JP2009191078A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2009191078A5 JP2009191078A5 JP2009133383A JP2009133383A JP2009191078A5 JP 2009191078 A5 JP2009191078 A5 JP 2009191078A5 JP 2009133383 A JP2009133383 A JP 2009133383A JP 2009133383 A JP2009133383 A JP 2009133383A JP 2009191078 A5 JP2009191078 A5 JP 2009191078A5
- Authority
- JP
- Japan
- Prior art keywords
- peptide
- derivative
- epitope
- heart disease
- ischemic heart
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108090000765 processed proteins & peptides Proteins 0.000 claims 20
- 208000031225 myocardial ischemia Diseases 0.000 claims 7
- 201000001320 Atherosclerosis Diseases 0.000 claims 5
- 241000124008 Mammalia Species 0.000 claims 3
- 208000005764 Peripheral Arterial Disease Diseases 0.000 claims 3
- 208000030831 Peripheral arterial occlusive disease Diseases 0.000 claims 3
- 239000002671 adjuvant Substances 0.000 claims 3
- 208000010125 myocardial infarction Diseases 0.000 claims 3
- 208000023516 stroke disease Diseases 0.000 claims 3
- 150000001299 aldehydes Chemical class 0.000 claims 2
- 208000029078 coronary artery disease Diseases 0.000 claims 2
- 238000002649 immunization Methods 0.000 claims 2
- 230000003053 immunization Effects 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 102000004196 processed proteins & peptides Human genes 0.000 claims 2
- 238000011282 treatment Methods 0.000 claims 2
- 229960005486 vaccine Drugs 0.000 claims 2
- STRVVRPNBAHXRJ-UHFFFAOYSA-N 2-hydroxynon-2-enal Chemical class CCCCCCC=C(O)C=O STRVVRPNBAHXRJ-UHFFFAOYSA-N 0.000 claims 1
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 claims 1
- 229910052802 copper Inorganic materials 0.000 claims 1
- 239000010949 copper Substances 0.000 claims 1
- 238000009109 curative therapy Methods 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 208000019622 heart disease Diseases 0.000 claims 1
- 238000009169 immunotherapy Methods 0.000 claims 1
- 239000002502 liposome Substances 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 230000000069 prophylactic effect Effects 0.000 claims 1
- 238000011321 prophylaxis Methods 0.000 claims 1
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0101232-7 | 2001-04-05 | ||
| SE0101232A SE0101232D0 (sv) | 2001-04-05 | 2001-04-05 | Peptide-based immunization therapy for treatment of atherosclerosis and development of peptide-based elisa for determination of immune responses against oxidized low density liprotein |
| SE0103754-8 | 2001-11-09 | ||
