JP2009506075A5 - - Google Patents
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- Publication number
- JP2009506075A5 JP2009506075A5 JP2008528247A JP2008528247A JP2009506075A5 JP 2009506075 A5 JP2009506075 A5 JP 2009506075A5 JP 2008528247 A JP2008528247 A JP 2008528247A JP 2008528247 A JP2008528247 A JP 2008528247A JP 2009506075 A5 JP2009506075 A5 JP 2009506075A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- unsaturated
- aromatic
- saturated
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 CC(*)C(*)*NC(*)(*=C)O Chemical compound CC(*)C(*)*NC(*)(*=C)O 0.000 description 4
- DICNFKINDZVTAN-DDJNEFBRSA-N CC([C@@H]([C@@](C)(C1)OC)[O]=C)O[C@H]1O[C@@H]([C@H](C)[C@@H](C)[C@@](C)(C[C@@H](C)C([C@H](C)C([C@@](C)(CO1)O)[O]=C)=O)OC)C(C)C1=O Chemical compound CC([C@@H]([C@@](C)(C1)OC)[O]=C)O[C@H]1O[C@@H]([C@H](C)[C@@H](C)[C@@](C)(C[C@@H](C)C([C@H](C)C([C@@](C)(CO1)O)[O]=C)=O)OC)C(C)C1=O DICNFKINDZVTAN-DDJNEFBRSA-N 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US71144305P | 2005-08-24 | 2005-08-24 | |
| US60/711,443 | 2005-08-24 | ||
| US76290706P | 2006-01-26 | 2006-01-26 | |
| US60/762,907 | 2006-01-26 | ||
| PCT/US2006/033645 WO2007025284A1 (en) | 2005-08-24 | 2006-08-24 | Triazole compounds and methods of making and using the same |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013169594A Division JP5981401B2 (ja) | 2005-08-24 | 2013-08-19 | トリアゾール化合物ならびにこれを作製する方法および使用する方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009506075A JP2009506075A (ja) | 2009-02-12 |
| JP2009506075A5 true JP2009506075A5 (https=) | 2009-10-08 |
| JP5395432B2 JP5395432B2 (ja) | 2014-01-22 |
Family
ID=37467427
Family Applications (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008528247A Expired - Fee Related JP5395432B2 (ja) | 2005-08-24 | 2006-08-24 | トリアゾール化合物ならびにこれを作製する方法および使用する方法 |
| JP2008528168A Withdrawn JP2009506066A (ja) | 2005-08-24 | 2006-08-24 | トリアゾール化合物ならびにこれを作製する方法および使用する方法 |
| JP2013169594A Expired - Fee Related JP5981401B2 (ja) | 2005-08-24 | 2013-08-19 | トリアゾール化合物ならびにこれを作製する方法および使用する方法 |
| JP2015223733A Pending JP2016094421A (ja) | 2005-08-24 | 2015-11-16 | トリアゾール化合物ならびにこれを作製する方法および使用する方法 |
| JP2017141745A Pending JP2018008970A (ja) | 2005-08-24 | 2017-07-21 | トリアゾール化合物ならびにこれを作製する方法および使用する方法 |
| JP2018169395A Pending JP2019023194A (ja) | 2005-08-24 | 2018-09-11 | トリアゾール化合物ならびにこれを作製する方法および使用する方法 |
Family Applications After (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008528168A Withdrawn JP2009506066A (ja) | 2005-08-24 | 2006-08-24 | トリアゾール化合物ならびにこれを作製する方法および使用する方法 |
| JP2013169594A Expired - Fee Related JP5981401B2 (ja) | 2005-08-24 | 2013-08-19 | トリアゾール化合物ならびにこれを作製する方法および使用する方法 |
| JP2015223733A Pending JP2016094421A (ja) | 2005-08-24 | 2015-11-16 | トリアゾール化合物ならびにこれを作製する方法および使用する方法 |
| JP2017141745A Pending JP2018008970A (ja) | 2005-08-24 | 2017-07-21 | トリアゾール化合物ならびにこれを作製する方法および使用する方法 |
| JP2018169395A Pending JP2019023194A (ja) | 2005-08-24 | 2018-09-11 | トリアゾール化合物ならびにこれを作製する方法および使用する方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (5) | US8278281B2 (https=) |
| EP (3) | EP3290427A1 (https=) |
| JP (6) | JP5395432B2 (https=) |
| DK (1) | DK1934238T3 (https=) |
| ES (1) | ES2638427T3 (https=) |
| HR (1) | HRP20171285T1 (https=) |
