JP2009543799A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2009543799A5 JP2009543799A5 JP2009519632A JP2009519632A JP2009543799A5 JP 2009543799 A5 JP2009543799 A5 JP 2009543799A5 JP 2009519632 A JP2009519632 A JP 2009519632A JP 2009519632 A JP2009519632 A JP 2009519632A JP 2009543799 A5 JP2009543799 A5 JP 2009543799A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- amount
- methoxy
- furfuryl
- disubstituted purine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 25
- -1 6,9-disubstituted purine Chemical class 0.000 claims 24
- 210000004962 mammalian cell Anatomy 0.000 claims 10
- 229940083251 peripheral vasodilators purine derivative Drugs 0.000 claims 8
- 230000002411 adverse Effects 0.000 claims 6
- 230000032683 aging Effects 0.000 claims 6
- 230000000694 effects Effects 0.000 claims 6
- 150000003839 salts Chemical class 0.000 claims 5
- 210000003491 skin Anatomy 0.000 claims 4
- 210000004927 skin cell Anatomy 0.000 claims 4
- 241000124008 Mammalia Species 0.000 claims 3
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 3
- 230000004968 inflammatory condition Effects 0.000 claims 1
- 208000017520 skin disease Diseases 0.000 claims 1
- 0 C*c1c2nc[n](*)c2ncn1 Chemical compound C*c1c2nc[n](*)c2ncn1 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US80687106P | 2006-07-10 | 2006-07-10 | |
| US60/806,871 | 2006-07-10 | ||
| US11/774,652 | 2007-07-09 | ||
| US11/774,652 US20080009508A1 (en) | 2006-07-10 | 2007-07-09 | 6,9-Disubstituted Purine Derivatives And Their Use For Treating Skin |
| PCT/US2007/073142 WO2008008770A2 (en) | 2006-07-10 | 2007-07-10 | 6, 9-disubstituted purine derivatives and their use for treating skin |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009543799A JP2009543799A (ja) | 2009-12-10 |
| JP2009543799A5 true JP2009543799A5 (enExample) | 2010-09-09 |
| JP5309023B2 JP5309023B2 (ja) | 2013-10-09 |
Family
ID=38919793
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009519632A Expired - Fee Related JP5309023B2 (ja) | 2006-07-10 | 2007-07-10 | ６，９−二置換プリン誘導体および皮膚を処置するためのその使用 |
Country Status (16)
| Country | Link |
|---|---|
| US (4) | US20080009508A1 (enExample) |
| EP (1) | EP2043630B1 (enExample) |
| JP (1) | JP5309023B2 (enExample) |
| KR (1) | KR101478727B1 (enExample) |
| CN (1) | CN101646435B (enExample) |
| AU (1) | AU2007272576B2 (enExample) |
| BR (1) | BRPI0714161A2 (enExample) |
| CA (1) | CA2657516C (enExample) |
| EA (1) | EA015848B1 (enExample) |
| ES (1) | ES2603216T3 (enExample) |
| IL (1) | IL196442A (enExample) |
| MX (1) | MX2009000347A (enExample) |
| MY (1) | MY158100A (enExample) |
| NO (1) | NO20090598L (enExample) |
| NZ (1) | NZ574711A (enExample) |
| WO (1) | WO2008008770A2 (enExample) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7960397B2 (en) * | 2007-12-28 | 2011-06-14 | Institute Of Experimental Botany, Academy Of Sciences Of The Czech Republic | 6,9-disubstituted purine derivatives and their use as cosmetics and cosmetic compositions |
| PE20120493A1 (es) | 2009-06-29 | 2012-05-20 | Incyte Corp | Pirimidinonas como inhibidores de pi3k |
| TW201130842A (en) * | 2009-12-18 | 2011-09-16 | Incyte Corp | Substituted fused aryl and heteroaryl derivatives as PI3K inhibitors |
| US8759359B2 (en) | 2009-12-18 | 2014-06-24 | Incyte Corporation | Substituted heteroaryl fused derivatives as PI3K inhibitors |
| AR081823A1 (es) | 2010-04-14 | 2012-10-24 | Incyte Corp | DERIVADOS FUSIONADOS COMO INHIBIDORES DE PI3Kd |
| EP2395086A1 (en) * | 2010-06-09 | 2011-12-14 | Chanel Parfums Beauté | Inhibitors of micro-RNAs for use for preventing and/or attenuating skin ageing and/or for hydrating skin |
| ES2459143T3 (es) * | 2010-06-09 | 2014-05-08 | Chanel Parfums Beauté | Inhibidores de varios microARN para usar en la prevención y/o atenuación del envejecimiento cutáneo y/o para hidratar la piel |
| WO2011163195A1 (en) | 2010-06-21 | 2011-12-29 | Incyte Corporation | Fused pyrrole derivatives as pi3k inhibitors |
| ES2764848T3 (es) | 2010-12-20 | 2020-06-04 | Incyte Holdings Corp | N-(1-(fenilo sustituido)etilo)-9H-purina-6-aminas como inhibidores de PI3K |
