RU2463038C2 - Диклофенаковый гель - Google Patents

Диклофенаковый гель Download PDF

Info

Publication number
RU2463038C2
RU2463038C2 RU2009118392/15A RU2009118392A RU2463038C2 RU 2463038 C2 RU2463038 C2 RU 2463038C2 RU 2009118392/15 A RU2009118392/15 A RU 2009118392/15A RU 2009118392 A RU2009118392 A RU 2009118392A RU 2463038 C2 RU2463038 C2 RU 2463038C2
Authority
RU
Russia
Prior art keywords
composition
gel
diclofenac
compositions
diclofenac sodium
Prior art date
Application number
RU2009118392/15A
Other languages
English (en)
Russian (ru)
Other versions
RU2009118392A (ru
Inventor
Эд КИСАК (US)
Эд КИСАК
Джагат СИНГХ (CA)
Джагат СИНГХ
Original Assignee
Нуво Рисерч Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39023542&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=RU2463038(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Нуво Рисерч Инк. filed Critical Нуво Рисерч Инк.
Publication of RU2009118392A publication Critical patent/RU2009118392A/ru
Application granted granted Critical
Publication of RU2463038C2 publication Critical patent/RU2463038C2/ru

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183Amino acids, e.g. glycine, EDTA or aspartame
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Rheumatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
RU2009118392/15A 2006-10-17 2007-10-17 Диклофенаковый гель RU2463038C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US82975606P 2006-10-17 2006-10-17
US60/829,756 2006-10-17

Publications (2)

Publication Number Publication Date
RU2009118392A RU2009118392A (ru) 2010-11-27
RU2463038C2 true RU2463038C2 (ru) 2012-10-10

Family

ID=39023542

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2009118392/15A RU2463038C2 (ru) 2006-10-17 2007-10-17 Диклофенаковый гель

Country Status (14)

Country Link
US (14) US8252838B2 (enExample)
EP (2) EP2626063B1 (enExample)
JP (1) JP5432716B2 (enExample)
CN (2) CN101588791A (enExample)
AU (1) AU2007311019B2 (enExample)
BR (1) BRPI0717769A2 (enExample)
CA (1) CA2666398C (enExample)
DK (1) DK2086504T3 (enExample)
IL (1) IL198161A (enExample)
MX (1) MX2009004038A (enExample)
NZ (1) NZ577020A (enExample)
RU (1) RU2463038C2 (enExample)
WO (1) WO2008049020A2 (enExample)
ZA (1) ZA200903135B (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2637420C2 (ru) * 2012-10-22 2017-12-04 Нуво Фармасьютикалз Инк. Система дозированного распределения
RU2677892C2 (ru) * 2012-12-17 2019-01-22 Лабораториос Охер Фарма, С.Л. Гелевые композиции
RU2711090C2 (ru) * 2015-01-23 2020-01-15 Др. Редди'С Лабораториз Лимитед Неокрашивающая гелевая композиция, содержащая нимесулид, для местного применения

