JP2010180243A5 - - Google Patents

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Publication number
JP2010180243A5
JP2010180243A5 JP2010098845A JP2010098845A JP2010180243A5 JP 2010180243 A5 JP2010180243 A5 JP 2010180243A5 JP 2010098845 A JP2010098845 A JP 2010098845A JP 2010098845 A JP2010098845 A JP 2010098845A JP 2010180243 A5 JP2010180243 A5 JP 2010180243A5
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JP
Japan
Prior art keywords
compound
acid
formula
chemical formula
residue
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP2010098845A
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English (en)
Japanese (ja)
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JP2010180243A (ja
JP5503393B2 (ja
Filing date
Publication date
Priority claimed from DE19955190A external-priority patent/DE19955190A1/de
Application filed filed Critical
Publication of JP2010180243A publication Critical patent/JP2010180243A/ja
Publication of JP2010180243A5 publication Critical patent/JP2010180243A5/ja
Application granted granted Critical
Publication of JP5503393B2 publication Critical patent/JP5503393B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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JP2010098845A 1999-11-16 2010-04-22 ３，３−ジフェニルプロピルアミン類の新規誘導体の安定な塩 Expired - Lifetime JP5503393B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19955190A DE19955190A1 (de) 1999-11-16 1999-11-16 Stabile Salze neuartiger Derivate von 3,3-Diphenylpropylaminen
DE19955190.1 1999-11-16

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2007042774A Division JP2007137895A (ja) 1999-11-16 2007-02-22 ３，３−ジフェニルプロピルアミン類の新規誘導体の安定な塩

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2013229622A Division JP5717824B2 (ja) 1999-11-16 2013-11-05 ３，３−ジフェニルプロピルアミン類の新規誘導体の安定な塩

Publications (3)

Publication Number Publication Date
JP2010180243A JP2010180243A (ja) 2010-08-19
JP2010180243A5 true JP2010180243A5 (enExample) 2011-09-08
JP5503393B2 JP5503393B2 (ja) 2014-05-28

Family

ID=7929277

Family Applications (6)

Application Number Title Priority Date Filing Date
JP2001537950A Expired - Lifetime JP4083431B2 (ja) 1999-11-16 2000-11-15 ３，３−ジフェニルプロピルアミン類の新規誘導体の安定な塩
JP2007042774A Pending JP2007137895A (ja) 1999-11-16 2007-02-22 ３，３−ジフェニルプロピルアミン類の新規誘導体の安定な塩
JP2010098844A Expired - Lifetime JP5650924B2 (ja) 1999-11-16 2010-04-22 ３，３−ジフェニルプロピルアミン類の新規誘導体の安定な塩
JP2010098845A Expired - Lifetime JP5503393B2 (ja) 1999-11-16 2010-04-22 ３，３−ジフェニルプロピルアミン類の新規誘導体の安定な塩
JP2011096911A Expired - Lifetime JP5290351B2 (ja) 1999-11-16 2011-04-25 ３，３−ジフェニルプロピルアミン類の新規誘導体の安定な塩
JP2013229622A Expired - Lifetime JP5717824B2 (ja) 1999-11-16 2013-11-05 ３，３−ジフェニルプロピルアミン類の新規誘導体の安定な塩

Family Applications Before (3)

Application Number Title Priority Date Filing Date
JP2001537950A Expired - Lifetime JP4083431B2 (ja) 1999-11-16 2000-11-15 ３，３−ジフェニルプロピルアミン類の新規誘導体の安定な塩
JP2007042774A Pending JP2007137895A (ja) 1999-11-16 2007-02-22 ３，３−ジフェニルプロピルアミン類の新規誘導体の安定な塩
JP2010098844A Expired - Lifetime JP5650924B2 (ja) 1999-11-16 2010-04-22 ３，３−ジフェニルプロピルアミン類の新規誘導体の安定な塩

