JP2010508513A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2010508513A5 JP2010508513A5 JP2009534711A JP2009534711A JP2010508513A5 JP 2010508513 A5 JP2010508513 A5 JP 2010508513A5 JP 2009534711 A JP2009534711 A JP 2009534711A JP 2009534711 A JP2009534711 A JP 2009534711A JP 2010508513 A5 JP2010508513 A5 JP 2010508513A5
- Authority
- JP
- Japan
- Prior art keywords
- support
- ligand
- binding
- unsaturated
- assay
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003446 ligand Substances 0.000 claims 35
- 238000003556 assay Methods 0.000 claims 26
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 claims 24
- 239000012634 fragment Substances 0.000 claims 13
- 229960002685 biotin Drugs 0.000 claims 12
- 235000020958 biotin Nutrition 0.000 claims 12
- 239000011616 biotin Substances 0.000 claims 12
- 239000012491 analyte Substances 0.000 claims 11
- 229920001400 block copolymer Polymers 0.000 claims 10
- 238000000034 method Methods 0.000 claims 8
- 239000000203 mixture Substances 0.000 claims 7
- 239000007787 solid Substances 0.000 claims 7
- 108091003079 Bovine Serum Albumin Proteins 0.000 claims 6
- 108010058846 Ovalbumin Proteins 0.000 claims 6
- 229940098773 bovine serum albumin Drugs 0.000 claims 6
- 229940092253 ovalbumin Drugs 0.000 claims 6
- 230000002209 hydrophobic effect Effects 0.000 claims 5
- 108090001008 Avidin Proteins 0.000 claims 4
- 108010090804 Streptavidin Proteins 0.000 claims 4
- 108010087904 neutravidin Proteins 0.000 claims 4
- 102000004169 proteins and genes Human genes 0.000 claims 4
- 108090000623 proteins and genes Proteins 0.000 claims 4
- 102000037865 fusion proteins Human genes 0.000 claims 3
- 108020001507 fusion proteins Proteins 0.000 claims 3
- 239000011859 microparticle Substances 0.000 claims 3
- 108090000790 Enzymes Proteins 0.000 claims 2
- 102000004190 Enzymes Human genes 0.000 claims 2
- 108091034117 Oligonucleotide Proteins 0.000 claims 2
- JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 claims 2
- 102000040430 polynucleotide Human genes 0.000 claims 2
- 108091033319 polynucleotide Proteins 0.000 claims 2
- 239000002157 polynucleotide Substances 0.000 claims 2
- 108020003175 receptors Proteins 0.000 claims 2
- 102000029749 Microtubule Human genes 0.000 claims 1
- 108091022875 Microtubule Proteins 0.000 claims 1
- 239000000020 Nitrocellulose Substances 0.000 claims 1
- 239000004677 Nylon Substances 0.000 claims 1
- 229920003171 Poly (ethylene oxide) Polymers 0.000 claims 1
- 239000000427 antigen Substances 0.000 claims 1
- 108091007433 antigens Proteins 0.000 claims 1
- 102000036639 antigens Human genes 0.000 claims 1
- 239000011324 bead Substances 0.000 claims 1
- 108091006004 biotinylated proteins Proteins 0.000 claims 1
- 239000011248 coating agent Substances 0.000 claims 1
- 238000000576 coating method Methods 0.000 claims 1
- 230000008878 coupling Effects 0.000 claims 1
- 238000010168 coupling process Methods 0.000 claims 1
- 238000005859 coupling reaction Methods 0.000 claims 1
- 239000005556 hormone Substances 0.000 claims 1
- 229940088597 hormone Drugs 0.000 claims 1
- 108091008039 hormone receptors Proteins 0.000 claims 1
- 238000003018 immunoassay Methods 0.000 claims 1
- 239000000463 material Substances 0.000 claims 1
