JP2009191078A5 - - Google Patents

Download PDF

Info

Publication number
JP2009191078A5
JP2009191078A5 JP2009133383A JP2009133383A JP2009191078A5 JP 2009191078 A5 JP2009191078 A5 JP 2009191078A5 JP 2009133383 A JP2009133383 A JP 2009133383A JP 2009133383 A JP2009133383 A JP 2009133383A JP 2009191078 A5 JP2009191078 A5 JP 2009191078A5
Authority
JP
Japan
Prior art keywords
peptide
derivative
epitope
heart disease
ischemic heart
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2009133383A
Other languages
English (en)
Japanese (ja)
Other versions
JP2009191078A (ja
JP5270456B2 (ja
Filing date
Publication date
Priority claimed from SE0101232A external-priority patent/SE0101232D0/xx
Priority claimed from SE0103754A external-priority patent/SE0103754L/xx
Application filed filed Critical
Publication of JP2009191078A publication Critical patent/JP2009191078A/ja
Publication of JP2009191078A5 publication Critical patent/JP2009191078A5/ja
Application granted granted Critical
Publication of JP5270456B2 publication Critical patent/JP5270456B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP2009133383A 2001-04-05 2009-06-02 アテローム性動脈硬化症の治療のためのペプチドに基づいた免疫治療、及び酸化した低密度リポ蛋白質に対する免疫応答の測定のためのペプチドベースのアッセーの開発 Expired - Fee Related JP5270456B2 (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
SE0101232-7 2001-04-05
SE0101232A SE0101232D0 (sv) 2001-04-05 2001-04-05 Peptide-based immunization therapy for treatment of atherosclerosis and development of peptide-based elisa for determination of immune responses against oxidized low density liprotein
SE0103754A SE0103754L (sv) 2001-04-05 2001-11-09 Peptider från apolipoprotein B, användning därav immunisering, diagnosmetod eller terapeutisk behandling av ischemiska kardiovaskulära sjukdomar, samt farmaceutisk komposition och vaccin innehållande sådan peptid
SE0103754-8 2001-11-09

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2002578993A Division JP2004529143A (ja) 2001-04-05 2002-04-05 アテローム性動脈硬化症の治療のためのペプチドに基づいた免疫治療、及び酸化した低密度リポ蛋白質に対する免疫応答の測定のためのペプチドベースのアッセーの開発

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2013034312A Division JP5613890B2 (ja) 2001-04-05 2013-02-25 アテローム性動脈硬化症の治療のためのペプチドに基づいた免疫治療、及び酸化した低密度リポ蛋白質に対する免疫応答の測定のためのペプチドベースのアッセーの開発

Publications (3)

Publication Number Publication Date
JP2009191078A JP2009191078A (ja) 2009-08-27
JP2009191078A5 true JP2009191078A5 (enExample) 2011-06-16
JP5270456B2 JP5270456B2 (ja) 2013-08-21

Family

ID=26655437

Family Applications (6)

Application Number Title Priority Date Filing Date
JP2002578993A Withdrawn JP2004529143A (ja) 2001-04-05 2002-04-05 アテローム性動脈硬化症の治療のためのペプチドに基づいた免疫治療、及び酸化した低密度リポ蛋白質に対する免疫応答の測定のためのペプチドベースのアッセーの開発
JP2008015545A Withdrawn JP2008169215A (ja) 2001-04-05 2008-01-25 アテローム性動脈硬化症の治療のためのペプチドに基づいた免疫治療、及び酸化した低密度リポ蛋白質に対する免疫応答の測定のためのペプチドベースのアッセーの開発
JP2009133383A Expired - Fee Related JP5270456B2 (ja) 2001-04-05 2009-06-02 アテローム性動脈硬化症の治療のためのペプチドに基づいた免疫治療、及び酸化した低密度リポ蛋白質に対する免疫応答の測定のためのペプチドベースのアッセーの開発
JP2010239478A Expired - Lifetime JP5300820B2 (ja) 2001-04-05 2010-10-26 アテローム性動脈硬化症の治療のためのペプチドに基づいた免疫治療、及び酸化した低密度リポ蛋白質に対する免疫応答の測定のためのペプチドベースのアッセーの開発
JP2010239477A Expired - Lifetime JP5300819B2 (ja) 2001-04-05 2010-10-26 アテローム性動脈硬化症の治療のためのペプチドに基づいた免疫治療、及び酸化した低密度リポ蛋白質に対する免疫応答の測定のためのペプチドベースのアッセーの開発
JP2013034312A Expired - Lifetime JP5613890B2 (ja) 2001-04-05 2013-02-25 アテローム性動脈硬化症の治療のためのペプチドに基づいた免疫治療、及び酸化した低密度リポ蛋白質に対する免疫応答の測定のためのペプチドベースのアッセーの開発

