JP2010180243A5 - - Google Patents

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Publication number
JP2010180243A5
JP2010180243A5 JP2010098845A JP2010098845A JP2010180243A5 JP 2010180243 A5 JP2010180243 A5 JP 2010180243A5 JP 2010098845 A JP2010098845 A JP 2010098845A JP 2010098845 A JP2010098845 A JP 2010098845A JP 2010180243 A5 JP2010180243 A5 JP 2010180243A5
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JP
Japan
Prior art keywords
compound
acid
formula
chemical formula
residue
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP2010098845A
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English (en)
Japanese (ja)
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JP5503393B2 (ja
JP2010180243A (ja
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Publication date
Priority claimed from DE19955190A external-priority patent/DE19955190A1/de
Application filed filed Critical
Publication of JP2010180243A publication Critical patent/JP2010180243A/ja
Publication of JP2010180243A5 publication Critical patent/JP2010180243A5/ja
Application granted granted Critical
Publication of JP5503393B2 publication Critical patent/JP5503393B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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JP2010098845A 1999-11-16 2010-04-22 3,3−ジフェニルプロピルアミン類の新規誘導体の安定な塩 Expired - Lifetime JP5503393B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19955190A DE19955190A1 (de) 1999-11-16 1999-11-16 Stabile Salze neuartiger Derivate von 3,3-Diphenylpropylaminen
DE19955190.1 1999-11-16

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2007042774A Division JP2007137895A (ja) 1999-11-16 2007-02-22 3,3−ジフェニルプロピルアミン類の新規誘導体の安定な塩

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2013229622A Division JP5717824B2 (ja) 1999-11-16 2013-11-05 3,3−ジフェニルプロピルアミン類の新規誘導体の安定な塩

Publications (3)

Publication Number Publication Date
JP2010180243A JP2010180243A (ja) 2010-08-19
JP2010180243A5 true JP2010180243A5 (enExample) 2011-09-08
JP5503393B2 JP5503393B2 (ja) 2014-05-28

Family

ID=7929277

Family Applications (6)

Application Number Title Priority Date Filing Date
JP2001537950A Expired - Lifetime JP4083431B2 (ja) 1999-11-16 2000-11-15 3,3−ジフェニルプロピルアミン類の新規誘導体の安定な塩
JP2007042774A Pending JP2007137895A (ja) 1999-11-16 2007-02-22 3,3−ジフェニルプロピルアミン類の新規誘導体の安定な塩
JP2010098844A Expired - Lifetime JP5650924B2 (ja) 1999-11-16 2010-04-22 3,3−ジフェニルプロピルアミン類の新規誘導体の安定な塩
JP2010098845A Expired - Lifetime JP5503393B2 (ja) 1999-11-16 2010-04-22 3,3−ジフェニルプロピルアミン類の新規誘導体の安定な塩
JP2011096911A Expired - Lifetime JP5290351B2 (ja) 1999-11-16 2011-04-25 3,3−ジフェニルプロピルアミン類の新規誘導体の安定な塩
JP2013229622A Expired - Lifetime JP5717824B2 (ja) 1999-11-16 2013-11-05 3,3−ジフェニルプロピルアミン類の新規誘導体の安定な塩

Family Applications Before (3)

Application Number Title Priority Date Filing Date
JP2001537950A Expired - Lifetime JP4083431B2 (ja) 1999-11-16 2000-11-15 3,3−ジフェニルプロピルアミン類の新規誘導体の安定な塩
JP2007042774A Pending JP2007137895A (ja) 1999-11-16 2007-02-22 3,3−ジフェニルプロピルアミン類の新規誘導体の安定な塩
JP2010098844A Expired - Lifetime JP5650924B2 (ja) 1999-11-16 2010-04-22 3,3−ジフェニルプロピルアミン類の新規誘導体の安定な塩

