JP2010506952A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2010506952A5 JP2010506952A5 JP2009533509A JP2009533509A JP2010506952A5 JP 2010506952 A5 JP2010506952 A5 JP 2010506952A5 JP 2009533509 A JP2009533509 A JP 2009533509A JP 2009533509 A JP2009533509 A JP 2009533509A JP 2010506952 A5 JP2010506952 A5 JP 2010506952A5
- Authority
- JP
- Japan
- Prior art keywords
- gel formulation
- present
- diclofenac
- gel
- dmso
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 claims 19
- 238000009472 formulation Methods 0.000 claims 17
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 claims 15
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims 15
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 10
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims 9
- DCOPUUMXTXDBNB-UHFFFAOYSA-N diclofenac Chemical compound OC(=O)CC1=CC=CC=C1NC1=C(Cl)C=CC=C1Cl DCOPUUMXTXDBNB-UHFFFAOYSA-N 0.000 claims 6
- 239000000041 non-steroidal anti-inflammatory agent Substances 0.000 claims 6
- 229940021182 non-steroidal anti-inflammatory drug Drugs 0.000 claims 6
- 229960001259 diclofenac Drugs 0.000 claims 5
- 229960001193 diclofenac sodium Drugs 0.000 claims 5
- 239000003814 drug Substances 0.000 claims 5
- 150000003839 salts Chemical class 0.000 claims 5
- JGMJQSFLQWGYMQ-UHFFFAOYSA-M sodium;2,6-dichloro-n-phenylaniline;acetate Chemical compound [Na+].CC([O-])=O.ClC1=CC=CC(Cl)=C1NC1=CC=CC=C1 JGMJQSFLQWGYMQ-UHFFFAOYSA-M 0.000 claims 5
- 239000002562 thickening agent Substances 0.000 claims 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 5
- NIXOWILDQLNWCW-UHFFFAOYSA-N Acrylic acid Chemical compound OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims 4
- 239000001913 cellulose Substances 0.000 claims 4
- 229920002678 cellulose Polymers 0.000 claims 4
- 229920000642 polymer Polymers 0.000 claims 4
- 208000006820 Arthralgia Diseases 0.000 claims 3
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 claims 2
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims 2
- 208000002193 Pain Diseases 0.000 claims 2
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 claims 2
- 229920002125 Sokalan® Polymers 0.000 claims 2
- 229960001631 carbomer Drugs 0.000 claims 2
- 125000001664 diethylamino group Chemical class [H]C([H])([H])C([H])([H])N(*)C([H])([H])C([H])([H])[H] 0.000 claims 2
- 239000001863 hydroxypropyl cellulose Substances 0.000 claims 2
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 201000008482 osteoarthritis Diseases 0.000 claims 2
- 229910052700 potassium Inorganic materials 0.000 claims 2
- 239000011591 potassium Substances 0.000 claims 2
- 238000002360 preparation method Methods 0.000 claims 2
- 229910052708 sodium Inorganic materials 0.000 claims 2
- 239000011734 sodium Substances 0.000 claims 2
- 239000004372 Polyvinyl alcohol Substances 0.000 claims 1
- 230000000052 comparative effect Effects 0.000 claims 1
- 238000001035 drying Methods 0.000 claims 1
- 230000004907 flux Effects 0.000 claims 1
- 150000004676 glycans Chemical class 0.000 claims 1
- 239000012669 liquid formulation Substances 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 229920001983 poloxamer Polymers 0.000 claims 1
