JP2008526869A5 - - Google Patents

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Publication number
JP2008526869A5
JP2008526869A5 JP2007550462A JP2007550462A JP2008526869A5 JP 2008526869 A5 JP2008526869 A5 JP 2008526869A5 JP 2007550462 A JP2007550462 A JP 2007550462A JP 2007550462 A JP2007550462 A JP 2007550462A JP 2008526869 A5 JP2008526869 A5 JP 2008526869A5
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JP
Japan
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optionally substituted
heterocyclyl
aryl
alkyl
heteroaryl
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JP2007550462A
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English (en)
Japanese (ja)
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JP5123668B2 (ja
JP2008526869A (ja
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Priority claimed from PCT/US2006/000319 external-priority patent/WO2006076202A1/en
Publication of JP2008526869A publication Critical patent/JP2008526869A/ja
Publication of JP2008526869A5 publication Critical patent/JP2008526869A5/ja
Application granted granted Critical
Publication of JP5123668B2 publication Critical patent/JP5123668B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP2007550462A 2005-01-10 2006-01-06 医薬品としての複素環カルボキサミド化合物 Expired - Fee Related JP5123668B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US64283905P 2005-01-10 2005-01-10
US60/642,839 2005-01-10
PCT/US2006/000319 WO2006076202A1 (en) 2005-01-10 2006-01-06 Heterocyclic carboxamide compounds as steroid nuclear receptors ligands

Publications (3)

Publication Number Publication Date
JP2008526869A JP2008526869A (ja) 2008-07-24
JP2008526869A5 true JP2008526869A5 (enExample) 2009-03-19
JP5123668B2 JP5123668B2 (ja) 2013-01-23

Family

ID=36178222

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007550462A Expired - Fee Related JP5123668B2 (ja) 2005-01-10 2006-01-06 医薬品としての複素環カルボキサミド化合物

Country Status (6)

Country Link
US (1) US20110144128A1 (enExample)
EP (1) EP1844020B1 (enExample)
JP (1) JP5123668B2 (enExample)
AU (1) AU2006205220B2 (enExample)
CA (1) CA2593156C (enExample)
WO (1) WO2006076202A1 (enExample)

