|
WO2001007657A1
(en)
*
|
1999-07-27 |
2001-02-01 |
Phylos, Inc. |
Peptide acceptor ligation methods
|
|
CA2397091A1
(en)
|
2000-01-11 |
2001-07-19 |
Markus Schweitzer |
Biomolecules having multiple attachment moieties for binding to a substrate surface
|
|
AU2001262152A1
(en)
*
|
2000-03-31 |
2001-10-08 |
Memorec Stoffel Gmbh |
Method for extracting nucleic acids
|
|
US7410761B2
(en)
*
|
2000-05-19 |
2008-08-12 |
Proteonova, Inc. |
System for rapid identification and selection of nucleic acids and polypeptides, and method thereof
|
|
US20040229271A1
(en)
*
|
2000-05-19 |
2004-11-18 |
Williams Richard B. |
Compositions and methods for the identification and selection of nucleic acids and polypeptides
|
|
US6962781B1
(en)
*
|
2000-05-19 |
2005-11-08 |
Proteonova, Inc. |
In vitro evolution of nucleic acids and encoded polypeptide
|
|
AU2001295005A1
(en)
*
|
2000-08-11 |
2002-02-25 |
Nanogen, Inc. |
Macromolecules having hydrazide attachment moieties and reagents for their production
|
|
US7129229B2
(en)
|
2000-08-11 |
2006-10-31 |
Nanogen Recognomics Gmbh |
Hydrazide building blocks and hydrazide modified biomolecules
|
|
JP4963142B2
(ja)
*
|
2000-12-14 |
2012-06-27 |
学校法人慶應義塾 |
遺伝子型と表現型の対応付け分子とその構成要素、および対応付け分子の製造方法と利用方法
|
|
US20060234231A1
(en)
*
|
2001-06-20 |
2006-10-19 |
Nuevolution A/S |
Microarrays displaying encoded molecules
|
|
EP1401850A1
(en)
|
2001-06-20 |
2004-03-31 |
Nuevolution A/S |
Nucleoside derivatives for library preparation
|
|
US6893822B2
(en)
|
2001-07-19 |
2005-05-17 |
Nanogen Recognomics Gmbh |
Enzymatic modification of a nucleic acid-synthetic binding unit conjugate
|
|
WO2003012146A1
(en)
*
|
2001-07-31 |
2003-02-13 |
Phylos, Inc. |
Modular assembly of nucleic acid-protein fusion multimers
|
|
DE10147074A1
(de)
*
|
2001-09-25 |
2003-05-08 |
Beru Ag |
Verfahren zum Betreiben einer aus mehreren Heizelementen bestehenden mehrstufigen elektrischen Heizung
|
|
AU2002356984A1
(en)
*
|
2001-11-16 |
2003-06-10 |
Proteonova, Inc. |
Selection and evolution of nucleic acids and polypeptides
|
|
US7125669B2
(en)
*
|
2001-11-27 |
2006-10-24 |
Compound Therapeutics, Inc. |
Solid-phase immobilization of proteins and peptides
|
|
DE20200926U1
(de)
*
|
2002-01-23 |
2002-04-18 |
Hegenscheidt-MFD GmbH & Co. KG, 41812 Erkelenz |
Festwalzgerät einer Festwalzmaschine für Kurbelwellen
|
|
AU2003218629A1
(en)
*
|
2002-03-15 |
2003-09-29 |
Nuevolution A/S |
A building block forming a c-c or a c-hetero atom bond uponreaction
|
|
EP1487978B1
(en)
*
|
2002-03-15 |
2008-11-19 |
Nuevolution A/S |