| SE0103754A SE0103754L (sv) | 2001-04-05 | 2001-11-09 | Peptider från apolipoprotein B, användning därav immunisering, diagnosmetod eller terapeutisk behandling av ischemiska kardiovaskulära sjukdomar, samt farmaceutisk komposition och vaccin innehållande sådan peptid |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002578993A Division JP2004529143A (ja) | 2001-04-05 | 2002-04-05 | アテローム性動脈硬化症の治療のためのペプチドに基づいた免疫治療、及び酸化した低密度リポ蛋白質に対する免疫応答の測定のためのペプチドベースのアッセーの開発 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013034312A Division JP5613890B2 (ja) | 2001-04-05 | 2013-02-25 | アテローム性動脈硬化症の治療のためのペプチドに基づいた免疫治療、及び酸化した低密度リポ蛋白質に対する免疫応答の測定のためのペプチドベースのアッセーの開発 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009191078A JP2009191078A (ja) | 2009-08-27 |
| JP2009191078A5 true JP2009191078A5 (enExample) | 2011-06-16 |
| JP5270456B2 JP5270456B2 (ja) | 2013-08-21 |
Family
ID=26655437
Family Applications (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002578993A Withdrawn JP2004529143A (ja) | 2001-04-05 | 2002-04-05 | アテローム性動脈硬化症の治療のためのペプチドに基づいた免疫治療、及び酸化した低密度リポ蛋白質に対する免疫応答の測定のためのペプチドベースのアッセーの開発 |
| JP2008015545A Withdrawn JP2008169215A (ja) | 2001-04-05 | 2008-01-25 | アテローム性動脈硬化症の治療のためのペプチドに基づいた免疫治療、及び酸化した低密度リポ蛋白質に対する免疫応答の測定のためのペプチドベースのアッセーの開発 |
| JP2009133383A Expired - Fee Related JP5270456B2 (ja) | 2001-04-05 | 2009-06-02 | アテローム性動脈硬化症の治療のためのペプチドに基づいた免疫治療、及び酸化した低密度リポ蛋白質に対する免疫応答の測定のためのペプチドベースのアッセーの開発 |
| JP2010239478A Expired - Lifetime JP5300820B2 (ja) | 2001-04-05 | 2010-10-26 | アテローム性動脈硬化症の治療のためのペプチドに基づいた免疫治療、及び酸化した低密度リポ蛋白質に対する免疫応答の測定のためのペプチドベースのアッセーの開発 |
| JP2010239477A Expired - Lifetime JP5300819B2 (ja) | 2001-04-05 | 2010-10-26 | アテローム性動脈硬化症の治療のためのペプチドに基づいた免疫治療、及び酸化した低密度リポ蛋白質に対する免疫応答の測定のためのペプチドベースのアッセーの開発 |
| JP2013034312A Expired - Lifetime JP5613890B2 (ja) | 2001-04-05 | 2013-02-25 | アテローム性動脈硬化症の治療のためのペプチドに基づいた免疫治療、及び酸化した低密度リポ蛋白質に対する免疫応答の測定のためのペプチドベースのアッセーの開発 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002578993A Withdrawn JP2004529143A (ja) | 2001-04-05 | 2002-04-05 | アテローム性動脈硬化症の治療のためのペプチドに基づいた免疫治療、及び酸化した低密度リポ蛋白質に対する免疫応答の測定のためのペプチドベースのアッセーの開発 |
| JP2008015545A Withdrawn JP2008169215A (ja) | 2001-04-05 | 2008-01-25 | アテローム性動脈硬化症の治療のためのペプチドに基づいた免疫治療、及び酸化した低密度リポ蛋白質に対する免疫応答の測定のためのペプチドベースのアッセーの開発 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010239478A Expired - Lifetime JP5300820B2 (ja) | 2001-04-05 | 2010-10-26 | アテローム性動脈硬化症の治療のためのペプチドに基づいた免疫治療、及び酸化した低密度リポ蛋白質に対する免疫応答の測定のためのペプチドベースのアッセーの開発 |
| JP2010239477A Expired - Lifetime JP5300819B2 (ja) | 2001-04-05 | 2010-10-26 | アテローム性動脈硬化症の治療のためのペプチドに基づいた免疫治療、及び酸化した低密度リポ蛋白質に対する免疫応答の測定のためのペプチドベースのアッセーの開発 |
| JP2013034312A Expired - Lifetime JP5613890B2 (ja) | 2001-04-05 | 2013-02-25 | アテローム性動脈硬化症の治療のためのペプチドに基づいた免疫治療、及び酸化した低密度リポ蛋白質に対する免疫応答の測定のためのペプチドベースのアッセーの開発 |
Country Status (18)
| Country | Link |
|---|---|
| EP (42) | EP2147928A3 (enExample) |
| JP (6) | JP2004529143A (enExample) |
| CN (4) | CN103122031B (enExample) |
| AT (2) | ATE510851T1 (enExample) |
| AU (1) | AU2002246484B8 (enExample) |
| BR (1) | BR0208685A (enExample) |
| CA (3) | CA2827167A1 (enExample) |
| CY (1) | CY1108817T1 (enExample) |
| DE (1) | DE60230029D1 (enExample) |
| DK (3) | DK2006301T3 (enExample) |
| EE (2) | EE200700052A (enExample) |
