TWI401254B - 用於調節ｔｒｐｖ３功能之化合物 - Google Patents

用於調節ｔｒｐｖ３功能之化合物 Download PDF

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Publication number
TWI401254B
TWI401254B TW095116362A TW95116362A TWI401254B TW I401254 B TWI401254 B TW I401254B TW 095116362 A TW095116362 A TW 095116362A TW 95116362 A TW95116362 A TW 95116362A TW I401254 B TWI401254 B TW I401254B
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Taiwan
Prior art keywords
group
lower alkyl
sulfonylamino
decylamino
alkoxy
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TW095116362A
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English (en)
Chinese (zh)
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TW200716624A (en
Inventor
Jayhong A Chong
Amy Ripka
Dennis John Underwood
Xiao Guang Zhen
Christopher M Fanger
Magdalene M Moran
Manfred Weigele
William C Lumma
Glenn Larsen
Anu Mahadevan
Peter Meltzer
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Hydra Biosciences Inc
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Publication of TW200716624A publication Critical patent/TW200716624A/zh
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Publication of TWI401254B publication Critical patent/TWI401254B/zh

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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
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  • Veterinary Medicine (AREA)
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  • Animal Behavior & Ethology (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
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  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
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  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Psychology (AREA)
  • Physiology (AREA)
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  • Heart & Thoracic Surgery (AREA)
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  • Hospice & Palliative Care (AREA)
  • Cardiology (AREA)
  • Gastroenterology & Hepatology (AREA)
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TW095116362A 2005-05-09 2006-05-09 用於調節ｔｒｐｖ３功能之化合物 TWI401254B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US67943805P 2005-05-09 2005-05-09
US67943605P 2005-05-09 2005-05-09
US70258405P 2005-07-25 2005-07-25

Publications (2)

Publication Number Publication Date
TW200716624A TW200716624A (en) 2007-05-01
TWI401254B true TWI401254B (zh) 2013-07-11

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US (3) US7803790B2 (https=)
EP (2) EP2392328A1 (https=)
JP (2) JP2008540549A (https=)
CN (1) CN101233132A (https=)
AU (1) AU2006244074B2 (https=)
CA (1) CA2608194A1 (https=)
TW (1) TWI401254B (https=)
WO (1) WO2006122156A2 (https=)

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US8916550B2 (en) * 2005-05-09 2014-12-23 Hydra Biosciences, Inc. Compounds for modulating TRPV3 function
EP2392328A1 (en) * 2005-05-09 2011-12-07 Hydra Biosciences, Inc. Compounds for modulating TRPV3 Function
US7893260B2 (en) * 2005-11-04 2011-02-22 Hydra Biosciences, Inc. Substituted quinazolin-4-one compounds for antagonizing TRPV3 function
DE602006015700D1 (de) 2005-11-21 2010-09-02 Anadys Pharmaceuticals Inc Neues verfahren zur herstellung von 5-amino-3h-thiazoloä4,5-düpyrimidin-2-on
WO2007092610A2 (en) 2006-02-07 2007-08-16 Tivamed, Inc. Vaginal remodeling device and methods
CN101096363B (zh) * 2006-06-27 2011-05-11 中国人民解放军军事医学科学院毒物药物研究所 2,4,5-三取代噻唑类化合物、其制备方法、药物组合物及其制药用途
US8481161B2 (en) * 2006-06-28 2013-07-09 Samsung Electronics Co., Ltd. Functionalized metal nanoparticle and method for formation of conductive pattern using the same
US7998980B2 (en) 2006-09-15 2011-08-16 Hydra Biosciences, Inc. Compounds for modulating TRPV3 function
EP2120557A4 (en) * 2006-12-08 2010-02-10 Roskamp Res Llc POLYHYDROQUINOLINE COMPOUNDS AND DIHYDROPYRIDINE COMPOUNDS FOR INHIBITING BETA-AMYLOID PRODUCTION
WO2008140750A1 (en) * 2007-05-10 2008-11-20 Hydra Biosciences Inc. Compounds for modulating trpv3 function
WO2009006580A1 (en) * 2007-07-05 2009-01-08 Cv Therapeutics, Inc. Optionally condensed dihydropyridine, dihydropyrimidine and dihydropyrane derivatives acting as late sodium channel blockers
US20090012103A1 (en) 2007-07-05 2009-01-08 Matthew Abelman Substituted heterocyclic compounds
WO2009102864A1 (en) 2008-02-12 2009-08-20 Stanford University Hedgehog pathway antagonists and methods of use
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