CN1953417B
(zh)
*
|
1996-09-04 |
2010-12-29 |
英特托拉斯技术公司 |
一种从用户站点向外部站点发布使用数据的方法
|
EP2081905B1
(en)
|
2006-07-28 |
2012-09-12 |
Boehringer Ingelheim International GmbH |
Sulfonyl compounds which modulate the cb2 receptor
|
AU2007287428B2
(en)
|
2006-08-24 |
2011-08-11 |
Astrazeneca Ab |
Morpholino pyrimidine derivatives useful in the treatment of proliferative disorders
|
CN101516839A
(zh)
|
2006-09-25 |
2009-08-26 |
贝林格尔.英格海姆国际有限公司 |
调节cb2受体的化合物
|
US7759344B2
(en)
*
|
2007-01-09 |
2010-07-20 |
Amgen Inc. |
Bis-aryl amide derivatives and methods of use
|
EP2118087B1
(en)
*
|
2007-02-06 |
2012-03-28 |
Novartis AG |
Pi 3-kinase inhibitors and methods of their use
|
JP5508260B2
(ja)
*
|
2007-07-09 |
2014-05-28 |
アストラゼネカ アクチボラグ |
mTORキナーゼおよび/またはP13Kに関連する病気に用いられるモルホリノピリミジン誘導体
|
KR20100031639A
(ko)
*
|
2007-07-09 |
2010-03-23 |
아스트라제네카 아베 |
증식성 질환의 치료용 삼중 치환된 피리미딘 유도체
|
JP5492092B2
(ja)
|
2007-11-07 |
2014-05-14 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
Cb2受容体を調節する化合物
|
WO2009094224A1
(en)
|
2008-01-25 |
2009-07-30 |
Millennium Pharmaceuticals, Inc. |
Thiophenes and their use as phosphatidylinositol 3-kinase (pi3k) inhibitors
|
CN101981003B
(zh)
|
2008-02-29 |
2014-07-02 |
伊沃泰克股份公司 |
酰胺化合物、组合物及其应用
|
EP2418207A1
(en)
*
|
2008-05-13 |
2012-02-15 |
Boehringer Ingelheim International GmbH |
Sulfone compounds which modulate the CB2 receptor
|
CA2721692C
(en)
|
2008-05-23 |
2014-01-14 |
Wyeth Llc |
Triazine compounds as p13 kinase and mtor inhibitors
|
EP2313399B1
(en)
|
2008-06-19 |
2014-05-28 |
Millennium Pharmaceuticals, Inc. |
Thiophene or thiazole derivatives and their use as pi3k inhibitors
|
JP5749162B2
(ja)
|
2008-07-10 |
2015-07-15 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
Cb2受容体を調節するスルホン化合物
|
AU2009276339B2
(en)
|
2008-07-31 |
2012-06-07 |
Genentech, Inc. |
Pyrimidine compounds, compositions and methods of use
|
US20110166135A1
(en)
|
2008-09-10 |
2011-07-07 |
Hiroshi Morimoto |
Aromatic nitrogen-containing 6-membered ring compounds and their use
|
WO2010033168A2
(en)
*
|
2008-09-18 |
2010-03-25 |
Renovis, Inc. |
Amide compounds, compositions and uses thereof
|
BRPI0919172A2
(pt)
|
2008-09-25 |
2015-12-15 |
Boehringer Ingelheim Int |
compostos os quais modulam seletivamente o receptor de cb2
|
TWI378933B
(en)
|
2008-10-14 |
2012-12-11 |
Daiichi Sankyo Co Ltd |
Morpholinopurine derivatives
|
US20110053923A1
(en)
|
2008-12-22 |
2011-03-03 |
Astrazeneca |
Chemical compounds 610
|
US9090601B2
(en)
|
2009-01-30 |
2015-07-28 |
Millennium Pharmaceuticals, Inc. |
Thiazole derivatives
|
US8796314B2
(en)
|
2009-01-30 |
2014-08-05 |
Millennium Pharmaceuticals, Inc. |
Heteroaryls and uses thereof
|
CN102395585A
(zh)
|
2009-01-30 |
2012-03-28 |
米伦纽姆医药公司 |
杂芳基化合物和其作为pi3k抑制剂的用途
|
WO2010103094A1
(en)
|
2009-03-13 |
2010-09-16 |
Cellzome Limited |
PYRIMIDINE DERIVATIVES AS mTOR INHIBITORS
|
WO2010120996A1
(en)
*
|
2009-04-17 |
2010-10-21 |
Wyeth Llc |
5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine compounds, their use as mtor kinase and pi3 kinase inhibitors, and their syntheses
|