- 210000004688 microtubule Anatomy 0.000 claims 1
- 239000002105 nanoparticle Substances 0.000 claims 1
- 239000002071 nanotube Substances 0.000 claims 1
- 229920001220 nitrocellulos Polymers 0.000 claims 1
- 229920001778 nylon Polymers 0.000 claims 1
- 230000005298 paramagnetic effect Effects 0.000 claims 1
- 229920000642 polymer Polymers 0.000 claims 1
- 229920001451 polypropylene glycol Polymers 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
- 238000000159 protein binding assay Methods 0.000 claims 1
- 229920006395 saturated elastomer Polymers 0.000 claims 1
- 125000006850 spacer group Chemical group 0.000 claims 1
- 239000000758 substrate Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US86382006P | 2006-11-01 | 2006-11-01 | |
| US60/863,820 | 2006-11-01 | ||
| PCT/US2007/023033 WO2008057366A2 (en) | 2006-11-01 | 2007-11-01 | Binding surfaces for affinity assays |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010508513A JP2010508513A (ja) | 2010-03-18 |
| JP2010508513A5 true JP2010508513A5 (enExample) | 2011-12-15 |
| JP5224477B2 JP5224477B2 (ja) | 2013-07-03 |
Family
ID=39365040
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009534711A Expired - Fee Related JP5224477B2 (ja) | 2006-11-01 | 2007-11-01 | 親和性アッセイのための結合表面 |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US20080176340A1 (enExample) |
| EP (1) | EP2069790B1 (enExample) |
| JP (1) | JP5224477B2 (enExample) |
| KR (1) | KR101457716B1 (enExample) |
| CN (1) | CN101529251B (enExample) |
| AU (1) | AU2007317996B9 (enExample) |
| BR (1) | BRPI0718009B1 (enExample) |
| ES (1) | ES2537564T3 (enExample) |
| IL (1) | IL198490A (enExample) |
| MX (1) | MX2009004354A (enExample) |
| WO (1) | WO2008057366A2 (enExample) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050118727A1 (en) * | 2003-12-01 | 2005-06-02 | Carsten Schelp | Conjugates and their use in detection methods |
| WO2009005552A2 (en) * | 2007-03-29 | 2009-01-08 | Epitype Corporation | Methods and compositions for multivalent binding and methods for manufacture of rapid diagnostic tests |
| EP2199391B1 (en) | 2007-09-27 | 2015-11-11 | Japan Tobacco, Inc. | Factor involved in latent infection with herpesvirus, and use thereof |
| US7842475B2 (en) * | 2008-01-08 | 2010-11-30 | Siemens Healthcare Diagnostics Inc. | Stabilization of solid support assay reagents |
| US10539580B2 (en) * | 2008-04-29 | 2020-01-21 | Psychemedics Corporation | Solid phase multi-analyte assay |
| US20100051554A1 (en) * | 2008-08-28 | 2010-03-04 | Dong June Ahn | Molecular basket coated micro particles |
| CA2753873A1 (en) * | 2009-03-02 | 2010-09-10 | Japan Tobacco Inc. | Method for detecting substance in biological sample |
| EP2416158A4 (en) * | 2009-03-31 | 2012-05-30 | Japan Tobacco Inc | METHOD FOR DETECTING A SUBSTANCE IN A BIOLOGICAL SAMPLE |
| TW201040529A (en) * | 2009-03-31 | 2010-11-16 | Japan Tobacco Inc | Method for detecting antibody against SITH-1 in biological sample |
| WO2012044387A2 (en) * | 2010-07-06 | 2012-04-05 | T2 Biosystems, Inc. | Methods and compositions for detection of analytes |
| CN102207501A (zh) * | 2011-03-22 | 2011-10-05 | 沃克(天津)生物科技有限公司 | 生物素化牛血清白蛋白和链霉亲和素酶标反应板及其制备方法 |
| CN102331495B (zh) * | 2011-06-21 | 2013-12-25 | 沃克(天津)生物科技有限公司 | 食物过敏原检测试剂盒及其制备方法 |