| ES (2) | ES2546293T3 (enExample) |
| IL (4) | IL158285A0 (enExample) |
| PL (4) | PL400308A1 (enExample) |
| PT (1) | PT1383526E (enExample) |
| RU (1) | RU2296582C2 (enExample) |
| SE (1) | SE0103754L (enExample) |
| WO (1) | WO2002080954A1 (enExample) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE0103754L (sv) * | 2001-04-05 | 2002-10-06 | Forskarpatent I Syd Ab | Peptider från apolipoprotein B, användning därav immunisering, diagnosmetod eller terapeutisk behandling av ischemiska kardiovaskulära sjukdomar, samt farmaceutisk komposition och vaccin innehållande sådan peptid |
| US20030105003A1 (en) | 2001-04-05 | 2003-06-05 | Jan Nilsson | Peptide-based immunization therapy for treatment of atherosclerosis and development of peptide-based assay for determination of immune responses against oxidized low density lipoprotein |
| CA2460787A1 (en) | 2001-09-28 | 2003-04-03 | Esperion Therapeutics, Inc. | Prevention and treatment of restenosis by local administration of drug |
| SE0302312D0 (sv) * | 2002-10-04 | 2003-08-27 | Forskarpatent I Syd Ab | Peptide-based passive immunization therapy for treatment of atherosclerosis |
| AU2003267905B2 (en) * | 2002-10-04 | 2009-02-05 | Biolnvent International Ab | Peptide-based passive immunization therapy for treatment of atherosclerosis |
| SE0302422D0 (sv) * | 2003-09-11 | 2003-09-11 | Forskarpatent I Syd Ab | Peptide-based immunization therapy for treatment of atherosclerosis |
| SE0400683D0 (sv) | 2004-03-19 | 2004-03-19 | Forskarpatent I Syd Ab | Use of modified extracellular matrix proteins in diagnosis and treatment of a atherosclerosis |
| JP2007531537A (ja) | 2004-04-06 | 2007-11-08 | セダーズ−シナイ メディカル センター | アポリポタンパク質a−iおよびアポリポタンパク質a−imilanoをコードする組換えアデノ随伴ウイルスベクターによる血管疾患の予防および処置 |
| DE602005023428D1 (de) | 2004-04-15 | 2010-10-21 | Athera Biotechnologies Ab | Verfahren zur Feststellung der Gefahren von ischemischen Herzgefässerkrankungen mit PhosphorylcholinKonjugaten |
| EP1676602A1 (en) * | 2005-01-04 | 2006-07-05 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Continuous administration of epitopes derived from protein present in atherosclerotic plaque for the treatment of atherosclerosis |
| GB0517878D0 (en) | 2005-09-02 | 2005-10-12 | Bioinvent Int Ab | Immunotherapeutic treatment |
| BRPI0720215A2 (pt) * | 2006-12-22 | 2013-12-24 | Abbott Lab | Painel de doença autoimune cardiovascular e métodos de usar o mesmo. |
| WO2008104194A1 (en) * | 2007-02-28 | 2008-09-04 | Bioinvent International Ab | Oxidized ldl and antibodies thereto for the treatment of atheroscleroti c plaques |
| JP5550352B2 (ja) | 2007-03-15 | 2014-07-16 | ノバルティス アーゲー | 有機化合物およびその使用 |
| DK2538222T3 (da) * | 2007-11-05 | 2021-11-15 | Nordic Bioscience As | Biokemiske markører til cvd-risikovurdering |
| US20100041663A1 (en) | 2008-07-18 | 2010-02-18 | Novartis Ag | Organic Compounds as Smo Inhibitors |