An improved method for synthesising templated molecules
|
|
US20050221318A1
(en)
*
|
2002-03-15 |
2005-10-06 |
Gouliaev Alex H |
Building block forming a c-c bond upon reaction
|
|
AU2003214033A1
(en)
*
|
2002-03-15 |
2003-09-29 |
Nuevolution A/S |
A building block capable of transferring a functional entity
|
|
WO2004013070A2
(en)
|
2002-08-01 |
2004-02-12 |
Nuevolution A/S |
Multi-step synthesis of templated molecules
|
|
AU2003256857A1
(en)
*
|
2002-08-08 |
2004-02-25 |
Dharmacon, Inc. |
Short interfering rnas having a hairpin structure containing a non-nucleotide loop
|
|
PT2348125T
(pt)
|
2002-10-30 |
2017-08-29 |
Nuevolution As |
Método para a síntese de um complexo bifuncional
|
|
AU2003291964A1
(en)
|
2002-12-19 |
2004-07-14 |
Nuevolution A/S |
Quasirandom structure and function guided synthesis methods
|
|
US20070026397A1
(en)
*
|
2003-02-21 |
2007-02-01 |
Nuevolution A/S |
Method for producing second-generation library
|
|
EP1597394A2
(en)
*
|
2003-02-21 |
2005-11-23 |
Nuevolution A/S |
A method for obtaining structural information about an encoded molecule
|
|
DE602004019764D1
(de)
*
|
2003-03-20 |
2009-04-16 |
Nuevolution As |
Ligationsvermittelnde codierung von kleinen molekülen
|
|
WO2004110964A2
(en)
*
|
2003-06-16 |
2004-12-23 |
Nuevolution A/S |
Encoded molecules by translation (emt)
|
|
US20050095627A1
(en)
*
|
2003-09-03 |
2005-05-05 |
The Salk Institute For Biological Studies |
Multiple antigen detection assays and reagents
|
|
EP1670939B1
(en)
*
|
2003-09-18 |
2009-11-04 |
Nuevolution A/S |
A method for obtaining structural information concerning an encoded molecule and method for selecting compounds
|
|
CN1906307B
(zh)
*
|
2003-11-20 |
2011-08-24 |
圣诺菲·帕斯图尔公司 |
纯化百日咳毒素的方法及其中有用的肽
|
|
CN1946417A
(zh)
|
2003-12-05 |
2007-04-11 |
阿德内克休斯治疗公司 |
2型血管内皮生长因子受体的抑制剂
|
|
AU2004314705A1
(en)
*
|
2003-12-12 |
2005-08-11 |
Proteonova, Inc. |
System and methods for nucleic acid and polypeptide selection
|
|
EP1723255B1
(en)
*
|
2004-02-17 |
2010-12-29 |
Nuevolution A/S |
Method for enrichment involving elimination by mismatch hybridisation
|
|
DE602005017370D1
(de)
*
|
2004-03-22 |
2009-12-10 |
Nuevolution As |
Ligationscodierung unter verwendung von oligonukleotidbausteinen
|
|
CA2467321A1
(en)
*
|
2004-05-14 |
2005-11-14 |
Paul J. Santerre |
Polymeric coupling agents and pharmaceutically-active polymers made therefrom
|
|
WO2006041194A1
(ja)
|
2004-10-15 |
2006-04-20 |
Japan Science And Technology Agency |
ｍＲＮＡ－ピューロマイシン－タンパク質連結体作製用リンカー
|
|
EP2261257B1
(en)
|
2005-01-12 |
2018-07-11 |