| WO (2) | WO2007025284A1 (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1723159B1 (en) | 2004-02-27 | 2019-06-12 | Melinta Therapeutics, Inc. | Macrocyclic compounds and methods of making and using the same |
| EP1934237A2 (en) | 2005-08-24 | 2008-06-25 | Rib-X Pharmaceuticals, Inc. | Triazole compounds and methods of making and using the same |
| EP3290427A1 (en) * | 2005-08-24 | 2018-03-07 | Melinta Therapeutics, Inc. | Triazole compounds and methods of making and using the same |
| WO2008106204A1 (en) * | 2007-02-28 | 2008-09-04 | Rib-X-Pharmaceuticals, Inc. | Macrolide compounds and methods of making and using the same |
| BRPI0823405A2 (pt) * | 2007-07-06 | 2012-12-25 | Paratek Pharmaceuticals, Inc. | mÉtodos para sintetizar compostos de tetraciclina substituÍda |
| JP2011026260A (ja) * | 2009-07-28 | 2011-02-10 | Central Glass Co Ltd | ３位に脱離基を有する２−フルオロプロピルアミン保護体または該アミンｎ−アルキル保護体 |
| CN101619085B (zh) * | 2009-08-11 | 2015-04-22 | 沈阳药科大学 | 红霉素衍生物及其作为肿瘤细胞增殖抑制剂的用途 |
| AR092278A1 (es) * | 2012-08-31 | 2015-04-08 | Novartis Ag | Proceso de obtencion de derivados n-acilicos de bifenil-alanina e intermediarios relacionados |
| CN107205989A (zh) | 2014-11-14 | 2017-09-26 | 梅琳塔治疗公司 | 治疗、预防或降低皮肤感染风险的方法 |
| WO2018191682A1 (en) * | 2017-04-15 | 2018-10-18 | Melinta Therapeutics, Inc. | Triazole compounds and methods of making and using the same |
| CN110108826A (zh) * | 2019-05-24 | 2019-08-09 | 内蒙古蒙牛乳业（集团）股份有限公司 | 乳或乳制品中氟苯尼考胺的检测方法 |
| US20210371389A1 (en) * | 2020-04-24 | 2021-12-02 | Kansas Soybean Commission | One-step synthesis of soybean polyols |
| US20240076293A1 (en) * | 2020-12-28 | 2024-03-07 | Georgia Tech Research Corporation | Compositions and Methods for Inhibiting Fibrosis, Inflammation and Cancer |
| CN115745823B (zh) * | 2022-11-03 | 2024-02-23 | 武夷学院 | 一种化合物的制备方法及其应用 |
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|---|---|---|---|---|
| US3725385A (en) | 1970-11-02 | 1973-04-03 | Abbott Lab | Process for the demethylation of 3-amino macrolides |
| US4522811A (en) | 1982-07-08 | 1985-06-11 | Syntex (U.S.A.) Inc. | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides |
| MY113693A (en) | 1992-05-26 | 2002-05-31 | Chugai Pharmaceutical Co Ltd | Erythromycin derivatives having an enterokinesis stimulating action |
| US6927057B2 (en) | 1993-09-20 | 2005-08-09 | Kosan Biosciences | Macrolide analogs |
| US5763263A (en) | 1995-11-27 | 1998-06-09 | Dehlinger; Peter J. | Method and apparatus for producing position addressable combinatorial libraries |
| DE19604223A1 (de) * | 1996-02-06 | 1997-08-07 | Bayer Ag | Neue substituierte Oxazolidinone |
| BR9812577A (pt) | 1997-09-30 | 2000-10-17 | Abbott Lab | Composto, processo para preparar o mesmo, composição farmacêutica, e, processo para tratar infecções bacterianas |
| US6124269A (en) | 1997-10-29 | 2000-09-26 | Abbott Laboratories | 2-Halo-6-O-substituted ketolide derivatives |
| AR043071A1 (es) | 1997-10-31 | 2005-07-20 | Abbott Lab | Uso de macrolidos para el tratamiento del cancer y degeneracion macular y una composicion farmaceutica |
| US6288234B1 (en) | 1998-06-08 | 2001-09-11 | Advanced Medicine, Inc. | Multibinding inhibitors of microsomal triglyceride transferase protein |
| IT1301968B1 (it) | 1998-07-30 | 2000-07-20 | Zambon Spa | Derivati di eritromicina ad attivita' antibiotica |
