FR2990134B1 - Composition pharmaceutique d'un inhibiteur du virus du papillome - Google Patents

Composition pharmaceutique d'un inhibiteur du virus du papillome

Info

Publication number
FR2990134B1
FR2990134B1 FR1254186A FR1254186A FR2990134B1 FR 2990134 B1 FR2990134 B1 FR 2990134B1 FR 1254186 A FR1254186 A FR 1254186A FR 1254186 A FR1254186 A FR 1254186A FR 2990134 B1 FR2990134 B1 FR 2990134B1
Authority
FR
France
Prior art keywords
pharmaceutical composition
papilloma virus
virus inhibitor
inhibitor
papilloma
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR1254186A
Other languages
English (en)
Other versions
FR2990134A1 (fr
Inventor
Marta Blumenfeld
Delphine Compere
Patricia Francon
Michel Hutin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Anaconda Pharma SAS
Original Assignee
Anaconda Pharma SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR1254186A priority Critical patent/FR2990134B1/fr
Application filed by Anaconda Pharma SAS filed Critical Anaconda Pharma SAS
Priority to CN201380023685.5A priority patent/CN104427971B/zh
Priority to ARP130101558A priority patent/AR090965A1/es
Priority to PCT/EP2013/059475 priority patent/WO2013167583A1/fr
Priority to RU2014148528A priority patent/RU2661007C2/ru
Priority to US14/399,354 priority patent/US9670159B2/en
Priority to JP2015510793A priority patent/JP2015522529A/ja
Priority to EP13721713.9A priority patent/EP2854758A1/fr
Priority to CA2872832A priority patent/CA2872832A1/fr
Publication of FR2990134A1 publication Critical patent/FR2990134A1/fr
Application granted granted Critical
Publication of FR2990134B1 publication Critical patent/FR2990134B1/fr
Priority to HK15106988.4A priority patent/HK1206273A1/xx
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/34—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4453—Non condensed piperidines, e.g. piperocaine only substituted in position 1, e.g. propipocaine, diperodon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/04—Drugs for disorders of the respiratory system for throat disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/12—Keratolytics, e.g. wart or anti-corn preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Pulmonology (AREA)
  • Reproductive Health (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Inorganic Chemistry (AREA)
  • Otolaryngology (AREA)
  • Endocrinology (AREA)
  • Dispersion Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
FR1254186A 2012-05-07 2012-05-07 Composition pharmaceutique d'un inhibiteur du virus du papillome Expired - Fee Related FR2990134B1 (fr)

Priority Applications (10)

Application Number Priority Date Filing Date Title
FR1254186A FR2990134B1 (fr) 2012-05-07 2012-05-07 Composition pharmaceutique d'un inhibiteur du virus du papillome
CA2872832A CA2872832A1 (fr) 2012-05-07 2013-05-07 Composition pharmaceutique d'un inhibiteur du virus du papillome
PCT/EP2013/059475 WO2013167583A1 (fr) 2012-05-07 2013-05-07 Composition pharmaceutique d'un inhibiteur du virus du papillome
RU2014148528A RU2661007C2 (ru) 2012-05-07 2013-05-07 Фармацевтическая композиция ингибитора папилломавируса
US14/399,354 US9670159B2 (en) 2012-05-07 2013-05-07 Pharmaceutical composition of a papillomavirus inhibitor
JP2015510793A JP2015522529A (ja) 2012-05-07 2013-05-07 パピローマウイルス阻害剤の医薬組成物
CN201380023685.5A CN104427971B (zh) 2012-05-07 2013-05-07 乳头瘤病毒抑制剂的药物组合物
ARP130101558A AR090965A1 (es) 2012-05-07 2013-05-07 Composicion farmaceutica de un inhibidor del virus del papiloma
EP13721713.9A EP2854758A1 (fr) 2012-05-07 2013-05-07 Composition pharmaceutique d'un inhibiteur du virus du papillome
HK15106988.4A HK1206273A1 (en) 2012-05-07 2015-07-22 Pharmaceutical composition of a papillomavirus inhibitor

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR1254186A FR2990134B1 (fr) 2012-05-07 2012-05-07 Composition pharmaceutique d'un inhibiteur du virus du papillome

Publications (2)

Publication Number Publication Date
FR2990134A1 FR2990134A1 (fr) 2013-11-08
FR2990134B1 true FR2990134B1 (fr) 2014-11-21

Family

ID=48407528

Family Applications (1)

Application Number Title Priority Date Filing Date
FR1254186A Expired - Fee Related FR2990134B1 (fr) 2012-05-07 2012-05-07 Composition pharmaceutique d'un inhibiteur du virus du papillome

Country Status (10)

Country Link
US (1) US9670159B2 (fr)
EP (1) EP2854758A1 (fr)
JP (1) JP2015522529A (fr)
CN (1) CN104427971B (fr)
AR (1) AR090965A1 (fr)
CA (1) CA2872832A1 (fr)
FR (1) FR2990134B1 (fr)
HK (1) HK1206273A1 (fr)
RU (1) RU2661007C2 (fr)
WO (1) WO2013167583A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2595832C9 (ru) * 2015-08-26 2016-10-27 Андрей Дмитриевич Протасов Способ достижения длительной клинической ремиссии хронической впч-инфекции, проявляющейся остроконечными кондиломами аногенитальной области

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2730645A1 (de) 1977-07-07 1979-01-25 Henkel Kgaa Verwendung von telomerisaten aus mercaptanen mit acrylverbindungen als steinschutz- und/oder korrosionsschutzmittel
DE2860931D1 (en) 1977-07-15 1981-11-12 Ici Australia Ltd Vinyl halide polymerization process
US5093133A (en) * 1990-01-24 1992-03-03 Mcneil-Ppc, Inc. Method for percutaneous delivery of ibuprofen using hydroalcoholic gel
RU2196568C1 (ru) * 2001-08-08 2003-01-20 Киселев Всеволод Иванович Фармацевтическая композиция для профилактики и лечения дисплазий и рака шейки матки и папилломатоза гортани, а также способ профилактики и лечения этих заболеваний на ее основе
FI20041425A0 (fi) * 2004-11-05 2004-11-05 Orion Corp Transmukosaalinen veterinäärinen koostumus
JP2008530022A (ja) * 2005-02-04 2008-08-07 コーリー ファーマシューティカル グループ，インコーポレイテッド 免疫反応調節物質を含む水性ゲル処方物
FR2901273B1 (fr) * 2006-05-19 2010-12-24 Anaconda Pharma Inhibiteurs du virus du papillome humain et les compositions pharmaceutiques les contenant
JP5432716B2 (ja) * 2006-10-17 2014-03-05 ヌーボ リサーチ インコーポレイテッド ジクロフェナクゲル
FR2923825B1 (fr) * 2007-11-20 2013-05-03 Anaconda Pharma Nouveaux inhibiteurs du virus du papillome humain et les compositions pharmaceutiques les contenant.

Also Published As

Publication number Publication date
RU2014148528A (ru) 2016-06-27
CN104427971B (zh) 2018-04-20
CN104427971A (zh) 2015-03-18
WO2013167583A1 (fr) 2013-11-14
EP2854758A1 (fr) 2015-04-08
RU2661007C2 (ru) 2018-07-11
US20150152051A1 (en) 2015-06-04
FR2990134A1 (fr) 2013-11-08
CA2872832A1 (fr) 2013-11-14
AR090965A1 (es) 2014-12-17
HK1206273A1 (en) 2016-01-08
US9670159B2 (en) 2017-06-06
JP2015522529A (ja) 2015-08-06

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