JP2009506075A5 - - Google Patents
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- Publication number
- JP2009506075A5 JP2009506075A5 JP2008528247A JP2008528247A JP2009506075A5 JP 2009506075 A5 JP2009506075 A5 JP 2009506075A5 JP 2008528247 A JP2008528247 A JP 2008528247A JP 2008528247 A JP2008528247 A JP 2008528247A JP 2009506075 A5 JP2009506075 A5 JP 2009506075A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- unsaturated
- aromatic
- saturated
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 CC(*)C(*)*NC(*)(*=C)O Chemical compound CC(*)C(*)*NC(*)(*=C)O 0.000 description 4
- DICNFKINDZVTAN-DDJNEFBRSA-N CC([C@@H]([C@@](C)(C1)OC)[O]=C)O[C@H]1O[C@@H]([C@H](C)[C@@H](C)[C@@](C)(C[C@@H](C)C([C@H](C)C([C@@](C)(CO1)O)[O]=C)=O)OC)C(C)C1=O Chemical compound CC([C@@H]([C@@](C)(C1)OC)[O]=C)O[C@H]1O[C@@H]([C@H](C)[C@@H](C)[C@@](C)(C[C@@H](C)C([C@H](C)C([C@@](C)(CO1)O)[O]=C)=O)OC)C(C)C1=O DICNFKINDZVTAN-DDJNEFBRSA-N 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US71144305P | 2005-08-24 | 2005-08-24 | |
| US60/711,443 | 2005-08-24 | ||
| US76290706P | 2006-01-26 | 2006-01-26 | |
| US60/762,907 | 2006-01-26 | ||
| PCT/US2006/033645 WO2007025284A1 (en) | 2005-08-24 | 2006-08-24 | Triazole compounds and methods of making and using the same |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013169594A Division JP5981401B2 (ja) | 2005-08-24 | 2013-08-19 | トリアゾール化合物ならびにこれを作製する方法および使用する方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009506075A JP2009506075A (ja) | 2009-02-12 |
| JP2009506075A5 true JP2009506075A5 (https=) | 2009-10-08 |
| JP5395432B2 JP5395432B2 (ja) | 2014-01-22 |
Family
ID=37467427
Family Applications (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008528247A Expired - Fee Related JP5395432B2 (ja) | 2005-08-24 | 2006-08-24 | トリアゾール化合物ならびにこれを作製する方法および使用する方法 |
| JP2008528168A Withdrawn JP2009506066A (ja) | 2005-08-24 | 2006-08-24 | トリアゾール化合物ならびにこれを作製する方法および使用する方法 |
| JP2013169594A Expired - Fee Related JP5981401B2 (ja) | 2005-08-24 | 2013-08-19 | トリアゾール化合物ならびにこれを作製する方法および使用する方法 |
| JP2015223733A Pending JP2016094421A (ja) | 2005-08-24 | 2015-11-16 | トリアゾール化合物ならびにこれを作製する方法および使用する方法 |
| JP2017141745A Pending JP2018008970A (ja) | 2005-08-24 | 2017-07-21 | トリアゾール化合物ならびにこれを作製する方法および使用する方法 |
| JP2018169395A Pending JP2019023194A (ja) | 2005-08-24 | 2018-09-11 | トリアゾール化合物ならびにこれを作製する方法および使用する方法 |
Family Applications After (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008528168A Withdrawn JP2009506066A (ja) | 2005-08-24 | 2006-08-24 | トリアゾール化合物ならびにこれを作製する方法および使用する方法 |
| JP2013169594A Expired - Fee Related JP5981401B2 (ja) | 2005-08-24 | 2013-08-19 | トリアゾール化合物ならびにこれを作製する方法および使用する方法 |
| JP2015223733A Pending JP2016094421A (ja) | 2005-08-24 | 2015-11-16 | トリアゾール化合物ならびにこれを作製する方法および使用する方法 |
| JP2017141745A Pending JP2018008970A (ja) | 2005-08-24 | 2017-07-21 | トリアゾール化合物ならびにこれを作製する方法および使用する方法 |
| JP2018169395A Pending JP2019023194A (ja) | 2005-08-24 | 2018-09-11 | トリアゾール化合物ならびにこれを作製する方法および使用する方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (5) | US8278281B2 (https=) |
| EP (3) | EP3290427A1 (https=) |
| JP (6) | JP5395432B2 (https=) |
| DK (1) | DK1934238T3 (https=) |
| ES (1) | ES2638427T3 (https=) |