| GB2497317A (en) * | 2011-12-06 | 2013-06-12 | Univ Dublin | System and method for the detection of analytes using rod-shaped nanoparticles |
| JP6231263B2 (ja) * | 2012-07-17 | 2017-11-15 | 株式会社島津製作所 | アフィニティ支持体及びそれを用いた物質の捕捉方法 |
| CN102809650B (zh) * | 2012-08-29 | 2015-02-11 | 沃克(天津)生物科技有限公司 | 生物素化牛丙种球蛋白-链霉亲和素酶标板及其制备方法 |
| US20140072959A1 (en) * | 2012-09-12 | 2014-03-13 | Force Diagnostics, Inc. | Rapid tests for insurance underwriting |
| US20160003819A1 (en) * | 2012-09-12 | 2016-01-07 | Force Diagnostics, Inc. | Rapid tests for insurance underwriting |
| WO2014176435A2 (en) | 2013-04-25 | 2014-10-30 | Bergo Vladislav B | Microarray compositions and methods of their use |
| CN103954771B (zh) * | 2014-04-28 | 2016-02-17 | 陕西师范大学 | 一种低成本捕获/释放及检测生物分子的方法 |
| AU2016250689B2 (en) | 2015-04-22 | 2021-07-08 | Berkeley Lights, Inc. | Microfluidic cell culture |
| KR102142901B1 (ko) * | 2015-10-16 | 2020-08-10 | 도요보 가부시키가이샤 | 면역 크로마토그래피 시험편 |
| US10799865B2 (en) | 2015-10-27 | 2020-10-13 | Berkeley Lights, Inc. | Microfluidic apparatus having an optimized electrowetting surface and related systems and methods |
| CN105467130A (zh) * | 2015-11-16 | 2016-04-06 | 北京中航赛维生物科技有限公司 | 一种使用磁微粒化学发光定量检测抗Sm抗体IgG的试剂盒及其制备方法和检测方法 |
| US10539578B2 (en) | 2015-12-28 | 2020-01-21 | Japan Tobacco Inc. | Method for diagnosing, treating, or preventing mood disorders |
| EP3423511B1 (en) | 2016-03-03 | 2021-04-21 | DSM IP Assets B.V. | Anti-fouling and specific binding surface, dispersions comprising particles having such surfaces, and methods of making these |
| WO2017170994A1 (ja) * | 2016-03-31 | 2017-10-05 | 古河電気工業株式会社 | 細胞収容チップ |
| US10948484B2 (en) | 2016-04-11 | 2021-03-16 | Veravas, Inc. | Sample depletion and enrichment to improve the quality of diagnostic test results |
| AU2017271673B2 (en) * | 2016-05-26 | 2022-04-14 | Berkeley Lights, Inc. | Covalently modified surfaces, kits, and methods of preparation and use |
| CN106057394B (zh) * | 2016-06-01 | 2018-02-13 | 深圳市瀚德标检生物工程有限公司 | 一种免疫磁性纳米微粒的制备方法 |
| AU2018327347A1 (en) | 2017-09-07 | 2020-03-19 | Adeptrix Corp. | Multiplexed bead arrays for proteomics |
| ES2953017T3 (es) * | 2018-04-03 | 2023-11-07 | Sanofi Sa | Dispositivo de tira de inmunoensayo de flujo lateral |
| CN119395003A (zh) * | 2018-07-30 | 2025-02-07 | 美国西门子医学诊断股份有限公司 | 用于进行生物素测定的试剂盒、微流体装置和方法 |
| WO2020061499A1 (en) | 2018-09-21 | 2020-03-26 | Berkeley Lights, Inc. | Functionalized well plate, methods of preparation and use thereof |
| WO2020070486A1 (en) | 2018-10-02 | 2020-04-09 | Osler Diagnostics Limited | Methods for immunoassays using electrochemical measurement |
| JP7054378B2 (ja) * | 2018-11-08 | 2022-04-13 | 富士レビオ株式会社 | Ｃａ１９－９測定方法及びｃａ１９－９測定キット、並びに、これらに用いる抗体固定化担体及びその製造方法 |
| CN109932305B (zh) * | 2019-03-27 | 2024-04-12 | 西安交通大学 | 一种测试非饱和颗粒材料粒间接触角的实验装置和方法 |
| DE102020001916B3 (de) * | 2020-03-24 | 2021-08-12 | Ava Lifescience Gmbh | Mikropartikel für bioanalytische Untersuchungen und Verfahren zum Herstellen eines solchen Mikropartikels |
| CN111679086B (zh) * | 2020-08-11 | 2020-11-13 | 苏州康和顺医疗技术有限公司 | 一种hbp的磁微粒化学发光法检测试剂盒及其制备方法 |
| CN113030461B (zh) * | 2021-03-12 | 2022-04-22 | 北京华科泰生物技术股份有限公司 | 含氨基或羧基基团物质标记的IgG抗体、人IgG磁微粒化学检测试剂盒及其制备方法 |