Proteonova, Inc. |
Method for making targeted therapeutic agents
|
|
US10206998B2
(en)
|
2005-01-12 |
2019-02-19 |
Proteonova, Inc. |
Modular targeted therapeutic agents and methods of making same
|
|
EP1951890A4
(en)
|
2005-11-16 |
2009-06-24 |
Ambrx Inc |
PROCESSES AND COMPOSITIONS WITH NON-NATURAL AMINO ACIDS
|
|
HUE056836T2
(hu)
|
2005-12-01 |
2022-03-28 |
Nuevolution As |
Enzimatikus kódolási eljárások nagy könyvtárak hatékony szintéziséhez
|
|
US7749957B2
(en)
|
2006-04-06 |
2010-07-06 |
E.I. Du Pont De Nemours And Company |
Clay-binding peptides and methods of use
|
|
CA2670471A1
(en)
|
2006-11-22 |
2008-06-05 |
Adnexus, A Bristol-Myers Squibb R&D Company (A Delaware Corporation) |
Targeted therapeutics based on engineered proteins for tyrosine kinases receptors, including igf-ir
|
|
AU2008216303A1
(en)
|
2007-02-12 |
2008-08-21 |
Proteonova, Inc. |
Generation of library of soluble random polypeptides linked to mRNA
|
|
US7951559B2
(en)
*
|
2007-07-25 |
2011-05-31 |
E.I. Du Pont De Nemours And Company |
Recombinant peptide production using a cross-linkable solubility tag
|
|
US7678883B2
(en)
*
|
2007-07-25 |
2010-03-16 |
E.I. Du Pont De Nemours And Company |
Solubility tags for the expression and purification of bioactive peptides
|
|
US7829311B2
(en)
|
2007-07-25 |
2010-11-09 |
E.I. Du Pont De Nemours And Company |
Ketosteroid isomerase inclusion body tag engineered to be acid-resistant by replacing aspartates with glutamate
|
|
US7794963B2
(en)
|
2007-11-02 |
2010-09-14 |
E.I. Du Pont De Nemours And Company |
Use of tetracysteine tags in fluorescence-activated cell sorting analysis of prokaryotic cells producing peptides or proteins
|
|
US8883146B2
(en)
|
2007-11-30 |
2014-11-11 |
Abbvie Inc. |
Protein formulations and methods of making same
|
|
TWI543768B
(zh)
|
2007-11-30 |
2016-08-01 |
艾伯維生物技術有限責任公司 |
蛋白質調配物及製造其之方法
|
|
CN102007145A
(zh)
|
2008-02-14 |
2011-04-06 |
百时美施贵宝公司 |
基于结合egfr的工程化蛋白质的靶向治疗剂
|
|
EP2283132B1
(en)
*
|
2008-05-02 |
2016-10-26 |
Epicentre Technologies Corporation |
Selective 5' ligation tagging of rna
|
|
PL2274331T3
(pl)
|
2008-05-02 |
2014-04-30 |
Novartis Ag |
Ulepszone cząsteczki wiążące oparte na fibronektynie i ich zastosowanie
|
|
PE20091931A1
(es)
|
2008-05-22 |
2009-12-31 |
Bristol Myers Squibb Co |
Proteinas de dominio de armazon basadas en fibronectina multivalentes
|
|
EP3629022A1
(en)
|
2008-07-25 |
2020-04-01 |
Richard W. Wagner |
Protein screening methods
|
|
MX2011003381A
(es)
*
|
2008-09-30 |
2011-04-21 |
Abbott Lab |
Metodo mejorado para despliegue de arn.
