JP2008540549A5 - - Google Patents
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- Publication number
- JP2008540549A5 JP2008540549A5 JP2008511295A JP2008511295A JP2008540549A5 JP 2008540549 A5 JP2008540549 A5 JP 2008540549A5 JP 2008511295 A JP2008511295 A JP 2008511295A JP 2008511295 A JP2008511295 A JP 2008511295A JP 2008540549 A5 JP2008540549 A5 JP 2008540549A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- atom
- lower alkyl
- hydrogen atom
- trpv3
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 0 CCNC(CCCCC1)(CCC2=C1N=C(C)*2)N Chemical compound CCNC(CCCCC1)(CCC2=C1N=C(C)*2)N 0.000 description 2
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US67943805P | 2005-05-09 | 2005-05-09 | |
| US67943605P | 2005-05-09 | 2005-05-09 | |
| US70258405P | 2005-07-25 | 2005-07-25 | |
| PCT/US2006/017995 WO2006122156A2 (en) | 2005-05-09 | 2006-05-09 | Compounds for modulating trpv3 function |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013023822A Division JP2013082755A (ja) | 2005-05-09 | 2013-02-08 | Trpv3機能調節用化合物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008540549A JP2008540549A (ja) | 2008-11-20 |
| JP2008540549A5 true JP2008540549A5 (https=) | 2009-06-25 |
Family
ID=36930222
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008511295A Pending JP2008540549A (ja) | 2005-05-09 | 2006-05-09 | Trpv3機能調節用化合物 |
| JP2013023822A Abandoned JP2013082755A (ja) | 2005-05-09 | 2013-02-08 | Trpv3機能調節用化合物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013023822A Abandoned JP2013082755A (ja) | 2005-05-09 | 2013-02-08 | Trpv3機能調節用化合物 |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US7803790B2 (https=) |
| EP (2) | EP2392328A1 (https=) |
| JP (2) | JP2008540549A (https=) |
| CN (1) | CN101233132A (https=) |
| AU (1) | AU2006244074B2 (https=) |
| CA (1) | CA2608194A1 (https=) |
| TW (1) | TWI401254B (https=) |
| WO (1) | WO2006122156A2 (https=) |
Families Citing this family (72)
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| US7893260B2 (en) * | 2005-11-04 | 2011-02-22 | Hydra Biosciences, Inc. | Substituted quinazolin-4-one compounds for antagonizing TRPV3 function |
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| JP5951625B2 (ja) | 2010-11-24 | 2016-07-13 | ザ・トラスティーズ・オブ・コランビア・ユニバーシティー・イン・ザ・シティー・オブ・ニューヨークThe Trustees Of Columbia University In The City Of New York | 加齢性黄斑変性症およびシュタルガルト病の処置のための非レチノイドrbp4アンタゴニスト |
| US20140031341A1 (en) * | 2010-12-22 | 2014-01-30 | Universitat Munster | Modulators and methods for the treatment of rosacea |
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| US9333202B2 (en) | 2012-05-01 | 2016-05-10 | The Trustees Of Columbia University In The City Of New York | Non-retinoid antagonists for treatment of age-related macular degeneration and stargardt disease |
| CN102747128A (zh) * | 2012-05-24 | 2012-10-24 | 北京海威磐石生物医药科技有限公司 | Trpv3通道蛋白在筛选用于皮肤病治疗或皮肤护理的药物中的应用 |
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| WO2014152018A1 (en) | 2013-03-14 | 2014-09-25 | The Trustees Of Columbia University In The City Of New York | Octahydrocyclopentapyrroles, their preparation and use |
| US9938291B2 (en) | 2013-03-14 | 2018-04-10 | The Trustess Of Columbia University In The City Of New York | N-alkyl-2-phenoxyethanamines, their preparation and use |