Family Applications Before (2)

Application Number Title Priority Date Filing Date
JP2002578993A Withdrawn JP2004529143A (ja) 2001-04-05 2002-04-05 アテローム性動脈硬化症の治療のためのペプチドに基づいた免疫治療、及び酸化した低密度リポ蛋白質に対する免疫応答の測定のためのペプチドベースのアッセーの開発
JP2008015545A Withdrawn JP2008169215A (ja) 2001-04-05 2008-01-25 アテローム性動脈硬化症の治療のためのペプチドに基づいた免疫治療、及び酸化した低密度リポ蛋白質に対する免疫応答の測定のためのペプチドベースのアッセーの開発

Family Applications After (3)

Application Number Title Priority Date Filing Date
JP2010239478A Expired - Lifetime JP5300820B2 (ja) 2001-04-05 2010-10-26 アテローム性動脈硬化症の治療のためのペプチドに基づいた免疫治療、及び酸化した低密度リポ蛋白質に対する免疫応答の測定のためのペプチドベースのアッセーの開発
JP2010239477A Expired - Lifetime JP5300819B2 (ja) 2001-04-05 2010-10-26 アテローム性動脈硬化症の治療のためのペプチドに基づいた免疫治療、及び酸化した低密度リポ蛋白質に対する免疫応答の測定のためのペプチドベースのアッセーの開発
JP2013034312A Expired - Lifetime JP5613890B2 (ja) 2001-04-05 2013-02-25 アテローム性動脈硬化症の治療のためのペプチドに基づいた免疫治療、及び酸化した低密度リポ蛋白質に対する免疫応答の測定のためのペプチドベースのアッセーの開発

Country Status (18)