WO2010120991A1
(en)
*
|
2009-04-17 |
2010-10-21 |
Wyeth Llc |
5, 6, 7, 8-tetrahydropyrido[4,3-d]pyrimidine compounds, their use as mtor, pi3, and hsmg-1 kinase inhibitors, and their syntheses
|
WO2010120998A1
(en)
*
|
2009-04-17 |
2010-10-21 |
Wyeth Llc |
Pyrimidine compounds, their use as mtor kinase and pi3 kinase inhibitors, and their syntheses
|
TW201103943A
(en)
*
|
2009-04-27 |
2011-02-01 |
Shionogi & Co |
Urea derivative having pi3k inhibitory activity
|
US8299103B2
(en)
|
2009-06-15 |
2012-10-30 |
Boehringer Ingelheim International Gmbh |
Compounds which selectively modulate the CB2 receptor
|
EP2443107B1
(en)
|
2009-06-16 |
2018-08-08 |
Boehringer Ingelheim International GmbH |
Azetidine 2 -carboxamide derivatives which modulate the cb2 receptor
|
GEP20156325B
(en)
|
2009-06-17 |
2015-07-10 |
Vertex Pharma |
Inhibitors of influenza viruses replication
|
SG176959A1
(en)
*
|
2009-06-24 |
2012-01-30 |
Genentech Inc |
Oxo-heterocycle fused pyrimidine compounds, compositions and methods of use
|
WO2011037795A1
(en)
|
2009-09-22 |
2011-03-31 |
Boehringer Ingelheim International Gmbh |
Compounds which selectively modulate the cb2 receptor
|
KR20120115237A
(ko)
|
2009-10-30 |
2012-10-17 |
어리어드 파마슈티칼스, 인코포레이티드 |
암 치료 방법 및 조성물
|
KR101447789B1
(ko)
|
2009-11-12 |
2014-10-06 |
에프. 호프만-라 로슈 아게 |
N-7 치환된 퓨린 및 피라졸로피리미딘 화합물, 조성물 및 사용 방법
|
KR101469334B1
(ko)
|
2009-11-12 |
2014-12-04 |
에프. 호프만-라 로슈 아게 |
N-9-치환된 퓨린 화합물, 조성물 및 사용 방법
|
US9315491B2
(en)
|
2009-12-28 |
2016-04-19 |
Development Center For Biotechnology |
Pyrimidine compounds as mTOR and PI3K inhibitors
|
WO2011088015A1
(en)
|
2010-01-15 |
2011-07-21 |
Boehringer Ingelheim International Gmbh |
Compounds which modulate the cb2 receptor
|
ES2535116T3
(es)
|
2010-03-04 |
2015-05-05 |
Cellzome Limited |
Derivados de urea sustituida con morfolino como inhibidores de mtor
|
US8329735B2
(en)
|
2010-03-05 |
2012-12-11 |
Boehringer Ingelheim International Gmbh |
Tetrazole compounds which selectively modulate the CB2 receptor
|
SA111320519B1
(ar)
|
2010-06-11 |
2014-07-02 |
Astrazeneca Ab |
مركبات بيريميدينيل للاستخدام كمثبطات atr
|
EP2595959B1
(en)
|
2010-07-22 |
2015-11-04 |
Boehringer Ingelheim International GmbH |
Sulfonyl compounds which modulate the cb2 receptor
|
EP2603216A4
(en)
|
2010-08-11 |
2013-12-18 |
Millennium Pharm Inc |
HETEROARYLE AND USES THEREOF
|
US9062038B2
(en)
|
2010-08-11 |
2015-06-23 |
Millennium Pharmaceuticals, Inc. |
Heteroaryls and uses thereof
|
CN103153300A
(zh)
|
2010-08-11 |
2013-06-12 |
米伦纽姆医药公司 |
杂芳基化合物和其用途
|
JP5998145B2
(ja)
|
2010-10-01 |
2016-09-28 |
ノバルティス アーゲー |
ピリミジン誘導体の製造プロセス
|
SG189396A1
(en)
|
2010-10-13 |
2013-05-31 |
Millennium Pharm Inc |
Heteroaryls and uses thereof
|
US8440662B2
(en)
|
2010-10-31 |
2013-05-14 |
Endo Pharmaceuticals, Inc. |
Substituted quinazoline and pyrido-pyrimidine derivatives
|
US20140163023A1
(en)
|
2011-04-04 |
2014-06-12 |
Cellzome Limited |
Dihydropyrrolo pyrimidine derivatives as mtor inhibitors
|
CN102887867B
(zh)
*
|
2011-07-21 |
2015-04-15 |
中国科学院上海药物研究所 |
一类三嗪类化合物、该化合物的制备方法及其用途
|