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2011096911A Expired - Lifetime JP5290351B2 (ja) 1999-11-16 2011-04-25 ３，３−ジフェニルプロピルアミン類の新規誘導体の安定な塩
JP2013229622A Expired - Lifetime JP5717824B2 (ja) 1999-11-16 2013-11-05 ３，３−ジフェニルプロピルアミン類の新規誘導体の安定な塩

Country Status (30)

Country Link
US (1) US6858650B1 (enExample)
EP (3) EP1230209B3 (enExample)
JP (6) JP4083431B2 (enExample)
KR (2) KR100536095B1 (enExample)
CN (1) CN1215045C (enExample)
AT (3) ATE286872T1 (enExample)
AU (1) AU778132B2 (enExample)
BR (1) BRPI0015610C1 (enExample)
CA (1) CA2389749C (enExample)
CY (2) CY1106204T1 (enExample)
CZ (2) CZ302967B6 (enExample)
DE (5) DE29923134U1 (enExample)
DK (3) DK1690536T3 (enExample)
EA (1) EA005588B1 (enExample)
ES (3) ES2303708T3 (enExample)
GE (1) GEP20084430B (enExample)
HK (1) HK1045148B (enExample)
HU (2) HU228197B1 (enExample)
IL (2) IL149567A0 (enExample)
IS (2) IS2124B (enExample)
MX (1) MXPA02004603A (enExample)
NO (2) NO323920B1 (enExample)
NZ (1) NZ519230A (enExample)
PL (1) PL201422B1 (enExample)
PT (3) PT1481964E (enExample)
SI (3) SI1690536T1 (enExample)
SK (3) SK287430B6 (enExample)
UA (2) UA73324C2 (enExample)
WO (1) WO2001035957A1 (enExample)
ZA (1) ZA200203315B (enExample)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0957073A1 (en) * 1998-05-12 1999-11-17 Schwarz Pharma Ag Novel derivatives of 3,3-diphenylpropylamines
DE29923134U1 (de) * 1999-11-16 2000-06-29 Schwarz Pharma Ag, 40789 Monheim Stabile Salze neuartiger Derviate von 3,3-Diphenylpropylaminen
DE10028443C1 (de) * 2000-06-14 2002-05-29 Sanol Arznei Schwarz Gmbh Verfahren zur Herstellung von 3,3-Diarylpropylaminen, (R,S)- und (R)-4-Phenyl-2-chromanon-6-carbonsäure sowie (R)-4-Phenyl-2-chromanon-carbonsäure-cinchonidinsalz und deren Verwendung zur Herstellung eines rechtsdrehenden Hydroxybenzylalkohols und von pharmazeutischen Zusammensetzungen
DE10315917A1 (de) 2003-04-08 2004-11-18 Schwarz Pharma Ag Hochreine Basen von 3,3-Diphenylpropylaminmonoestern
DE10315878B4 (de) * 2003-04-08 2009-06-04 Schwarz Pharma Ag Vorrichtung zur transdermalen Verabreichung von Fesoterodin und Verwendung
WO2005012227A2 (en) * 2003-08-05 2005-02-10 Ranbaxy Laboratories Limited Process for preparation of 2-(3-diisopropylamino-1-phenylpropyl)-4-hydroxymethyl-phenol, a metabolite of tolterodine
ES2235648B1 (es) * 2003-12-22 2006-11-01 Ragactives, S.L. Procedimiento para la obtencion de tolterodina.
US8034823B2 (en) * 2005-02-22 2011-10-11 Savvipharm Inc Method of increasing drug oral bioavailability and compositions of less toxic orotate salts
KR100647068B1 (ko) 2005-09-15 2006-11-23 하나제약 주식회사 라세믹ｎ,ｎ-디이소프로필-3-(2-히드록시-5-메틸페닐)-3-페닐프로판아민의 제조방법
ATE480531T1 (de) * 2006-05-24 2010-09-15 Pfizer Ltd Verfahren zur herstellung von benzopyran-2- olderivaten
EP1862449A1 (en) * 2006-05-31 2007-12-05 Schwarz Pharma Ltd. A shortened synthesis of substituted hydroxymethyl phenols
JP5257353B2 (ja) * 2006-05-31 2013-08-07 シュウォーツ ファーマ リミテッド 置換ヒドロキシメチルフェノールの新規な合成
IES20060424A2 (en) * 2006-06-08 2007-10-31 Schwarz Pharma Ltd Accelerated synthesis of (3-Diisopropylamino-1-phenylpropyl)-4-(hydroxymethyl)phenol and its phenolic monoesters
DE602007008389D1 (de) 2006-06-09 2010-09-23 Schwarz Pharma Ltd Synthese von phenolischen estern von hydroxymethylphenolen
US7807715B2 (en) 2006-06-09 2010-10-05 Ucb Pharma Gmbh Pharmaceutical compositions comprising fesoterodine
CN101466371B (zh) * 2006-06-09 2011-10-05 施瓦茨制药有限公司 含非索罗定的稳定的药用组合物
IES20060435A2 (en) 2006-06-12 2007-12-12 Schwarz Pharma Ltd Shortened synthesis using paraformaldehyde or trioxane
EA018376B1 (ru) 2006-06-12 2013-07-30 Шварц Фарма Аг Новые хиральные промежуточные продукты, способ их получения и их применение в производстве толтеродина, фезотеродина или их активных метаболитов
