JP2009523005A5 - - Google Patents
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- Publication number
- JP2009523005A5 JP2009523005A5 JP2007511675A JP2007511675A JP2009523005A5 JP 2009523005 A5 JP2009523005 A5 JP 2009523005A5 JP 2007511675 A JP2007511675 A JP 2007511675A JP 2007511675 A JP2007511675 A JP 2007511675A JP 2009523005 A5 JP2009523005 A5 JP 2009523005A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- polynucleotide
- group
- snp
- nucleic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 claims 12
- 108091033319 polynucleotide Proteins 0.000 claims 11
- 102000040430 polynucleotide Human genes 0.000 claims 11
- 239000002157 polynucleotide Substances 0.000 claims 11
- 239000002773 nucleotide Substances 0.000 claims 10
- 125000003729 nucleotide group Chemical group 0.000 claims 10
- 102000039446 nucleic acids Human genes 0.000 claims 7
- 108020004707 nucleic acids Proteins 0.000 claims 7
- 150000007523 nucleic acids Chemical class 0.000 claims 7
- 108700028369 Alleles Proteins 0.000 claims 5
- 206010016654 Fibrosis Diseases 0.000 claims 5
- 208000019425 cirrhosis of liver Diseases 0.000 claims 5
- 229920001184 polypeptide Polymers 0.000 claims 4
- 102000004196 processed proteins & peptides Human genes 0.000 claims 4
- 108090000765 processed proteins & peptides Proteins 0.000 claims 4
- 239000003795 chemical substances by application Substances 0.000 claims 3
- 230000004761 fibrosis Effects 0.000 claims 3
- 125000003275 alpha amino acid group Chemical group 0.000 claims 2
- 238000003556 assay Methods 0.000 claims 2
- 230000007882 cirrhosis Effects 0.000 claims 2
- 239000000523 sample Substances 0.000 claims 2
- 108090000790 Enzymes Proteins 0.000 claims 1
- 102000004190 Enzymes Human genes 0.000 claims 1
- 101710163270 Nuclease Proteins 0.000 claims 1
- 108091034117 Oligonucleotide Proteins 0.000 claims 1
- 230000003321 amplification Effects 0.000 claims 1
- 238000004458 analytical method Methods 0.000 claims 1
- 239000000427 antigen Substances 0.000 claims 1
- 108091007433 antigens Proteins 0.000 claims 1
- 102000036639 antigens Human genes 0.000 claims 1
- 230000015572 biosynthetic process Effects 0.000 claims 1
- 238000001514 detection method Methods 0.000 claims 1
- 230000029087 digestion Effects 0.000 claims 1
- 239000012634 fragment Substances 0.000 claims 1
- 238000009396 hybridization Methods 0.000 claims 1
- 238000002955 isolation Methods 0.000 claims 1
- 238000003199 nucleic acid amplification method Methods 0.000 claims 1
- 102000054765 polymorphisms of proteins Human genes 0.000 claims 1
- 238000012163 sequencing technique Methods 0.000 claims 1
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US56884604P | 2004-05-07 | 2004-05-07 | |
| US60/568,846 | 2004-05-07 | ||
| US58260904P | 2004-06-25 | 2004-06-25 | |
| US60/582,609 | 2004-06-25 | ||
| US59955404P | 2004-08-09 | 2004-08-09 | |
| US60/599,554 | 2004-08-09 | ||
| PCT/US2005/016051 WO2005111241A2 (en) | 2004-05-07 | 2005-05-09 | Genetic polymorphisms associated with liver fibrosis methods of detection and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011023321A Division JP2011142914A (ja) | 2004-05-07 | 2011-02-04 | 肝線維症に関連する遺伝的多型、その検出方法および使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009523005A JP2009523005A (ja) | 2009-06-18 |