| CN102099470B (zh) * | 2008-08-15 | 2014-11-12 | 藤仓化成株式会社 | 用于诊断动脉硬化的多肽标记、用该标记等检测动脉硬化的方法以及用于诊断动脉硬化的试剂盒 |
| JP2013510586A (ja) * | 2009-11-14 | 2013-03-28 | チュウ、カン−ユウ | アテローム性動脈硬化を治療及び/又は予防するための免疫調節方法及びシステム |
| US8506964B2 (en) * | 2010-02-05 | 2013-08-13 | Cardiovax, Llc | Fusion proteins and related compositions, methods and systems for treatment and/or prevention of atherosclerosis |
| US20130142760A1 (en) | 2010-08-18 | 2013-06-06 | Cedars-Sinai Medical Center | Atherosclerosis inhibition via modulation of monocyte-macrophage phenotype using apo a-i milano gene transfer |
| RU2013126626A (ru) | 2010-11-12 | 2014-12-20 | Седарс-Синаи Медикал Сентер | Иммуномодулирующие способы и системы для лечения и/или предотвращения гипертензий |
| EP2637685A1 (en) * | 2010-11-12 | 2013-09-18 | Cedars-Sinai Medical Center | Immunomodulatory methods and systems for treatment and/or prevention of aneurysms |
| CA2817548A1 (en) * | 2010-11-12 | 2012-05-18 | Cedars-Sinai Medical Center | Immunomodulatory compositions, methods and systems comprising immunogenic fragments of apob100 |
| JP6277126B2 (ja) | 2011-08-09 | 2018-02-07 | アセラ・バイオテクノロジーズ・アーベー | ホスホリルコリン(pc)および/またはpcコンジュゲートに結合する抗体 |
| BR112014002929A8 (pt) | 2011-08-09 | 2021-09-28 | Athera Biotechnologies Ab | Novos anticorpos contra fosforilcolina |
| RU2495048C1 (ru) * | 2012-04-18 | 2013-10-10 | Андрей Валентинович Исаев | Пептид, обладающий антиатеросклеротическим действием и композиция для профилактики и лечения атеросклероза сосудов |
| RU2662973C2 (ru) | 2012-11-06 | 2018-07-31 | Лез Опито Юниверситер Де Женев | Пептидомиметики |
| CN103520713B (zh) * | 2013-10-16 | 2015-10-28 | 西北农林科技大学 | 一种ApoB100酵母重组疫苗及其制备方法和应用 |
| CN103860470A (zh) * | 2014-03-05 | 2014-06-18 | 贵州中泰生物科技有限公司 | 一种口服高密度脂蛋白脂质体的制备方法 |
| CN105315364B (zh) * | 2014-06-17 | 2018-09-18 | 广州文瑞生物科技有限公司 | 胶原蛋白vi疫苗预防动脉粥样硬化 |
| US11130798B2 (en) | 2015-05-19 | 2021-09-28 | La Jolla Institute For Allergy And Immunology | Human APOB100 epitopes, methods and uses for modulating inflammatory responses, and treating adverse cardiovascular events, disease and atherosclerosis |
| US10858422B2 (en) | 2016-05-31 | 2020-12-08 | Abcentra, Llc | Methods for treating systemic lupus erythematosus with an anti-apolipoprotein B antibody |
| CN108478817B (zh) * | 2018-03-16 | 2020-10-27 | 北京大学 | 一种动脉粥样硬化检测试剂及其制备方法 |
| CA3101767A1 (en) | 2018-05-29 | 2019-12-05 | Abcentra, Llc | Compositions and methods for treatment of psoriasis |
| CA3129373A1 (en) | 2018-05-29 | 2019-12-05 | Abcentra, Llc | Compositions and methods for treatment of rheumatoid arthritis and accelerated atherosclerosis |
| CN115025210B (zh) * | 2021-03-05 | 2025-09-05 | 香港中文大学 | 减少动脉粥样硬化进展的肽疫苗组合物和药物制剂 |