| GB9821938D0 (en) | 1998-10-09 | 1998-12-02 | Zeneca Ltd | Chemical compounds |
| HRP980646B1 (en) | 1998-12-30 | 2008-02-29 | GlaxoSmithKline istra�iva�ki centar Zagreb d.o.o. | Novel oleandomycin derivatives |
| US6939861B2 (en) | 1999-04-16 | 2005-09-06 | Kosan Biosciences, Inc. | Amido macrolides |
| US6451768B1 (en) | 1999-04-16 | 2002-09-17 | Kosan Biosciences, Inc. | Macrolide antiinfective agents |
| US6514944B2 (en) | 1999-04-16 | 2003-02-04 | Kosan Biosciences, Inc. | Macrolide antiinfective agents |
| US6413981B1 (en) | 1999-08-12 | 2002-07-02 | Ortho-Mcneil Pharamceutical, Inc. | Bicyclic heterocyclic substituted phenyl oxazolidinone antibacterials, and related compositions and methods |
| EP1101769A3 (en) | 1999-11-18 | 2001-10-24 | Pfizer Products Inc. | Nitrogen containing erythromycin derivatives |
| GB9928568D0 (en) | 1999-12-03 | 2000-02-02 | Zeneca Ltd | Chemical compounds |
| KR20020072311A (ko) | 2000-02-10 | 2002-09-14 | 파마시아 앤드 업존 캄파니 | 피페라진 아미드 치환기를 갖는 옥사졸리디논 티오아미드 |
| WO2001060833A2 (en) | 2000-02-18 | 2001-08-23 | Kosan Biosciences, Inc. | Motilide compounds |
| GB0009803D0 (en) | 2000-04-25 | 2000-06-07 | Astrazeneca Ab | Chemical compounds |
| ATE321770T1 (de) | 2000-08-17 | 2006-04-15 | Kitasato Inst | Pseudoerythromycin-derivate |
| JP4162992B2 (ja) | 2000-08-22 | 2008-10-08 | バジリア ファルマスーチカ アーゲー | 抗菌活性を有する新規マクロライド |
| CA2429709A1 (en) | 2000-12-01 | 2002-07-04 | Gary Ashley | Motilide compounds |
| CA2451391A1 (en) | 2001-07-03 | 2003-01-16 | Chiron Corporation | C12 modified erythromycin macrolides and ketolides having antibacterial activity |
| SI1427711T1 (sl) | 2001-09-11 | 2005-12-31 | Astrazeneca Ab | Oksazolidinonski in/ali izoksazolinski derivati kot antibakterijska sredstva |
| EP1443930A1 (en) | 2001-10-25 | 2004-08-11 | AstraZeneca AB | Isoxazoline derivatives useful as antimicrobials |
| JP2005538927A (ja) | 2002-01-17 | 2005-12-22 | コーザン バイオサイエンシス インコーポレイテッド | アミドマクロライド |
| US8063021B2 (en) | 2002-01-17 | 2011-11-22 | Kosan Biosciences Incorporated | Ketolide anti-infective compounds |
| US6992069B2 (en) | 2002-04-30 | 2006-01-31 | Yu-Gui Gu | Tricyclic macrolide antibacterial compounds |
| US20050045585A1 (en) * | 2002-05-07 | 2005-03-03 | Gang Zhang | Method of electrochemically fabricating multilayer structures having improved interlayer adhesion |
| JP4638225B2 (ja) * | 2002-05-30 | 2011-02-23 | ザ スクリプス リサーチ インスティテュート | 銅を触媒とするアジドとアセチレンのライゲーション |
| ITMI20021726A1 (it) * | 2002-08-01 | 2004-02-02 | Zambon Spa | Macrolidi ad attivita' antiinfiammatoria. |
| TW200420573A (en) | 2002-09-26 | 2004-10-16 | Rib X Pharmaceuticals Inc | Bifunctional heterocyclic compounds and methods of making and using same |
| AU2004217919A1 (en) | 2003-03-05 | 2004-09-16 | Rib-X Pharmaceuticals, Inc. | Bifunctional heterocyclic compounds and methods of making and using the same |
| JPWO2004078771A1 (ja) | 2003-03-07 | 2006-06-08 | 大正製薬株式会社 | ２−フルオロ−６−ｏ−置換ケトライド誘導体 |
| EP1638549A4 (en) | 2003-03-10 | 2011-06-15 | Optimer Pharmaceuticals Inc | NEW ANTIBACTERIAL AGENTS |
| CA2523134A1 (en) | 2003-04-25 | 2004-11-11 | Chiron Corporation | Pyridyl substituted ketolide antibiotics |
| US7163924B2 (en) | 2003-04-25 | 2007-01-16 | Chiron Corporation | Ketolide derivatives |
