JP2017522323A5 - - Google Patents

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Publication number
JP2017522323A5
JP2017522323A5 JP2017502695A JP2017502695A JP2017522323A5 JP 2017522323 A5 JP2017522323 A5 JP 2017522323A5 JP 2017502695 A JP2017502695 A JP 2017502695A JP 2017502695 A JP2017502695 A JP 2017502695A JP 2017522323 A5 JP2017522323 A5 JP 2017522323A5
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JP
Japan
Prior art keywords
rna
cell
repeat sequence
moiety
module
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JP2017502695A
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English (en)
Japanese (ja)
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JP6461306B2 (ja
JP2017522323A (ja
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Priority claimed from PCT/US2015/040902 external-priority patent/WO2016011348A1/en
Publication of JP2017522323A publication Critical patent/JP2017522323A/ja
Publication of JP2017522323A5 publication Critical patent/JP2017522323A5/ja
Application granted granted Critical
Publication of JP6461306B2 publication Critical patent/JP6461306B2/ja
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JP2017502695A 2014-07-18 2015-07-17 インサイチュで自己組織化した、毒性のあるrna阻害剤 Active JP6461306B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462026266P 2014-07-18 2014-07-18
US62/026,266 2014-07-18
PCT/US2015/040902 WO2016011348A1 (en) 2014-07-18 2015-07-17 Toxic rna inhibitors self-assembled in situ

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2018241478A Division JP2019068831A (ja) 2014-07-18 2018-12-25 インサイチュで自己組織化した、毒性のあるrna阻害剤

Publications (3)

Publication Number Publication Date
JP2017522323A JP2017522323A (ja) 2017-08-10
JP2017522323A5 true JP2017522323A5 (https=) 2018-08-30
JP6461306B2 JP6461306B2 (ja) 2019-01-30

Family

ID=55079084

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2017502695A Active JP6461306B2 (ja) 2014-07-18 2015-07-17 インサイチュで自己組織化した、毒性のあるrna阻害剤
JP2018241478A Pending JP2019068831A (ja) 2014-07-18 2018-12-25 インサイチュで自己組織化した、毒性のあるrna阻害剤

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2018241478A Pending JP2019068831A (ja) 2014-07-18 2018-12-25 インサイチュで自己組織化した、毒性のあるrna阻害剤

Country Status (9)

Country Link
US (2) US10220031B2 (https=)
EP (1) EP3169404A4 (https=)
JP (2) JP6461306B2 (https=)
CN (1) CN106714908A (https=)
AU (1) AU2015289524A1 (https=)
CA (1) CA2955428A1 (https=)
IL (1) IL250113A0 (https=)
SG (1) SG11201700387QA (https=)
WO (1) WO2016011348A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2015289524A1 (en) * 2014-07-18 2017-02-02 The Scripps Research Institute Toxic RNA inhibitors self-assembled in situ
WO2018098297A1 (en) * 2016-11-28 2018-05-31 The Scripps Research Institute Precise small molecule recognition of a toxic cug rna repeat expansion
RU2020112854A (ru) 2017-11-30 2021-12-30 Арракис Терапьютикс, Инк. Фотозонды, связывающие нуклеиновые кислоты, и способы их применения
US12571031B2 (en) 2020-09-02 2026-03-10 Promega Corporation Nucleic acid modifying reagents and uses thereof
JP2025507917A (ja) * 2022-03-01 2025-03-21 プロメガ コーポレイション 核酸架橋試薬及びその使用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9150612B2 (en) * 2007-02-23 2015-10-06 The Research Foundation Of State University Of New York RNA targeting compounds and methods for making and using same
WO2012050896A2 (en) * 2010-09-29 2012-04-19 Kansas State University Research Foundation Protease selective supramolecular assemblies
US20140050778A1 (en) * 2010-12-28 2014-02-20 University Of Rochester Nucleic acid binding compounds, methods of making, and use thereof
US9610362B2 (en) * 2012-03-16 2017-04-04 Valerion Therapeutics, Llc Antisense conjugates for decreasing expression of DMPK
US9550769B2 (en) * 2012-08-30 2017-01-24 The Scripps Research Institute Small molecules targeting repeat r(CGG) sequences
AU2015289524A1 (en) * 2014-07-18 2017-02-02 The Scripps Research Institute Toxic RNA inhibitors self-assembled in situ

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