| CN115025211A (zh) * | 2021-11-02 | 2022-09-09 | 南京理工大学 | 用于动脉粥样硬化治疗的纳米疫苗及其制备方法 |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4970144A (en) | 1984-12-31 | 1990-11-13 | International Genetic Engineering | Peptide fragments of human apolipoprotein, type-specific antibodies and methods of use |
| US5972890A (en) | 1988-05-02 | 1999-10-26 | New England Deaconess Hospital Corporation | Synthetic peptides for arterial imaging |
| WO1993018067A1 (en) * | 1992-03-06 | 1993-09-16 | Abbott Laboratories | Immunocapture assay for direct quantitation of specific lipoprotein cholesterol levels |
| WO1994000592A1 (en) * | 1992-06-26 | 1994-01-06 | Exocell, Inc. | Monoclonal antibodies against glycated low density lipoprotein |
| DE69332485T2 (de) * | 1992-08-11 | 2003-11-13 | The President And Fellows Of Harvard College, Cambridge | Immunmodulierende peptide |
| KR0185334B1 (ko) | 1995-11-02 | 1999-04-01 | 김은영 | 인간 혈장 아포지단백질 비-100에 결합하는 생쥐 항체를 암호하는 씨디엔에이 |
| GB9609702D0 (en) * | 1996-05-09 | 1996-07-10 | Royal Free Hosp School Med | Anticoagulant peptides |
| GB9620153D0 (en) * | 1996-09-27 | 1996-11-13 | Univ Strathclyde | Non-naturally occurring lipoprotein particle |
| GB9705831D0 (en) * | 1997-03-20 | 1997-05-07 | Univ Leicester | Oxidised ldl |
| US6635623B1 (en) * | 1997-06-13 | 2003-10-21 | Baylor College Of Medicine | Lipoproteins as nucleic acid vectors |
| US6225070B1 (en) | 1997-08-07 | 2001-05-01 | The Regents Of The University Of California | Antibodies to oxidation-specific epitopes on lipoprotein and methods for their use in detecting, monitoring and inhibiting the growth of atheroma |
| US6156315A (en) * | 1997-10-10 | 2000-12-05 | The Trustees Of Columbia University In The City Of New York | Method for inhibiting the binding of low density lipoprotein to blood vessel matrix |
| US6309844B1 (en) * | 1997-10-15 | 2001-10-30 | Fujirebio Inc. | Anti-apo-B-48 monoclonal antibody, hybridoma producing the same, and method for measuring apo-B-48 using the same |
| EP1062512A4 (en) * | 1998-03-10 | 2001-12-12 | Univ California | METHODS AND TOOLS USED TO IDENTIFY COMPOUNDS THAT MODULATE ATHEROSCLEROSIS BY ALTERATION OF THE LDL-PROTEOGLYCANE BINDING |
| AU5200699A (en) * | 1998-07-13 | 2000-02-01 | University Of Otago | Inhibition of lipoprotein formation |
| IL126447A (en) * | 1998-10-04 | 2004-09-27 | Vascular Biogenics Ltd | An immune preparation that confers tolerance in oral administration and its use in the prevention and / or treatment of atherosclerosis |
| MXPA02004244A (es) * | 1999-10-26 | 2002-11-04 | Univ California | Reactivos y metodos para el diagnostico, la formacion de imagenes y el tratamiento del padecimiento de la ateroesclerosis.. |
| AU3087801A (en) * | 2000-02-04 | 2001-08-14 | Molecular Dynamics Inc | Human genome-derived single exon nucleic acid probes useful for analysis of geneexpression in human breast and hbl 100 cells |
| US20030165503A1 (en) * | 2000-03-03 | 2003-09-04 | Jean-Charles Fruchart | Vaccine for the treatment of atherosclerosis |
