JP2010504758A5 - - Google Patents
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- Publication number
- JP2010504758A5 JP2010504758A5 JP2009530433A JP2009530433A JP2010504758A5 JP 2010504758 A5 JP2010504758 A5 JP 2010504758A5 JP 2009530433 A JP2009530433 A JP 2009530433A JP 2009530433 A JP2009530433 A JP 2009530433A JP 2010504758 A5 JP2010504758 A5 JP 2010504758A5
- Authority
- JP
- Japan
- Prior art keywords
- xylose
- glucose
- recombinant
- ethanol
- strain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- SRBFZHDQGSBBOR-IOVATXLUSA-N D-xylopyranose Chemical compound O[C@@H]1COC(O)[C@H](O)[C@H]1O SRBFZHDQGSBBOR-IOVATXLUSA-N 0.000 claims description 36
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 27
- PYMYPHUHKUWMLA-UHFFFAOYSA-N arabinose Natural products OCC(O)C(O)C(O)C=O PYMYPHUHKUWMLA-UHFFFAOYSA-N 0.000 claims description 18
- SRBFZHDQGSBBOR-UHFFFAOYSA-N beta-D-Pyranose-Lyxose Natural products OC1COC(O)C(O)C1O SRBFZHDQGSBBOR-UHFFFAOYSA-N 0.000 claims description 18
- 241000588901 Zymomonas Species 0.000 claims description 12
- 230000000694 effects Effects 0.000 claims description 11
- 101001059186 Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4) Glucose-fructose oxidoreductase Proteins 0.000 claims description 9
- 108010009512 Glucose-fructose oxidoreductase Proteins 0.000 claims description 8
- 238000012239 gene modification Methods 0.000 claims description 8
- 230000005017 genetic modification Effects 0.000 claims description 8
- 235000013617 genetically modified food Nutrition 0.000 claims description 8
- 238000004519 manufacturing process Methods 0.000 claims description 2
- 230000004048 modification Effects 0.000 claims description 2
- 238000012986 modification Methods 0.000 claims description 2
- CSNNHWWHGAXBCP-UHFFFAOYSA-L Magnesium sulfate Chemical compound [Mg+2].[O-][S+2]([O-])([O-])[O-] CSNNHWWHGAXBCP-UHFFFAOYSA-L 0.000 description 8
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 7
- 239000008103 glucose Substances 0.000 description 7
- TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 description 6
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 description 6
- 239000000811 xylitol Substances 0.000 description 6
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 description 6
- 229960002675 xylitol Drugs 0.000 description 6
- 235000010447 xylitol Nutrition 0.000 description 6
- 238000002474 experimental method Methods 0.000 description 5
- 239000007836 KH2PO4 Substances 0.000 description 4
- 229940041514 candida albicans extract Drugs 0.000 description 4
- 238000003780 insertion Methods 0.000 description 4
- 230000037431 insertion Effects 0.000 description 4
- 229910052943 magnesium sulfate Inorganic materials 0.000 description 4
- 235000019341 magnesium sulphate Nutrition 0.000 description 4
- 229910000402 monopotassium phosphate Inorganic materials 0.000 description 4
- 235000019796 monopotassium phosphate Nutrition 0.000 description 4
- GNSKLFRGEWLPPA-UHFFFAOYSA-M potassium dihydrogen phosphate Chemical compound [K+].OP(O)([O-])=O GNSKLFRGEWLPPA-UHFFFAOYSA-M 0.000 description 4
- 239000012138 yeast extract Substances 0.000 description 4
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 description 3
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 3
- 230000007423 decrease Effects 0.000 description 3
- 238000000855 fermentation Methods 0.000 description 3
- 230000004151 fermentation Effects 0.000 description 3
- 239000002773 nucleotide Substances 0.000 description 3
- 125000003729 nucleotide group Chemical group 0.000 description 3
- 238000011218 seed culture Methods 0.000 description 3
- 108020005544 Antisense RNA Proteins 0.000 description 2
- 108020004705 Codon Proteins 0.000 description 2
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 description 2
- 108700026244 Open Reading Frames Proteins 0.000 description 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 description 2
- 238000004458 analytical method Methods 0.000 description 2
- 239000003184 complementary RNA Substances 0.000 description 2
- 238000012217 deletion Methods 0.000 description 2
- 230000037430 deletion Effects 0.000 description 2
- 239000001963 growth medium Substances 0.000 description 2
- 238000004128 high performance liquid chromatography Methods 0.000 description 2
- 239000002609 medium Substances 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 230000035772 mutation Effects 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 239000000600 sorbitol Substances 0.000 description 2