Country Link
EP (42) EP2295464B1 (enExample)
JP (6) JP2004529143A (enExample)
CN (4) CN103122031B (enExample)
AT (2) ATE415423T1 (enExample)
AU (1) AU2002246484B8 (enExample)
BR (1) BR0208685A (enExample)
CA (3) CA2827167A1 (enExample)
CY (1) CY1108817T1 (enExample)
DE (1) DE60230029D1 (enExample)
DK (3) DK2295464T3 (enExample)
EE (2) EE200700052A (enExample)
ES (2) ES2546293T3 (enExample)
IL (4) IL158285A0 (enExample)
PL (4) PL217858B1 (enExample)
PT (1) PT1383526E (enExample)
RU (1) RU2296582C2 (enExample)
SE (1) SE0103754L (enExample)
WO (1) WO2002080954A1 (enExample)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030105003A1 (en) 2001-04-05 2003-06-05 Jan Nilsson Peptide-based immunization therapy for treatment of atherosclerosis and development of peptide-based assay for determination of immune responses against oxidized low density lipoprotein
SE0103754L (sv) * 2001-04-05 2002-10-06 Forskarpatent I Syd Ab Peptider från apolipoprotein B, användning därav immunisering, diagnosmetod eller terapeutisk behandling av ischemiska kardiovaskulära sjukdomar, samt farmaceutisk komposition och vaccin innehållande sådan peptid
CN1283313C (zh) 2001-09-28 2006-11-08 埃斯佩里安医疗公司 α螺旋状载脂蛋白或HDL关联蛋白在制备局部给药预防和治疗再狭窄的药物中的用途
SE0302312D0 (sv) * 2002-10-04 2003-08-27 Forskarpatent I Syd Ab Peptide-based passive immunization therapy for treatment of atherosclerosis
CA2500895A1 (en) * 2002-10-04 2004-04-15 Forskarpatent I Syd Ab Peptide-based passive immunization therapy for treatment of atherosclerosis
SE0302422D0 (sv) 2003-09-11 2003-09-11 Forskarpatent I Syd Ab Peptide-based immunization therapy for treatment of atherosclerosis
SE0400683D0 (sv) 2004-03-19 2004-03-19 Forskarpatent I Syd Ab Use of modified extracellular matrix proteins in diagnosis and treatment of a atherosclerosis
WO2005097206A2 (en) 2004-04-06 2005-10-20 Cedars-Sinai Medical Center Prevention and treatment of vascular disease with recombinant adeno-associated virus vectors encoding apolipoprotein a-i and apolipoprotein a-i milano
PL1797893T3 (pl) * 2004-04-15 2010-09-30 Athera Biotechnologies Ab Przeciwciała przeciwko koniugatom fosforylocholiny
EP1676602A1 (en) * 2005-01-04 2006-07-05 Institut National De La Sante Et De La Recherche Medicale (Inserm) Continuous administration of epitopes derived from protein present in atherosclerotic plaque for the treatment of atherosclerosis
GB0517878D0 (en) 2005-09-02 2005-10-12 Bioinvent Int Ab Immunotherapeutic treatment
MX2009006744A (es) * 2006-12-22 2009-06-30 Abbott Lab Panel de padecimiento cardiovascular autoinmune y metodos de utilizacion del mismo.
WO2008104194A1 (en) * 2007-02-28 2008-09-04 Bioinvent International Ab Oxidized ldl and antibodies thereto for the treatment of atheroscleroti c plaques
AU2008225766B2 (en) 2007-03-15 2012-06-07 Novartis Ag Organic compounds and their uses
CN108196072A (zh) * 2007-11-05 2018-06-22 北欧生物科技公司 用于进行cvd风险评估的生物化学标志物
US20100041663A1 (en) 2008-07-18 2010-02-18 Novartis Ag Organic Compounds as Smo Inhibitors
KR101506314B1 (ko) * 2008-08-15 2015-04-06 후지쿠라 가세이 가부시키가이샤 동맥경화 진단용 폴리펩티드 마커, 및 상기 마커 등을 이용한 동맥 경화의 검출방법, 및 동맥경화 진단용 키트
AU2010319323B2 (en) 2009-11-14 2015-01-15 Cardiovax, Llc Immunomodulatory methods and systems for treatment and/or prevention of atherosclerosis
US8506964B2 (en) * 2010-02-05 2013-08-13 Cardiovax, Llc Fusion proteins and related compositions, methods and systems for treatment and/or prevention of atherosclerosis
US20130142760A1 (en) 2010-08-18 2013-06-06 Cedars-Sinai Medical Center Atherosclerosis inhibition via modulation of monocyte-macrophage phenotype using apo a-i milano gene transfer
AU2011336997A1 (en) * 2010-11-12 2013-05-30 Cedars-Sinai Medical Center Immunomodulatory methods and systems for treatment and/or prevention of hypertension
US20130302362A1 (en) * 2010-11-12 2013-11-14 Cedars-Sinai Medical Center Immunomodulatory Compositions, Methods and Systems Comprising Immunogenic Fragments of ApoB-100
EP2637685A1 (en) * 2010-11-12 2013-09-18 Cedars-Sinai Medical Center Immunomodulatory methods and systems for treatment and/or prevention of aneurysms
EP2742068B1 (en) 2011-08-09 2019-04-03 Athera Biotechnologies AB New antibodies against phosphorylcholine
EP2741770A4 (en) 2011-08-09 2014-12-31 Athera Biotechnologies Ab ANTIBODY BINDING TO PHOSPHORYLCHOLIN (PC) AND / OR PC CONJUGATES
RU2495048C1 (ru) * 2012-04-18 2013-10-10 Андрей Валентинович Исаев Пептид, обладающий антиатеросклеротическим действием и композиция для профилактики и лечения атеросклероза сосудов
CN104768970B (zh) * 2012-11-06 2019-11-15 日内瓦大学 模拟肽
CN103520713B (zh) * 2013-10-16 2015-10-28 西北农林科技大学 一种ApoB100酵母重组疫苗及其制备方法和应用
CN103860470A (zh) * 2014-03-05 2014-06-18 贵州中泰生物科技有限公司 一种口服高密度脂蛋白脂质体的制备方法
CN105315364B (zh) * 2014-06-17 2018-09-18 广州文瑞生物科技有限公司 胶原蛋白vi疫苗预防动脉粥样硬化
CN114085283A (zh) * 2015-05-19 2022-02-25 拉·约拉过敏反应及免疫医学研究所 调节炎症应答及治疗不良心血管事件、病和粥样硬化的人apob100表位、方法和用途
US10858422B2 (en) 2016-05-31 2020-12-08 Abcentra, Llc Methods for treating systemic lupus erythematosus with an anti-apolipoprotein B antibody
CN108478817B (zh) * 2018-03-16 2020-10-27 北京大学 一种动脉粥样硬化检测试剂及其制备方法
JP7357646B2 (ja) 2018-05-29 2023-10-06 アブセントラ，エルエルシー 乾癬の治療のための組成物及び方法
CA3129373A1 (en) 2018-05-29 2019-12-05 Abcentra, Llc Compositions and methods for treatment of rheumatoid arthritis and accelerated atherosclerosis
CN115025210B (zh) * 2021-03-05 2025-09-05 香港中文大学 减少动脉粥样硬化进展的肽疫苗组合物和药物制剂
CN115025211A (zh) * 2021-11-02 2022-09-09 南京理工大学 用于动脉粥样硬化治疗的纳米疫苗及其制备方法