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2011096911A Expired - Lifetime JP5290351B2 (ja) 1999-11-16 2011-04-25 3,3−ジフェニルプロピルアミン類の新規誘導体の安定な塩
JP2013229622A Expired - Lifetime JP5717824B2 (ja) 1999-11-16 2013-11-05 3,3−ジフェニルプロピルアミン類の新規誘導体の安定な塩

Country Status (30)

Country Link
US (1) US6858650B1 (enExample)
EP (3) EP1690536B1 (enExample)
JP (6) JP4083431B2 (enExample)
KR (2) KR100536095B1 (enExample)
CN (1) CN1215045C (enExample)
AT (3) ATE337293T1 (enExample)
AU (1) AU778132B2 (enExample)
BR (1) BRPI0015610C1 (enExample)
CA (1) CA2389749C (enExample)
CY (2) CY1106204T1 (enExample)
CZ (2) CZ302497B6 (enExample)
DE (5) DE19955190A1 (enExample)
DK (3) DK1690536T3 (enExample)
EA (1) EA005588B1 (enExample)
ES (3) ES2236032T7 (enExample)
GE (1) GEP20084430B (enExample)
HK (1) HK1045148B (enExample)
HU (2) HU228197B1 (enExample)
IL (2) IL149567A0 (enExample)
IS (2) IS2124B (enExample)
MX (1) MXPA02004603A (enExample)
NO (2) NO323920B1 (enExample)
NZ (1) NZ519230A (enExample)
PL (1) PL201422B1 (enExample)
PT (3) PT1481964E (enExample)
SI (3) SI1481964T1 (enExample)
SK (3) SK288384B6 (enExample)
UA (2) UA73324C2 (enExample)
WO (1) WO2001035957A1 (enExample)
ZA (1) ZA200203315B (enExample)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0957073A1 (en) * 1998-05-12 1999-11-17 Schwarz Pharma Ag Novel derivatives of 3,3-diphenylpropylamines
DE19955190A1 (de) * 1999-11-16 2001-06-21 Sanol Arznei Schwarz Gmbh Stabile Salze neuartiger Derivate von 3,3-Diphenylpropylaminen
DE10028443C1 (de) * 2000-06-14 2002-05-29 Sanol Arznei Schwarz Gmbh Verfahren zur Herstellung von 3,3-Diarylpropylaminen, (R,S)- und (R)-4-Phenyl-2-chromanon-6-carbonsäure sowie (R)-4-Phenyl-2-chromanon-carbonsäure-cinchonidinsalz und deren Verwendung zur Herstellung eines rechtsdrehenden Hydroxybenzylalkohols und von pharmazeutischen Zusammensetzungen
DE10315878B4 (de) 2003-04-08 2009-06-04 Schwarz Pharma Ag Vorrichtung zur transdermalen Verabreichung von Fesoterodin und Verwendung
DE10315917A1 (de) * 2003-04-08 2004-11-18 Schwarz Pharma Ag Hochreine Basen von 3,3-Diphenylpropylaminmonoestern
WO2005012227A2 (en) * 2003-08-05 2005-02-10 Ranbaxy Laboratories Limited Process for preparation of 2-(3-diisopropylamino-1-phenylpropyl)-4-hydroxymethyl-phenol, a metabolite of tolterodine
ES2235648B1 (es) * 2003-12-22 2006-11-01 Ragactives, S.L. Procedimiento para la obtencion de tolterodina.
US8034823B2 (en) * 2005-02-22 2011-10-11 Savvipharm Inc Method of increasing drug oral bioavailability and compositions of less toxic orotate salts
KR100647068B1 (ko) 2005-09-15 2006-11-23 하나제약 주식회사 라세믹n,n-디이소프로필-3-(2-히드록시-5-메틸페닐)-3-페닐프로판아민의 제조방법
US8067594B2 (en) * 2006-05-24 2011-11-29 Pfizer Inc. Process for the production of benzopyran-2-ol derivatives
EP1862449A1 (en) * 2006-05-31 2007-12-05 Schwarz Pharma Ltd. A shortened synthesis of substituted hydroxymethyl phenols
US8344176B2 (en) * 2006-05-31 2013-01-01 Schwarz Pharma Ltd. Synthesis of substituted hydroxymethyl phenols
IES20060424A2 (en) * 2006-06-08 2007-10-31 Schwarz Pharma Ltd Accelerated synthesis of (3-Diisopropylamino-1-phenylpropyl)-4-(hydroxymethyl)phenol and its phenolic monoesters
ATE477234T1 (de) * 2006-06-09 2010-08-15 Schwarz Pharma Ltd Synthese von phenolischen estern von hydroxymethylphenolen
UY30394A1 (es) 2006-06-09 2007-11-30 Sanol Arznei Schwarz Gmbh Composiciones farmacéuticas estabilizadas que comprenden fesoterodina
US7807715B2 (en) 2006-06-09 2010-10-05 Ucb Pharma Gmbh Pharmaceutical compositions comprising fesoterodine
ES2464868T3 (es) 2006-06-12 2014-06-04 Ucb Pharma Gmbh Nuevo producto intermedio quiral, procedimiento para su preparación y su uso en la fabricación de tolterodina, fesoterodina o de su metabolito activo
IES20060435A2 (en) * 2006-06-12 2007-12-12 Schwarz Pharma Ltd Shortened synthesis using paraformaldehyde or trioxane