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US8937184B2 (en) * 2005-02-16 2015-01-20 Abbvie B.V. 1H-imidazole derivatives as cannabinoid CB2 receptor modulators
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WO2007024744A2 (en) * 2005-08-21 2007-03-01 Exelixis, Inc. Heterocyclic carboxamide compounds as steroid nuclear receptor ligands
US8137963B2 (en) * 2006-08-24 2012-03-20 Hiroshima University Method for highly amplifying target gene in mammalian cell and vector therefor
ES2375877T3 (es) 2006-10-31 2012-03-07 Pfizer Products Inc. Compuestos de pirazolina como antagonistas de receptores de mineralocorticoides.
EP2121621B1 (en) * 2006-12-08 2014-05-07 Exelixis Patent Company LLC Lxr and fxr modulators
TWI444185B (zh) 2007-04-09 2014-07-11 Daiichi Sankyo Co Ltd 吡咯衍生物之阻轉異構物
CA2720164A1 (en) * 2008-03-31 2009-10-08 Teva Pharmaceutical Industries Ltd. Processes for preparing sunitinib and salts thereof
EP2300457B1 (en) * 2008-06-11 2014-08-20 Genentech, Inc. Substituted pyrroles and methods of use
WO2010098286A1 (ja) * 2009-02-25 2010-09-02 第一三共株式会社 ミネラルコルチコイド受容体拮抗薬を含有する医薬
UY33200A (es) 2010-01-26 2011-08-31 Sanofi Aventis Derivados de ácido 3-heteroaroilamino-propiónico sustituidos con oxígeno y su uso como productos farmacéuticos
EP2568986B1 (en) 2010-05-10 2016-01-13 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and compositions for the treatment of fluid accumulation in and/ or under the retina
EP2582365B1 (en) 2010-06-16 2019-03-20 INSERM (Institut National de la Santé et de la Recherche Médicale) Compositions for stimulating reepithelialisation during wound healing
US20140322242A1 (en) * 2010-11-24 2014-10-30 Icahn School Of Medicine At Mount Sinai Materials and methods for the prevention and treatment of cancer
AR085013A1 (es) 2011-01-26 2013-08-07 Sanofi Aventis Derivados de acido 3-heteroaroilamino-propionico sustituidos y su uso como sustancias farmaceuticas
TWI523844B (zh) 2011-01-26 2016-03-01 賽諾菲公司 經胺基取代之３－雜芳醯基胺基－丙酸衍生物及其作為藥物之用途
EP3345901A3 (en) * 2011-06-29 2018-09-12 President and Fellows of Harvard College Small molecules as antiaging agents
MY162786A (en) 2011-07-26 2017-07-14 Sanofi Sa Substituted 3-thiazoloamino-propionic acid derivatives and their use as pharmaceuticals
WO2013014204A2 (en) 2011-07-26 2013-01-31 Sanofi 3-heteroaroylamino-propionic acid derivatives and their use as pharmaceuticals
WO2013055606A1 (en) 2011-10-13 2013-04-18 Merck Sharp & Dohme Corp. Mineralocorticoid receptor antagonists
WO2013072328A1 (en) 2011-11-14 2013-05-23 Sanofi Use of telaprevir and related compounds in atherosclerosis, heart failure, renal diseases, liver diseases or inflammatory diseases
WO2013072327A1 (en) 2011-11-14 2013-05-23 Sanofi Use of boceprevir and related compounds in atherosclerosis, heart failure, renal diseases, liver diseases or inflammatory diseases
CN104507923B (zh) * 2012-08-02 2018-02-09 内尔维阿诺医学科学有限公司 作为激酶抑制剂的取代的吡咯类活性剂
JP2016504397A (ja) 2013-01-10 2016-02-12 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング Ｃｒａｃチャネル阻害薬としての、ピラゾリルをベースとするカルボキサミド類ｉｉ
MX2015008919A (es) 2013-01-10 2015-10-22 Gruenenthal Gmbh Carboxamidas basadas en pirazolilo i como inhibidores del canal de calcio activado por liberacion de calcio (crac).
WO2014154727A1 (en) 2013-03-28 2014-10-02 Sanofi Biaryl-propionic acid derivatives and their use as pharmaceuticals
JP6359634B2 (ja) 2013-03-28 2018-07-18 サノフイ ビアリール−プロピオン酸誘導体および医薬品としてのその使用
EP3184095A1 (en) 2013-05-23 2017-06-28 IP Gesellschaft für Management mbH Administration units comprising polymorph 1 of 2-(2-methylamino-pyrimidin-4-yl]-1h-indole-5-carboxylic acid [(s)-1-carbamoyl-2-(phenyl-pyrimidin-2-yl-amino)-ethyl]-amide
WO2015197187A1 (en) 2014-06-24 2015-12-30 Grünenthal GmbH Pyrazolyl-based carboxamides v
AU2018346597B2 (en) 2017-10-06 2023-07-13 Forma Therapeutics, Inc. Inhibiting Ubiquitin Specific Peptidase 30
IL278291B2 (en) 2018-05-17 2023-10-01 Forma Therapeutics Inc Condensed bicyclic compounds are useful as ubiquitin-specific peptidase 30 inhibitors
CN108840856B (zh) * 2018-05-31 2019-12-24 陈�峰 一种酯类衍生物及其在防治心脑血管疾病中的应用
CN108822079B (zh) * 2018-05-31 2019-12-06 陈刚 一种酯类衍生物及其在防治心脑血管疾病中的应用
EP4218934B1 (en) 2018-10-05 2025-06-18 Forma Therapeutics, Inc. Inhibiting ubiquitin-specific protease 30 (usp30)
AU2020371836B2 (en) * 2019-10-25 2026-01-29 Sunshine Lake Pharma Co., Ltd. Pyrrole amide compound and use thereof
US20240239746A1 (en) * 2021-04-26 2024-07-18 Sunshine Lake Pharma Co., Ltd. Preparation method for pyrrole amide compound
CN115784961B (zh) * 2021-09-10 2026-03-31 上海鼎雅药物化学科技有限公司 埃沙西林酮及其中间体的合成方法
CN113929591A (zh) * 2021-10-09 2022-01-14 中国科学技术大学 具有抗增殖活性的抑制剂

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US7119108B1 (en) * 1999-10-18 2006-10-10 University Of Connecticut Pyrazole derivatives as cannabinoid receptor antagonists
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AU2002319627A1 (en) * 2001-07-20 2003-03-03 Merck And Co., Inc. Substituted imidazoles as cannabinoid receptor modulators
TWI231757B (en) * 2001-09-21 2005-05-01 Solvay Pharm Bv 1H-Imidazole derivatives having CB1 agonistic, CB1 partial agonistic or CB1-antagonistic activity
AU2003209388A1 (en) * 2002-01-29 2003-09-02 Merck And Co., Inc. Substituted imidazoles as cannabinoid receptor modulators
JP2004189738A (ja) * 2002-11-29 2004-07-08 Nippon Nohyaku Co Ltd 置換アニリド誘導体、その中間体及び農園芸用薬剤並びにその使用方法
EP1608637A1 (de) * 2003-03-24 2005-12-28 Basf Aktiengesellschaft Trifluormethyl-thiophencarbonsäureanilide und ihre verwendung als fungizide
EP1653949A4 (en) * 2003-08-07 2009-04-22 Merck & Co Inc PYRAZOL CARBOXAMIDE AS AN INHIBITOR OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE-1
PT1773768T (pt) * 2004-07-30 2018-11-30 Exelixis Inc Derivados de pirrol como agentes farmacêuticos

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