| SE0000855D0 (sv) * | 2000-03-15 | 2000-03-15 | Karolinska Innovations Ab | Antigenic composition useful as a vaccine against atherosclerosis |
| GB0017641D0 (en) * | 2000-07-18 | 2000-09-06 | Medigene Oy | Peptides and their use |
| EP1186299A1 (en) * | 2000-09-12 | 2002-03-13 | Universitair Medisch Centrum Utrecht | The diagnosis, prevention, and/or succesful treatment of atherosclerosis, infectious diseases, and disturbances in the immune system |
| JP2004529080A (ja) * | 2000-10-25 | 2004-09-24 | アグネッロ,ヴィンセント | Hcv、他のフラビウイルス科ウイルス、および血液中で低密度リポタンパク質または超低密度リポタンパク質と複合体を形成するその他のあらゆるウイルスによる感染を細胞中へのウイルス侵入を抑制することによって防止する方法 |
| AU2002241603A1 (en) * | 2000-11-10 | 2002-06-03 | University Of Utah Research Foundation | Carrier system for specific artery wall gene delivery |
| SE0103754L (sv) * | 2001-04-05 | 2002-10-06 | Forskarpatent I Syd Ab | Peptider från apolipoprotein B, användning därav immunisering, diagnosmetod eller terapeutisk behandling av ischemiska kardiovaskulära sjukdomar, samt farmaceutisk komposition och vaccin innehållande sådan peptid |
| RU2003136090A (ru) * | 2001-05-15 | 2005-04-20 | Джэпэн Иммьюнорисерч Лэборэтериз Ко., Лтд (Jp) | Пептид, взаимодействующий с липопротеином высокой плотности |
| EP1469887A4 (en) * | 2001-07-20 | 2006-01-11 | Eidgenoess Tech Hochschule | COMPOSITIONS AND METHODS FOR THE USE OF BIOACTIVE AGENTS DERIVED FROM SULFATE AND SULFONIC ACIDS |
-
2001
- 2001-11-09 SE SE0103754A patent/SE0103754L/xx not_active Application Discontinuation
-
2002
- 2002-04-05 CN CN201210322795.9A patent/CN103122031B/zh not_active Expired - Lifetime
- 2002-04-05 EP EP08158141A patent/EP2147928A3/en not_active Withdrawn
- 2002-04-05 EP EP10180091A patent/EP2305706A1/en not_active Withdrawn
- 2002-04-05 EP EP10180111A patent/EP2289914A1/en not_active Withdrawn
- 2002-04-05 EP EP10180845A patent/EP2289924A1/en not_active Withdrawn
- 2002-04-05 EP EP10180168A patent/EP2295461A1/en not_active Withdrawn
- 2002-04-05 EP EP08167532A patent/EP2147680A3/en not_active Withdrawn
- 2002-04-05 AT AT08151489T patent/ATE510851T1/de not_active IP Right Cessation
- 2002-04-05 EP EP10181167A patent/EP2289925A1/en not_active Withdrawn
- 2002-04-05 EP EP10181196A patent/EP2289928A1/en not_active Withdrawn
- 2002-04-05 BR BR0208685-9A patent/BR0208685A/pt not_active Application Discontinuation
- 2002-04-05 CN CNA2009100095655A patent/CN101486766A/zh active Pending
- 2002-04-05 EP EP10180188A patent/EP2289916A1/en not_active Withdrawn
- 2002-04-05 EP EP10180184A patent/EP2295462A1/en not_active Withdrawn
- 2002-04-05 EP EP10181245A patent/EP2289933A1/en not_active Withdrawn
- 2002-04-05 CA CA2827167A patent/CA2827167A1/en not_active Abandoned
- 2002-04-05 EP EP10181273A patent/EP2289935A1/en not_active Withdrawn
- 2002-04-05 EP EP10180199A patent/EP2289918A1/en not_active Withdrawn
