JP2008526975A5 - - Google Patents
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- JP2008526975A5 JP2008526975A5 JP2007551363A JP2007551363A JP2008526975A5 JP 2008526975 A5 JP2008526975 A5 JP 2008526975A5 JP 2007551363 A JP2007551363 A JP 2007551363A JP 2007551363 A JP2007551363 A JP 2007551363A JP 2008526975 A5 JP2008526975 A5 JP 2008526975A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- alkoxy
- formula
- compound
- cycloalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
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- 238000000034 method Methods 0.000 claims 51
- 125000000217 alkyl group Chemical group 0.000 claims 42
- -1 C 1 to 4 alkylureyl Chemical group 0.000 claims 35
- 125000004414 alkyl thio group Chemical group 0.000 claims 34
- 125000003545 alkoxy group Chemical group 0.000 claims 30
- 150000001875 compounds Chemical class 0.000 claims 30
- 229910052736 halogen Inorganic materials 0.000 claims 26
- 125000001188 haloalkyl group Chemical group 0.000 claims 24
- 150000002367 halogens Chemical class 0.000 claims 23
- 125000004093 cyano group Chemical group *C#N 0.000 claims 22
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 22
- SNOOUWRIMMFWNE-UHFFFAOYSA-M sodium;6-[(3,4,5-trimethoxybenzoyl)amino]hexanoate Chemical compound [Na+].COC1=CC(C(=O)NCCCCCC([O-])=O)=CC(OC)=C1OC SNOOUWRIMMFWNE-UHFFFAOYSA-M 0.000 claims 22
- 125000003282 alkyl amino group Chemical group 0.000 claims 20
- 125000004438 haloalkoxy group Chemical group 0.000 claims 20
- 125000001072 heteroaryl group Chemical group 0.000 claims 20
- 125000002252 acyl group Chemical group 0.000 claims 18
- 125000004644 alkyl sulfinyl group Chemical group 0.000 claims 18
- 125000004390 alkyl sulfonyl group Chemical group 0.000 claims 18
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 18
- 125000000753 cycloalkyl group Chemical group 0.000 claims 18
- 125000004663 dialkyl amino group Chemical group 0.000 claims 18
- 150000003857 carboxamides Chemical class 0.000 claims 17
- 125000004423 acyloxy group Chemical group 0.000 claims 16
- 125000005431 alkyl carboxamide group Chemical group 0.000 claims 16
- 125000005422 alkyl sulfonamido group Chemical group 0.000 claims 16
- 125000005432 dialkylcarboxamide group Chemical group 0.000 claims 16
- 125000004441 haloalkylsulfonyl group Chemical group 0.000 claims 16
- 125000004995 haloalkylthio group Chemical group 0.000 claims 16
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims 16
- 125000000882 C2-C6 alkenyl group Chemical group 0.000 claims 14
- 125000000623 heterocyclic group Chemical group 0.000 claims 14
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 14
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 14
- 125000000304 alkynyl group Chemical group 0.000 claims 12
- 125000004440 haloalkylsulfinyl group Chemical group 0.000 claims 12
- 125000001424 substituent group Chemical group 0.000 claims 12
- 125000006272 (C3-C7) cycloalkyl group Chemical group 0.000 claims 9
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 claims 9
- 125000003601 C2-C6 alkynyl group Chemical group 0.000 claims 6
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical group CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 claims 6
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 claims 6