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1966229B1 (en) 2005-09-12 2015-10-21 Abela Pharmaceuticals, Inc. Systems for removing dimethyl sulfoxide (dmso) or related compounds, or odors associated with same
US8480797B2 (en) 2005-09-12 2013-07-09 Abela Pharmaceuticals, Inc. Activated carbon systems for facilitating use of dimethyl sulfoxide (DMSO) by removal of same, related compounds, or associated odors
US8435224B2 (en) * 2005-09-12 2013-05-07 Abela Pharmaceuticals, Inc. Materials for facilitating administration of dimethyl sulfoxide (DMSO) and related compounds
EP1937286B1 (en) 2005-09-12 2016-03-09 Abela Pharmaceuticals, Inc. Compositions comprising dimethyl sulfoxide (dmso)
ZA200903135B (en) 2006-10-17 2010-08-25 Nuvo Res Inc Diclofenac gel
US20100100060A1 (en) * 2008-10-17 2010-04-22 Novartis Ag Applicator for pharmaceutical product and method of using same
BRPI0921494A2 (pt) 2008-11-03 2018-10-30 Prad Reasearch And Development Ltd método de planejamento de uma operação de amostragem para uma formação subterrãnea, método de contolar uma operação de amostragem de formação subterrânea, método de controlar uma operação de perfuração para uma formação subterrãnea, e método de realizar uma amostragem durante a operação de perfuração.
US8546450B1 (en) 2009-03-31 2013-10-01 Nuvo Research Inc. Treatment of pain with topical diclofenac compounds
US8618164B2 (en) 2009-03-31 2013-12-31 Nuvo Research Inc. Treatment of pain with topical diclofenac compounds
EP2482850A2 (en) * 2009-09-30 2012-08-08 Nuvo Research Inc. Topical formulations
WO2011044540A1 (en) 2009-10-09 2011-04-14 Nuvo Research Inc. Topical formulation comprising etoricoxib and a zwitterionic surfactant
JP5947721B2 (ja) 2009-10-30 2016-07-06 アベラ ファーマスーティカルズ インコーポレイテッド 変形性関節症を治療するためのジメチルスルホキシド(dmso)およびメチルスルホニルメタン(msm)製剤
WO2011060195A2 (en) 2009-11-11 2011-05-19 Nuvo Research Inc. Topical eutectic formulation
EP2329849B1 (en) 2009-11-18 2015-04-29 Galderma Research & Development Combination of alpha-2 adrenergic receptor agonist and non-steroidal anti-inflammatory agent for treating or preventing an inflammatory skin disorder
CA2828086C (en) 2010-03-10 2018-07-31 Nuvo Research Inc. Foamable formulation
WO2011149645A1 (en) 2010-05-28 2011-12-01 Nuvo Research Inc. Topical etoricoxib formulation
KR20140027319A (ko) * 2011-05-26 2014-03-06 노파르티스 아게 생리학상 활성제의 경피 투여를 위한 조성물
US10813897B2 (en) * 2011-12-27 2020-10-27 Cmpd Licensing, Llc Composition and method for compounded therapy
CN102525886B (zh) * 2012-01-13 2013-03-13 湖北科益药业股份有限公司 双氯芬酸二乙胺乳胶剂及其制备方法
FR2990134B1 (fr) * 2012-05-07 2014-11-21 Anaconda Pharma Composition pharmaceutique d'un inhibiteur du virus du papillome
US8853189B2 (en) * 2012-05-31 2014-10-07 Prima Innovations, Llc Antispasmodic 1,2-Diols and 1,2,3-triols
ITMI20121205A1 (it) 2012-07-11 2014-01-12 Glycores 2000 Srl Composizione con attivita' antinfiammatoria ed analgesica da somministrare per uso esterno mediante vaporizzazione
ES2613721T3 (es) 2012-12-21 2017-05-25 Teikoku Pharma Usa, Inc. Composiciones y métodos para administración transdérmica de hormonas y otros agentes medicinales
US9012402B1 (en) 2014-06-11 2015-04-21 James Blanchard Gel for topical delivery of NSAIDs to provide relief of musculoskeletal pain and methods for its preparation
WO2017172603A1 (en) 2016-03-28 2017-10-05 Tioga Research, Inc. Topical formulation
MY193175A (en) * 2016-03-30 2022-09-26 Sarudbhava Formulations Private Ltd Apremilast pharmaceutical compositions
US11666531B2 (en) * 2016-03-31 2023-06-06 Smartech Topical, Inc. Delivery system
IT201700009711A1 (it) * 2017-01-30 2018-07-30 Applied Pharma Res Sodium free Diclofenac potassium oral solutions Soluzioni orali di Diclofenac potassico prive di sodio
US20200009157A1 (en) * 2017-02-28 2020-01-09 John W. Backer Dimethyl sulfoxide (dmso) and hydrocortisone compositions and methods of use
US10821075B1 (en) 2017-07-12 2020-11-03 James Blanchard Compositions for topical application of a medicaments onto a mammalian body surface
WO2020106306A1 (en) 2018-11-20 2020-05-28 Nflection Therapeutics, Inc. Cyanoaryl-aniline compounds for treatment of dermal disorders
US12378240B2 (en) 2018-11-20 2025-08-05 Nflection Therapeutics, Inc. Naphthyridinone-aniline compounds for treatment of dermal disorders
WO2020106304A1 (en) * 2018-11-20 2020-05-28 Nflection Therapeutics, Inc. Topical formulations
JP7546297B2 (ja) 2018-11-20 2024-09-06 エヌフレクション セラピューティクス インコーポレイテッド 皮膚障害の処置のためのチエニル-アニリン化合物
WO2021061913A1 (en) * 2019-09-27 2021-04-01 Encube Ethicals, Pvt. Ltd. Diclofenac sodium topical solution
CN114615974B (zh) 2019-11-06 2025-01-03 智能科技专题有限公司 环加氧酶抑制剂的局部制剂及其用途
CN110687229A (zh) * 2019-11-12 2020-01-14 山东省药学科学院 一种双氯芬酸钠原料及其制剂中有关物质的分析方法
US12324854B2 (en) 2020-08-26 2025-06-10 Canadian Nano Pharmaceutical Technology Inc. Nano-emulsion based compositions, methods for their preparation and their use in delivery of active ingredients
WO2022055927A1 (en) * 2020-09-11 2022-03-17 Ps Therapy Ltd. Topical compositions and methods of use
JP2024540631A (ja) 2021-11-23 2024-10-31 エヌフレクション セラピューティクス インコーポレイテッド ピロロピリジン-アニリン化合物の製剤
CN114259461B (zh) * 2021-11-29 2023-09-12 海南全星制药有限公司 一种双氯芬酸钠凝胶及其制备方法
EP4499036A1 (en) 2022-03-25 2025-02-05 Glycores 2000 srl Topical pharmaceutical composition with anti-inflammatory and analgesic activity and uses thereof
CN116869976A (zh) * 2023-09-07 2023-10-13 晶易医药科技(成都)有限公司 双氯芬酸二乙胺凝胶贴膏组合物、凝胶贴膏及其制备方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4652557A (en) * 1984-05-14 1987-03-24 Clark Pharmaceutical Laboratories Ltd. Pharmaceutical solutions comprising dimethyl sulfoxide
US5374661A (en) * 1991-07-03 1994-12-20 Sano Corporation Composition and method for transdermal delivery of diclofenac

