JP2010524914A5 - - Google Patents
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- Publication number
- JP2010524914A5 JP2010524914A5 JP2010503606A JP2010503606A JP2010524914A5 JP 2010524914 A5 JP2010524914 A5 JP 2010524914A5 JP 2010503606 A JP2010503606 A JP 2010503606A JP 2010503606 A JP2010503606 A JP 2010503606A JP 2010524914 A5 JP2010524914 A5 JP 2010524914A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- heterocycloalkyl
- group
- cycloalkyl
- cancer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US91259707P | 2007-04-18 | 2007-04-18 | |
| US60/912,597 | 2007-04-18 | ||
| PCT/IB2008/000845 WO2008129380A1 (en) | 2007-04-18 | 2008-04-07 | Sulfonyl amide derivatives for the treatment of abnormal cell growth |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010524914A JP2010524914A (ja) | 2010-07-22 |
| JP2010524914A5 true JP2010524914A5 (OSRAM) | 2011-05-19 |
| JP4782239B2 JP4782239B2 (ja) | 2011-09-28 |
Family
ID=39646361
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010503606A Active JP4782239B2 (ja) | 2007-04-18 | 2008-04-07 | 異常細胞増殖治療のためのスルホニルアミド誘導体 |
Country Status (32)
| Country | Link |
|---|---|
| US (13) | US7928109B2 (OSRAM) |
| EP (1) | EP2146779B1 (OSRAM) |
| JP (1) | JP4782239B2 (OSRAM) |
| KR (1) | KR101132880B1 (OSRAM) |
| CN (2) | CN101678215B (OSRAM) |
| AP (1) | AP2009005010A0 (OSRAM) |
| AR (1) | AR066125A1 (OSRAM) |
| AU (1) | AU2008240359B2 (OSRAM) |
| BR (1) | BRPI0810411B8 (OSRAM) |
| CA (1) | CA2684447C (OSRAM) |
| CL (1) | CL2008001076A1 (OSRAM) |
| CO (1) | CO6260093A2 (OSRAM) |
| CU (1) | CU23813A3 (OSRAM) |
| DK (1) | DK2146779T3 (OSRAM) |
| DO (1) | DOP2009000248A (OSRAM) |
| EA (1) | EA016679B1 (OSRAM) |
| EC (1) | ECSP099694A (OSRAM) |
| ES (1) | ES2593486T3 (OSRAM) |
| GE (1) | GEP20125581B (OSRAM) |
| GT (1) | GT200900272A (OSRAM) |
| IL (3) | IL201468A (OSRAM) |
| MA (1) | MA31319B1 (OSRAM) |
| MX (1) | MX2009011090A (OSRAM) |
| NI (1) | NI200900190A (OSRAM) |
| NZ (1) | NZ580372A (OSRAM) |
| PA (1) | PA8777101A1 (OSRAM) |
| PE (1) | PE20090434A1 (OSRAM) |
| TN (1) | TN2009000428A1 (OSRAM) |
| TW (1) | TWI369205B (OSRAM) |
| UA (1) | UA97834C2 (OSRAM) |
| UY (1) | UY31026A1 (OSRAM) |
| WO (1) | WO2008129380A1 (OSRAM) |
Families Citing this family (71)
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|---|---|---|---|---|
| WO2008129380A1 (en) * | 2007-04-18 | 2008-10-30 | Pfizer Products Inc. | Sulfonyl amide derivatives for the treatment of abnormal cell growth |
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| WO2009122180A1 (en) * | 2008-04-02 | 2009-10-08 | Medical Research Council | Pyrimidine derivatives capable of inhibiting one or more kinases |
| CN102203080A (zh) * | 2008-09-03 | 2011-09-28 | 拜尔农作物科学股份公司 | 作为杀菌剂的杂环取代的苯胺基嘧啶 |
| UY32240A (es) * | 2008-11-14 | 2010-06-30 | Boeringer Ingelheim Kg | Nuevas 2,4-diaminopirimidinas, sus sales farmacéuticamente aceptables, composiciones conteniéndolas y aplicaciones. |
| JP2010111702A (ja) | 2009-02-16 | 2010-05-20 | Tetsuya Nishio | 複素環化合物、その製造法および用途 |
| CN101812016B (zh) * | 2009-02-23 | 2013-01-16 | 浙江海翔药业股份有限公司 | 一种制备依托昔布中间体-6-甲基烟酸及其酯的方法 |
| EP2261211A1 (en) * | 2009-05-20 | 2010-12-15 | Université de Lille 2 Droit et Santé | 1,4-dihydropyridine derivatives and their uses |
| TW201100441A (en) | 2009-06-01 | 2011-01-01 | Osi Pharm Inc | Amino pyrimidine anticancer compounds |
| BRPI1009637A2 (pt) | 2009-06-05 | 2019-04-30 | Cephalon, Inc | composto, composição e uso de um composto |
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| US20120244141A1 (en) | 2010-09-28 | 2012-09-27 | Boehringer Ingelheim International Gmbh | Stratification of cancer patients for susceptibility to therapy with PTK2 inhibitors |
| PL2646448T3 (pl) | 2010-11-29 | 2017-12-29 | OSI Pharmaceuticals, LLC | Makrocykliczne inhibitory kinazy |
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| US10779980B2 (en) | 2016-04-27 | 2020-09-22 | Synerz Medical, Inc. | Intragastric device for treating obesity |
| CN106279011A (zh) * | 2016-08-16 | 2017-01-04 | 成都百事兴科技实业有限公司 | 一种2,4‑二羟基‑6‑甲基烟酸乙酯的制备方法 |
| WO2019117813A1 (en) * | 2017-12-15 | 2019-06-20 | National University Of Singapore | Focal adhesion kinase targeted therapeutics for the treatment of glaucoma and fibrosis |
| JP2021517589A (ja) | 2018-03-12 | 2021-07-26 | アンセルム（アンスティチュート・ナシオナル・ドゥ・ラ・サンテ・エ・ドゥ・ラ・ルシェルシュ・メディカル） | 癌の治療のための化学免疫療法を増強するためのカロリー制限模倣物の使用 |
| US11891379B2 (en) | 2018-05-07 | 2024-02-06 | Hinova Pharmaceuticals Inc. | Deuterated Defactinib compound and use thereof |
| WO2020006724A1 (zh) * | 2018-07-05 | 2020-01-09 | 清华大学 | 一种靶向降解fak蛋白的化合物及其应用 |
| EP3856190A4 (en) * | 2018-09-27 | 2022-09-21 | Dana Farber Cancer Institute, Inc. | DEGRADATION OF FAK OR FAK AND ALK BY CONJUGATION OF FAK AND ALK INHIBITORS WITH E3-LIGASE LIGANDS AND METHODS OF USE |
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| WO2021047783A1 (en) | 2019-09-13 | 2021-03-18 | The Institute Of Cancer Research: Royal Cancer Hospital | Vs-6063 in combination with ch5126766 for the treatment of cancer |
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| CN112592318B (zh) * | 2020-12-12 | 2022-05-03 | 贵州医科大学 | 2-(4-甲氨酰基)苯胺基-4-氨基嘧啶衍生物及应用 |
| CN112624966B (zh) * | 2020-12-25 | 2022-12-23 | 杭州澳赛诺生物科技有限公司 | 一种2-氨甲基-4-甲基-5-吡啶羧酸的合成方法 |
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| CN114716385B (zh) * | 2022-04-08 | 2024-03-12 | 北京师范大学 | 靶向粘着斑激酶的化合物及制备方法和应用 |
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