EP2736900A1
(en)
*
|
2011-07-26 |
2014-06-04 |
Grünenthal GmbH |
Substituted heteroaromatic pyrazole-containing carboxamide and urea derivatives as vanilloid receptor ligands
|
UA118010C2
(uk)
|
2011-08-01 |
2018-11-12 |
Вертекс Фармасьютікалз Інкорпорейтед |
Інгібітори реплікації вірусів грипу
|
DK2753606T3
(en)
*
|
2011-09-02 |
2017-10-02 |
Purdue Pharma Lp |
PYRIMIDINES AS SODIUM CHANNEL BLOCKERS
|
AU2012311458B2
(en)
|
2011-09-21 |
2016-02-04 |
Cellzome Limited |
Morpholino substituted urea or carbamate derivatives as mTOR inhibitors
|
US9242993B2
(en)
|
2011-10-07 |
2016-01-26 |
Cellzome Limited |
Morpholino substituted bicyclic pyrimidine urea or carbamate derivatives as mTOR inhibitors
|
CA2868392A1
(en)
|
2012-05-23 |
2013-11-28 |
Estelle DOUDEMENT |
Compositions and methods of obtaining and using endoderm and hepatocyte cells
|
EP2803668A1
(en)
|
2013-05-17 |
2014-11-19 |
Boehringer Ingelheim International Gmbh |
Novel (cyano-dimethyl-methyl)-isoxazoles and -[1,3,4]thiadiazoles
|
US9296727B2
(en)
|
2013-10-07 |
2016-03-29 |
Vertex Pharmaceuticals Incorporated |
Methods of regioselective synthesis of 2,4-disubstituted pyrimidines
|
EP3421468B1
(en)
|
2013-11-13 |
2020-11-04 |
Vertex Pharmaceuticals Incorporated |
Methods of preparing inhibitors of influenza viruses replication
|
RS59144B1
(sr)
|
2013-11-13 |
2019-09-30 |
Vertex Pharma |
Inhibitori replikacije virusa influence
|
ES2788700T3
(es)
*
|
2014-05-21 |
2020-10-22 |
Allergan Inc |
Derivados de imidazol como moduladores del receptor de péptido formilado
|
SG11201700777VA
(en)
|
2014-08-04 |
2017-02-27 |
Nuevolution As |
Optionally fused heterocyclyl-substituted derivatives of pyrimidine useful for the treatment of inflammatory, metabolic, oncologic and autoimmune diseases
|
WO2016183116A1
(en)
|
2015-05-13 |
2016-11-17 |
Vertex Pharmaceuticals Incorporated |
Methods of preparing inhibitors of influenza viruses replication
|
WO2016183120A1
(en)
|
2015-05-13 |
2016-11-17 |
Vertex Pharmaceuticals Incorporated |
Inhibitors of influenza viruses replication
|
TW201825465A
(zh)
|
2016-09-23 |
2018-07-16 |
美商基利科學股份有限公司 |
磷脂醯肌醇3-激酶抑制劑
|
TW201815787A
(zh)
|
2016-09-23 |
2018-05-01 |
美商基利科學股份有限公司 |
磷脂醯肌醇3-激酶抑制劑
|
TW201813963A
(zh)
|
2016-09-23 |
2018-04-16 |
美商基利科學股份有限公司 |
磷脂醯肌醇3-激酶抑制劑
|
EP3630116B1
(en)
|
2017-05-26 |
2024-05-01 |
The Board Of Regents Of The University Of Texas System |
Tetrahydropyrido[4,3-d]pyrimidine inhibitors of atr kinase
|
LT3651768T
(lt)
|
2017-07-13 |
2024-04-25 |
Board Of Regents, The University Of Texas System |
Heterocikliniai atr kinazės inhibitoriai
|
CN111886224A
(zh)
|
2017-08-17 |
2020-11-03 |
德州大学系统董事会 |
Atr激酶的杂环抑制剂
|
CN112218631B
(zh)
|
2018-03-16 |
2023-12-22 |
德州大学系统董事会 |
Atr激酶的杂环抑制剂
|
MX2022007265A
(es)
|
2019-12-20 |
2022-09-09 |
Nuevolution As |
Compuestos activos frente a receptores nucleares.
|
US11780843B2
(en)
|
2020-03-31 |
2023-10-10 |
Nuevolution A/S |
Compounds active towards nuclear receptors
|
EP4126875A1
(en)
|
2020-03-31 |
2023-02-08 |
Nuevolution A/S |
Compounds active towards nuclear receptors
|