| JP2009523005A5 true JP2009523005A5 (enExample) | 2009-07-30 |
| JP5236286B2 JP5236286B2 (ja) | 2013-07-17 |
Family
ID=35394750
Family Applications (8)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007511675A Expired - Lifetime JP5236286B2 (ja) | 2004-05-07 | 2005-05-09 | 肝線維症に関連する遺伝的多型、その検出方法および使用 |
| JP2011023321A Withdrawn JP2011142914A (ja) | 2004-05-07 | 2011-02-04 | 肝線維症に関連する遺伝的多型、その検出方法および使用 |
| JP2013143224A Withdrawn JP2013233150A (ja) | 2004-05-07 | 2013-07-09 | 肝線維症に関連する遺伝的多型、その検出方法および使用 |
| JP2013143223A Expired - Lifetime JP5733844B2 (ja) | 2004-05-07 | 2013-07-09 | 肝線維症に関連する遺伝的多型、その検出方法および使用 |
| JP2015182498A Expired - Lifetime JP6124968B2 (ja) | 2004-05-07 | 2015-09-16 | 肝線維症に関連する遺伝的多型、その検出方法および使用 |
| JP2015182499A Withdrawn JP2016027815A (ja) | 2004-05-07 | 2015-09-16 | 肝線維症に関連する遺伝的多型、その検出方法および使用 |
| JP2017176520A Withdrawn JP2018023392A (ja) | 2004-05-07 | 2017-09-14 | 肝線維症に関連する遺伝的多型、その検出方法および使用 |
| JP2017176519A Expired - Fee Related JP6448149B2 (ja) | 2004-05-07 | 2017-09-14 | 肝線維症に関連する遺伝的多型、その検出方法および使用 |
Family Applications After (7)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011023321A Withdrawn JP2011142914A (ja) | 2004-05-07 | 2011-02-04 | 肝線維症に関連する遺伝的多型、その検出方法および使用 |
| JP2013143224A Withdrawn JP2013233150A (ja) | 2004-05-07 | 2013-07-09 | 肝線維症に関連する遺伝的多型、その検出方法および使用 |
| JP2013143223A Expired - Lifetime JP5733844B2 (ja) | 2004-05-07 | 2013-07-09 | 肝線維症に関連する遺伝的多型、その検出方法および使用 |
| JP2015182498A Expired - Lifetime JP6124968B2 (ja) | 2004-05-07 | 2015-09-16 | 肝線維症に関連する遺伝的多型、その検出方法および使用 |
| JP2015182499A Withdrawn JP2016027815A (ja) | 2004-05-07 | 2015-09-16 | 肝線維症に関連する遺伝的多型、その検出方法および使用 |
| JP2017176520A Withdrawn JP2018023392A (ja) | 2004-05-07 | 2017-09-14 | 肝線維症に関連する遺伝的多型、その検出方法および使用 |
| JP2017176519A Expired - Fee Related JP6448149B2 (ja) | 2004-05-07 | 2017-09-14 | 肝線維症に関連する遺伝的多型、その検出方法および使用 |
Country Status (5)
| Country | Link |
|---|---|
| US (7) | US7820380B2 (enExample) |
| EP (5) | EP2412826B1 (enExample) |
| JP (8) | JP5236286B2 (enExample) |
| CA (2) | CA2566256C (enExample) |
| WO (1) | WO2005111241A2 (enExample) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7666584B2 (en) * | 2005-09-01 | 2010-02-23 | Philadelphia Health & Education Coporation | Identification of a pin specific gene and protein (PIN-1) useful as a diagnostic treatment for prostate cancer |
| US7727725B2 (en) | 2006-04-27 | 2010-06-01 | Celera Corporation | Genetic polymorphisms associated with liver fibrosis, methods of detection and uses thereof |
| EP2099467B1 (en) * | 2006-10-03 | 2017-05-10 | University Of Medicine And Dentistry Of New Jersey | Atap peptides, nucleic acids encoding the same and associated methods of use |
| WO2008132763A2 (en) * | 2007-04-30 | 2008-11-06 | Decode Genetics Ehf | Genetic variants useful for risk assessment of coronary artery disease and myocardial infarction |