US20100217034A1 (en) * 2007-09-21 2010-08-26 Actavis Group Ptc Ehf Process for the Preparation of Fesoterodine
US20100297241A1 (en) * 2007-10-01 2010-11-25 Actavis Group Ptc Ehf Amorphous Fesoterodine Fumarate
WO2009122303A2 (en) * 2008-04-04 2009-10-08 Actavis Group Ptc Ehf Novel mandelate salt of fesoterodine
EP2323967A2 (en) * 2008-07-21 2011-05-25 Actavis Group PTC EHF Fesoterodine comprising a reduced amount of dehydroxyfesoterodine
IT1392082B1 (it) * 2008-12-10 2012-02-09 Chemi Spa Nuove forme solide della fesoterodina fumarato
EP2416761B1 (de) 2009-05-11 2015-02-11 ratiopharm GmbH Desfesoterodin in form eines weinsäuresalzes
IT1394217B1 (it) * 2009-05-15 2012-06-01 Chemi Spa Metodo di preparazione di fesoterodina e/o fesoterodina fumarato.
IT1394219B1 (it) 2009-05-15 2012-06-01 Chemi Spa Metodo di preparazione di fesoterodina fumarato di elevata purezza.
EP2459520A1 (en) 2009-09-03 2012-06-06 Teva Gyógyszergyár Zártköruen Muködo Részvénytársaság Crystalline forms of fesoterodine fumarate and fesoterodine base
IT1396373B1 (it) * 2009-10-29 2012-11-19 Dipharma Francis Srl Procedimento per la preparazione di fesoterodina.
EP2316432A1 (de) 2009-10-30 2011-05-04 ratiopharm GmbH Zusammensetzung enthaltend Fesoterodin und Ballaststoffe
US20110124903A1 (en) * 2009-11-20 2011-05-26 Actavis Group Ptc Ehf Solid state forms of fesoterodine intermediates
IT1397521B1 (it) * 2009-12-21 2013-01-16 Dipharma Francis Srl Procedimento per la preparazione di fesoterodina con un basso contenuto di impurezze.
IT1397920B1 (it) * 2010-02-08 2013-02-04 Dipharma Francis Srl Forma cristallina di fesoterodina fumarato e procedimento per la sua preparazione
EP2549985A1 (en) 2010-03-22 2013-01-30 Cadila Healthcare Limited Stable pharmaceutical compositions comprising fesoterodine
CA2796877A1 (en) 2010-04-30 2011-11-03 Merck Sharp & Dohme Corp. Novel beta 3 adrenergic receptor agonists
US20110282094A1 (en) * 2010-05-11 2011-11-17 Intas Pharmaceuticals Limited Process for preparation of phenolic monoesters of hydroxymethyl phenols
WO2011145019A1 (en) * 2010-05-17 2011-11-24 Orchid Chemicals And Pharmaceuticals Limited Improved process for diphenylpropylamine derivatives
IT1401451B1 (it) 2010-06-10 2013-07-26 Chemi Spa Nuovo processo di preparazione di 2-idrossi-4-fenil-3,4-diidro-2h-cromen-6-il-metanolo e (r)-2-[3-(diisopropilammino)-1-fenilpropil]-4-(idrossimetil)fenolo.
WO2011158257A1 (en) 2010-06-18 2011-12-22 Panacea Biotec Ltd Preparation process of fesoterodine and intermediates
WO2012025941A2 (en) 2010-08-25 2012-03-01 Cadila Healthcare Limited Processes for the preparation of fesoterodine
IT1403094B1 (it) * 2010-12-09 2013-10-04 Dipharma Francis Srl Procedimento per la preparazione di fesoterodina o un suo sale
WO2012098560A2 (en) * 2011-01-17 2012-07-26 Msn Laboratories Limited Process for the preparation of muscarinic receptor antagonist
TWI520732B (zh) 2011-01-18 2016-02-11 輝瑞有限公司 固體分子分散液
EP2508175A1 (en) 2011-04-08 2012-10-10 LEK Pharmaceuticals d.d. Pharmaceutical composition comprising fesoterodine or a salt or a solvate thereof
EP2508173A1 (en) 2011-04-08 2012-10-10 LEK Pharmaceuticals d.d. Stabilized pharmaceutical composition comprising fesoterodine
JP6234999B2 (ja) 2012-05-04 2017-11-22 クリスタル ファルマ、エセ、ア、ウCrystal Pharma,S.A.U. 光学的に活性な3,3−ジフェニルプロピルアミンを調製するための方法
ITMI20121232A1 (it) 2012-07-16 2014-01-17 Cambrex Profarmaco Milano Srl Procedimento per la preparazione di 2-(3-n,n-diisopropilamino-1-fenilpropil)-4-idrossimetil-fenolo e suoi derivati
TR201721437A2 (tr) 2017-12-25 2019-07-22 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Fesoterodi̇ni̇n modi̇fi̇ye salim sağlayan formülasyonlari
WO2022090235A1 (en) * 2020-10-27 2022-05-05 Wella Germany Gmbh 2-methoxymethyl-p-phenylenediamine in cosmetic grade quality