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| CN110627770A (zh) | 2013-11-18 | 2019-12-31 | 福马疗法公司 | 作为bet溴域抑制剂的四氢喹啉组成物 |
| RU2720237C2 (ru) | 2013-11-18 | 2020-04-28 | Форма Терапеутикс, Инк. | Композиции, содержащие бензопиперазин, в качестве ингибиторов бромодоменов вет |
| SG11201608943VA (en) | 2014-04-30 | 2016-11-29 | Univ Columbia | Substituted 4-phenylpiperidines, their preparaiton and use |
| WO2016028325A1 (en) | 2014-08-22 | 2016-02-25 | Duke University | Trpa1 and trpv4 inhibitors and methods of using the same for organ-specific inflammation and itch |
| TW201702218A (zh) * | 2014-12-12 | 2017-01-16 | 美國杰克森實驗室 | 關於治療癌症、自體免疫疾病及神經退化性疾病之組合物及方法 |
| US11229628B2 (en) | 2015-01-09 | 2022-01-25 | Duke University | TRPA1 and TRPV4 inhibitors and methods of using the same for organ-specific inflammation and itch |
| WO2016121433A1 (ja) * | 2015-01-28 | 2016-08-04 | シャープ株式会社 | 端末装置、基地局装置、通信方法および集積回路 |
| WO2016160938A1 (en) * | 2015-04-02 | 2016-10-06 | Abbvie Inc. | N-(1,3-thiazol-2-yl)pyrimidine-5-carboxamides as trpv3 modulators |
| CN109310683A (zh) | 2016-04-07 | 2019-02-05 | 杜克大学 | 用于消毒和麻醉的trpv4和trpa1的小分子双重抑制剂 |
| CN114748624A (zh) * | 2016-06-13 | 2022-07-15 | 田边三菱制药株式会社 | 用于治疗或预防血管舒缩症状的组合物 |
| WO2018129609A1 (en) * | 2017-01-10 | 2018-07-19 | Owen-Barry Pharmaceuticals Inc. | Anticonvulsant compounds |
| KR20190063746A (ko) * | 2017-11-30 | 2019-06-10 | (주)인핸스드바이오 | p34 단백질 및 NEDD4-1 단백질의 결합 억제제로서의 신규 화합물 및 이의 용도 |
| CN110339360B (zh) * | 2018-04-02 | 2024-04-19 | 苏中药业集团股份有限公司 | 瞬时受体电位阳离子通道trpv3在研制预防或治疗银屑病药物中的应用 |
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| WO2022112352A1 (en) * | 2020-11-24 | 2022-06-02 | Katholieke Universiteit Leuven | Heterocycle derivatives for treating trpm3 mediated disorders |
| US20230391739A1 (en) * | 2020-11-24 | 2023-12-07 | Katholieke Universiteit Leuven | Aryl derivatives for treating trpm3 mediated disorders |
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| CN120202189A (zh) | 2022-09-30 | 2025-06-24 | 巴塞尔大学 | 免疫抑制化合物 |
| CN119930563B (zh) * | 2023-12-20 | 2026-03-17 | 苏中药业集团股份有限公司 | 一种瞬时受体电位阳离子通道trpv3抑制剂及其用途 |
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2006
- 2006-05-09 EP EP11006999A patent/EP2392328A1/en not_active Withdrawn
- 2006-05-09 TW TW095116362A patent/TWI401254B/zh not_active IP Right Cessation
- 2006-05-09 JP JP2008511295A patent/JP2008540549A/ja active Pending
- 2006-05-09 US US11/431,942 patent/US7803790B2/en not_active Expired - Fee Related
- 2006-05-09 AU AU2006244074A patent/AU2006244074B2/en not_active Ceased
- 2006-05-09 CA CA002608194A patent/CA2608194A1/en not_active Abandoned
- 2006-05-09 EP EP06759445A patent/EP1888575A2/en not_active Withdrawn
- 2006-05-09 WO PCT/US2006/017995 patent/WO2006122156A2/en not_active Ceased
- 2006-05-09 CN CNA2006800251060A patent/CN101233132A/zh active Pending
-
2010
- 2010-04-06 US US12/755,118 patent/US20100273777A1/en not_active Abandoned
-
2013
- 2013-02-08 JP JP2013023822A patent/JP2013082755A/ja not_active Abandoned
-
2016
- 2016-02-24 US US15/052,385 patent/US20170020858A1/en not_active Abandoned
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