- 229920001282 polysaccharide Polymers 0.000 claims 1
- 239000005017 polysaccharide Substances 0.000 claims 1
- 229920002451 polyvinyl alcohol Polymers 0.000 claims 1
- 238000011200 topical administration Methods 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US82975606P | 2006-10-17 | 2006-10-17 | |
| US60/829,756 | 2006-10-17 | ||
| PCT/US2007/081674 WO2008049020A2 (en) | 2006-10-17 | 2007-10-17 | Diclofenac gel |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010506952A JP2010506952A (ja) | 2010-03-04 |
| JP2010506952A5 true JP2010506952A5 (enExample) | 2010-12-02 |
| JP5432716B2 JP5432716B2 (ja) | 2014-03-05 |
Family
ID=39023542
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009533509A Expired - Fee Related JP5432716B2 (ja) | 2006-10-17 | 2007-10-17 | ジクロフェナクゲル |
Country Status (14)
| Country | Link |
|---|---|
| US (14) | US8252838B2 (enExample) |
| EP (2) | EP2626063B1 (enExample) |
| JP (1) | JP5432716B2 (enExample) |
| CN (2) | CN101588791A (enExample) |
| AU (1) | AU2007311019B2 (enExample) |
| BR (1) | BRPI0717769A2 (enExample) |
| CA (1) | CA2666398C (enExample) |
| DK (1) | DK2086504T3 (enExample) |
| IL (1) | IL198161A (enExample) |
| MX (1) | MX2009004038A (enExample) |
| NZ (1) | NZ577020A (enExample) |
| RU (1) | RU2463038C2 (enExample) |
| WO (1) | WO2008049020A2 (enExample) |
| ZA (1) | ZA200903135B (enExample) |
Families Citing this family (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1966229B1 (en) | 2005-09-12 | 2015-10-21 | Abela Pharmaceuticals, Inc. | Systems for removing dimethyl sulfoxide (dmso) or related compounds, or odors associated with same |
| US8480797B2 (en) | 2005-09-12 | 2013-07-09 | Abela Pharmaceuticals, Inc. | Activated carbon systems for facilitating use of dimethyl sulfoxide (DMSO) by removal of same, related compounds, or associated odors |
| US8435224B2 (en) * | 2005-09-12 | 2013-05-07 | Abela Pharmaceuticals, Inc. | Materials for facilitating administration of dimethyl sulfoxide (DMSO) and related compounds |
| EP1937286B1 (en) | 2005-09-12 | 2016-03-09 | Abela Pharmaceuticals, Inc. | Compositions comprising dimethyl sulfoxide (dmso) |
| ZA200903135B (en) | 2006-10-17 | 2010-08-25 | Nuvo Res Inc | Diclofenac gel |
| US20100100060A1 (en) * | 2008-10-17 | 2010-04-22 | Novartis Ag | Applicator for pharmaceutical product and method of using same |
| BRPI0921494A2 (pt) | 2008-11-03 | 2018-10-30 | Prad Reasearch And Development Ltd | método de planejamento de uma operação de amostragem para uma formação subterrãnea, método de contolar uma operação de amostragem de formação subterrânea, método de controlar uma operação de perfuração para uma formação subterrãnea, e método de realizar uma amostragem durante a operação de perfuração. |
| US8546450B1 (en) | 2009-03-31 | 2013-10-01 | Nuvo Research Inc. | Treatment of pain with topical diclofenac compounds |
| US8618164B2 (en) | 2009-03-31 | 2013-12-31 | Nuvo Research Inc. | Treatment of pain with topical diclofenac compounds |
| EP2482850A2 (en) * | 2009-09-30 | 2012-08-08 | Nuvo Research Inc. | Topical formulations |
