JP2004510160A5 - - Google Patents

Download PDF

Info

Publication number
JP2004510160A5
JP2004510160A5 JP2002530643A JP2002530643A JP2004510160A5 JP 2004510160 A5 JP2004510160 A5 JP 2004510160A5 JP 2002530643 A JP2002530643 A JP 2002530643A JP 2002530643 A JP2002530643 A JP 2002530643A JP 2004510160 A5 JP2004510160 A5 JP 2004510160A5
Authority
JP
Japan
Prior art keywords
linker
reactive functional
functional group
complex
integer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2002530643A
Other languages
English (en)
Japanese (ja)
Other versions
JP2004510160A (ja
JP3647845B2 (ja
Filing date
Publication date
Priority claimed from DE10048417A external-priority patent/DE10048417A1/de
Application filed filed Critical
Publication of JP2004510160A publication Critical patent/JP2004510160A/ja
Publication of JP2004510160A5 publication Critical patent/JP2004510160A5/ja
Application granted granted Critical
Publication of JP3647845B2 publication Critical patent/JP3647845B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

JP2002530643A 2000-09-29 2001-09-26 分枝リンカーを有する化合物 Expired - Lifetime JP3647845B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10048417A DE10048417A1 (de) 2000-09-29 2000-09-29 Verbindungen mit verzweigtem Linker
PCT/EP2001/011118 WO2002027315A2 (en) 2000-09-29 2001-09-26 Compounds with a branched linker

Publications (3)

Publication Number Publication Date
JP2004510160A JP2004510160A (ja) 2004-04-02
JP2004510160A5 true JP2004510160A5 (enExample) 2005-03-03
JP3647845B2 JP3647845B2 (ja) 2005-05-18

Family

ID=7658168

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2002530643A Expired - Lifetime JP3647845B2 (ja) 2000-09-29 2001-09-26 分枝リンカーを有する化合物

Country Status (10)

Country Link
US (2) US20040086943A1 (enExample)
EP (1) EP1327146B1 (enExample)
JP (1) JP3647845B2 (enExample)
AT (1) ATE304709T1 (enExample)
AU (1) AU2002215904A1 (enExample)
CA (1) CA2423916C (enExample)
DE (2) DE10048417A1 (enExample)
DK (1) DK1327146T3 (enExample)
ES (1) ES2248405T3 (enExample)
WO (1) WO2002027315A2 (enExample)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100361933B1 (ko) 1993-09-08 2003-02-14 라 졸라 파마슈티칼 컴파니 화학적으로정의된비중합성결합가플랫폼분자및그것의콘주게이트
US6858210B1 (en) 1998-06-09 2005-02-22 La Jolla Pharmaceutical Co. Therapeutic and diagnostic domain 1 β2GPI polypeptides and methods of using same
US6951939B2 (en) 2000-06-08 2005-10-04 La Jolla Pharmaceutical Company Multivalent platform molecules comprising high molecular weight polyethylene oxide
PT1392359E (pt) 2001-05-11 2010-01-27 Ludwig Inst For Cancer Res Ltd Proteínas de ligação específica e suas utilizações
US20100056762A1 (en) 2001-05-11 2010-03-04 Old Lloyd J Specific binding proteins and uses thereof
AU2002345847B2 (en) 2001-06-21 2008-05-29 Dynavax Technologies Corporation Chimeric immunomodulatory compounds and methods of using the same
DE10227599B4 (de) * 2002-06-20 2005-04-28 Proteome Factory Ag Verfahren und Reagenz zur spezifischen Identifizierung und Quantifizierung von einem oder mehreren Proteinen in einer Probe
DE50306394D1 (de) * 2002-07-19 2007-03-15 Mologen Ag Dna-expressionskonstrukt zur multiplen genexpression
GB0329825D0 (en) * 2003-12-23 2004-01-28 Celltech R&D Ltd Biological products
DE602005023624D1 (de) * 2004-07-30 2010-10-28 Advanced Life Science Inst Inc Sondenkomplex
AU2006317222B2 (en) 2005-11-25 2011-06-30 Mologen Ag DNA constructs for specific inhibition of gene expression by RNA interference
GB0607479D0 (en) * 2006-04-13 2006-05-24 Johnson Matthey Plc Adhesion promoting compound
WO2008091701A2 (en) 2007-01-25 2008-07-31 Dana-Farber Cancer Institute Use of anti-egfr antibodies in treatment of egfr mutant mediated disease
CA2680854C (en) 2007-03-15 2017-02-14 Ludwig Institute For Cancer Research Treatment method using egfr antibodies and src inhibitors and related formulations
MX2010001757A (es) 2007-08-14 2010-09-14 Ludwig Inst Cancer Res Anticuerpo monoclonal 175 que activa el receptor egf y derivados y usos del mismo.
EP2318051A4 (en) * 2008-07-14 2012-12-26 Andrew Metters IN VITRO DIAGNOSTIC MARKERS COMPRISING CARBON NANOPARTICLES AND KITS
CN103588801A (zh) * 2013-12-02 2014-02-19 天津大港油田圣达科技有限公司 一种微量元素井间示踪剂的使用方法
JP2022514348A (ja) * 2018-12-21 2022-02-10 シージェン インコーポレイテッド チオール多重リンカーを有するadc
WO2020140071A1 (en) 2018-12-28 2020-07-02 Abbott Laboratories Direct detection of single molecules on microparticles
CA3162257A1 (en) * 2019-12-18 2021-06-24 Bedilu ALLO Mass cytometry reagents and methods for signal amplification
CN119775256B (zh) * 2024-12-31 2025-09-19 英科新创(苏州)生物科技有限公司 吖啶磺酰胺衍生物、制备方法、其应用及试剂盒