US20100217034A1 (en) * 2007-09-21 2010-08-26 Actavis Group Ptc Ehf Process for the Preparation of Fesoterodine
US20100297241A1 (en) * 2007-10-01 2010-11-25 Actavis Group Ptc Ehf Amorphous Fesoterodine Fumarate
EP2294047A2 (en) * 2008-04-04 2011-03-16 Actavis Group PTC EHF Novel mandelate salt of fesoterodine
WO2010010464A2 (en) * 2008-07-21 2010-01-28 Actavis Group Ptc Ehf Fesoterodine substantially free of dehydroxy impurity
IT1392082B1 (it) * 2008-12-10 2012-02-09 Chemi Spa Nuove forme solide della fesoterodina fumarato
PL2416761T3 (pl) 2009-05-11 2015-07-31 Ratiopharm Gmbh Desfezoterodyna w postaci soli kwasu winowego
IT1394217B1 (it) * 2009-05-15 2012-06-01 Chemi Spa Metodo di preparazione di fesoterodina e/o fesoterodina fumarato.
IT1394219B1 (it) 2009-05-15 2012-06-01 Chemi Spa Metodo di preparazione di fesoterodina fumarato di elevata purezza.
WO2011029005A1 (en) 2009-09-03 2011-03-10 Teva Gyogyszergyar Zartkoruen Mukodo Reszvenytarsasag Crystalline forms of fesoterodine fumarate and fesoterodine base
IT1396373B1 (it) * 2009-10-29 2012-11-19 Dipharma Francis Srl Procedimento per la preparazione di fesoterodina.
EP2316432A1 (de) 2009-10-30 2011-05-04 ratiopharm GmbH Zusammensetzung enthaltend Fesoterodin und Ballaststoffe
US20110124903A1 (en) * 2009-11-20 2011-05-26 Actavis Group Ptc Ehf Solid state forms of fesoterodine intermediates
IT1397521B1 (it) * 2009-12-21 2013-01-16 Dipharma Francis Srl Procedimento per la preparazione di fesoterodina con un basso contenuto di impurezze.
IT1397920B1 (it) * 2010-02-08 2013-02-04 Dipharma Francis Srl Forma cristallina di fesoterodina fumarato e procedimento per la sua preparazione
US20130172411A1 (en) 2010-03-22 2013-07-04 Cadila Healthcare Limited Stable pharmaceutical compositions comprising fesoterodine
WO2011137054A1 (en) 2010-04-30 2011-11-03 Merck Sharp & Dohme Corp. Novel beta 3 adrenergic receptor agonists
US20110282094A1 (en) * 2010-05-11 2011-11-17 Intas Pharmaceuticals Limited Process for preparation of phenolic monoesters of hydroxymethyl phenols
WO2011145019A1 (en) * 2010-05-17 2011-11-24 Orchid Chemicals And Pharmaceuticals Limited Improved process for diphenylpropylamine derivatives
IT1401451B1 (it) 2010-06-10 2013-07-26 Chemi Spa Nuovo processo di preparazione di 2-idrossi-4-fenil-3,4-diidro-2h-cromen-6-il-metanolo e (r)-2-[3-(diisopropilammino)-1-fenilpropil]-4-(idrossimetil)fenolo.
WO2011158257A1 (en) 2010-06-18 2011-12-22 Panacea Biotec Ltd Preparation process of fesoterodine and intermediates
US9012678B2 (en) * 2010-08-25 2015-04-21 Cadila Healthcare Limited Processes for the preparation of fesoterodine
IT1403094B1 (it) * 2010-12-09 2013-10-04 Dipharma Francis Srl Procedimento per la preparazione di fesoterodina o un suo sale
WO2012098560A2 (en) * 2011-01-17 2012-07-26 Msn Laboratories Limited Process for the preparation of muscarinic receptor antagonist
TWI520732B (zh) 2011-01-18 2016-02-11 輝瑞有限公司 固體分子分散液
EP2508173A1 (en) 2011-04-08 2012-10-10 LEK Pharmaceuticals d.d. Stabilized pharmaceutical composition comprising fesoterodine
EP2508175A1 (en) 2011-04-08 2012-10-10 LEK Pharmaceuticals d.d. Pharmaceutical composition comprising fesoterodine or a salt or a solvate thereof
CA2873721C (en) 2012-05-04 2021-06-22 Crystal Pharma, S.A.U. Process for the preparation of optically active 3,3-diphenylpropylamines
ITMI20121232A1 (it) 2012-07-16 2014-01-17 Cambrex Profarmaco Milano Srl Procedimento per la preparazione di 2-(3-n,n-diisopropilamino-1-fenilpropil)-4-idrossimetil-fenolo e suoi derivati
TR201721437A2 (tr) 2017-12-25 2019-07-22 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Fesoterodi̇ni̇n modi̇fi̇ye salim sağlayan formülasyonlari
WO2022090235A1 (en) * 2020-10-27 2022-05-05 Wella Germany Gmbh 2-methoxymethyl-p-phenylenediamine in cosmetic grade quality