| WO2011044540A1 (en) | 2009-10-09 | 2011-04-14 | Nuvo Research Inc. | Topical formulation comprising etoricoxib and a zwitterionic surfactant |
| JP5947721B2 (ja) | 2009-10-30 | 2016-07-06 | アベラ ファーマスーティカルズ インコーポレイテッド | 変形性関節症を治療するためのジメチルスルホキシド（ｄｍｓｏ）およびメチルスルホニルメタン（ｍｓｍ）製剤 |
| WO2011060195A2 (en) | 2009-11-11 | 2011-05-19 | Nuvo Research Inc. | Topical eutectic formulation |
| EP2329849B1 (en) | 2009-11-18 | 2015-04-29 | Galderma Research & Development | Combination of alpha-2 adrenergic receptor agonist and non-steroidal anti-inflammatory agent for treating or preventing an inflammatory skin disorder |
| CA2828086C (en) | 2010-03-10 | 2018-07-31 | Nuvo Research Inc. | Foamable formulation |
| WO2011149645A1 (en) | 2010-05-28 | 2011-12-01 | Nuvo Research Inc. | Topical etoricoxib formulation |
| KR20140027319A (ko) * | 2011-05-26 | 2014-03-06 | 노파르티스 아게 | 생리학상 활성제의 경피 투여를 위한 조성물 |
| US10813897B2 (en) * | 2011-12-27 | 2020-10-27 | Cmpd Licensing, Llc | Composition and method for compounded therapy |
| CN102525886B (zh) * | 2012-01-13 | 2013-03-13 | 湖北科益药业股份有限公司 | 双氯芬酸二乙胺乳胶剂及其制备方法 |
| FR2990134B1 (fr) * | 2012-05-07 | 2014-11-21 | Anaconda Pharma | Composition pharmaceutique d'un inhibiteur du virus du papillome |
| US8853189B2 (en) * | 2012-05-31 | 2014-10-07 | Prima Innovations, Llc | Antispasmodic 1,2-Diols and 1,2,3-triols |
| ITMI20121205A1 (it) | 2012-07-11 | 2014-01-12 | Glycores 2000 Srl | Composizione con attivita' antinfiammatoria ed analgesica da somministrare per uso esterno mediante vaporizzazione |
| US20140113970A1 (en) * | 2012-10-22 | 2014-04-24 | Mallinckrodt LLC Covidien | Dispensing system |
| EP2742932A1 (en) * | 2012-12-17 | 2014-06-18 | Laboratorios Ojer Pharma S.L. | Gel compositions |
| ES2613721T3 (es) | 2012-12-21 | 2017-05-25 | Teikoku Pharma Usa, Inc. | Composiciones y métodos para administración transdérmica de hormonas y otros agentes medicinales |
| US9012402B1 (en) | 2014-06-11 | 2015-04-21 | James Blanchard | Gel for topical delivery of NSAIDs to provide relief of musculoskeletal pain and methods for its preparation |
| RU2711090C2 (ru) * | 2015-01-23 | 2020-01-15 | Др. Редди'С Лабораториз Лимитед | Неокрашивающая гелевая композиция, содержащая нимесулид, для местного применения |
| WO2017172603A1 (en) | 2016-03-28 | 2017-10-05 | Tioga Research, Inc. | Topical formulation |
| MY193175A (en) * | 2016-03-30 | 2022-09-26 | Sarudbhava Formulations Private Ltd | Apremilast pharmaceutical compositions |
| US11666531B2 (en) * | 2016-03-31 | 2023-06-06 | Smartech Topical, Inc. | Delivery system |
| IT201700009711A1 (it) * | 2017-01-30 | 2018-07-30 | Applied Pharma Res | Sodium free Diclofenac potassium oral solutions Soluzioni orali di Diclofenac potassico prive di sodio |
| US20200009157A1 (en) * | 2017-02-28 | 2020-01-09 | John W. Backer | Dimethyl sulfoxide (dmso) and hydrocortisone compositions and methods of use |
| US10821075B1 (en) | 2017-07-12 | 2020-11-03 | James Blanchard | Compositions for topical application of a medicaments onto a mammalian body surface |