- 125000004391 aryl sulfonyl group Chemical group 0.000 claims 6
- 125000003739 carbamimidoyl group Chemical group C(N)(=N)* 0.000 claims 6
- 125000000000 cycloalkoxy group Chemical group 0.000 claims 6
- 125000005363 dialkylsulfonamide group Chemical group 0.000 claims 6
- 125000000951 phenoxy group Chemical group [H]C1=C([H])C([H])=C(O*)C([H])=C1[H] 0.000 claims 6
- 230000002140 halogenating effect Effects 0.000 claims 5
- 125000005420 sulfonamido group Chemical group S(=O)(=O)(N*)* 0.000 claims 5
- LSNNMFCWUKXFEE-UHFFFAOYSA-M Bisulfite Chemical compound OS([O-])=O LSNNMFCWUKXFEE-UHFFFAOYSA-M 0.000 claims 4
- XYFCBTPGUUZFHI-UHFFFAOYSA-N Phosphine Natural products P XYFCBTPGUUZFHI-UHFFFAOYSA-N 0.000 claims 4
- WYURNTSHIVDZCO-UHFFFAOYSA-N Tetrahydrofuran Chemical compound C1CCOC1 WYURNTSHIVDZCO-UHFFFAOYSA-N 0.000 claims 4
- 125000003342 alkenyl group Chemical group 0.000 claims 4
- 125000004422 alkyl sulphonamide group Chemical group 0.000 claims 4
- 239000003153 chemical reaction reagent Substances 0.000 claims 4
- 125000005223 heteroarylcarbonyl group Chemical group 0.000 claims 4
- 239000002904 solvent Substances 0.000 claims 4
- 125000003396 thiol group Chemical class [H]S* 0.000 claims 4
- WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 claims 3
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 claims 3
- 239000003054 catalyst Substances 0.000 claims 3
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 claims 3
- 150000003003 phosphines Chemical class 0.000 claims 3
- 229910000073 phosphorus hydride Inorganic materials 0.000 claims 3
- 125000006583 (C1-C3) haloalkyl group Chemical group 0.000 claims 2
- 125000004765 (C1-C4) haloalkyl group Chemical group 0.000 claims 2
- 125000004771 (C1-C4) haloalkylsulfinyl group Chemical group 0.000 claims 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 2
- SJRJJKPEHAURKC-UHFFFAOYSA-N N-Methylmorpholine Chemical group CN1CCOCC1 SJRJJKPEHAURKC-UHFFFAOYSA-N 0.000 claims 2
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 claims 2
- 125000004429 atom Chemical group 0.000 claims 2
- 125000000392 cycloalkenyl group Chemical group 0.000 claims 2
- 125000005843 halogen group Chemical group 0.000 claims 2
- 125000004170 methylsulfonyl group Chemical group [H]C([H])([H])S(*)(=O)=O 0.000 claims 2
- 125000002467 phosphate group Chemical group [H]OP(=O)(O[H])O[*] 0.000 claims 2
- MFRIHAYPQRLWNB-UHFFFAOYSA-N sodium tert-butoxide Chemical group [Na+].CC(C)(C)[O-] MFRIHAYPQRLWNB-UHFFFAOYSA-N 0.000 claims 2
- 150000003460 sulfonic acids Chemical group 0.000 claims 2
- 150000003512 tertiary amines Chemical class 0.000 claims 2
- RIOQSEWOXXDEQQ-UHFFFAOYSA-N triphenylphosphine Chemical group C1=CC=CC=C1P(C=1C=CC=CC=1)C1=CC=CC=C1 RIOQSEWOXXDEQQ-UHFFFAOYSA-N 0.000 claims 2
- XTFIVUDBNACUBN-UHFFFAOYSA-N 1,3,5-trinitro-1,3,5-triazinane Chemical compound [O-][N+](=O)N1CN([N+]([O-])=O)CN([N+]([O-])=O)C1 XTFIVUDBNACUBN-UHFFFAOYSA-N 0.000 claims 1
- AVFZOVWCLRSYKC-UHFFFAOYSA-N 1-methylpyrrolidine Chemical compound CN1CCCC1 AVFZOVWCLRSYKC-UHFFFAOYSA-N 0.000 claims 1
- FXHOOIRPVKKKFG-UHFFFAOYSA-N N,N-Dimethylacetamide Chemical compound CN(C)C(C)=O FXHOOIRPVKKKFG-UHFFFAOYSA-N 0.000 claims 1
- AHVYPIQETPWLSZ-UHFFFAOYSA-N N-methyl-pyrrolidine Natural products CN1CC=CC1 AHVYPIQETPWLSZ-UHFFFAOYSA-N 0.000 claims 1