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5075447A (en) * 1984-09-17 1991-12-24 Hoffmann-La Roche Inc. Ruthenium complexes useful as carriers for immunologically active materials
DK365785A (da) * 1984-09-17 1986-03-18 Hoffmann La Roche Metalcomplexer
FR2579224B1 (fr) * 1985-03-25 1987-05-22 Genetica Procede de preparation microbiologique de la serum-albumine humaine
US5750409A (en) * 1991-11-18 1998-05-12 Boehringer Mannheim Gmbh Pentacyclic compounds and their use as absorption or fluorescent dyes
GB9215780D0 (en) * 1992-07-24 1992-09-09 Univ London Pharmacy Peptide compounds
DE4310141A1 (de) * 1993-03-29 1994-10-06 Boehringer Mannheim Gmbh Homobidentale trifunktionelle Linker
GB9407812D0 (en) * 1994-04-20 1994-06-15 Nycomed Salutar Inc Compounds
CN1148578C (zh) * 1994-07-25 2004-05-05 罗切诊断学有限公司 免疫测定特异抗体的方法、所用试剂、抗原及其用途
CN1075817C (zh) * 1994-07-25 2001-12-05 罗切诊断学有限公司 亲水的金属络合物
ES2171190T3 (es) * 1994-07-25 2002-09-01 Roche Diagnostics Gmbh Peptidos marcados con haptenos.
US6531572B1 (en) * 1994-07-25 2003-03-11 Roche Diagnostics Gmbh Metal chelate-labelled peptides
US5958783A (en) * 1994-07-25 1999-09-28 Roche Diagnostics Gmbh Metal complexes with a charged linker
US5718915A (en) * 1994-10-31 1998-02-17 Burstein Laboratories, Inc. Antiviral liposome having coupled target-binding moiety and hydrolytic enzyme
DE19519973A1 (de) * 1995-05-31 1996-12-05 Boehringer Mannheim Gmbh Entstörungsreagenz für die Bestimmung eines Analyten mit einem lumineszenzfähigen Metallkomplex
US5714360A (en) * 1995-11-03 1998-02-03 Bsi Corporation Photoactivatable water soluble cross-linking agents containing an onium group
WO1998019705A1 (en) * 1996-11-05 1998-05-14 Bristol-Myers Squibb Company Branched peptide linkers
ATE399809T1 (de) * 1998-03-12 2008-07-15 Nektar Therapeutics Al Corp Verfahren zur herstellung von polymerkonjugaten
DE19811582A1 (de) * 1998-03-17 1999-09-23 Roche Diagnostics Gmbh Stabilisierung und Verstärkung von Elektrochemilumineszenz-Signalen
US6153655A (en) * 1998-04-17 2000-11-28 Enzon, Inc. Terminally-branched polymeric linkers and polymeric conjugates containing the same
CN1178800C (zh) * 1998-09-29 2004-12-08 惠普公司 加工小册子的方法和设备
GB2413081A (en) * 2004-04-13 2005-10-19 Sca Hygiene Prod Ab Absorbant article with folded side flap portions and method of manufacture

Similar Documents

Publication Publication Date Title
JP2004510160A5 (enExample)
US6670199B2 (en) Composition and method for regulating the adhesion of cells and biomolecules to hydrophobic surfaces
EP0406473B1 (en) Ion capture reagents and methods for performing binding assays
JP2002513556A5 (enExample)
AU3150400A (en) Immobilization of molecules on surfaces via polymer brushes
AU654833B2 (en) The use of pairs of peptides with extremely high specific affinity for one another in the area of in vitro diagnosis
JP2004512258A5 (enExample)
WO1999017120A1 (en) Preparing conjugates using polyethylene glycol linkers
JPH10509731A (ja) ホスファターゼ活性化架橋剤、結合剤及び還元剤とその使用方法、並びにホスファターゼ活性化架橋剤及び結合剤を含む試薬
US5518882A (en) Immunological methods of component selection and recovery
EP1176423B1 (en) Surface-attached polyfunctional polymer networks for sensor chips
CN1300581C (zh) Sars病毒抗体检测方法及快速诊断试剂盒和制备方法
JPH11124396A (ja) 樹状ポリペプチド
JP2824516B2 (ja) 免疫学的に検出可能な物質の測定法、反応容器及びイムノアッセイ原理による方法における種々のパラメーターの測定法
WO2003104424A2 (en) Novel molecular conjugates for signal amplification
JPH0587520B2 (enExample)
US20050282884A1 (en) N-aryl-carbamic acid ester-derived and valeric acid ester-derived cross-linkers and conjugates, and methods for their synthesis and use
JP2509840B2 (ja) 免疫測定法及び免疫測定用試薬キット
JPH08133990A (ja) 反応性マイクロスフェアー
KR100668337B1 (ko) 단백질에 비하여 핵산에 대한 결합력이 선택적으로 높은pH 의존성 이온 교환물질, 그가 고정화되어 있는 고체기판, 및 상기 물질 및 고체 기판을 이용하여 핵산을분리하는 방법
JP2547149B2 (ja) 免疫測定法及び免疫測定用試薬キット
JP2003532420A5 (enExample)
CN110501495A (zh) 活化氨基固相颗粒与免疫氨基固相颗粒及其制备方法和应用及试剂盒
CA2195752A1 (en) Oligomeric carrier molecules with defined incorporated marker groups andhaptens
KR100668338B1 (ko) 신규한 pH 의존성 이온 교환물질, 그가 고정화되어 있는고체 기판, 및 상기 물질 및 고체 기판을 이용하여 핵산을분리하는 방법