- 206010010144 Completed suicide Diseases 0.000 description 1
- 108020004414 DNA Proteins 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 238000012300 Sequence Analysis Methods 0.000 description 1
- 108091081024 Start codon Proteins 0.000 description 1
- 241000588902 Zymomonas mobilis Species 0.000 description 1
- 238000013019 agitation Methods 0.000 description 1
- 229910000147 aluminium phosphate Inorganic materials 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- 239000006227 byproduct Substances 0.000 description 1
- 230000000295 complement effect Effects 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 230000001627 detrimental effect Effects 0.000 description 1
- 230000006801 homologous recombination Effects 0.000 description 1
- 238000002744 homologous recombination Methods 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 230000004807 localization Effects 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 239000011736 potassium bicarbonate Substances 0.000 description 1
- 235000015497 potassium bicarbonate Nutrition 0.000 description 1
- 229910000028 potassium bicarbonate Inorganic materials 0.000 description 1
- TYJJADVDDVDEDZ-UHFFFAOYSA-M potassium hydrogencarbonate Chemical compound [K+].OC([O-])=O TYJJADVDDVDEDZ-UHFFFAOYSA-M 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 231100000241 scar Toxicity 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US84781306P | 2006-09-28 | 2006-09-28 | |
| US60/847,813 | 2006-09-28 | ||
| PCT/US2007/020950 WO2008133638A2 (en) | 2006-09-28 | 2007-09-28 | Xylitol synthesis mutant of xylose-utilizing zymomonas for ethanol production |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010504758A JP2010504758A (ja) | 2010-02-18 |
| JP2010504758A5 true JP2010504758A5 (https=) | 2010-10-07 |
| JP5346808B2 JP5346808B2 (ja) | 2013-11-20 |
Family
ID=39926224
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009530433A Expired - Fee Related JP5346808B2 (ja) | 2006-09-28 | 2007-09-28 | エタノール産生のためのキシロース資化性ザイモモナス(Zymomonas)のキシリトール合成変異体 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US7741119B2 (https=) |
| EP (1) | EP2066784B1 (https=) |
| JP (1) | JP5346808B2 (https=) |
| CN (1) | CN101861385B (https=) |
| BR (1) | BRPI0715282A2 (https=) |
| CA (1) | CA2661512C (https=) |
| ES (1) | ES2554805T3 (https=) |
| HU (1) | HUE026720T2 (https=) |
| PL (1) | PL2066784T3 (https=) |
| WO (1) | WO2008133638A2 (https=) |
Families Citing this family (90)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7781191B2 (en) * | 2005-04-12 | 2010-08-24 | E. I. Du Pont De Nemours And Company | Treatment of biomass to obtain a target chemical |
| EP2060632A1 (en) * | 2007-10-29 | 2009-05-20 | Technische Universität Berlin | Method of modifying a yeast cell for the production of ethanol |
| ATE554175T1 (de) * | 2007-10-30 | 2012-05-15 | Du Pont | Zymomonas mit erhöhter ethanolproduktion in einem medium mit konzentrierten zuckern und acetat |
| JP2011515107A (ja) * | 2008-03-27 | 2011-05-19 | イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー | 改善されたキシロース資化能を有するザイモモナス(Zymomonas) |
| BRPI0906241B8 (pt) * | 2008-03-27 | 2019-02-19 | Alliance Sustainable Energy | molécula de ácido nucleico, gene quimérico, vetor e método de transformação de uma célula bacteriana |
| US20100159521A1 (en) * | 2008-12-19 | 2010-06-24 | E. I. Du Pont De Nemours And Company | Ozone treatment of biomass to enhance enzymatic saccharification |
| US8247208B2 (en) | 2008-12-22 | 2012-08-21 | Alliance For Sustainable Energy Llc | Zymomonas with improved xylose utilization in stress conditions |
| US20110143408A1 (en) * | 2009-06-18 | 2011-06-16 | E. I. Du Pont De Nemours And Company | Zymomonas with improved arabinose utilization |
| CN102803649A (zh) | 2009-06-25 | 2012-11-28 | 国际壳牌研究有限公司 | 注水系统和方法 |
| CN102666870A (zh) | 2009-10-12 | 2012-09-12 | 纳幕尔杜邦公司 | 用于改善的抑制剂特征的生物质的氨预处理 |
| US8647850B2 (en) | 2009-12-23 | 2014-02-11 | E I Du Pont De Nemours And Company | Process for simultaneous saccharification and fermentation for production of ethanol |
| AU2010333801B2 (en) | 2009-12-23 | 2015-12-17 | Danisco Us Inc. | Methods for improving the efficiency of simultaneous saccharification and fermentation reactions |
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| EP2575432B1 (en) | 2010-06-02 | 2019-08-14 | Evolva, Inc. | Recombinant production of steviol glycosides |
| US9206448B2 (en) | 2010-06-18 | 2015-12-08 | Butamax Advanced Biofuels Llc | Extraction solvents derived from oil for alcohol removal in extractive fermentation |