Family Cites Families (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4342784A (en) * 1964-10-06 1982-08-03 E. R. Squibb & Sons, Inc. Chemical compositions and method of utilization
US3740421A (en) * 1966-09-19 1973-06-19 Basf Wyandotte Corp Polyoxyethylene-polyoxypropylene aqueous gels
US3740420A (en) 1967-11-28 1973-06-19 Crown Zellerbach Corp Pharmaceutical compositions with dimethyl sulfoxide
US3711602A (en) 1970-10-30 1973-01-16 Crown Zellerbach Corp Compositions for topical application for enhancing tissue penetration of physiologically active agents with dmso
GB2023000B (en) 1978-06-17 1982-10-13 Kowa Co Antinflammatory analgesic gelled ointments
US4296104A (en) 1979-08-30 1981-10-20 Herschler R J Therapeutic dimethyl sulfoxide composition and methods of use
US4441739A (en) 1981-08-27 1984-04-10 Cluff Warren S Booklet
US4543251A (en) * 1983-12-09 1985-09-24 Toko Yakuhin Industry Co., Ltd. Gel preparations for external application
US4670254A (en) 1983-12-09 1987-06-02 Toko Yakuhin Industry Co., Ltd. Gel preparations for topical application of diclofenac sodium
JPS61254519A (ja) * 1985-05-07 1986-11-12 Nitto Electric Ind Co Ltd ゲル状医薬製剤
JPS61277613A (ja) * 1985-05-31 1986-12-08 Nitto Electric Ind Co Ltd ゲル状外用医薬組成物
US4707354A (en) 1985-06-17 1987-11-17 Alpen Tau, Inc. Mature skin treatment and protectant compositions and methods of using same
JPH06104624B2 (ja) * 1986-05-07 1994-12-21 太郎 小木曽 経皮吸収剤
DE3632359A1 (de) * 1986-09-24 1988-04-07 Troponwerke Gmbh & Co Kg Arzneimittelzubereitungen
US4855294A (en) * 1988-09-06 1989-08-08 Theratech, Inc. Method for reducing skin irritation associated with drug/penetration enhancer compositions
US5215739A (en) 1989-04-05 1993-06-01 Toko Yakuhin Kogyo Kabushiki Kaisha Spray gel base and spray gel preparation using thereof
ATE124627T1 (de) * 1990-04-05 1995-07-15 Sagitta Arzneimittel Gmbh Diclofenac-natrium enthaltende pharmazeutische zusammensetzung zur topischen anwendung.
WO1992007561A1 (en) * 1990-10-30 1992-05-14 Ss Pharmaceutical Co., Ltd. Antiphlogistic and analgesic gel preparation
US5874479A (en) 1991-03-01 1999-02-23 Warner-Lambert Company Therapeutic permeation enhanced-wound healing compositions and methods for preparing and using same
US5674912A (en) 1991-03-01 1997-10-07 Warner-Lambert Company Sunscreen-wound healing compositions and methods for preparing and using same
IL101387A (en) 1992-03-26 1999-11-30 Pharmos Ltd Emulsion with enhanced topical and/or transdermal systemic effect utilizing submicron oil droplets
JP2523428B2 (ja) 1992-12-04 1996-08-07 エスエス製薬株式会社 消炎鎮痛ゲル製剤
DE4313402A1 (de) 1993-04-23 1994-10-27 Hexal Pharma Gmbh Transdermale Wirkstoffzubereitung
WO1997013528A1 (en) * 1995-10-12 1997-04-17 Gs Development Ab A pharmaceutical composition for administration of an active substance to or through a skin or mucosal surface
AUPO379596A0 (en) 1996-11-22 1996-12-19 Soltec Research Pty Ltd Percutaneous delivery system
JP3291222B2 (ja) 1997-05-19 2002-06-10 トヨタ自動車株式会社 軟質光輝化製品
US5976566A (en) * 1997-08-29 1999-11-02 Macrochem Corporation Non-steroidal antiinflammtory drug formulations for topical application to the skin
US6399093B1 (en) 1999-05-19 2002-06-04 Advanced Medical Instruments Method and composition to treat musculoskeletal disorders