| WO2020106306A1 (en) | 2018-11-20 | 2020-05-28 | Nflection Therapeutics, Inc. | Cyanoaryl-aniline compounds for treatment of dermal disorders |
| US12378240B2 (en) | 2018-11-20 | 2025-08-05 | Nflection Therapeutics, Inc. | Naphthyridinone-aniline compounds for treatment of dermal disorders |
| WO2020106304A1 (en) * | 2018-11-20 | 2020-05-28 | Nflection Therapeutics, Inc. | Topical formulations |
| JP7546297B2 (ja) | 2018-11-20 | 2024-09-06 | エヌフレクション セラピューティクス インコーポレイテッド | 皮膚障害の処置のためのチエニル－アニリン化合物 |
| WO2021061913A1 (en) * | 2019-09-27 | 2021-04-01 | Encube Ethicals, Pvt. Ltd. | Diclofenac sodium topical solution |
| CN114615974B (zh) | 2019-11-06 | 2025-01-03 | 智能科技专题有限公司 | 环加氧酶抑制剂的局部制剂及其用途 |
| CN110687229A (zh) * | 2019-11-12 | 2020-01-14 | 山东省药学科学院 | 一种双氯芬酸钠原料及其制剂中有关物质的分析方法 |
| US12324854B2 (en) | 2020-08-26 | 2025-06-10 | Canadian Nano Pharmaceutical Technology Inc. | Nano-emulsion based compositions, methods for their preparation and their use in delivery of active ingredients |
| WO2022055927A1 (en) * | 2020-09-11 | 2022-03-17 | Ps Therapy Ltd. | Topical compositions and methods of use |
| JP2024540631A (ja) | 2021-11-23 | 2024-10-31 | エヌフレクション セラピューティクス インコーポレイテッド | ピロロピリジン－アニリン化合物の製剤 |
| CN114259461B (zh) * | 2021-11-29 | 2023-09-12 | 海南全星制药有限公司 | 一种双氯芬酸钠凝胶及其制备方法 |
| EP4499036A1 (en) | 2022-03-25 | 2025-02-05 | Glycores 2000 srl | Topical pharmaceutical composition with anti-inflammatory and analgesic activity and uses thereof |
| CN116869976A (zh) * | 2023-09-07 | 2023-10-13 | 晶易医药科技(成都)有限公司 | 双氯芬酸二乙胺凝胶贴膏组合物、凝胶贴膏及其制备方法 |
Family Cites Families (59)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4342784A (en) * | 1964-10-06 | 1982-08-03 | E. R. Squibb & Sons, Inc. | Chemical compositions and method of utilization |
| US3740421A (en) * | 1966-09-19 | 1973-06-19 | Basf Wyandotte Corp | Polyoxyethylene-polyoxypropylene aqueous gels |
| US3740420A (en) | 1967-11-28 | 1973-06-19 | Crown Zellerbach Corp | Pharmaceutical compositions with dimethyl sulfoxide |
| US3711602A (en) | 1970-10-30 | 1973-01-16 | Crown Zellerbach Corp | Compositions for topical application for enhancing tissue penetration of physiologically active agents with dmso |
| GB2023000B (en) | 1978-06-17 | 1982-10-13 | Kowa Co | Antinflammatory analgesic gelled ointments |
| US4296104A (en) | 1979-08-30 | 1981-10-20 | Herschler R J | Therapeutic dimethyl sulfoxide composition and methods of use |
| US4441739A (en) | 1981-08-27 | 1984-04-10 | Cluff Warren S | Booklet |
| US4543251A (en) * | 1983-12-09 | 1985-09-24 | Toko Yakuhin Industry Co., Ltd. | Gel preparations for external application |
| US4670254A (en) | 1983-12-09 | 1987-06-02 | Toko Yakuhin Industry Co., Ltd. | Gel preparations for topical application of diclofenac sodium |
| CA1236029A (en) * | 1984-05-14 | 1988-05-03 | Edmund Sandborn | Pharmaceutical solutions comprising dimethyl sulfoxide |
| JPS61254519A (ja) * | 1985-05-07 | 1986-11-12 | Nitto Electric Ind Co Ltd | ゲル状医薬製剤 |
| JPS61277613A (ja) * | 1985-05-31 | 1986-12-08 | Nitto Electric Ind Co Ltd | ゲル状外用医薬組成物 |
| US4707354A (en) | 1985-06-17 | 1987-11-17 | Alpen Tau, Inc. | Mature skin treatment and protectant compositions and methods of using same |
