmaceuticals S.p.A. Alpha-aminoamide derivatives useful in the treatment of restless legs syndrome and addictive disorders
US20080096965A1 (en) 2004-09-10 2008-04-24 Newron Pharmaceuticals S.P.A. (Halobenzyloxy) Benzylamino-Propanamides as Sodium and/or Calcium Channel Selective Modulators
EP1963280B1 (en) * 2005-12-22 2015-10-28 Newron Pharmaceuticals S.p.A. 2-phenylethylamino derivatives as calcium and/or sodium channel modulators
EP1870097A1 (en) 2006-06-15 2007-12-26 Newron Pharmaceuticals S.p.A. Alpha-aminoamide derivatives useful in the treatment of cognitive disorders

Similar Documents

Publication Publication Date Title
HRP20180324T1 (hr) Supstituirani derivati 2-[2-(fenil)etilamino]alkanamida i njihova upotreba kao modulatora natrijevih i/ili kalcijevih kanala
ES2620446T3 (es) Nuevo compuesto heterocíclico bicíclico
JP2009526831A5 (enExample)
JP2011510014A5 (enExample)
TW201329071A (zh) 麩胺酸酶的雜環抑制劑
JP2009510044A5 (enExample)
CA2682494A1 (en) Hexahydro-1h-4,7-methanoisoindole-1,3-dione compounds for treating psychiatric disorders
CN104010636B (zh) 三环化合物、包含它们的组合物及其用途
JP2008513496A5 (enExample)
JP2013507426A5 (enExample)
TW201607539A (zh) 加巴噴丁類似物和σ受體配體組合物
JP2025516005A5 (enExample)
JP2013522368A5 (enExample)
CN1192199A (zh) 2－(4－取代)－苄基氨基－2－甲基－丙酰胺衍生物
US20230051850A1 (en) Compositions and methods for reducing tactile dysfunction, anxiety, and social impairment
JP2005522439A5 (enExample)
EP1906955A2 (en) Use of thiazole derivatives and analogues in the treatment of cancer
CN111801013A (zh) 小分子核受体调节剂的酰胺前药
JP2015502371A5 (enExample)
ME02524B (me) Fluorisani derivati arilalkilaminokarboksamida
CN103781771B (zh) 苯并噻唑酮化合物
HRP20140326T1 (hr) Derivat aromatiäśnog 6-äślanog prstena koji sadrži dušik i farmaceutsko sredstvo koje sadrži taj derivat
JP2009521417A5 (enExample)
TWI441631B (zh) 有效於治療精神障礙之α－胺基醯胺衍生物
JP2007516292A5 (enExample)