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4970144A (en) 1984-12-31 1990-11-13 International Genetic Engineering Peptide fragments of human apolipoprotein, type-specific antibodies and methods of use
US5972890A (en) 1988-05-02 1999-10-26 New England Deaconess Hospital Corporation Synthetic peptides for arterial imaging
WO1993018067A1 (en) * 1992-03-06 1993-09-16 Abbott Laboratories Immunocapture assay for direct quantitation of specific lipoprotein cholesterol levels
WO1994000592A1 (en) * 1992-06-26 1994-01-06 Exocell, Inc. Monoclonal antibodies against glycated low density lipoprotein
CA2142007C (en) * 1992-08-11 2007-10-30 Robert Glen Urban Immunomodulatory peptides
KR0185334B1 (ko) 1995-11-02 1999-04-01 김은영 인간 혈장 아포지단백질 비-100에 결합하는 생쥐 항체를 암호하는 씨디엔에이
GB9609702D0 (en) * 1996-05-09 1996-07-10 Royal Free Hosp School Med Anticoagulant peptides
GB9620153D0 (en) * 1996-09-27 1996-11-13 Univ Strathclyde Non-naturally occurring lipoprotein particle
GB9705831D0 (en) * 1997-03-20 1997-05-07 Univ Leicester Oxidised ldl
US6635623B1 (en) * 1997-06-13 2003-10-21 Baylor College Of Medicine Lipoproteins as nucleic acid vectors
US6225070B1 (en) 1997-08-07 2001-05-01 The Regents Of The University Of California Antibodies to oxidation-specific epitopes on lipoprotein and methods for their use in detecting, monitoring and inhibiting the growth of atheroma
US6156315A (en) * 1997-10-10 2000-12-05 The Trustees Of Columbia University In The City Of New York Method for inhibiting the binding of low density lipoprotein to blood vessel matrix
US6309844B1 (en) * 1997-10-15 2001-10-30 Fujirebio Inc. Anti-apo-B-48 monoclonal antibody, hybridoma producing the same, and method for measuring apo-B-48 using the same
WO1999046598A1 (en) * 1998-03-10 1999-09-16 The Regents Of The University Of California Methods and tools for identifying compounds which modulate atherosclerosis by impacting ldl-proteoglycan binding
AU5200699A (en) * 1998-07-13 2000-02-01 University Of Otago Inhibition of lipoprotein formation
IL126447A (en) * 1998-10-04 2004-09-27 Vascular Biogenics Ltd An immune preparation that confers tolerance in oral administration and its use in the prevention and / or treatment of atherosclerosis
MXPA02004244A (es) * 1999-10-26 2002-11-04 Univ California Reactivos y metodos para el diagnostico, la formacion de imagenes y el tratamiento del padecimiento de la ateroesclerosis..
AU2001233114A1 (en) * 2000-02-04 2001-08-14 Aeomica, Inc. Methods and apparatus for predicting, confirming, and displaying functional information derived from genomic sequence
CZ20022971A3 (cs) * 2000-03-03 2003-02-12 Smithkline Beecham Biologicals S. A. Vakcinační prostředek vhodný pro léčbu aterosklerózy
SE0000855D0 (sv) * 2000-03-15 2000-03-15 Karolinska Innovations Ab Antigenic composition useful as a vaccine against atherosclerosis
GB0017641D0 (en) * 2000-07-18 2000-09-06 Medigene Oy Peptides and their use
EP1186299A1 (en) * 2000-09-12 2002-03-13 Universitair Medisch Centrum Utrecht The diagnosis, prevention, and/or succesful treatment of atherosclerosis, infectious diseases, and disturbances in the immune system
AU2002243382A1 (en) * 2000-10-25 2002-06-24 Vincent Agnello Method of inhibiting infection by HCV, other flaviviridae viruses, and any other virus that complexes to low density lipoprotein or to very low density lipoprotein in blood preventing viral entry into a cell
WO2002042426A2 (en) * 2000-11-10 2002-05-30 University Of Utah Research Foundation Carrier system for specific artery wall gene delivery
SE0103754L (sv) * 2001-04-05 2002-10-06 Forskarpatent I Syd Ab Peptider från apolipoprotein B, användning därav immunisering, diagnosmetod eller terapeutisk behandling av ischemiska kardiovaskulära sjukdomar, samt farmaceutisk komposition och vaccin innehållande sådan peptid
US7241861B2 (en) * 2001-05-15 2007-07-10 Japan Immunoresearch Laboratories Co., Ltd. High density lipoprotein-reactive peptides
WO2003007689A2 (en) * 2001-07-20 2003-01-30 Eidgenoessische Technische Hochschule Zurich (Ethz) Compositions and methods for use of bioactive agents derived from sulfated and sulfonated amino acids