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU540707B2 (en) * 1980-11-14 1984-11-29 Eli Lilly And Company N-methyl-3-(2methyl phenoxy)-o-phenylpropyl amine
IL66831A0 (en) * 1981-10-05 1982-12-31 Kefalas As Indane derivatives
SE8800207D0 (sv) * 1988-01-22 1988-01-22 Kabivitrum Ab Nya aminer, deras anvendning och framstellning
DE69120699T2 (de) * 1990-03-08 1997-01-09 Fujisawa Pharmaceutical Co N-Monosubstituierte Cyclopentenylamine, ein Verfahren zu ihrer Herstellung, und ihre Verwendung als Medikament
JPH0483431A (ja) * 1990-07-26 1992-03-17 Seiko Epson Corp 選択呼出受信機
SE9203318D0 (sv) * 1992-11-06 1992-11-06 Kabi Pharmacia Ab Novel 3,3-diphenylpropylamines, their use and preparation
SE9701144D0 (sv) * 1997-03-27 1997-03-27 Pharmacia & Upjohn Ab Novel compounds, their use and preparation
EP0957073A1 (en) * 1998-05-12 1999-11-17 Schwarz Pharma Ag Novel derivatives of 3,3-diphenylpropylamines
DE19955190A1 (de) * 1999-11-16 2001-06-21 Sanol Arznei Schwarz Gmbh Stabile Salze neuartiger Derivate von 3,3-Diphenylpropylaminen

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