US6962691B1 (en) 1999-05-20 2005-11-08 U & I Pharmaceuticals Ltd. Topical spray compositions
KR100433614B1 (ko) 2000-06-16 2004-05-31 주식회사 태평양 친수성 또는 염의 형태로 된 약물을 함유하는 경피흡수제제
US6387383B1 (en) 2000-08-03 2002-05-14 Dow Pharmaceutical Sciences Topical low-viscosity gel composition
EA200301200A1 (ru) 2001-05-31 2004-06-24 Фармация Корпорейшн Проникающая через кожу композиция селективного ингибитора циклооксигеназы-2
US6858200B2 (en) 2001-06-06 2005-02-22 Schering-Plough Healthcare Healthcare Products Inc. Sunscreen formulations
US6750291B2 (en) 2002-04-12 2004-06-15 Pacific Corporation Film-forming agent for drug delivery and preparation for percutaneous administration containing the same
ITMI20020986A1 (it) 2002-05-10 2003-11-10 Acraf Composizione a base di diclofenac per il trattamento topico di affezioni del cavo orofaringeo
AR041021A1 (es) * 2002-08-22 2005-04-27 Novartis Consumer Health Sa Composicion topica
US7138394B2 (en) 2002-09-27 2006-11-21 Alpharx Inc. Vehicle for topical delivery of anti-inflammatory compounds
US20040175415A1 (en) 2003-03-05 2004-09-09 Chan Alvin C. Formulations and methods of delivery of intact tocopheryl succinate to humans
US20040222123A1 (en) 2003-05-06 2004-11-11 Barr Laboratories, Inc. Kit for pharmaceuticals
CA2530407A1 (en) * 2003-07-23 2005-02-03 The Regents Of The University Of California Penetration enhancer combinations for transdermal delivery
DE20319986U1 (de) 2003-12-23 2004-04-15 Merckle Gmbh Chemisch Pharmazeutische Fabrik Topische Zubereitungen enthaltend Dimethylsulfoxid und Dexpanthenol
US8252314B2 (en) 2004-09-24 2012-08-28 Hill's Pet Nutrition, Inc. Hypoallergenic composition
CA2596194A1 (en) 2004-11-24 2006-06-01 Algorx Pharmaceuticals, Inc. Capsaicinoid gel formulation and uses thereof
GT200600046A (es) 2005-02-09 2006-09-25 Terapia de combinacion
US20070053984A1 (en) 2005-03-03 2007-03-08 Monique Spann-Wade Topical gels compositions
KR20080008321A (ko) * 2005-03-03 2008-01-23 아이에스더블유 그룹, 인크. 국소 젤 조성물
KR20080032209A (ko) 2005-07-20 2008-04-14 파나세아 바이오테크 리미티드 사이클로옥시지네이즈 효소 억제제를 구성하는 새로운형태의 약학적 변형된 용출 용량형 조성물
WO2007016766A1 (en) 2005-08-05 2007-02-15 Nuvo Research Inc. Transdermal drug delivery formulation
US20070141182A1 (en) 2005-12-20 2007-06-21 Niazi Sarfaraz K Combination of multiple nonteroidal antiinflammatory drugs and muscle relaxants for local treatment of musculoskeletal pain
EP1999626A4 (en) 2006-01-26 2009-11-25 Combinatorx Inc METHODS, COMPOSITIONS AND NEEDS FOR TREATING MUSCULOSKELETAL DISORDERS AND SYMPTOMS ASSOCIATED THEREWITH
US20070280972A1 (en) * 2006-04-25 2007-12-06 Zars, Inc. Adhesive solid gel-forming formulations for dermal drug delivery
ZA200903135B (en) 2006-10-17 2010-08-25 Nuvo Res Inc Diclofenac gel
EP2077724A2 (en) 2007-01-16 2009-07-15 Tyratech, Inc. Pest control compositions and methods
EA201100863A1 (ru) 2008-11-28 2011-12-30 Эдванс Холдингз Лимитед Фармацевтическая композиция, включающая диклофенак и сложный эфир гидроксижирной кислоты и полиоксиалкилена
US8546450B1 (en) 2009-03-31 2013-10-01 Nuvo Research Inc. Treatment of pain with topical diclofenac compounds
US8618164B2 (en) 2009-03-31 2013-12-31 Nuvo Research Inc. Treatment of pain with topical diclofenac compounds
US20140113970A1 (en) 2012-10-22 2014-04-24 Mallinckrodt LLC Covidien Dispensing system