- DKGAVHZHDRPRBM-UHFFFAOYSA-N Tert-Butanol Chemical class CC(C)(C)O DKGAVHZHDRPRBM-UHFFFAOYSA-N 0.000 claims 1
- 239000003125 aqueous solvent Substances 0.000 claims 1
- 125000005518 carboxamido group Chemical group 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 239000012320 chlorinating reagent Substances 0.000 claims 1
- HHFAWKCIHAUFRX-UHFFFAOYSA-N ethoxide Chemical compound CC[O-] HHFAWKCIHAUFRX-UHFFFAOYSA-N 0.000 claims 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims 1
- ZXEKIIBDNHEJCQ-UHFFFAOYSA-N isobutanol Chemical compound CC(C)CO ZXEKIIBDNHEJCQ-UHFFFAOYSA-N 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- NBTOZLQBSIZIKS-UHFFFAOYSA-N methoxide Chemical group [O-]C NBTOZLQBSIZIKS-UHFFFAOYSA-N 0.000 claims 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 1
- RLOWWWKZYUNIDI-UHFFFAOYSA-N phosphinic chloride Chemical group ClP=O RLOWWWKZYUNIDI-UHFFFAOYSA-N 0.000 claims 1
- IKNCGYCHMGNBCP-UHFFFAOYSA-N propan-1-olate Chemical compound CCC[O-] IKNCGYCHMGNBCP-UHFFFAOYSA-N 0.000 claims 1
- OGHBATFHNDZKSO-UHFFFAOYSA-N propan-2-olate Chemical compound CC(C)[O-] OGHBATFHNDZKSO-UHFFFAOYSA-N 0.000 claims 1
- FVSKHRXBFJPNKK-UHFFFAOYSA-N propionitrile Chemical compound CCC#N FVSKHRXBFJPNKK-UHFFFAOYSA-N 0.000 claims 1
- 229940124530 sulfonamide Drugs 0.000 claims 1
- 150000003456 sulfonamides Chemical class 0.000 claims 1
- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 claims 1
- LGQXXHMEBUOXRP-UHFFFAOYSA-N tributyl borate Chemical compound CCCCOB(OCCCC)OCCCC LGQXXHMEBUOXRP-UHFFFAOYSA-N 0.000 claims 1
- 0 *OC(N=NC(O*=C)=O)=O Chemical compound *OC(N=NC(O*=C)=O)=O 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US64371205P | 2005-01-13 | 2005-01-13 | |
| PCT/US2006/001020 WO2006076455A2 (en) | 2005-01-13 | 2006-01-12 | Processes for preparing pyrazolo[3,4-d]pyrimidine ethers |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008526975A JP2008526975A (ja) | 2008-07-24 |
| JP2008526975A5 true JP2008526975A5 (enExample) | 2009-02-19 |
Family
ID=36463499
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007551363A Withdrawn JP2008526975A (ja) | 2005-01-13 | 2006-01-12 | ピラゾロ[3,4−d]ピリミジンエーテルを調製するための方法 |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US7425630B2 (enExample) |
| EP (1) | EP1838713A2 (enExample) |
| JP (1) | JP2008526975A (enExample) |
| KR (1) | KR20070114126A (enExample) |
| CN (1) | CN101142216A (enExample) |
| AR (1) | AR052557A1 (enExample) |
| AU (1) | AU2006204940A1 (enExample) |
| BR (1) | BRPI0606115A2 (enExample) |
| CA (1) | CA2593345A1 (enExample) |
| CR (1) | CR9224A (enExample) |
| DO (1) | DOP2006000009A (enExample) |
| EA (1) | EA013968B1 (enExample) |
| GT (1) | GT200600011A (enExample) |
| HN (1) | HN2006001493A (enExample) |
| IL (1) | IL184365A0 (enExample) |
| MX (1) | MX2007008381A (enExample) |
| NO (1) | NO20074052L (enExample) |
| PA (1) | PA8659701A1 (enExample) |
| PE (1) | PE20061118A1 (enExample) |
| TW (1) | TW200637865A (enExample) |
| WO (1) | WO2006076455A2 (enExample) |
| ZA (1) | ZA200705279B (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10238722A1 (de) | 2002-08-23 | 2004-03-11 | Bayer Ag | Selektive Phosphodiesterase 9A-Inhibitoren als Arzneimittel zur Verbesserung kognitiver Prozesse |
