JP2008526869A5 - - Google Patents

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Publication number
JP2008526869A5
JP2008526869A5 JP2007550462A JP2007550462A JP2008526869A5 JP 2008526869 A5 JP2008526869 A5 JP 2008526869A5 JP 2007550462 A JP2007550462 A JP 2007550462A JP 2007550462 A JP2007550462 A JP 2007550462A JP 2008526869 A5 JP2008526869 A5 JP 2008526869A5
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JP
Japan
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optionally substituted
heterocyclyl
aryl
alkyl
heteroaryl
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JP2007550462A
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English (en)
Japanese (ja)
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JP2008526869A (ja
JP5123668B2 (ja
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Priority claimed from PCT/US2006/000319 external-priority patent/WO2006076202A1/en
Publication of JP2008526869A publication Critical patent/JP2008526869A/ja
Publication of JP2008526869A5 publication Critical patent/JP2008526869A5/ja
Application granted granted Critical
Publication of JP5123668B2 publication Critical patent/JP5123668B2/ja
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JP2007550462A 2005-01-10 2006-01-06 医薬品としての複素環カルボキサミド化合物 Active JP5123668B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US64283905P 2005-01-10 2005-01-10
US60/642,839 2005-01-10
PCT/US2006/000319 WO2006076202A1 (en) 2005-01-10 2006-01-06 Heterocyclic carboxamide compounds as steroid nuclear receptors ligands

Publications (3)

Publication Number Publication Date
JP2008526869A JP2008526869A (ja) 2008-07-24
JP2008526869A5 true JP2008526869A5 (enExample) 2009-03-19
JP5123668B2 JP5123668B2 (ja) 2013-01-23

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ID=36178222

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007550462A Active JP5123668B2 (ja) 2005-01-10 2006-01-06 医薬品としての複素環カルボキサミド化合物

Country Status (6)

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US (1) US20110144128A1 (enExample)
EP (1) EP1844020B1 (enExample)
JP (1) JP5123668B2 (enExample)
AU (1) AU2006205220B2 (enExample)
CA (1) CA2593156C (enExample)
WO (1) WO2006076202A1 (enExample)