| JPH06104624B2 (ja) * | 1986-05-07 | 1994-12-21 | 太郎 小木曽 | 経皮吸収剤 |
| DE3632359A1 (de) * | 1986-09-24 | 1988-04-07 | Troponwerke Gmbh & Co Kg | Arzneimittelzubereitungen |
| US4855294A (en) * | 1988-09-06 | 1989-08-08 | Theratech, Inc. | Method for reducing skin irritation associated with drug/penetration enhancer compositions |
| US5215739A (en) | 1989-04-05 | 1993-06-01 | Toko Yakuhin Kogyo Kabushiki Kaisha | Spray gel base and spray gel preparation using thereof |
| ATE124627T1 (de) * | 1990-04-05 | 1995-07-15 | Sagitta Arzneimittel Gmbh | Diclofenac-natrium enthaltende pharmazeutische zusammensetzung zur topischen anwendung. |
| WO1992007561A1 (en) * | 1990-10-30 | 1992-05-14 | Ss Pharmaceutical Co., Ltd. | Antiphlogistic and analgesic gel preparation |
| US5874479A (en) | 1991-03-01 | 1999-02-23 | Warner-Lambert Company | Therapeutic permeation enhanced-wound healing compositions and methods for preparing and using same |
| US5674912A (en) | 1991-03-01 | 1997-10-07 | Warner-Lambert Company | Sunscreen-wound healing compositions and methods for preparing and using same |
| CA2112751A1 (en) | 1991-07-03 | 1993-01-21 | Charles J. Ii Betlach | Composition and method for transdermal delivery of diclofenac |
| IL101387A (en) | 1992-03-26 | 1999-11-30 | Pharmos Ltd | Emulsion with enhanced topical and/or transdermal systemic effect utilizing submicron oil droplets |
| JP2523428B2 (ja) | 1992-12-04 | 1996-08-07 | エスエス製薬株式会社 | 消炎鎮痛ゲル製剤 |
| DE4313402A1 (de) | 1993-04-23 | 1994-10-27 | Hexal Pharma Gmbh | Transdermale Wirkstoffzubereitung |
| WO1997013528A1 (en) * | 1995-10-12 | 1997-04-17 | Gs Development Ab | A pharmaceutical composition for administration of an active substance to or through a skin or mucosal surface |
| AUPO379596A0 (en) | 1996-11-22 | 1996-12-19 | Soltec Research Pty Ltd | Percutaneous delivery system |
| JP3291222B2 (ja) | 1997-05-19 | 2002-06-10 | トヨタ自動車株式会社 | 軟質光輝化製品 |
| US5976566A (en) * | 1997-08-29 | 1999-11-02 | Macrochem Corporation | Non-steroidal antiinflammtory drug formulations for topical application to the skin |
| US6399093B1 (en) | 1999-05-19 | 2002-06-04 | Advanced Medical Instruments | Method and composition to treat musculoskeletal disorders |
| US6962691B1 (en) | 1999-05-20 | 2005-11-08 | U & I Pharmaceuticals Ltd. | Topical spray compositions |
| KR100433614B1 (ko) | 2000-06-16 | 2004-05-31 | 주식회사 태평양 | 친수성 또는 염의 형태로 된 약물을 함유하는 경피흡수제제 |
| US6387383B1 (en) | 2000-08-03 | 2002-05-14 | Dow Pharmaceutical Sciences | Topical low-viscosity gel composition |
| EA200301200A1 (ru) | 2001-05-31 | 2004-06-24 | Фармация Корпорейшн | Проникающая через кожу композиция селективного ингибитора циклооксигеназы-2 |
| US6858200B2 (en) | 2001-06-06 | 2005-02-22 | Schering-Plough Healthcare Healthcare Products Inc. | Sunscreen formulations |
| US6750291B2 (en) | 2002-04-12 | 2004-06-15 | Pacific Corporation | Film-forming agent for drug delivery and preparation for percutaneous administration containing the same |