| CN114046749B (zh) * | 2021-10-26 | 2022-07-08 | 刘红霞 | 预制混凝土构件点状凹坑结合面粗糙度检测方法及系统 |
| CN116793795B (zh) * | 2023-08-29 | 2023-11-07 | 云南省农业科学院质量标准与检测技术研究所 | 一种农产品中农药残留检测装置 |
| CN118425131A (zh) * | 2024-05-07 | 2024-08-02 | 巴迪泰（广西）生物科技有限公司 | 一种降低全血检测中血细胞干扰的方法 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5847258A (ja) * | 1981-09-01 | 1983-03-18 | イ−・アイ・デユポン・ド・ネモア−ス・アンド・コンパニ− | 光散乱イムノアツセイ用粒子試薬 |
| US4480042A (en) | 1981-10-28 | 1984-10-30 | E. I. Du Pont De Nemours And Company | Covalently bonded high refractive index particle reagents and their use in light scattering immunoassays |
| JPS61252215A (ja) * | 1984-05-07 | 1986-11-10 | エイチ・エス・シ−・リサ−チ・デイベロツプメント・コ−ポレイシヨン | アミノ基を有する分子の固定化用物質、その製造方法およびその使用方法 |
| DE3532626A1 (de) * | 1985-09-12 | 1987-03-19 | Boehringer Mannheim Gmbh | Verfahren zur bestimmung eines partners einer immunreaktion |
| JP2619549B2 (ja) * | 1989-06-29 | 1997-06-11 | 日本商事株式会社 | 抗原の定量法およびそれに用いる固相 |
| DE4219159A1 (de) * | 1992-06-11 | 1993-12-16 | Boehringer Mannheim Gmbh | Selbst assemblierende Monoschicht mit kurzkettigen Linkern |
| ATE209782T1 (de) * | 1993-05-18 | 2001-12-15 | Univ Utah Res Found | Vorrichtung und verfahren fuer homogene multianalyt-immuno-assays |
| US5516703A (en) * | 1993-08-20 | 1996-05-14 | The University Of Utah | Coating of hydrophobic surfaces to render them protein resistant while permitting covalent attachment of specific ligands |
| US6284503B1 (en) * | 1993-08-20 | 2001-09-04 | University Of Utah Research Foundation | Composition and method for regulating the adhesion of cells and biomolecules to hydrophobic surfaces |
| DE19724787A1 (de) * | 1997-06-06 | 1998-12-10 | Biotez Berlin Buch Gmbh Bioche | Streptavidin/Avidin beschichtete Oberflächen |
| US6372448B1 (en) * | 1998-12-30 | 2002-04-16 | Millennium Pharmaceuticals, Inc. | Use of ylqF, yqeG, yybQ, and ysxC, essential bacterial genes and polypeptides |
| US6638728B1 (en) * | 2000-06-16 | 2003-10-28 | Pierce Biotechnology, Inc. | Coated surfaces with high capacity for capturing target molecules |
| US20040072262A1 (en) | 2002-10-11 | 2004-04-15 | Montero-Julian Felix A. | Methods and systems for detecting MHC class I binding peptides |
| JP4022816B2 (ja) * | 2002-10-28 | 2007-12-19 | 東洋紡績株式会社 | 蛋白質もしくはペプチドのＫｉｎｅｔｉｃｓ解析方法および解析用基板 |
| US6821744B2 (en) * | 2002-10-29 | 2004-11-23 | Roche Diagnostics Operations, Inc. | Method, assay, and kit for quantifying HIV protease inhibitors |
| DE10310261A1 (de) * | 2003-03-05 | 2004-09-23 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Identifizierung von Antigen-Epitopen |
| FR2855613B1 (fr) * | 2003-05-26 | 2005-08-19 | Biocytex | Procede de detection et de quantification multiplex d'analytes dans un echantillon a l'aide de microspheres |
| EP1648919B1 (en) | 2003-07-22 | 2010-11-17 | Beckman Coulter, Inc. | Methods for detecting activation of t-cells by mhc binding peptides |
| ES2322061T3 (es) | 2003-07-28 | 2009-06-16 | Jsr Corporation | Superficie de material de base que se inhibe en adsorcion no especifica. |
| JP2005069891A (ja) * | 2003-08-25 | 2005-03-17 | Sekisui Chem Co Ltd | 測定試薬用担体粒子及び測定試薬 |
| AU2004276761B2 (en) * | 2003-09-22 | 2009-12-24 | Bioarray Solutions, Ltd. | Surface immobilized polyelectrolyte with multiple functional groups capable of covalently bonding to biomolecules |