| JP2013533742A (ja) | 2010-06-18 | 2013-08-29 | ビュータマックス・アドバンスド・バイオフューエルズ・エルエルシー | 抽出発酵におけるアルコール除去のための、油に由来する抽出溶媒 |
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| US8623623B2 (en) | 2010-06-29 | 2014-01-07 | E I Du Pont De Nemours And Company | Xylose utilization in recombinant Zymomonas |
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| WO2012047832A2 (en) | 2010-10-07 | 2012-04-12 | Shell Oil Company | Process for the production of alcohols from biomass |
| EP2635712B1 (en) | 2010-11-05 | 2014-07-02 | Shell Oil Company | Treating biomass to produce materials useful for biofuels |
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| US8609379B2 (en) | 2010-12-20 | 2013-12-17 | Shell Oil Company | Process for the production of alcohols from biomass |
| US20120196342A1 (en) | 2011-02-01 | 2012-08-02 | Rachel Ruizhen Chen | Industrial Applications of A Novel Aldo/Keto Reductase Of Zymomonas Mobilis |
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| EP3458599A1 (en) | 2016-05-16 | 2019-03-27 | Evolva SA | Production of steviol glycosides in recombinant hosts |
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| US10562874B2 (en) | 2016-11-01 | 2020-02-18 | Shell Oil Company | Process for the recovery of furfural |
| WO2018083338A1 (en) | 2016-11-07 | 2018-05-11 | Evolva Sa | Production of steviol glycosides in recombinant hosts |
| WO2018106656A1 (en) | 2016-12-06 | 2018-06-14 | Danisco Us Inc | Truncated lpmo enzymes and use thereof |
| WO2019074828A1 (en) | 2017-10-09 | 2019-04-18 | Danisco Us Inc | CELLOBIOSE DEHYDROGENASE VARIANTS AND METHODS OF USE |
| EP3972962A1 (en) | 2019-05-22 | 2022-03-30 | Shell Internationale Research Maatschappij B.V. | Process for the production of furfural |
| US11649470B2 (en) | 2019-07-19 | 2023-05-16 | ExxonMobil Technology and Engineering Company | Feed control in conversion of biomass into hydrocarbon fuels and chemicals |
| CN113444763B (zh) * | 2021-08-16 | 2022-11-08 | 农业部沼气科学研究所 | 树干毕赤酵母与运动发酵单胞菌混菌发酵葡萄糖和木糖产乙醇的方法 |
| CN120530199A (zh) | 2023-01-23 | 2025-08-22 | 国际壳牌研究有限公司 | 用于处理谷粒以产生可用于化学品和生物燃料的材料的方法 |
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|---|---|---|---|---|
| US5231020A (en) | 1989-03-30 | 1993-07-27 | Dna Plant Technology Corporation | Genetic engineering of novel plant phenotypes |
| US5843760A (en) | 1994-04-15 | 1998-12-01 | Midwest Research Institute | Single zymomonas mobilis strain for xylose and arabinose fermentation |
| US5514583A (en) | 1994-04-15 | 1996-05-07 | Midwest Research Institute | Recombinant zymomonas for pentose fermentation |
| US5712133A (en) | 1994-04-15 | 1998-01-27 | Midwest Research Institute | Pentose fermentation by recombinant zymomonas |
| AU2388295A (en) | 1994-04-15 | 1995-11-10 | Midwest Research Institute | Recombinant zymomonas for pentose fermentation |
| US7374939B1 (en) | 2000-05-01 | 2008-05-20 | Midwest Research Institute | Method of inactivation of an end product of energy metabolism in Zymomonas mobilis |
| AU4992601A (en) * | 2000-05-01 | 2001-11-12 | Midwest Research Inst | Stable zymomonas mobilis xylose and arabinose fermenting strains |
| US7223575B2 (en) | 2000-05-01 | 2007-05-29 | Midwest Research Institute | Zymomonas pentose-sugar fermenting strains and uses thereof |
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| US6566107B1 (en) | 2000-11-01 | 2003-05-20 | Midwest Research Institute | Recombinant Zymomonas mobilis with improved xylose utilization |
| US20040231060A1 (en) | 2003-03-07 | 2004-11-25 | Athenix Corporation | Methods to enhance the activity of lignocellulose-degrading enzymes |
| CN1600850A (zh) | 2003-09-23 | 2005-03-30 | 中国农业科学院生物技术研究所 | 运动发酵单胞菌工程菌及其应用 |
-
2007
- 2007-09-27 US US11/862,566 patent/US7741119B2/en not_active Expired - Fee Related
- 2007-09-28 JP JP2009530433A patent/JP5346808B2/ja not_active Expired - Fee Related
- 2007-09-28 ES ES07874067.7T patent/ES2554805T3/es active Active
- 2007-09-28 BR BRPI0715282-5A patent/BRPI0715282A2/pt active Search and Examination
- 2007-09-28 HU HUE07874067A patent/HUE026720T2/en unknown
- 2007-09-28 CN CN200780036026XA patent/CN101861385B/zh not_active Expired - Fee Related
- 2007-09-28 PL PL07874067T patent/PL2066784T3/pl unknown
- 2007-09-28 EP EP07874067.7A patent/EP2066784B1/en not_active Not-in-force
- 2007-09-28 WO PCT/US2007/020950 patent/WO2008133638A2/en not_active Ceased
- 2007-09-28 CA CA2661512A patent/CA2661512C/en not_active Expired - Fee Related
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