| ITMI20020986A1 (it) | 2002-05-10 | 2003-11-10 | Acraf | Composizione a base di diclofenac per il trattamento topico di affezioni del cavo orofaringeo |
| AR041021A1 (es) * | 2002-08-22 | 2005-04-27 | Novartis Consumer Health Sa | Composicion topica |
| US7138394B2 (en) | 2002-09-27 | 2006-11-21 | Alpharx Inc. | Vehicle for topical delivery of anti-inflammatory compounds |
| US20040175415A1 (en) | 2003-03-05 | 2004-09-09 | Chan Alvin C. | Formulations and methods of delivery of intact tocopheryl succinate to humans |
| US20040222123A1 (en) | 2003-05-06 | 2004-11-11 | Barr Laboratories, Inc. | Kit for pharmaceuticals |
| CA2530407A1 (en) * | 2003-07-23 | 2005-02-03 | The Regents Of The University Of California | Penetration enhancer combinations for transdermal delivery |
| DE20319986U1 (de) | 2003-12-23 | 2004-04-15 | Merckle Gmbh Chemisch Pharmazeutische Fabrik | Topische Zubereitungen enthaltend Dimethylsulfoxid und Dexpanthenol |
| US8252314B2 (en) | 2004-09-24 | 2012-08-28 | Hill's Pet Nutrition, Inc. | Hypoallergenic composition |
| CA2596194A1 (en) | 2004-11-24 | 2006-06-01 | Algorx Pharmaceuticals, Inc. | Capsaicinoid gel formulation and uses thereof |
| GT200600046A (es) | 2005-02-09 | 2006-09-25 | Terapia de combinacion | |
| US20070053984A1 (en) | 2005-03-03 | 2007-03-08 | Monique Spann-Wade | Topical gels compositions |
| KR20080008321A (ko) * | 2005-03-03 | 2008-01-23 | 아이에스더블유 그룹, 인크. | 국소 젤 조성물 |
| KR20080032209A (ko) | 2005-07-20 | 2008-04-14 | 파나세아 바이오테크 리미티드 | 사이클로옥시지네이즈 효소 억제제를 구성하는 새로운형태의 약학적 변형된 용출 용량형 조성물 |
| WO2007016766A1 (en) | 2005-08-05 | 2007-02-15 | Nuvo Research Inc. | Transdermal drug delivery formulation |
| US20070141182A1 (en) | 2005-12-20 | 2007-06-21 | Niazi Sarfaraz K | Combination of multiple nonteroidal antiinflammatory drugs and muscle relaxants for local treatment of musculoskeletal pain |
| EP1999626A4 (en) | 2006-01-26 | 2009-11-25 | Combinatorx Inc | METHODS, COMPOSITIONS AND NEEDS FOR TREATING MUSCULOSKELETAL DISORDERS AND SYMPTOMS ASSOCIATED THEREWITH |
| US20070280972A1 (en) * | 2006-04-25 | 2007-12-06 | Zars, Inc. | Adhesive solid gel-forming formulations for dermal drug delivery |
| ZA200903135B (en) | 2006-10-17 | 2010-08-25 | Nuvo Res Inc | Diclofenac gel |
| EP2077724A2 (en) | 2007-01-16 | 2009-07-15 | Tyratech, Inc. | Pest control compositions and methods |
| EA201100863A1 (ru) | 2008-11-28 | 2011-12-30 | Эдванс Холдингз Лимитед | Фармацевтическая композиция, включающая диклофенак и сложный эфир гидроксижирной кислоты и полиоксиалкилена |
| US8546450B1 (en) | 2009-03-31 | 2013-10-01 | Nuvo Research Inc. | Treatment of pain with topical diclofenac compounds |
| US8618164B2 (en) | 2009-03-31 | 2013-12-31 | Nuvo Research Inc. | Treatment of pain with topical diclofenac compounds |
| US20140113970A1 (en) | 2012-10-22 | 2014-04-24 | Mallinckrodt LLC Covidien | Dispensing system |
-
2007
- 2007-10-17 ZA ZA200903135A patent/ZA200903135B/xx unknown
- 2007-10-17 NZ NZ577020A patent/NZ577020A/en not_active IP Right Cessation
- 2007-10-17 DK DK07863421T patent/DK2086504T3/da active
- 2007-10-17 RU RU2009118392/15A patent/RU2463038C2/ru not_active IP Right Cessation