| US8039212B2 (en) * | 2007-11-05 | 2011-10-18 | Celera Corporation | Genetic polymorphisms associated with liver fibrosis, methods of detection and uses thereof |
| WO2009147246A1 (en) * | 2008-06-06 | 2009-12-10 | Medizinische Universität Graz | Compounds reducing or inhibiting the expression of pkd1 for diagnosis and therapy of brain tumors |
| EP2389439A4 (en) * | 2009-01-23 | 2013-02-13 | Agency Science Tech & Res | EINBASEN POLYMORPHISM IN AN INTRONIC P53 BINDING MOTIF OF THE PRKAG2 GENE |
| US10307167B2 (en) | 2012-12-14 | 2019-06-04 | Corquest Medical, Inc. | Assembly and method for left atrial appendage occlusion |
| US10813630B2 (en) | 2011-08-09 | 2020-10-27 | Corquest Medical, Inc. | Closure system for atrial wall |
| US10314594B2 (en) | 2012-12-14 | 2019-06-11 | Corquest Medical, Inc. | Assembly and method for left atrial appendage occlusion |
| ME03009B (me) | 2011-09-16 | 2018-10-20 | Gilead Pharmasset Llc | Metode za lecenje hcv-a |
| US8889159B2 (en) | 2011-11-29 | 2014-11-18 | Gilead Pharmasset Llc | Compositions and methods for treating hepatitis C virus |
| ES2423154B1 (es) * | 2012-03-12 | 2014-07-15 | Universidad Autónoma de Madrid | Método in vitro de pronóstico de cirrosis hepática |
| ES2422874B1 (es) * | 2012-03-12 | 2014-07-15 | Universidad Autnoma De Madrid | Método in vitro de pronóstico de fibrosis hepática grave |
| CN103570553B (zh) | 2012-08-01 | 2016-08-10 | 中国科学院兰州化学物理研究所 | 一种通过催化烷基化制备n-取代胺类化合物的方法 |
| US20140142689A1 (en) | 2012-11-21 | 2014-05-22 | Didier De Canniere | Device and method of treating heart valve malfunction |
| UA118256C2 (uk) | 2013-01-31 | 2018-12-26 | Гіліад Фармассет Елелсі | Комбінований склад двох противірусних сполук |
| WO2015014763A2 (en) * | 2013-08-02 | 2015-02-05 | Echosens | Non-invasive system for calculating a human or animal, reliable, standardized and complete score |
| US9566443B2 (en) | 2013-11-26 | 2017-02-14 | Corquest Medical, Inc. | System for treating heart valve malfunction including mitral regurgitation |
| US10842626B2 (en) | 2014-12-09 | 2020-11-24 | Didier De Canniere | Intracardiac device to correct mitral regurgitation |
| CN110446785B (zh) * | 2017-01-23 | 2024-04-26 | 瑞泽恩制药公司 | Hsd17b13变体及其应用 |
| KR20190139869A (ko) | 2017-04-11 | 2019-12-18 | 리제너론 파마슈티칼스 인코포레이티드 | 하이드록시스테로이드 (17-베타) 탈수소효소(hsd17b) 패밀리의 구성원의 조절인자의 활성도를 스크리닝하기 위한 검정 |
| US10961583B2 (en) | 2017-10-11 | 2021-03-30 | Regeneron Phramaceuticals, Inc. | Inhibition of HSD17B13 in the treatment of liver disease in patients expressing the PNPLA3 I148M variation |
| CA3091146A1 (en) | 2018-03-21 | 2019-09-26 | Regeneron Pharmaceuticals, Inc. | 17.beta.-hydroxysteroid dehydrogenase type 13 (hsd17b13) irna compositions and methods of use thereof |
| US11216742B2 (en) | 2019-03-04 | 2022-01-04 | Iocurrents, Inc. | Data compression and communication using machine learning |
| WO2021051009A1 (en) * | 2019-09-11 | 2021-03-18 | City Of Hope | Methods and compositions to direct breakdown of insulin mrna in benign fashion |
| EP4055174A4 (en) * | 2019-11-08 | 2024-01-03 | The Board Of Regents Of The University Of Texas System | Transgene cassettes, aav vectors and aav viral vectors for the expression of human codon-optimized slc6a1 |