|
|
TWI496582B
(zh)
|
2008-11-24 |
2015-08-21 |
必治妥美雅史谷比公司 |
雙重專一性之ｅｇｆｒ／ｉｇｆｉｒ結合分子
|
|
US20100158822A1
(en)
|
2008-12-18 |
2010-06-24 |
E .I. Du Pont De Nemours And Company |
Peptides that bind to silica-coated particles
|
|
US20100158846A1
(en)
*
|
2008-12-18 |
2010-06-24 |
E. I. Du Pont De Nemours And Company |
Hair-binding peptides
|
|
US8287845B2
(en)
*
|
2008-12-18 |
2012-10-16 |
E I Du Pont De Nemours And Company |
Hair-binding peptides
|
|
US20100158837A1
(en)
|
2008-12-18 |
2010-06-24 |
E. I. Du Pont De Nemours And Company |
Iron oxide-binding peptides
|
|
US20100247590A1
(en)
*
|
2009-03-30 |
2010-09-30 |
Johnson & Johnson |
Peptide-Based Systems For Delivery Of Cosmetic Agents
|
|
US8481678B2
(en)
|
2009-03-30 |
2013-07-09 |
E I Du Pont De Nemours And Company |
Peptide-based tooth whitening reagents
|
|
JP5733784B2
(ja)
*
|
2009-09-24 |
2015-06-10 |
国立大学法人埼玉大学 |
ｃＤＮＡ／ｍＲＮＡ−タンパク質連結体の効率的合成法
|
|
WO2011051327A2
(en)
|
2009-10-30 |
2011-05-05 |
Novartis Ag |
Small antibody-like single chain proteins
|
|
WO2011051466A1
(en)
|
2009-11-02 |
2011-05-05 |
Novartis Ag |
Anti-idiotypic fibronectin-based binding molecules and uses thereof
|
|
WO2011092233A1
(en)
|
2010-01-29 |
2011-08-04 |
Novartis Ag |
Yeast mating to produce high-affinity combinations of fibronectin-based binders
|
|
JP2013519869A
(ja)
|
2010-02-10 |
2013-05-30 |
ノバルティス アーゲー |
筋肉成長のための方法および化合物
|
|
WO2011126370A1
(en)
*
|
2010-04-09 |
2011-10-13 |
Universiteit Utrecht Holding B.V. |
Recombinant multimeric influenza proteins
|
|
WO2011127933A1
(en)
|
2010-04-16 |
2011-10-20 |
Nuevolution A/S |
Bi-functional complexes and methods for making and using such complexes
|
|
TW201138808A
(en)
|
2010-05-03 |
2011-11-16 |
Bristol Myers Squibb Co |
Serum albumin binding molecules
|
|
ES2573108T3
(es)
|
2010-05-26 |
2016-06-06 |
Bristol-Myers Squibb Company |
Proteínas de armazón a base de fibronectina que tienen estabilidad mejorada
|
|
CN107903321A
(zh)
|
2010-07-30 |
2018-04-13 |
诺华有限公司 |
纤连蛋白摇篮分子和其库
|
|
DE102010056289A1
(de)
|
2010-12-24 |
2012-06-28 |
Geneart Ag |
Verfahren zur Herstellung von Leseraster-korrekten Fragment-Bibliotheken
|
|
ES2873375T3
(es)
|
2011-03-15 |
2021-11-03 |
X Body Inc |
Métodos de cribado de anticuerpos
|
|
PT3415619T
(pt)
|
2011-04-28 |
2021-03-22 |
Univ Leland Stanford Junior |
Identificação de polinucleótidos associados a uma amostra
|
|
CA2843955A1
(en)
|
2011-08-01 |
2013-02-07 |
The General Hospital Corporation |
Protein and peptide libraries
|
|
AU2012323316B2
(en)
|
2011-10-11 |
2017-08-10 |
Viela Bio, Inc. |
CD40L-specific Tn3-derived scaffolds and methods of use thereof
|
|
CN104105708B
(zh)
|
2011-12-05 |
2018-04-03 |
X博迪生物科学公司 |
PDGF受体β结合多肽
|
|
JP6020865B2
(ja)
*
|
2013-03-13 |
2016-11-02 |
国立大学法人 東京大学 |
核酸リンカー
|
|
ES2920601T3
(es)
|
2013-06-28 |
2022-08-05 |
X Body Inc |
Descubrimiento de antígenos objetivo, cribados fenotípicos y uso de los mismos para la identificación de epítopos objetivo específicos de células objetivo
|
|
CN103382579B
(zh)
*