- 2007-10-17 WO PCT/US2007/081674 patent/WO2008049020A2/en not_active Ceased
- 2007-10-17 EP EP13166999.6A patent/EP2626063B1/en active Active
- 2007-10-17 BR BRPI0717769 patent/BRPI0717769A2/pt not_active Application Discontinuation
- 2007-10-17 JP JP2009533509A patent/JP5432716B2/ja not_active Expired - Fee Related
- 2007-10-17 CA CA2666398A patent/CA2666398C/en active Active
- 2007-10-17 AU AU2007311019A patent/AU2007311019B2/en not_active Ceased
- 2007-10-17 CN CNA2007800464038A patent/CN101588791A/zh active Pending
- 2007-10-17 CN CN201410667941.0A patent/CN104606126A/zh active Pending
- 2007-10-17 EP EP20070863421 patent/EP2086504B1/en active Active
- 2007-10-17 MX MX2009004038A patent/MX2009004038A/es active IP Right Grant
-
2008
- 2008-06-05 US US12/134,121 patent/US8252838B2/en not_active Expired - Fee Related
-
2009
- 2009-04-16 IL IL198161A patent/IL198161A/en active IP Right Grant
-
2012
- 2012-08-01 US US13/564,688 patent/US8563613B2/en not_active Expired - Fee Related
-
2013
- 2013-09-12 US US14/025,781 patent/US8871809B2/en active Active
-
2014
- 2014-09-25 US US14/497,096 patent/US9066913B2/en not_active Expired - Fee Related
-
2015
- 2015-01-14 US US14/596,919 patent/US9101591B2/en not_active Expired - Fee Related
- 2015-01-14 US US14/596,813 patent/US20150126606A1/en not_active Abandoned
- 2015-05-06 US US14/705,649 patent/US9220784B2/en active Active
- 2015-05-06 US US14/705,606 patent/US9168304B2/en active Active
- 2015-05-06 US US14/705,636 patent/US9168305B2/en active Active
- 2015-05-06 US US14/705,593 patent/US9339551B2/en not_active Expired - Fee Related
- 2015-10-26 US US14/922,903 patent/US9339552B2/en not_active Expired - Fee Related
-
2016
- 2016-04-06 US US15/092,139 patent/US9539335B2/en not_active Expired - Fee Related
- 2016-12-05 US US15/368,781 patent/US20170266296A1/en not_active Abandoned
-
2019
- 2019-09-18 US US16/575,120 patent/US20200237919A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2010506952A5 (enExample) | ||
| RU2009118392A (ru) | Диклофенаковый гель | |
| TWI510235B (zh) | 消炎鎮痛外用劑 | |
| JP5542665B2 (ja) | マトリックス型経皮投与剤およびその製造方法 | |
| JP2013515002A5 (enExample) | ||
| JP2010521442A (ja) | 局所製剤処方 | |
| JP2004269528A (ja) | ヘルペスウイルス感染により引き起こされる疼痛又は炎症の緩和に有効な局所皮膚適用製剤 | |
| JPH0315606B2 (enExample) | ||
| JP2001513543A (ja) | 皮膚への局所適用のための非ステロイド性抗炎症薬製剤 | |
| JP5421063B2 (ja) | ジクロフェナクナトリウム含有水性貼付剤 | |
| CN103108623A (zh) | 用于治疗浅表病变的组合物 | |
| JP2012508256A5 (enExample) | ||
| JP2005002040A (ja) | 消炎鎮痛貼付剤 | |
| JP2011513276A (ja) | 滅菌されたスクラルフェートゲル | |
| JPH04193826A (ja) | ジクロフェナクナトリウム含有の経皮吸収型消炎・鎮痛貼布剤 | |
| JP2012526099A5 (enExample) | ||
| JP2004026721A (ja) | 温感外用剤組成物 | |
| US8236814B2 (en) | Composition and method for treatment of warts | |
| CN105326818B (zh) | 一种双氯酚酸钠贴剂 | |
| JPH0124129B2 (enExample) | ||
| CA2570599C (en) | Pharmaceutical compositions for drug delivery and methods of treating or preventing conditions using same | |
| JP2010280609A (ja) | 肩こり、腰痛、筋肉痛、打撲、捻挫、頸肩腕症候群及び外傷による内出血の治療剤 | |
| JPS6127920A (ja) | 消炎鎮痛性外用医薬組成物 | |
| JP2017533921A (ja) | 噴霧可能な鎮痛剤組成物 | |
| JP3612731B2 (ja) | 消炎鎮痛外用剤 |