- 2002-04-05 PT PT02714667T patent/PT1383526E/pt unknown
- 2002-04-05 EP EP10180156A patent/EP2295459A1/en not_active Withdrawn
- 2002-04-05 WO PCT/SE2002/000679 patent/WO2002080954A1/en not_active Ceased
- 2002-04-05 IL IL15828502A patent/IL158285A0/xx unknown
- 2002-04-05 DK DK08151489.5T patent/DK2006301T3/da active
- 2002-04-05 EP EP10181253.5A patent/EP2289934B1/en not_active Expired - Lifetime
- 2002-04-05 ES ES10181267.5T patent/ES2546293T3/es not_active Expired - Lifetime
- 2002-04-05 EP EP10181217A patent/EP2289931A1/en not_active Withdrawn
- 2002-04-05 EP EP02714667A patent/EP1383526B1/en not_active Expired - Lifetime
- 2002-04-05 EP EP07119130A patent/EP1918300A3/en not_active Withdrawn
- 2002-04-05 CA CA2443223A patent/CA2443223C/en not_active Expired - Lifetime
- 2002-04-05 PL PL400308A patent/PL400308A1/pl unknown
- 2002-04-05 RU RU2003132443/15A patent/RU2296582C2/ru active
- 2002-04-05 EP EP10180172A patent/EP2289915A1/en not_active Withdrawn
- 2002-04-05 EP EP08151489A patent/EP2006301B1/en not_active Expired - Lifetime
- 2002-04-05 EP EP10181188A patent/EP2289927A1/en not_active Withdrawn
- 2002-04-05 EP EP10180162.9A patent/EP2295460B1/en not_active Expired - Lifetime
- 2002-04-05 DK DK02714667T patent/DK1383526T3/da active
- 2002-04-05 EP EP10180835A patent/EP2289922A1/en not_active Withdrawn
- 2002-04-05 DE DE60230029T patent/DE60230029D1/de not_active Expired - Lifetime
- 2002-04-05 EP EP10181173A patent/EP2289926A1/en not_active Withdrawn
- 2002-04-05 JP JP2002578993A patent/JP2004529143A/ja not_active Withdrawn
- 2002-04-05 AU AU2002246484A patent/AU2002246484B8/en not_active Expired
- 2002-04-05 PL PL02367301A patent/PL367301A1/xx unknown
- 2002-04-05 EP EP08167533A patent/EP2147930A3/en not_active Withdrawn
- 2002-04-05 EP EP10180109A patent/EP2289913A1/en not_active Withdrawn
- 2002-04-05 PL PL385189A patent/PL215401B1/pl unknown
- 2002-04-05 EP EP10180106A patent/EP2289912A1/en not_active Withdrawn
- 2002-04-05 CA CA2606839A patent/CA2606839C/en not_active Expired - Lifetime
- 2002-04-05 EP EP10180823A patent/EP2289919A1/en not_active Withdrawn
- 2002-04-05 EP EP10180193A patent/EP2289917A1/en not_active Withdrawn
- 2002-04-05 EP EP10180828A patent/EP2289921A1/en not_active Withdrawn
- 2002-04-05 EP EP08167531A patent/EP2147929A3/en not_active Ceased
- 2002-04-05 DK DK10181267.5T patent/DK2295464T3/en active
- 2002-04-05 EP EP10180838A patent/EP2289923A1/en not_active Withdrawn
- 2002-04-05 EE EEP200700052A patent/EE200700052A/xx unknown
- 2002-04-05 CN CN028089405A patent/CN1505525B/zh not_active Expired - Fee Related
- 2002-04-05 EP EP10181227A patent/EP2289932A1/en not_active Withdrawn
- 2002-04-05 EP EP10181267.5A patent/EP2295464B1/en not_active Expired - Lifetime
- 2002-04-05 AT AT02714667T patent/ATE415423T1/de active
- 2002-04-05 PL PL391615A patent/PL217858B1/pl unknown