| HR (1) | HRP20171285T1 (https=) |
| WO (2) | WO2007025284A1 (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5383037B2 (ja) | 2004-02-27 | 2014-01-08 | リブ−エックス ファーマシューティカルズ，インコーポレイテッド | 大環状化合物およびそれらを製造し使用する方法 |
| JP2009506063A (ja) | 2005-08-24 | 2009-02-12 | リブ−エックス ファーマシューティカルズ，インコーポレイテッド | トリアゾール化合物ならびにこれを作製する方法および使用する方法 |
| EP3290427A1 (en) * | 2005-08-24 | 2018-03-07 | Melinta Therapeutics, Inc. | Triazole compounds and methods of making and using the same |
| WO2008106224A1 (en) * | 2007-02-28 | 2008-09-04 | Rib-X Pharmaceuticals, Inc. | Macrolide compounds and methods of making and using the same |
| EP2176216B1 (en) * | 2007-07-06 | 2012-04-25 | Paratek Pharmaceuticals, Inc. | Methods for synthesizing 9-substituted minocycline |
| JP2011026260A (ja) * | 2009-07-28 | 2011-02-10 | Central Glass Co Ltd | ３位に脱離基を有する２−フルオロプロピルアミン保護体または該アミンｎ−アルキル保護体 |
| CN101619085B (zh) * | 2009-08-11 | 2015-04-22 | 沈阳药科大学 | 红霉素衍生物及其作为肿瘤细胞增殖抑制剂的用途 |
| AR092278A1 (es) * | 2012-08-31 | 2015-04-08 | Novartis Ag | Proceso de obtencion de derivados n-acilicos de bifenil-alanina e intermediarios relacionados |
| HK1244211A1 (zh) | 2014-11-14 | 2018-08-03 | Melinta Therapeutics, Inc. | 治疗、预防或降低皮肤感染风险的方法 |
| WO2018191682A1 (en) * | 2017-04-15 | 2018-10-18 | Melinta Therapeutics, Inc. | Triazole compounds and methods of making and using the same |
| CN110108826A (zh) * | 2019-05-24 | 2019-08-09 | 内蒙古蒙牛乳业（集团）股份有限公司 | 乳或乳制品中氟苯尼考胺的检测方法 |
| US20210371389A1 (en) * | 2020-04-24 | 2021-12-02 | Kansas Soybean Commission | One-step synthesis of soybean polyols |
| WO2022146980A1 (en) | 2020-12-28 | 2022-07-07 | Georgia Tech Research Corporation | Compositions and methods for inhibiting fibrosis, inflammation and cancer |
| CN115745823B (zh) * | 2022-11-03 | 2024-02-23 | 武夷学院 | 一种化合物的制备方法及其应用 |
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|---|---|---|---|---|
| US3725385A (en) | 1970-11-02 | 1973-04-03 | Abbott Lab | Process for the demethylation of 3-amino macrolides |
| US4522811A (en) | 1982-07-08 | 1985-06-11 | Syntex (U.S.A.) Inc. | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides |
| MY113693A (en) | 1992-05-26 | 2002-05-31 | Chugai Pharmaceutical Co Ltd | Erythromycin derivatives having an enterokinesis stimulating action |
| US6927057B2 (en) | 1993-09-20 | 2005-08-09 | Kosan Biosciences | Macrolide analogs |
| US5763263A (en) | 1995-11-27 | 1998-06-09 | Dehlinger; Peter J. | Method and apparatus for producing position addressable combinatorial libraries |
| DE19604223A1 (de) * | 1996-02-06 | 1997-08-07 | Bayer Ag | Neue substituierte Oxazolidinone |
| DK1025114T3 (da) * | 1997-09-30 | 2004-07-05 | Abbott Lab | 3'-N-modificerede 6-O-substituerede erythromycin-ketolidderivater med antibakteriel aktivitet |
| US6124269A (en) | 1997-10-29 | 2000-09-26 | Abbott Laboratories | 2-Halo-6-O-substituted ketolide derivatives |
| ZA989885B (en) | 1997-10-31 | 1999-05-05 | Abbott Lab | Use of macrolides for the treatment of cancer and macular degeneration |
| WO1999063929A2 (en) | 1998-06-08 | 1999-12-16 | Advanced Medicine, Inc. | Multibinding inhibitors of microsomal triglyceride transferase protein |
| IT1301968B1 (it) | 1998-07-30 | 2000-07-20 | Zambon Spa | Derivati di eritromicina ad attivita' antibiotica |