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4652557A (en) * 1984-05-14 1987-03-24 Clark Pharmaceutical Laboratories Ltd. Pharmaceutical solutions comprising dimethyl sulfoxide
US5374661A (en) * 1991-07-03 1994-12-20 Sano Corporation Composition and method for transdermal delivery of diclofenac

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
BABOOTA S. «Formulation and evaluation of once-a-day transdermal gels of diclofenac diethylamine» Methods Find Exp Clin Pharmacol, 28 (2), 2006, с.109-114. *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2637420C2 (ru) * 2012-10-22 2017-12-04 Нуво Фармасьютикалз Инк. Система дозированного распределения
RU2677892C2 (ru) * 2012-12-17 2019-01-22 Лабораториос Охер Фарма, С.Л. Гелевые композиции
RU2711090C2 (ru) * 2015-01-23 2020-01-15 Др. Редди'С Лабораториз Лимитед Неокрашивающая гелевая композиция, содержащая нимесулид, для местного применения

Also Published As

Publication number Publication date
US20150231263A1 (en) 2015-08-20
WO2008049020A3 (en) 2008-06-12
US9220784B2 (en) 2015-12-29
DK2086504T3 (da) 2014-04-07
ZA200903135B (en) 2010-08-25
US20120295978A1 (en) 2012-11-22
EP2086504A2 (en) 2009-08-12
US9168305B2 (en) 2015-10-27
CA2666398A1 (en) 2008-04-24
CN101588791A (zh) 2009-11-25
RU2009118392A (ru) 2010-11-27
NZ577020A (en) 2012-05-25
US9339551B2 (en) 2016-05-17
US20080300311A1 (en) 2008-12-04
CA2666398C (en) 2015-08-18
US20150011635A1 (en) 2015-01-08
US8563613B2 (en) 2013-10-22
CN104606126A (zh) 2015-05-13
BRPI0717769A2 (pt) 2013-11-05
US20140018427A1 (en) 2014-01-16
US20150231262A1 (en) 2015-08-20
US20170266296A1 (en) 2017-09-21
US8252838B2 (en) 2012-08-28
US9339552B2 (en) 2016-05-17
US9168304B2 (en) 2015-10-27
EP2626063B1 (en) 2022-03-16
JP2010506952A (ja) 2010-03-04
US9066913B2 (en) 2015-06-30
US9539335B2 (en) 2017-01-10
MX2009004038A (es) 2009-08-24
JP5432716B2 (ja) 2014-03-05
US8871809B2 (en) 2014-10-28
AU2007311019B2 (en) 2013-05-16
AU2007311019A1 (en) 2008-04-24
AU2007311019A8 (en) 2009-06-18
EP2086504B1 (en) 2014-01-08
EP2626063A1 (en) 2013-08-14
US20150126607A1 (en) 2015-05-07
US20160213784A1 (en) 2016-07-28
US20150231264A1 (en) 2015-08-20
US9101591B2 (en) 2015-08-11
US20200237919A1 (en) 2020-07-30
US20160045605A1 (en) 2016-02-18
WO2008049020A2 (en) 2008-04-24
IL198161A0 (en) 2009-12-24
IL198161A (en) 2015-09-24
US20150313998A1 (en) 2015-11-05
US20150126606A1 (en) 2015-05-07
HK1134024A1 (en) 2010-04-16

Similar Documents

Publication Publication Date Title
RU2463038C2 (ru) Диклофенаковый гель
EP2704703B1 (en) Transdermal compositions of ibuprofen and methods of use thereof
US20120232152A1 (en) Topical ibuprofen formulations
HK1134024B (en) Diclofenac gel
HK1188140A (en) Diclofenac gel
HK1190327A (en) Transdermal compositions of ibuprofen and methods of use thereof
HK1190327B (en) Transdermal compositions of ibuprofen and methods of use thereof

Legal Events

Date Code Title Description
PD4A Correction of name of patent owner
MM4A The patent is invalid due to non-payment of fees

Effective date: 20201018