Similar Documents

Publication Publication Date Title
JP2009191078A5 (enExample)
JP2010500399A5 (enExample)
RU2003132443A (ru) Иммунотерапия на основе пептидов для лечения атеросклероза и разработка на основе пептидов теста для определения иммунных ответов против окисленного липопротеина низкой плотности
NO20076239L (no) Peptidkonjugatpreparater og fremgangsmater for forebygging og behandling av Alzheimers sykdom
JP2015517489A5 (enExample)
JP2016502551A5 (enExample)
RU2014143531A (ru) Вакцина против PCSK9
JP2013536240A5 (enExample)
JP2012500001A5 (enExample)
PH12016500103A1 (en) Bioconjugates of synthetic apelin polypeptides
JP2012501959A5 (enExample)
JP2025084745A5 (enExample)
JP2010537961A5 (enExample)
CA2729414A1 (en) Vaccine against amyloid folding intermediate
JP2013518052A5 (enExample)
JP2011528897A5 (enExample)
RU2016108139A (ru) Композиция neisseria meningitidis и способ индуцирования иммунного ответа
JP2009520758A5 (enExample)
JP2015529677A5 (enExample)
JP2018532782A5 (enExample)
AR051023A1 (es) Vacunas que contienen antigeno de plasmodium
JP2006523185A5 (enExample)
JP2019507786A5 (enExample)
JP2010501595A5 (enExample)
JP2021524280A (ja) ハウスダストダニアレルギーの処置および予防