| WO2012125629A1 (en) | 2011-03-14 | 2012-09-20 | Incyte Corporation | Substituted diamino-pyrimidine and diamino-pyridine derivatives as pi3k inhibitors |
| WO2012135009A1 (en) | 2011-03-25 | 2012-10-04 | Incyte Corporation | Pyrimidine-4,6-diamine derivatives as pi3k inhibitors |
| KR20230038593A (ko) | 2011-09-02 | 2023-03-20 | 인사이트 홀딩스 코포레이션 | Ｐｉ３ｋ 억제제로서 헤테로시클릴아민 |
| US20130072506A1 (en) | 2011-09-16 | 2013-03-21 | Lenka ZAHAJSKA | 6,8-disubstituted purine compositions |
| AR090548A1 (es) | 2012-04-02 | 2014-11-19 | Incyte Corp | Azaheterociclobencilaminas biciclicas como inhibidores de pi3k |
| WO2015191677A1 (en) | 2014-06-11 | 2015-12-17 | Incyte Corporation | Bicyclic heteroarylaminoalkyl phenyl derivatives as pi3k inhibitors |
| CZ306984B6 (cs) | 2014-12-15 | 2017-11-01 | Ústav experimentální botaniky AV ČR, v. v. i. | 6,8-Disubstituované-9-(heterocyklyl)puriny, přípravky obsahující tyto deriváty a jejich použití v kosmetických a medicínských aplikacích |
| PH12017501538B1 (en) | 2015-02-27 | 2024-02-14 | Incyte Holdings Corp | Salts of p13k inhibitor and processes for their preparation |
| US9988401B2 (en) | 2015-05-11 | 2018-06-05 | Incyte Corporation | Crystalline forms of a PI3K inhibitor |
| US9732097B2 (en) | 2015-05-11 | 2017-08-15 | Incyte Corporation | Process for the synthesis of a phosphoinositide 3-kinase inhibitor |
| CZ307722B6 (cs) * | 2015-08-28 | 2019-03-27 | Univerzita PalackĂ©ho v Olomouci | Adeninové deriváty a jejich použití |
| CZ307868B6 (cs) | 2017-04-28 | 2019-07-10 | Univerzita PalackĂ©ho v Olomouci | Deriváty 9-(2-oxacykloalkyl)-9H-purin-2,6-diaminu, přípravky obsahující tyto deriváty a jejich použití |
| CN112469418A (zh) | 2018-06-01 | 2021-03-09 | 因赛特公司 | 治疗pi3k相关病症的给药方案 |
| WO2022012702A1 (en) | 2020-07-13 | 2022-01-20 | Univerzita Palackeho V Olomouci | Nitrogen heterocyclic cytokinin derivatives, compositions containing these derivatives and use thereof |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5371089A (en) * | 1987-02-26 | 1994-12-06 | Senetek, Plc | Method and composition for ameliorating the adverse effects of aging |
| US5021422A (en) * | 1989-06-08 | 1991-06-04 | Senetek Plc | Method and composition for treating hyperproliferative skin diseases using 6-aminopurine cytokinins |
| WO2004037159A2 (en) * | 2002-10-23 | 2004-05-06 | Obetherapy Biotechnology | Compounds, compositions and methods for modulating fat metabolism |
| EP2145888A1 (en) * | 2003-09-18 | 2010-01-20 | Conforma Therapeutics Corporation | Deazapurine derivatives as HSP90-Inhibitors |
| JP2009500394A (ja) * | 2005-07-08 | 2009-01-08 | ザ プロクター アンド ギャンブル カンパニー | パーソナルケア組成物及び哺乳類の皮膚と毛髪を美化する方法 |
-
2007
- 2007-07-09 US US11/774,652 patent/US20080009508A1/en not_active Abandoned
- 2007-07-10 EA EA200970110A patent/EA015848B1/ru not_active IP Right Cessation
- 2007-07-10 MX MX2009000347A patent/MX2009000347A/es not_active Application Discontinuation
- 2007-07-10 BR BRPI0714161-0A patent/BRPI0714161A2/pt not_active IP Right Cessation
- 2007-07-10 MY MYPI20090112A patent/MY158100A/en unknown
- 2007-07-10 CN CN200780031839XA patent/CN101646435B/zh not_active Expired - Fee Related
- 2007-07-10 EP EP07799439.0A patent/EP2043630B1/en not_active Not-in-force
- 2007-07-10 ES ES07799439.0T patent/ES2603216T3/es active Active
- 2007-07-10 KR KR1020097002557A patent/KR101478727B1/ko not_active Expired - Fee Related
- 2007-07-10 WO PCT/US2007/073142 patent/WO2008008770A2/en not_active Ceased
- 2007-07-10 JP JP2009519632A patent/JP5309023B2/ja not_active Expired - Fee Related
- 2007-07-10 AU AU2007272576A patent/AU2007272576B2/en not_active Ceased
- 2007-07-10 NZ NZ574711A patent/NZ574711A/en not_active IP Right Cessation
- 2007-07-10 CA CA2657516A patent/CA2657516C/en not_active Expired - Fee Related
-
2009
- 2009-01-11 IL IL196442A patent/IL196442A/en active IP Right Grant
- 2009-02-06 NO NO20090598A patent/NO20090598L/no not_active Application Discontinuation
-
2010
- 2010-05-24 US US12/786,027 patent/US20100234401A1/en not_active Abandoned
-
2011
- 2011-05-26 US US13/116,636 patent/US20110224238A1/en not_active Abandoned
-
2012
- 2012-09-28 US US13/630,673 patent/US20130072505A1/en not_active Abandoned