JP2008530245A - 尿路病原性菌株由来の抗原 - Google Patents
尿路病原性菌株由来の抗原 Download PDFInfo
- Publication number
- JP2008530245A JP2008530245A JP2007556382A JP2007556382A JP2008530245A JP 2008530245 A JP2008530245 A JP 2008530245A JP 2007556382 A JP2007556382 A JP 2007556382A JP 2007556382 A JP2007556382 A JP 2007556382A JP 2008530245 A JP2008530245 A JP 2008530245A
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- JP
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- Prior art keywords
- amino acid
- acid sequence
- sequence
- present
- polypeptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
- 239000000427 antigen Substances 0.000 title 1
- 102000036639 antigens Human genes 0.000 title 1
- 108091007433 antigens Proteins 0.000 title 1
- 239000000203 mixture Substances 0.000 claims abstract 7
- 230000002163 immunogen Effects 0.000 claims abstract 6
- 230000028993 immune response Effects 0.000 claims abstract 5
- 239000008194 pharmaceutical composition Substances 0.000 claims abstract 4
- 230000002708 enhancing effect Effects 0.000 claims abstract 3
- 238000000034 method Methods 0.000 claims abstract 3
- 208000015181 infectious disease Diseases 0.000 claims abstract 2
- 230000001681 protective effect Effects 0.000 claims abstract 2
- 125000003275 alpha amino acid group Chemical group 0.000 claims 23
- 229920001184 polypeptide Polymers 0.000 claims 8
- 102000004196 processed proteins & peptides Human genes 0.000 claims 8
- 108090000765 processed proteins & peptides Proteins 0.000 claims 8
- 239000012634 fragment Substances 0.000 claims 7
- 150000001413 amino acids Chemical class 0.000 claims 6
- 210000003719 b-lymphocyte Anatomy 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 239000003937 drug carrier Substances 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000012528 membrane Substances 0.000 claims 1
- 239000012646 vaccine adjuvant Substances 0.000 claims 1
- 229940124931 vaccine adjuvant Drugs 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 abstract 3
- 230000001717 pathogenic effect Effects 0.000 abstract 2
- 241000588724 Escherichia coli Species 0.000 abstract 1
- 230000001413 cellular effect Effects 0.000 abstract 1
- 210000000987 immune system Anatomy 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
- C07K14/245—Escherichia (G)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Materials For Photolithography (AREA)
- Developing Agents For Electrophotography (AREA)
- Medicinal Preparation (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US65463205P | 2005-02-18 | 2005-02-18 | |
| PCT/US2006/005912 WO2006091517A2 (en) | 2005-02-18 | 2006-02-17 | Immunogens from uropathogenic escherichia coli |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012057239A Division JP2012111782A (ja) | 2005-02-18 | 2012-03-14 | 尿路病原性菌株由来の抗原 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008530245A true JP2008530245A (ja) | 2008-08-07 |
| JP2008530245A5 JP2008530245A5 (OSRAM) | 2009-04-02 |
Family
ID=36927922
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007556382A Pending JP2008530245A (ja) | 2005-02-18 | 2006-02-17 | 尿路病原性菌株由来の抗原 |
| JP2012057239A Pending JP2012111782A (ja) | 2005-02-18 | 2012-03-14 | 尿路病原性菌株由来の抗原 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012057239A Pending JP2012111782A (ja) | 2005-02-18 | 2012-03-14 | 尿路病原性菌株由来の抗原 |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US8062644B2 (OSRAM) |
| EP (2) | EP2298795A1 (OSRAM) |
| JP (2) | JP2008530245A (OSRAM) |
| CN (3) | CN102675432A (OSRAM) |
| AT (1) | ATE552267T1 (OSRAM) |
| AU (1) | AU2006216844B2 (OSRAM) |
| CA (1) | CA2598488A1 (OSRAM) |
| DK (1) | DK1858919T3 (OSRAM) |
| ES (1) | ES2385045T3 (OSRAM) |
| IL (1) | IL185358A0 (OSRAM) |
| MX (1) | MX291624B (OSRAM) |
| NZ (4) | NZ560929A (OSRAM) |
| SG (1) | SG164344A1 (OSRAM) |
| WO (1) | WO2006091517A2 (OSRAM) |
| ZA (2) | ZA200707808B (OSRAM) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2013516401A (ja) * | 2009-12-30 | 2013-05-13 | ノバルティス アーゲー | E.coliキャリアタンパク質に結合体化した多糖免疫原 |
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| US7082569B2 (en) | 2001-01-17 | 2006-07-25 | Outlooksoft Corporation | Systems and methods providing dynamic spreadsheet functionality |
| MX2007008723A (es) | 2005-01-21 | 2007-09-12 | Epitopix Llc | Polipeptidos de yersinia spp y metodos de uso. |
| EP2298795A1 (en) | 2005-02-18 | 2011-03-23 | Novartis Vaccines and Diagnostics, Inc. | Immunogens from uropathogenic escherichia coli |
| WO2007128838A1 (en) * | 2006-05-10 | 2007-11-15 | Institut National De La Recherche Agronomique | Use of cells containing a specific dna molecule as cytopathic agents to inhibit the proliferation of cells |
| JP2010500399A (ja) | 2006-08-16 | 2010-01-07 | ノバルティス アーゲー | 尿路病原性大腸菌由来の免疫原 |
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| CN101918028B (zh) | 2007-09-18 | 2015-01-07 | 莱戈赛特医药股份有限公司 | 赋予针对诺如病毒的保护性免疫应答的疫苗 |
| EP2271355A2 (en) * | 2008-02-27 | 2011-01-12 | Technische Universität München | Use of prokaryotic tir-domain containing proteins as therapeutic and diagnostic agents |
| JP5852883B2 (ja) | 2008-08-08 | 2016-02-03 | タケダ ワクチン,インコーポレイテッド | 交差反応性の増強のための複合カプシドアミノ酸配列を含むウイルス様粒子 |
| JP2012502972A (ja) | 2008-09-18 | 2012-02-02 | ノバルティス アーゲー | ワクチンアジュバントの組み合わせ |
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| EP2443250B8 (en) | 2009-06-16 | 2016-09-21 | GlaxoSmithKline Biologicals SA | High-throughput complement-mediated antibody-dependent and opsonic bactericidal assays |
| MX2012000395A (es) | 2009-07-07 | 2012-02-28 | Novartis Ag | Inmunogenos conservados de escherichia coli. |
| US8871214B2 (en) | 2009-07-16 | 2014-10-28 | Novartis Ag | Detoxified Escherichia coli immunogens |
| US8858958B2 (en) | 2009-08-27 | 2014-10-14 | Novartis Ag | Adjuvant comprising aluminum, oligonucleotide and polycation |
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| WO2011116262A2 (en) * | 2010-03-19 | 2011-09-22 | The Regents Of The University Of Michigan | Compositions and methods for diagnosing and treating urinary tract infections |
| PL3243526T3 (pl) | 2010-07-06 | 2020-05-18 | Glaxosmithkline Biologicals S.A. | Dostarczanie rna w celu wyzwolenia wielu szlaków immunologicznych |
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| WO2012117377A1 (en) | 2011-03-02 | 2012-09-07 | Novartis Ag | Combination vaccines with lower doses of antigen and/or adjuvant |
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