- 2002-04-05 ES ES02714667T patent/ES2317999T3/es not_active Expired - Lifetime
- 2002-04-05 EP EP10180026A patent/EP2295457A1/en not_active Withdrawn
- 2002-04-05 CN CN2007101953989A patent/CN101284874B/zh not_active Expired - Lifetime
- 2002-04-05 EP EP10181213A patent/EP2289930A1/en not_active Withdrawn
- 2002-04-05 EP EP10180115A patent/EP2305707A1/en not_active Withdrawn
- 2002-04-05 EE EEP200300487A patent/EE200300487A/xx unknown
- 2002-04-05 EP EP10180826A patent/EP2289920A1/en not_active Withdrawn
- 2002-04-05 EP EP10180099A patent/EP2295458A1/en not_active Withdrawn
- 2002-04-05 EP EP10181263A patent/EP2295463A1/en not_active Withdrawn
- 2002-04-05 EP EP10181203A patent/EP2289929A1/en not_active Withdrawn
- 2002-04-05 EP EP10180176A patent/EP2305708A1/en not_active Withdrawn
-
2003
- 2003-10-07 IL IL158285A patent/IL158285A/en active IP Right Grant
-
2007
- 2007-12-20 IL IL188286A patent/IL188286A0/en unknown
-
2008
- 2008-01-25 JP JP2008015545A patent/JP2008169215A/ja not_active Withdrawn
- 2008-11-18 IL IL195356A patent/IL195356A0/en unknown
-
2009
- 2009-02-24 CY CY20091100202T patent/CY1108817T1/el unknown
- 2009-06-02 JP JP2009133383A patent/JP5270456B2/ja not_active Expired - Fee Related
-
2010
- 2010-10-26 JP JP2010239478A patent/JP5300820B2/ja not_active Expired - Lifetime
- 2010-10-26 JP JP2010239477A patent/JP5300819B2/ja not_active Expired - Lifetime
-
2013
- 2013-02-25 JP JP2013034312A patent/JP5613890B2/ja not_active Expired - Lifetime
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2009191078A5 (enExample) | ||
| JP2010500399A5 (enExample) | ||
| RU2003132443A (ru) | Иммунотерапия на основе пептидов для лечения атеросклероза и разработка на основе пептидов теста для определения иммунных ответов против окисленного липопротеина низкой плотности | |
| NO20076239L (no) | Peptidkonjugatpreparater og fremgangsmater for forebygging og behandling av Alzheimers sykdom | |
| AR020050A1 (es) | COMPOSICION FARMACEUTICA PARA EL TRATAMIENTO DE LA ENFERMEDAD AMILOIDOGENICA USO DE UN PÉPTIDO ABETA PARA LA PREPARACIoN DE MEDICAMENTOS | |
| JP2015517489A5 (enExample) | ||
| JP2016539946A5 (enExample) | ||
| JP2013536240A5 (enExample) | ||
| JP2012500001A5 (enExample) | ||
| PH12016500103A1 (en) | Bioconjugates of synthetic apelin polypeptides | |
| JP2012501959A5 (enExample) | ||
| JP2010537961A5 (enExample) | ||
| JP2025084745A5 (enExample) | ||
| JP2008539187A5 (enExample) | ||
| CA2729414A1 (en) | Vaccine against amyloid folding intermediate | |
| JP2013518052A5 (enExample) | ||
| JP2015529677A5 (enExample) | ||
| JP2011528897A5 (enExample) | ||
| CN103874504A (zh) | 疫苗 | |
| JP2009520758A5 (enExample) | ||
| JP2019531293A5 (enExample) | ||
| JP2017508006A5 (enExample) | ||
| JP2018529717A5 (enExample) | ||
| JP2018532782A5 (enExample) | ||
| AR051023A1 (es) | Vacunas que contienen antigeno de plasmodium |