| JP4427312B2 (ja) * | 2003-12-19 | 2010-03-03 | 三菱化学メディエンス株式会社 | 分析用キット |
| JP3774460B2 (ja) * | 2004-01-30 | 2006-05-17 | 独立行政法人科学技術振興機構 | 物質の検出方法 |
-
2007
- 2007-11-01 JP JP2009534711A patent/JP5224477B2/ja not_active Expired - Fee Related
- 2007-11-01 US US11/979,331 patent/US20080176340A1/en not_active Abandoned
- 2007-11-01 AU AU2007317996A patent/AU2007317996B9/en not_active Ceased
- 2007-11-01 CN CN200780040215.4A patent/CN101529251B/zh not_active Expired - Fee Related
- 2007-11-01 KR KR1020097008989A patent/KR101457716B1/ko not_active Expired - Fee Related
- 2007-11-01 BR BRPI0718009A patent/BRPI0718009B1/pt not_active IP Right Cessation
- 2007-11-01 MX MX2009004354A patent/MX2009004354A/es active IP Right Grant
- 2007-11-01 WO PCT/US2007/023033 patent/WO2008057366A2/en not_active Ceased
- 2007-11-01 ES ES07861621.6T patent/ES2537564T3/es active Active
- 2007-11-01 EP EP07861621.6A patent/EP2069790B1/en not_active Not-in-force
-
2009
- 2009-04-30 IL IL198490A patent/IL198490A/en active IP Right Grant
-
2011
- 2011-09-23 US US13/242,699 patent/US8518714B2/en not_active Expired - Fee Related
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2010508513A5 (enExample) | ||
| Liu et al. | Oriented immobilization of proteins on solid supports for use in biosensors and biochips: a review | |
| CN101529251B (zh) | 用于亲合分析的结合性表面 | |
| US9297800B2 (en) | Biomaterial construct, its producing method, biomaterial support, target material purifying method, affinity chromatography container, separation chip, analyzing method and analyzing separator for target material, biomaterial complex, and its support, sensor chip, solid support with biomaterial fixed thereon | |
| JPWO2022103887A5 (enExample) | ||
| JP2003526786A5 (enExample) | ||
| JP2013055939A (ja) | 脂質膜への付着に関係するオリゴヌクレオチド | |
| US20060257919A1 (en) | Polymer-coated substrates for binding biological molecules | |
| JP2004525345A (ja) | 磁力によって支持体に固定化されている生物学的又は化学的プローブの固定マイクロアレイ | |
| JP2002522748A5 (enExample) | ||
| WO2013001447A1 (en) | Molecular architecture on magnetic particles for affinity assays with low non-specific binding | |
| JP2004510160A5 (enExample) | ||
| Wen et al. | Specific antibody immobilization with biotin-poly (l-lysine)-g-poly (ethylene glycol) and protein A on microfluidic chips | |
| US20060281076A1 (en) | Substrate functionalization method for high sensitivity applications | |
| JP2005514583A5 (enExample) | ||
| Zhou et al. | Protein microarrays on hybrid polymeric thin films prepared by self‐assembly of polyelectrolytes for multiple‐protein immunoassays | |
| JP2005514583A6 (ja) | 大容量アッセイ・プラットフォーム | |
| JP4197279B2 (ja) | 生体由来物検出用基板及びその製造方法 | |
| Liu et al. | Optimization of printing buffer for protein microarrays based on aldehyde-modified glass slides | |
| JP5148818B2 (ja) | 新規固相担体及びその利用 | |
| KR101293666B1 (ko) | 단백질 나노입자를 이용한 3차원 나노구조체 | |
| JP2005528583A (ja) | 接着方法 | |
| Hao et al. | Molecular conformations of DNA targets captured by model nanoarrays | |
| JP2007279028A (ja) | 孔を有する生体物質構造体及びその製造方法、並びに、それを用いた生体物質担持体、対象物質の精製方法、アフィニティークロマトグラフィー用容器、分離用チップ、対象物質の解析方法、対象物質の解析用分離装置、及びセンサーチップ | |
| CN1629636A (zh) | 检测生物聚合物的方法；生物芯片；固定抗体的方法；以及在其上固定抗体的基质 |