|
BRPI0406761A
(pt)
|
2003-01-14 |
2005-12-20 |
Arena Pharm Inc |
Derivados de arila e heteroarila 1,2,3-trissubstituìdos como moduladores do metabolismo e a profilaxia e tratamento de distúrbios relacionados a estes tais como diabetes e hiper-glicemia
|
|
AR045047A1
(es)
|
2003-07-11 |
2005-10-12 |
Arena Pharm Inc |
Derivados arilo y heteroarilo trisustituidos como moduladores del metabolismo y de la profilaxis y tratamiento de desordenes relacionados con los mismos
|
|
DK2559690T3
(en)
|
2005-05-10 |
2016-04-25 |
Incyte Holdings Corp |
Modulators of indoleamine 2,3-dioxygenase and methods of use thereof
|
|
US20090221644A1
(en)
*
|
2005-06-30 |
2009-09-03 |
Stuart Edward Bradley |
Gpcr Agonists
|
|
ES2540561T3
(es)
|
2005-12-20 |
2015-07-10 |
Incyte Corporation |
N-hidroxiamidinoheterociclos como moduladores de indolamina 2,3-dioxigenasa
|
|
AU2006326815A1
(en)
*
|
2005-12-20 |
2007-06-28 |
Merck Frosst Canada Ltd. |
Heteroaromatic compounds as inhibitors of stearoyl-coenzyme A delta-9 desaturase
|
|
PE20071221A1
(es)
|
2006-04-11 |
2007-12-14 |
Arena Pharm Inc |
Agonistas del receptor gpr119 en metodos para aumentar la masa osea y para tratar la osteoporosis y otras afecciones caracterizadas por masa osea baja, y la terapia combinada relacionada a estos agonistas
|
|
ATE487940T1
(de)
|
2006-04-11 |
2010-11-15 |
Arena Pharm Inc |
Verfahren zur verwendung des gpr119-rezeptors zur identifizierung von verbindungen zur erhöhung der knochenmasse bei einer person
|
|
FR2903405B1
(fr)
|
2006-07-04 |
2011-09-09 |
Pasteur Institut |
Composes a effet potentialisateur de l'activite de l'ethionamide et leurs applications
|
|
AU2007283113A1
(en)
|
2006-08-08 |
2008-02-14 |
Sanofi-Aventis |
Arylaminoaryl-alkyl-substituted imidazolidine-2,4-diones, processes for preparing them, medicaments comprising these compounds, and their use
|
|
CL2007002650A1
(es)
|
2006-09-19 |
2008-02-08 |
Incyte Corp |
Compuestos derivados de heterociclo n-hidroxiamino; composicion farmaceutica, util para tratar cancer, infecciones virales y desordenes neurodegenerativos entre otras.
|
|
US20080125470A1
(en)
|
2006-09-19 |
2008-05-29 |
Incyte Corporation |
N-hydroxyamidinoheterocycles as modulators of indoleamine 2,3-dioxygenase
|
|
AU2007334519A1
(en)
|
2006-12-14 |
2008-06-26 |
Merck Sharp & Dohme Corp. |
Acyl bipiperidinyl compounds, compositions containing such compounds and methods of treatment
|
|
CL2008000017A1
(es)
|
2007-01-04 |
2008-08-01 |
Prosidion Ltd |
Compuestos derivados de heterociclos de nitrogeno y oxigeno, agonistas de gpcr; composicion farmaceutica que comprende a dicho compuesto; y uso del compuesto para el tratamiento de la obesidad, diabetes, sindrome metabolico, hiperlipidemia, toleranci
|
|
GB0700122D0
(en)
|
2007-01-04 |
2007-02-14 |
Prosidion Ltd |
GPCR agonists
|
|
BRPI0806312A2
(pt)
*
|
2007-01-04 |
2011-09-06 |
Prosidion Ltd |
agonistas cgpr piperidina
|
|
CL2008000018A1
(es)
|
2007-01-04 |
2008-08-01 |
Prosidion Ltd |
Compuestos derivados de heterociclos de nitrogeno y oxigeno, agonistas de gpcr; composicion farmaceutica que comprende a dicho compuesto; y uso del compuesto para el tratamiento de la obesidad, diabetes, sindrome metabolico, hiperlipidemia, toleranci
|
|
JP2010514828A
(ja)
|
2007-01-04 |
2010-05-06 |
プロシディオン・リミテッド |
ピペリジンgpcrアゴニスト
|
|
CN101668756A
(zh)
|
2007-05-04 |
2010-03-10 |
百时美施贵宝公司 |
[6,6]和[6,7]-双环gpr119 g蛋白偶合受体激动剂
|
|
EP2152707B1
(en)
|
2007-05-04 |
2012-06-20 |
Bristol-Myers Squibb Company |
[6,5]-bicyclic gpr119 g protein-coupled receptor agonists
|
|
HRP20110806T1