| WO2021222623A1 (en) * | 2020-04-29 | 2021-11-04 | Washington University | Compositions and methods for inhibiting viral recognition sites |
| KR102455051B1 (ko) * | 2020-05-08 | 2022-10-17 | 가톨릭대학교 산학협력단 | 혈청내 Daxx 단백질의 측정을 통한 만성 간질환의 진단 |
| GB202008269D0 (en) * | 2020-06-02 | 2020-07-15 | Oxford Biodynamics Ltd | Detecting a chromosome marker |
| US12097498B2 (en) | 2020-12-31 | 2024-09-24 | 3M Innovative Properties Company | Nanopatterned films with patterned surface chemistry |
| IL308883A (en) * | 2021-05-28 | 2024-01-01 | Arrowhead Pharmaceuticals Inc | RNAi AGENTS FOR INHIBITING EXPRESSION OF MUCIN 5AC (MUC5AC), COMPOSITIONS THEREOF, AND METHODS OF USE |
| IL311468A (en) * | 2021-09-22 | 2024-05-01 | Imagine Pharma Llc | Compositions and methods for the proliferation of insulin- and glucagon-secreting cells from type 1 diabetic pancreatic tissue and their therapeutic uses |
| CA3238030A1 (en) * | 2021-11-12 | 2023-05-19 | Research Institute At Nationwide Children's Hospital | Materials and methods for slc6a1 gene therapy |
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-
2005
- 2005-05-09 US US11/124,367 patent/US7820380B2/en not_active Expired - Fee Related
- 2005-05-09 EP EP11165258.2A patent/EP2412826B1/en not_active Expired - Lifetime
- 2005-05-09 WO PCT/US2005/016051 patent/WO2005111241A2/en not_active Ceased
- 2005-05-09 EP EP11165274.9A patent/EP2423327B1/en not_active Expired - Lifetime
- 2005-05-09 CA CA2566256A patent/CA2566256C/en not_active Expired - Lifetime
- 2005-05-09 EP EP05746576A patent/EP1745154B1/en not_active Expired - Lifetime
- 2005-05-09 EP EP11165250.9A patent/EP2423326B1/en not_active Expired - Lifetime
- 2005-05-09 JP JP2007511675A patent/JP5236286B2/ja not_active Expired - Lifetime
- 2005-05-09 CA CA2852855A patent/CA2852855C/en not_active Expired - Lifetime
- 2005-05-09 EP EP11165266.5A patent/EP2412827B1/en not_active Expired - Lifetime
-
2010
- 2010-09-20 US US12/886,016 patent/US8071302B2/en not_active Expired - Fee Related
-
2011
- 2011-02-04 JP JP2011023321A patent/JP2011142914A/ja not_active Withdrawn
- 2011-10-27 US US13/283,344 patent/US20120276528A1/en not_active Abandoned
-
2013
- 2013-02-11 US US13/764,086 patent/US20140072957A1/en not_active Abandoned
- 2013-07-09 JP JP2013143224A patent/JP2013233150A/ja not_active Withdrawn
- 2013-07-09 JP JP2013143223A patent/JP5733844B2/ja not_active Expired - Lifetime
-
2015
- 2015-07-13 US US14/797,998 patent/US20160032388A1/en not_active Abandoned
- 2015-09-16 JP JP2015182498A patent/JP6124968B2/ja not_active Expired - Lifetime
- 2015-09-16 JP JP2015182499A patent/JP2016027815A/ja not_active Withdrawn
-
2017
- 2017-09-14 JP JP2017176520A patent/JP2018023392A/ja not_active Withdrawn
- 2017-09-14 JP JP2017176519A patent/JP6448149B2/ja not_active Expired - Fee Related
-
2018
- 2018-04-27 US US15/964,883 patent/US10718023B2/en not_active Expired - Fee Related
-
2020
- 2020-06-08 US US16/895,440 patent/US20210025000A1/en not_active Abandoned
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