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MX2008000141A (es) 2005-06-27 2008-04-07 Exelixis Inc Moduladores de lxr basados en imidazol.
WO2007024744A2 (en) * 2005-08-21 2007-03-01 Exelixis, Inc. Heterocyclic carboxamide compounds as steroid nuclear receptor ligands
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HRP20120078T1 (hr) 2006-10-31 2012-02-29 Pfizer Products Inc. Pirazolinski spojevi kao antagonisti mineralokortikoidnih receptora
EP2121621B1 (en) * 2006-12-08 2014-05-07 Exelixis Patent Company LLC Lxr and fxr modulators
PT2133330E (pt) 2007-04-09 2014-03-31 Daiichi Sankyo Co Ltd Atropisómero de derivado de pirrole
CA2720164A1 (en) * 2008-03-31 2009-10-08 Teva Pharmaceutical Industries Ltd. Processes for preparing sunitinib and salts thereof
US8410279B2 (en) * 2008-06-11 2013-04-02 Genentech, Inc. Substituted pyrroles and methods of use
WO2010098286A1 (ja) * 2009-02-25 2010-09-02 第一三共株式会社 ミネラルコルチコイド受容体拮抗薬を含有する医薬
AR079967A1 (es) 2010-01-26 2012-02-29 Sanofi Aventis Derivados de acido 3-heteroaroilamino-propionico sustituidos con oxigeno y su uso como productos farmaceuticos
EP2977084B1 (en) 2010-05-10 2017-07-05 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and compositions for the treatment of fluid accumulation in and/ or under the retina
WO2011157798A1 (en) 2010-06-16 2011-12-22 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and compositions for stimulating reepithelialisation during wound healing
WO2012071573A2 (en) * 2010-11-24 2012-05-31 Mount Sinai School Of Medicine Materials and methods for the prevention and treatment of cancer
TWI523844B (zh) 2011-01-26 2016-03-01 賽諾菲公司 經胺基取代之３－雜芳醯基胺基－丙酸衍生物及其作為藥物之用途
US8669370B2 (en) 2011-01-26 2014-03-11 Sanofi Substituted 3-heteroaroylamino-propionic acid derivatives and their use as pharmaceuticals
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CN103827098B (zh) 2011-07-26 2016-06-15 赛诺菲 取代的3-(噻唑-4-羰基)-或者3-(噻唑-2-羰基)-氨基丙酸衍生物及其作为药物的用途
WO2013014204A2 (en) 2011-07-26 2013-01-31 Sanofi 3-heteroaroylamino-propionic acid derivatives and their use as pharmaceuticals
WO2013055606A1 (en) 2011-10-13 2013-04-18 Merck Sharp & Dohme Corp. Mineralocorticoid receptor antagonists
US20130123325A1 (en) 2011-11-14 2013-05-16 Sven Ruf Use of boceprevir and related compounds in atherosclerosis, heart failure, renal diseases, liver diseases or inflammatory diseases
US20130123276A1 (en) 2011-11-14 2013-05-16 Sven Ruf Use of telaprevir and related compounds in atherosclerosis, heart failure, renal diseases, liver diseases or inflammatory diseases
DK2880025T3 (en) * 2012-08-02 2019-03-18 Nerviano Medical Sciences Srl SUBSTITUTED PYROLES ACTIVE AS KINase INHIBITORS
WO2014108337A1 (en) 2013-01-10 2014-07-17 Grünenthal GmbH Pyrazolyl-based carboxamides i as crac channel inhibitors
WO2014108336A1 (en) 2013-01-10 2014-07-17 Grünenthal GmbH Pyrazolyl-based carboxamides ii as crac channel inhibitors
AU2014243070B2 (en) 2013-03-28 2017-12-21 Sanofi Biaryl-propionic acid derivatives and their use as pharmaceuticals
WO2014154726A1 (en) 2013-03-28 2014-10-02 Sanofi Biaryl-propionic acid derivatives and their use as pharmaceuticals
EP2805705B1 (en) 2013-05-23 2016-11-09 IP Gesellschaft für Management mbH Packaging with one or more administration units comprising a sodium salt of (R)-3-[6-amino-pyridin-3-yl]-2-(1-cyclohexyl-1 H-imidazol-4-yl)-propionic acid
WO2015197187A1 (en) 2014-06-24 2015-12-30 Grünenthal GmbH Pyrazolyl-based carboxamides v
ES2950757T3 (es) 2017-10-06 2023-10-13 Forma Therapeutics Inc Inhibición de la peptidasa específica de la ubiquitina 30
BR112020021921A2 (pt) 2018-05-17 2021-01-26 Forma Therapeutics, Inc. compostos bicíclicos fundidos úteis como inibidores de peptidase 30 específica de ubiquitina
CN108840856B (zh) * 2018-05-31 2019-12-24 陈�峰 一种酯类衍生物及其在防治心脑血管疾病中的应用
CN108822079B (zh) * 2018-05-31 2019-12-06 陈刚 一种酯类衍生物及其在防治心脑血管疾病中的应用
LT3860989T (lt) 2018-10-05 2023-06-12 Forma Therapeutics, Inc. Sulieti pirolinai, kurie veikia kaip ubikvitinui specifinės proteazės 30 (ups30) inhibitoriai
CN112707854B (zh) * 2019-10-25 2022-03-15 年衍药业(珠海)有限公司 吡咯酰胺类化合物及其用途
US20240239746A1 (en) * 2021-04-26 2024-07-18 Sunshine Lake Pharma Co., Ltd. Preparation method for pyrrole amide compound
CN115784961A (zh) * 2021-09-10 2023-03-14 上海鼎雅药物化学科技有限公司 埃沙西林酮及其中间体的合成方法
CN113929591A (zh) * 2021-10-09 2022-01-14 中国科学技术大学 具有抗增殖活性的抑制剂

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AU2004265299B2 (en) * 2003-08-07 2008-05-01 Merck & Co., Inc. Pyrazole carboxamides as inhibitors of 11-beta-hydroxysteroid dehydrogenase-1
WO2006012642A2 (en) * 2004-07-30 2006-02-02 Exelixis, Inc. Pyrrole derivatives as pharmaceutical agents

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