JP2004510160A5 - - Google Patents

Download PDF

Info

Publication number
JP2004510160A5
JP2004510160A5 JP2002530643A JP2002530643A JP2004510160A5 JP 2004510160 A5 JP2004510160 A5 JP 2004510160A5 JP 2002530643 A JP2002530643 A JP 2002530643A JP 2002530643 A JP2002530643 A JP 2002530643A JP 2004510160 A5 JP2004510160 A5 JP 2004510160A5
Authority
JP
Japan
Prior art keywords
linker
reactive functional
functional group
complex
integer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2002530643A
Other languages
English (en)
Japanese (ja)
Other versions
JP2004510160A (ja
JP3647845B2 (ja
Filing date
Publication date
Priority claimed from DE10048417A external-priority patent/DE10048417A1/de
Application filed filed Critical
Publication of JP2004510160A publication Critical patent/JP2004510160A/ja
Publication of JP2004510160A5 publication Critical patent/JP2004510160A5/ja
Application granted granted Critical
Publication of JP3647845B2 publication Critical patent/JP3647845B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

JP2002530643A 2000-09-29 2001-09-26 分枝リンカーを有する化合物 Expired - Lifetime JP3647845B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10048417A DE10048417A1 (de) 2000-09-29 2000-09-29 Verbindungen mit verzweigtem Linker
PCT/EP2001/011118 WO2002027315A2 (en) 2000-09-29 2001-09-26 Compounds with a branched linker

Publications (3)

Publication Number Publication Date
JP2004510160A JP2004510160A (ja) 2004-04-02
JP2004510160A5 true JP2004510160A5 (enExample) 2005-03-03
JP3647845B2 JP3647845B2 (ja) 2005-05-18

Family

ID=7658168

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2002530643A Expired - Lifetime JP3647845B2 (ja) 2000-09-29 2001-09-26 分枝リンカーを有する化合物

Country Status (10)

Country Link
US (2) US20040086943A1 (enExample)
EP (1) EP1327146B1 (enExample)
JP (1) JP3647845B2 (enExample)
AT (1) ATE304709T1 (enExample)
AU (1) AU2002215904A1 (enExample)
CA (1) CA2423916C (enExample)
DE (2) DE10048417A1 (enExample)
DK (1) DK1327146T3 (enExample)
ES (1) ES2248405T3 (enExample)
WO (1) WO2002027315A2 (enExample)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100361933B1 (ko) 1993-09-08 2003-02-14 라 졸라 파마슈티칼 컴파니 화학적으로정의된비중합성결합가플랫폼분자및그것의콘주게이트
US6858210B1 (en) 1998-06-09 2005-02-22 La Jolla Pharmaceutical Co. Therapeutic and diagnostic domain 1 β2GPI polypeptides and methods of using same
CA2414076A1 (en) 2000-06-08 2001-12-13 La Jolla Pharmaceutical Company Multivalent platform molecules comprising high molecular weight polyethylene oxide
US20100056762A1 (en) 2001-05-11 2010-03-04 Old Lloyd J Specific binding proteins and uses thereof
DK1392359T4 (da) 2001-05-11 2013-06-10 Ludwig Inst For Cancer Res Ltd Specifikke bindingsproteiner og deres anvendelser.
KR100985457B1 (ko) 2001-06-21 2010-10-06 다이나박스 테크놀로지 코퍼레이션 키메라 면역조절 화합물 및 그것들의 사용 방법
DE10227599B4 (de) * 2002-06-20 2005-04-28 Proteome Factory Ag Verfahren und Reagenz zur spezifischen Identifizierung und Quantifizierung von einem oder mehreren Proteinen in einer Probe
WO2004016786A2 (de) * 2002-07-19 2004-02-26 Mologen Ag Dna-expressionskonstrukt zur multiplen genexpression
GB0329825D0 (en) * 2003-12-23 2004-01-28 Celltech R&D Ltd Biological products
ES2349649T3 (es) * 2004-07-30 2011-01-07 Advanced Life Science Institute, Inc. Complejo sonda.
EP1951870B1 (de) 2005-11-25 2013-04-24 Mologen AG Dna-konstrukte zur spezifischen hemmung der genexpression durch rna-interferenz
GB0607479D0 (en) * 2006-04-13 2006-05-24 Johnson Matthey Plc Adhesion promoting compound
US9090693B2 (en) 2007-01-25 2015-07-28 Dana-Farber Cancer Institute Use of anti-EGFR antibodies in treatment of EGFR mutant mediated disease
JP5618549B2 (ja) 2007-03-15 2014-11-05 ルードヴィッヒ インスティテュート フォー キャンサーリサーチ リミテッド Ｅｇｆｒ抗体及びｓｒｃ阻害剤を用いる治療方法及び関連製剤
JP5532486B2 (ja) 2007-08-14 2014-06-25 ルードヴィッヒ インスティテュート フォー キャンサー リサーチ Ｅｇｆ受容体を標的とするモノクローナル抗体１７５ならびにその誘導体および用途
WO2010008519A2 (en) * 2008-07-14 2010-01-21 Andrew Metters In vitro diagnostic markers comprising carbon nanoparticles and kits
CN103588801A (zh) * 2013-12-02 2014-02-19 天津大港油田圣达科技有限公司 一种微量元素井间示踪剂的使用方法
AU2019403552A1 (en) * 2018-12-21 2021-06-17 Seagen Inc. ADCs with thiol multiplex linkers
CN113454455B (zh) 2018-12-28 2024-04-30 雅培制药有限公司 微粒上的单分子的直接检测
US12540893B2 (en) 2019-12-18 2026-02-03 Standard Biotools Canada Inc. Mass cytometry reagents and methods for signal amplification
WO2022136234A1 (en) * 2020-12-22 2022-06-30 F. Hoffmann-La Roche Ag Method for detecting an analyte of interest in a sample
CN119775256B (zh) * 2024-12-31 2025-09-19 英科新创（苏州）生物科技有限公司 吖啶磺酰胺衍生物、制备方法、其应用及试剂盒