| GB9821938D0 (en) | 1998-10-09 | 1998-12-02 | Zeneca Ltd | Chemical compounds |
| HRP980646B1 (en) | 1998-12-30 | 2008-02-29 | GlaxoSmithKline istra�iva�ki centar Zagreb d.o.o. | Novel oleandomycin derivatives |
| US6514944B2 (en) | 1999-04-16 | 2003-02-04 | Kosan Biosciences, Inc. | Macrolide antiinfective agents |
| US6939861B2 (en) | 1999-04-16 | 2005-09-06 | Kosan Biosciences, Inc. | Amido macrolides |
| US6451768B1 (en) | 1999-04-16 | 2002-09-17 | Kosan Biosciences, Inc. | Macrolide antiinfective agents |
| US6413981B1 (en) | 1999-08-12 | 2002-07-02 | Ortho-Mcneil Pharamceutical, Inc. | Bicyclic heterocyclic substituted phenyl oxazolidinone antibacterials, and related compositions and methods |
| EP1101769A3 (en) | 1999-11-18 | 2001-10-24 | Pfizer Products Inc. | Nitrogen containing erythromycin derivatives |
| GB9928568D0 (en) | 1999-12-03 | 2000-02-02 | Zeneca Ltd | Chemical compounds |
| JP2003522763A (ja) | 2000-02-10 | 2003-07-29 | ファルマシア・アンド・アップジョン・カンパニー | ピペラジンアミド置換基を持つオキサゾリジノンチオアミド |
| CA2399198A1 (en) | 2000-02-18 | 2001-08-23 | Christopher Carreras | Motilide compounds |
| GB0009803D0 (en) | 2000-04-25 | 2000-06-07 | Astrazeneca Ab | Chemical compounds |
| ATE321770T1 (de) | 2000-08-17 | 2006-04-15 | Kitasato Inst | Pseudoerythromycin-derivate |
| BR0113472A (pt) | 2000-08-22 | 2003-07-01 | Basilea Pharmaceutica Ag | Macrolìdeos com atividade antibacteriana |
| AU2002225724A1 (en) | 2000-12-01 | 2002-07-08 | Kosan Biosciences, Inc. | Motilide compounds |
| WO2003004509A2 (en) | 2001-07-03 | 2003-01-16 | Chiron Corporation | C12 modified erythromycin macrolides and ketolides having antibacterial activity |
| US7396847B2 (en) | 2001-09-11 | 2008-07-08 | Astrazeneca Ab | Oxazolidinone and/or isoxazoline as antibacterial agents |
| EP1443930A1 (en) | 2001-10-25 | 2004-08-11 | AstraZeneca AB | Isoxazoline derivatives useful as antimicrobials |
| JP2005538927A (ja) | 2002-01-17 | 2005-12-22 | コーザン バイオサイエンシス インコーポレイテッド | アミドマクロライド |
| US8063021B2 (en) | 2002-01-17 | 2011-11-22 | Kosan Biosciences Incorporated | Ketolide anti-infective compounds |
| US6992069B2 (en) | 2002-04-30 | 2006-01-31 | Yu-Gui Gu | Tricyclic macrolide antibacterial compounds |
| US20050045585A1 (en) * | 2002-05-07 | 2005-03-03 | Gang Zhang | Method of electrochemically fabricating multilayer structures having improved interlayer adhesion |
| AU2003240482B2 (en) * | 2002-05-30 | 2009-03-12 | The Scripps Research Institute | Copper-catalysed ligation of azides and acetylenes |
| ITMI20021726A1 (it) | 2002-08-01 | 2004-02-02 | Zambon Spa | Macrolidi ad attivita' antiinfiammatoria. |
| AR043050A1 (es) * | 2002-09-26 | 2005-07-13 | Rib X Pharmaceuticals Inc | Compuestos heterociclicos bifuncionales y metodos para preparar y usar los mismos |
| CN1780846A (zh) | 2003-03-05 | 2006-05-31 | Rib－X医药品有限公司 | 双官能杂环化合物及其制备和使用方法 |
| WO2004078771A1 (ja) | 2003-03-07 | 2004-09-16 | Taisho Pharmaceutical Co., Ltd. | ２－フルオロ－６－ｏ－置換ケトライド誘導体 |
| ES2552682T3 (es) | 2003-03-10 | 2015-12-01 | Merck Sharp & Dohme Corp. | Agentes antibacterianos novedosos |
| US7163924B2 (en) | 2003-04-25 | 2007-01-16 | Chiron Corporation | Ketolide derivatives |