| HRP20050696B1 (en) | 2003-01-14 | 2008-10-31 | Arena Pharmaceuticals Inc. | 1,2,3-trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prpphylaxis and treatment of disorders related thereto such as diabetes and hyperglycemia |
| US7132426B2 (en) * | 2003-07-14 | 2006-11-07 | Arena Pharmaceuticals, Inc. | Fused-aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto |
| US7923465B2 (en) * | 2005-06-02 | 2011-04-12 | Glenmark Pharmaceuticals S.A. | Cannabinoid receptor ligands, pharmaceutical compositions containing them, and process for their preparation |
| PE20091211A1 (es) | 2007-11-30 | 2009-09-14 | Boehringer Ingelheim Int | Derivados de pirazolopirimidina como moduladores de pde9a |
| UA105362C2 (en) | 2008-04-02 | 2014-05-12 | Бьорингер Ингельхайм Интернациональ Гмбх | 1-heterocyclyl-1, 5-dihydro-pyrazolo [3, 4-d] pyrimidin-4-one derivatives and their use as pde9a modulators |
| WO2010009195A1 (en) * | 2008-07-16 | 2010-01-21 | Schering Corporation | Bicyclic heterocycle derivatives and use thereof as gpr119 modulators |
| CA2736304A1 (en) | 2008-09-08 | 2010-03-11 | Boehringer Ingelheim International Gmbh | Pyrazolopyrimidines and their use for the treatment of cns disorders |
| GEP20146098B (en) | 2009-03-31 | 2014-05-27 | Boehringer Ingelheim Int | 1-heterocyclyl-1, 5-dihydro-pyrazolo [3, 4-d] pyrimidin-4-one derivatives and their usage as pde9a modulators |
| US20100285145A1 (en) * | 2009-05-08 | 2010-11-11 | Pfizer Inc | Gpr 119 modulators |
| JP2012528847A (ja) * | 2009-06-05 | 2012-11-15 | ファイザー・インク | Gpr119調節因子としてのl−(ピペリジン−4−イル)−ピラゾール誘導体 |
| SG182610A1 (en) | 2010-01-27 | 2012-08-30 | Arena Pharm Inc | Processes for the preparation of (r)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid and salts thereof |
| MX344770B (es) | 2010-08-12 | 2017-01-06 | Boehringer Ingelheim Int Gmbh * | Derivados de 6-cicloalquil-1,5-dihidro-pirazolo (3,4-d) pirimidin-4-onas y su uso como inhibidores de pde9a. |
| MX2013003184A (es) | 2010-09-22 | 2013-06-07 | Arena Pharm Inc | Moduladores del receptor gpr119 y el tratamiento de transtornos relacionados con el mismo. |
| US8809345B2 (en) | 2011-02-15 | 2014-08-19 | Boehringer Ingelheim International Gmbh | 6-cycloalkyl-pyrazolopyrimidinones for the treatment of CNS disorders |
| AU2012267556B9 (en) | 2011-06-09 | 2017-05-11 | Rhizen Pharmaceuticals Sa | Novel compounds as modulators of GPR-119 |
| JP6567276B2 (ja) * | 2014-05-13 | 2019-08-28 | ソニーセミコンダクタソリューションズ株式会社 | 固体撮像素子、および電子機器 |
| HK1243936A1 (zh) * | 2014-12-06 | 2018-07-27 | Intra-Cellular Therapies, Inc. | 有机化合物 |
| US11007175B2 (en) | 2015-01-06 | 2021-05-18 | Arena Pharmaceuticals, Inc. | Methods of treating conditions related to the S1P1 receptor |
| BR112017027656B1 (pt) | 2015-06-22 | 2023-12-05 | Arena Pharmaceuticals, Inc. | Hábito cristalino de placa livre de sal de l-arginina de ácido (r)-2-(7-(4- ciclopentil-3-(trifluorometil)benzilóxi)- 1,2,3,4-tetra-hidrociclo-penta[b]indol-3- il)acético, composição farmacêutica que o compreende, seus usos e método de preparação do mesmo |
| CA3053418A1 (en) | 2017-02-16 | 2018-08-23 | Arena Pharmaceuticals, Inc. | Compounds and methods for treatment of primary biliary cholangitis |
| JP2019122134A (ja) | 2018-01-04 | 2019-07-22 | Ntn株式会社 | スイッチング電源の力率改善用pwm制御装置 |
| BR112020024762A2 (pt) | 2018-06-06 | 2021-03-23 | Arena Pharmaceuticals, Inc. | métodos de tratamento de condições relacionadas ao receptor s1p1 |