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5075447A (en) * 1984-09-17 1991-12-24 Hoffmann-La Roche Inc. Ruthenium complexes useful as carriers for immunologically active materials
DK365785A (da) * 1984-09-17 1986-03-18 Hoffmann La Roche Metalcomplexer
FR2579224B1 (fr) * 1985-03-25 1987-05-22 Genetica Procede de preparation microbiologique de la serum-albumine humaine
US5750409A (en) * 1991-11-18 1998-05-12 Boehringer Mannheim Gmbh Pentacyclic compounds and their use as absorption or fluorescent dyes
GB9215780D0 (en) * 1992-07-24 1992-09-09 Univ London Pharmacy Peptide compounds
DE4310141A1 (de) * 1993-03-29 1994-10-06 Boehringer Mannheim Gmbh Homobidentale trifunktionelle Linker
GB9407812D0 (en) * 1994-04-20 1994-06-15 Nycomed Salutar Inc Compounds
WO1996003652A1 (de) * 1994-07-25 1996-02-08 Boehringer Mannheim Gmbh Bestimmung von spezifischem immunglobulin unter verwendung multipler antigene
ES2148540T3 (es) * 1994-07-25 2000-10-16 Roche Diagnostics Gmbh Complejos metalicos con enlazador cargado.
DE59507438D1 (de) * 1994-07-25 2000-01-20 Roche Diagnostics Gmbh Hydrophile metallkomplexe
WO1996003651A1 (de) * 1994-07-25 1996-02-08 Boehringer Mannheim Gmbh Metallchelat-markierte peptide
US5804371A (en) * 1994-07-25 1998-09-08 Boehringer Mannheim Gmbh Hapten-labelled peptides
US5718915A (en) * 1994-10-31 1998-02-17 Burstein Laboratories, Inc. Antiviral liposome having coupled target-binding moiety and hydrolytic enzyme
DE19519973A1 (de) * 1995-05-31 1996-12-05 Boehringer Mannheim Gmbh Entstörungsreagenz für die Bestimmung eines Analyten mit einem lumineszenzfähigen Metallkomplex
US5714360A (en) * 1995-11-03 1998-02-03 Bsi Corporation Photoactivatable water soluble cross-linking agents containing an onium group
EP0941120A4 (en) * 1996-11-05 2004-08-18 Bristol Myers Squibb Co BRANCHED PEPTIDLINKERS
CA2323048C (en) * 1998-03-12 2006-10-10 Shearwater Polymers, Inc. Poly(ethylene glycol) derivatives with proximal reactive groups
DE19811582A1 (de) * 1998-03-17 1999-09-23 Roche Diagnostics Gmbh Stabilisierung und Verstärkung von Elektrochemilumineszenz-Signalen
US6153655A (en) * 1998-04-17 2000-11-28 Enzon, Inc. Terminally-branched polymeric linkers and polymeric conjugates containing the same
US6708967B1 (en) * 1998-09-29 2004-03-23 Hewlett-Packard Development Company, L.P. Method and apparatus for making booklets
GB2413081A (en) * 2004-04-13 2005-10-19 Sca Hygiene Prod Ab Absorbant article with folded side flap portions and method of manufacture

Similar Documents

Publication Publication Date Title
US6670199B2 (en) Composition and method for regulating the adhesion of cells and biomolecules to hydrophobic surfaces
EP0406473B1 (en) Ion capture reagents and methods for performing binding assays
JP2002513556A5 (enExample)
AU3150400A (en) Immobilization of molecules on surfaces via polymer brushes
CN101363870A (zh) 生物传感芯片及其制备方法
AU654833B2 (en) The use of pairs of peptides with extremely high specific affinity for one another in the area of in vitro diagnosis
JP2004512258A5 (enExample)
WO1999017120A1 (en) Preparing conjugates using polyethylene glycol linkers
JPH10509731A (ja) ホスファターゼ活性化架橋剤、結合剤及び還元剤とその使用方法、並びにホスファターゼ活性化架橋剤及び結合剤を含む試薬
CN1300581C (zh) Sars病毒抗体检测方法及快速诊断试剂盒和制备方法
US5518882A (en) Immunological methods of component selection and recovery
JP2002535016A5 (enExample)
WO1991006311A1 (en) Anti-viral material
EP1176423A1 (en) Surface-attached polyfunctional polymer networks for sensor chips
JPH11124396A (ja) 樹状ポリペプチド
JP2824516B2 (ja) 免疫学的に検出可能な物質の測定法、反応容器及びイムノアッセイ原理による方法における種々のパラメーターの測定法
WO2003104424A2 (en) Novel molecular conjugates for signal amplification
CN110501495A (zh) 活化氨基固相颗粒与免疫氨基固相颗粒及其制备方法和应用及试剂盒
JPH03255959A (ja) ポリマー
JP2509840B2 (ja) 免疫測定法及び免疫測定用試薬キット
JPH08133990A (ja) 反応性マイクロスフェアー
JP2547149B2 (ja) 免疫測定法及び免疫測定用試薬キット
JP2003532420A5 (enExample)
JP2000281645A5 (enExample)
EP0569086A2 (en) Method and kit for attaching compounds to carboxylated substrates using uronium salt