| EP1656370B1 (en) * | 2003-06-03 | 2012-08-15 | Rib-X Pharmaceuticals, Inc. | Biaryl heterocyclic compounds and methods of making and using the same |
| WO2005042554A1 (en) | 2003-10-30 | 2005-05-12 | Rib-X Pharmaceuticals, Inc. | Bifunctional macrolide heterocyclic compounds and methods of making and using the same |
| US20070270357A1 (en) | 2003-11-18 | 2007-11-22 | Farmer Jay J | Bifunctional Macrolide Heterocyclic Compounds and Methods of Making and Using the Same |
| AU2003304705A1 (en) | 2003-12-24 | 2005-08-03 | Enanta Pharmaceuticals, Inc. | 11-csubsituted erythromycin derivatives |
| EP1723159B1 (en) * | 2004-02-27 | 2019-06-12 | Melinta Therapeutics, Inc. | Macrocyclic compounds and methods of making and using the same |
| WO2005118610A2 (en) | 2004-06-01 | 2005-12-15 | Rib-X Pharmaceuticals, Inc. | Macrocyclic compounds and methods of making and using the same |
| US7402568B2 (en) | 2004-09-29 | 2008-07-22 | Enanta Pharmaceuticals, Inc. | Bicyclic 9a-azalide derivatives |
| US7419962B2 (en) | 2004-12-07 | 2008-09-02 | Enanta Pharmaceuticals, Inc. | 3,6-bicyclolides |
| US7229972B2 (en) | 2004-12-07 | 2007-06-12 | Enanta Pharmaceuticals, Inc. | 3,6-Bicyclolides |
| WO2006065743A2 (en) | 2004-12-13 | 2006-06-22 | Enanta Pharmaceuticals, Inc. | Tetracylic bicyclolides |
| UA85937C2 (uk) | 2004-12-21 | 2009-03-10 | Пфайзер Продактс Інк. | Макроліди |
| US7271155B2 (en) | 2005-01-07 | 2007-09-18 | Enanta Pharmaceuticals, Inc. | 9A, 11-2C-bicyclic 9a-azalide derivatives |
| EP3290427A1 (en) * | 2005-08-24 | 2018-03-07 | Melinta Therapeutics, Inc. | Triazole compounds and methods of making and using the same |
| EP1934237A2 (en) | 2005-08-24 | 2008-06-25 | Rib-X Pharmaceuticals, Inc. | Triazole compounds and methods of making and using the same |
-
2006
- 2006-08-24 EP EP17178221.2A patent/EP3290427A1/en not_active Withdrawn
- 2006-08-24 WO PCT/US2006/033645 patent/WO2007025284A1/en not_active Ceased
- 2006-08-24 JP JP2008528247A patent/JP5395432B2/ja not_active Expired - Fee Related
- 2006-08-24 EP EP06802533.7A patent/EP1934238B1/en not_active Not-in-force
- 2006-08-24 JP JP2008528168A patent/JP2009506066A/ja not_active Withdrawn
- 2006-08-24 EP EP06824847A patent/EP1928893A2/en not_active Withdrawn
- 2006-08-24 DK DK06802533.7T patent/DK1934238T3/en active
- 2006-08-24 HR HRP20171285TT patent/HRP20171285T1/hr unknown
- 2006-08-24 ES ES06802533T patent/ES2638427T3/es active Active
- 2006-08-24 US US11/990,883 patent/US8278281B2/en not_active Expired - Fee Related
- 2006-08-24 WO PCT/US2006/033170 patent/WO2007025098A2/en not_active Ceased
-
2012
- 2012-09-14 US US13/616,962 patent/US20130065845A1/en not_active Abandoned
-
2013
- 2013-08-19 JP JP2013169594A patent/JP5981401B2/ja not_active Expired - Fee Related
- 2013-08-21 US US13/972,732 patent/US9006189B2/en not_active Expired - Fee Related
-
2015
- 2015-03-18 US US14/661,863 patent/US20160031926A1/en not_active Abandoned
- 2015-11-16 JP JP2015223733A patent/JP2016094421A/ja active Pending
-
2017
- 2017-05-17 US US15/597,701 patent/US20180094016A1/en not_active Abandoned
- 2017-07-21 JP JP2017141745A patent/JP2018008970A/ja active Pending
-
2018
- 2018-09-11 JP JP2018169395A patent/JP2019023194A/ja active Pending
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