Family Cites Families (9)

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Publication number Priority date Publication date Assignee Title
PL233786A1 (enExample) * 1980-11-14 1982-05-24 Lilly Co Eli
IL66831A0 (en) * 1981-10-05 1982-12-31 Kefalas As Indane derivatives
SE8800207D0 (sv) * 1988-01-22 1988-01-22 Kabivitrum Ab Nya aminer, deras anvendning och framstellning
ATE140213T1 (de) * 1990-03-08 1996-07-15 Fujisawa Pharmaceutical Co N-monosubstituierte cyclopentenylamine, ein verfahren zu ihrer herstellung, und ihre verwendung als medikament
JPH0483431A (ja) * 1990-07-26 1992-03-17 Seiko Epson Corp 選択呼出受信機
SE9203318D0 (sv) * 1992-11-06 1992-11-06 Kabi Pharmacia Ab Novel 3,3-diphenylpropylamines, their use and preparation
SE9701144D0 (sv) * 1997-03-27 1997-03-27 Pharmacia & Upjohn Ab Novel compounds, their use and preparation
EP0957073A1 (en) * 1998-05-12 1999-11-17 Schwarz Pharma Ag Novel derivatives of 3,3-diphenylpropylamines
DE29923134U1 (de) * 1999-11-16 2000-06-29 Schwarz Pharma Ag, 40789 Monheim Stabile Salze neuartiger Derviate von 3,3-Diphenylpropylaminen

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