| IL308071A (en) * | 2021-06-23 | 2023-12-01 | Hoffmann La Roche | Process for preparing NLRP3 inhibitors |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0050671B1 (en) | 1980-04-28 | 1985-03-20 | Teijin Limited | Thiazolo(3,2-a)pyrimidine derivatives, process for preparing same, and drug containing same |
| EP0053678A1 (de) * | 1980-12-05 | 1982-06-16 | BASF Aktiengesellschaft | 5-Amino-1-phenyl-4-cyanpyrazole, diese enthaltende herbizide Mittel, Verfahren zu ihrer Herstellung und ihre Anwendung als Herbizide |
| US4612376A (en) | 1983-03-25 | 1986-09-16 | Fujisawa Pharmaceutical Co., Ltd. | Substituted-3,4-dihydro-4-(2,4,6-trimethoxyphenylimino)-2(1H)-pyrimidones useful as cardiotonic, antihypertensive, cerebrovascular vasodilator and anti-platelet agent |
| GB9114760D0 (en) | 1991-07-09 | 1991-08-28 | Pfizer Ltd | Therapeutic agents |
| JP4022271B2 (ja) * | 1995-10-31 | 2007-12-12 | 富士フイルム株式会社 | ピラゾリルアゾフエノール色素 |
| US6921763B2 (en) * | 1999-09-17 | 2005-07-26 | Abbott Laboratories | Pyrazolopyrimidines as therapeutic agents |
| PT1212327E (pt) * | 1999-09-17 | 2004-01-30 | Abbott Gmbh & Co Kg | Pirazolopirimidinas como agentes terapeuticos |
| DE10219435A1 (de) * | 2002-05-02 | 2003-11-13 | Bayer Cropscience Ag | Substituierte Pyrazolo-pyrimidin-4-one |
| AU2003261204A1 (en) * | 2002-07-23 | 2004-02-09 | Smithkline Beecham Corporation | Pyrazolopyrimidines as kinase inhibitors |
| US7132426B2 (en) * | 2003-07-14 | 2006-11-07 | Arena Pharmaceuticals, Inc. | Fused-aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto |
| GB0425035D0 (en) * | 2004-11-12 | 2004-12-15 | Novartis Ag | Organic compounds |
-
2006
- 2006-01-05 DO DO2006000009A patent/DOP2006000009A/es unknown
- 2006-01-09 TW TW095100806A patent/TW200637865A/zh unknown
- 2006-01-10 PE PE2006000054A patent/PE20061118A1/es not_active Application Discontinuation
- 2006-01-11 GT GT200600011A patent/GT200600011A/es unknown
- 2006-01-12 US US11/331,372 patent/US7425630B2/en not_active Expired - Fee Related
- 2006-01-12 JP JP2007551363A patent/JP2008526975A/ja not_active Withdrawn
- 2006-01-12 AU AU2006204940A patent/AU2006204940A1/en not_active Withdrawn
- 2006-01-12 HN HN2006001493A patent/HN2006001493A/es unknown
- 2006-01-12 KR KR1020077018365A patent/KR20070114126A/ko not_active Withdrawn
- 2006-01-12 WO PCT/US2006/001020 patent/WO2006076455A2/en not_active Ceased
- 2006-01-12 PA PA20068659701A patent/PA8659701A1/es unknown
- 2006-01-12 CN CNA2006800064543A patent/CN101142216A/zh not_active Withdrawn
- 2006-01-12 EA EA200701500A patent/EA013968B1/ru not_active IP Right Cessation
- 2006-01-12 BR BRPI0606115-0A patent/BRPI0606115A2/pt not_active IP Right Cessation
- 2006-01-12 MX MX2007008381A patent/MX2007008381A/es active IP Right Grant
- 2006-01-12 EP EP06718131A patent/EP1838713A2/en not_active Withdrawn
- 2006-01-12 AR ARP060100122A patent/AR052557A1/es not_active Application Discontinuation
- 2006-01-12 CA CA002593345A patent/CA2593345A1/en not_active Withdrawn
-
2007
- 2007-07-02 IL IL184365A patent/IL184365A0/en unknown
- 2007-07-03 CR CR9224A patent/CR9224A/es unknown
- 2007-07-06 ZA ZA200705279A patent/ZA200705279B/xx unknown
- 2007-08-06 NO NO20074052A patent/NO20074052L/no not_active Application Discontinuation
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