|
2013-07-06 |
2015-10-21 |
中国科学院成都生物研究所 |
一种体外筛选多肽的方法
|
|
WO2015042528A1
(en)
|
2013-09-23 |
2015-03-26 |
X-Body Biosciences, Inc. |
Methods and compositions for generation of binding agents against cell surface antigens
|
|
US20150184214A1
(en)
*
|
2013-12-31 |
2015-07-02 |
Roche Nimblegen, Inc. |
Enrichment of full length oligonucleotides via transcription/translation mediated purification
|
|
US10421958B2
(en)
|
2014-02-05 |
2019-09-24 |
Molecular Templates, Inc. |
Methods of screening, selecting, and identifying cytotoxic recombinant polypeptides based on an interim diminution of ribotoxicity
|
|
EP3129401B1
(en)
|
2014-03-20 |
2019-06-12 |
Bristol-Myers Squibb Company |
Serum albumin-binding fibronectin type iii domains
|
|
JP6478392B2
(ja)
*
|
2014-12-26 |
2019-03-06 |
国立研究開発法人産業技術総合研究所 |
核酸リンカー
|
|
EP3842451A1
(en)
|
2015-03-12 |
2021-06-30 |
MedImmune, LLC |
Method of purifying albumin-fusion proteins
|
|
EP3708580B1
(en)
|
2015-09-23 |
2023-11-01 |
Bristol-Myers Squibb Company |
Fast-off rate serum albumin binding fibronectin type iii domains
|
|
AU2017259794B2
(en)
|
2016-05-02 |
2023-04-13 |
Encodia, Inc. |
Macromolecule analysis employing nucleic acid encoding
|
|
EP3472355A4
(en)
|
2016-06-15 |
2020-07-29 |
Genecapture, Inc. |
COMPOSITIONS, METHODS AND DEVICES INCLUDING ROD LOOP MOLECULES-SENSORS
|
|
WO2018005559A1
(en)
|
2016-06-27 |
2018-01-04 |
Juno Therapeutics, Inc. |
Method of identifying peptide epitopes, molecules that bind such epitopes and related uses
|
|
MA45491A
(fr)
|
2016-06-27 |
2019-05-01 |
Juno Therapeutics Inc |
Épitopes à restriction cmh-e, molécules de liaison et procédés et utilisations associés
|
|
CA3057419A1
(en)
|
2017-03-21 |
2018-09-27 |
Fujifilm Corporation |
Peptide compound and method for producing same, composition for screening use, and method for selecting peptide compound
|
|
MX2020004559A
(es)
*
|
2017-10-31 |
2020-10-05 |
Encodia Inc |
Kits para análisis utilizando codificación y/o etiqueta de ácido nucleico.
|
|
RU2020112854A
(ru)
|
2017-11-30 |
2021-12-30 |
Арракис Терапьютикс, Инк. |
Фотозонды, связывающие нуклеиновые кислоты, и способы их применения
|
|
CN111971292B
(zh)
|
2018-02-02 |
2024-12-13 |
波纹疗法公司 |
包含类固醇二聚体的玻璃制剂及其用途
|
|
TWI830718B
(zh)
*
|
2018-02-09 |
2024-02-01 |
日商住友化學股份有限公司 |
核酸分子之製造方法
|
|
EP3778914A4
(en)
*
|
2018-03-30 |
2022-01-19 |
Sumitomo Chemical Company, Ltd. |
Method for producing single-strand rna
|
|
WO2019236644A1
(en)
*
|
2018-06-05 |
2019-12-12 |
Arrakis Therapeutics, Inc. |
Encoded libraries and methods of use for screening nucleic acid targets
|
|
WO2020154815A1
(en)
|
2019-02-01 |
2020-08-06 |
Ripple Therapeutics Corporation |
Crystalline forms of dexamethasone dimers and uses thereof
|
|
WO2021024041A1
(en)
|
2019-08-07 |
2021-02-11 |
Ripple Therapeutics Corporation |
Controlled release drug dimers
|
|
MX2022013665A
(es)
|
2020-05-01 |
2022-11-30 |
Ripple Therapeutics Corp |
Composiciones y metodos heterodimeros para el tratamiento de trastornos oculares.
|