| US7332476B2 (en) | 2003-04-25 | 2008-02-19 | Novartis Ag | Pyridyl substituted ketolide antibiotics |
| JP5043428B2 (ja) * | 2003-06-03 | 2012-10-10 | リブ−エックス ファーマシューティカルズ，インコーポレイテッド | ビアリール複素環式化合物ならびにその製造および使用方法 |
| WO2005042554A1 (en) | 2003-10-30 | 2005-05-12 | Rib-X Pharmaceuticals, Inc. | Bifunctional macrolide heterocyclic compounds and methods of making and using the same |
| JP2007512256A (ja) | 2003-11-18 | 2007-05-17 | リブ−エックス ファーマシューティカルズ，インコーポレイテッド | 二官能性マクロライド複素環化合物ならびにこれらを製造する方法およびこれらを使用する方法 |
| WO2005067919A1 (en) | 2003-12-24 | 2005-07-28 | Enanta Pharmaceuticals, Inc. | 11-csubsituted erythromycin derivatives |
| JP5383037B2 (ja) * | 2004-02-27 | 2014-01-08 | リブ−エックス ファーマシューティカルズ，インコーポレイテッド | 大環状化合物およびそれらを製造し使用する方法 |
| WO2005118610A2 (en) | 2004-06-01 | 2005-12-15 | Rib-X Pharmaceuticals, Inc. | Macrocyclic compounds and methods of making and using the same |
| US7402568B2 (en) | 2004-09-29 | 2008-07-22 | Enanta Pharmaceuticals, Inc. | Bicyclic 9a-azalide derivatives |
| US7419962B2 (en) | 2004-12-07 | 2008-09-02 | Enanta Pharmaceuticals, Inc. | 3,6-bicyclolides |
| US7229972B2 (en) | 2004-12-07 | 2007-06-12 | Enanta Pharmaceuticals, Inc. | 3,6-Bicyclolides |
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| UA85937C2 (uk) | 2004-12-21 | 2009-03-10 | Пфайзер Продактс Інк. | Макроліди |
| US7271155B2 (en) | 2005-01-07 | 2007-09-18 | Enanta Pharmaceuticals, Inc. | 9A, 11-2C-bicyclic 9a-azalide derivatives |
| EP3290427A1 (en) * | 2005-08-24 | 2018-03-07 | Melinta Therapeutics, Inc. | Triazole compounds and methods of making and using the same |
| JP2009506063A (ja) * | 2005-08-24 | 2009-02-12 | リブ−エックス ファーマシューティカルズ，インコーポレイテッド | トリアゾール化合物ならびにこれを作製する方法および使用する方法 |
-
2006
- 2006-08-24 EP EP17178221.2A patent/EP3290427A1/en not_active Withdrawn
- 2006-08-24 EP EP06824847A patent/EP1928893A2/en not_active Withdrawn
- 2006-08-24 HR HRP20171285TT patent/HRP20171285T1/hr unknown
- 2006-08-24 DK DK06802533.7T patent/DK1934238T3/en active
- 2006-08-24 WO PCT/US2006/033645 patent/WO2007025284A1/en not_active Ceased
- 2006-08-24 JP JP2008528247A patent/JP5395432B2/ja not_active Expired - Fee Related
- 2006-08-24 ES ES06802533T patent/ES2638427T3/es active Active
- 2006-08-24 JP JP2008528168A patent/JP2009506066A/ja not_active Withdrawn
- 2006-08-24 EP EP06802533.7A patent/EP1934238B1/en not_active Not-in-force
- 2006-08-24 US US11/990,883 patent/US8278281B2/en not_active Expired - Fee Related
- 2006-08-24 WO PCT/US2006/033170 patent/WO2007025098A2/en not_active Ceased
-
2012
- 2012-09-14 US US13/616,962 patent/US20130065845A1/en not_active Abandoned
-
2013
- 2013-08-19 JP JP2013169594A patent/JP5981401B2/ja not_active Expired - Fee Related
- 2013-08-21 US US13/972,732 patent/US9006189B2/en not_active Expired - Fee Related
-
2015
- 2015-03-18 US US14/661,863 patent/US20160031926A1/en not_active Abandoned
- 2015-11-16 JP JP2015223733A patent/JP2016094421A/ja active Pending
-
2017
- 2017-05-17 US US15/597,701 patent/US20180094016A1/en not_active Abandoned
- 2017-07-21 JP JP2017141745A patent/JP2018008970A/ja active Pending
-
2018
- 2018-09-11 JP JP2018169395A patent/JP2019023194A/ja active Pending
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