(hr)
|
2007-07-17 |
2011-11-30 |
Bristol-Myers Squibb Company |
Agonisti piridon gpr119 g protein-vezanih receptora
|
|
EP2025674A1
(de)
|
2007-08-15 |
2009-02-18 |
sanofi-aventis |
Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
|
EP2200609A1
(en)
|
2007-09-10 |
2010-06-30 |
Prosidion Limited |
Compounds for the treatment of metabolic disorders
|
|
GB0720389D0
(en)
|
2007-10-18 |
2008-11-12 |
Prosidion Ltd |
G-Protein Coupled Receptor Agonists
|
|
GB0720390D0
(en)
|
2007-10-18 |
2007-11-28 |
Prosidion Ltd |
G-Protein coupled receptor agonists
|
|
DE102007054497B3
(de)
|
2007-11-13 |
2009-07-23 |
Sanofi-Aventis Deutschland Gmbh |
Neue kristalline Diphenylazetidinonhydrate und Verfahren zu deren Herstellung
|
|
KR20100115378A
(ko)
*
|
2008-02-22 |
2010-10-27 |
아이알엠 엘엘씨 |
Gpr119 활성의 조절제로서의 화합물 및 조성물
|
|
WO2009106565A1
(en)
*
|
2008-02-27 |
2009-09-03 |
Biovitrum Ab (Publ) |
Agonists of gpr119
|
|
EP2108960A1
(en)
|
2008-04-07 |
2009-10-14 |
Arena Pharmaceuticals, Inc. |
Methods of using A G protein-coupled receptor to identify peptide YY (PYY) secretagogues and compounds useful in the treatment of conditons modulated by PYY
|
|
US8343990B2
(en)
|
2008-04-14 |
2013-01-01 |
Merck Sharp & Dohme Corp. |
Substituted cyclopropyl compounds, compositions containing such compounds and methods of treatment
|
|
WO2009150144A1
(en)
*
|
2008-06-10 |
2009-12-17 |
Inovacia Ab |
New gpr119modulators
|
|
NZ590268A
(en)
|
2008-07-08 |
2012-11-30 |
Incyte Corp |
1,2,5-oxadiazoles as inhibitors of indoleamine 2,3-dioxygenase
|
|
US8470841B2
(en)
|
2008-07-09 |
2013-06-25 |
Sanofi |
Heterocyclic compounds, processes for their preparation, medicaments comprising these compounds, and the use thereof
|
|
TW201006821A
(en)
|
2008-07-16 |
2010-02-16 |
Bristol Myers Squibb Co |
Pyridone and pyridazone analogues as GPR119 modulators
|
|
AU2009270983A1
(en)
*
|
2008-07-16 |
2010-01-21 |
Schering Corporation |
Bicyclic heterocycle derivatives and their use as GPCR modulators
|
|
WO2010068601A1
(en)
|
2008-12-08 |
2010-06-17 |
Sanofi-Aventis |
A crystalline heteroaromatic fluoroglycoside hydrate, processes for making, methods of use and pharmaceutical compositions thereof
|
|
GB0904287D0
(en)
|
2009-03-12 |
2009-04-22 |
Prosidion Ltd |
Compounds for the treatment of metabolic disorders
|
|
GB0904284D0
(en)
|
2009-03-12 |
2009-04-22 |
Prosidion Ltd |
Compounds for the treatment of metabolic disorders
|
|
GB0904285D0
(en)
|
2009-03-12 |
2009-04-22 |
Prosidion Ltd |
Compounds for the treatment of metabolic disorders
|
|
US8481731B2
(en)
|
2009-06-24 |
2013-07-09 |
Boehringer Ingelheim International Gmbh |
Compounds, pharmaceutical composition and methods relating thereto
|
|
US8293729B2
(en)
|
2009-06-24 |
2012-10-23 |
Boehringer Ingelheim International Gmbh |
Compounds, pharmaceutical composition and methods relating thereto
|
|
JP2013503135A
(ja)
|
2009-08-26 |
2013-01-31 |
サノフイ |
新規な結晶性複素芳香族フルオログリコシド水和物、その化合物を含んでなる医薬及びその使用
|
|
WO2011107494A1
(de)
|
2010-03-03 |
2011-09-09 |
Sanofi |
Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
|
|
US20130005979A1
(en)
*
|
2010-03-15 |
2013-01-03 |
Kuraray Co. Ltd. |
Thienopyridine derivative, method for producing same and organic semiconductor device using same
|
|
US20130109703A1
(en)
|
2010-03-18 |
2013-05-02 |
Boehringer Ingelheim International Gmbh |
Combination of a GPR119 Agonist and the DPP-IV Inhibitor Linagliptin for Use in the Treatment of Diabetes and Related Conditions
|
|
PH12012501853A1
(en)
|
2010-04-08 |
2013-01-07 |
Bristol Myers Squibb Co |
Pyrimidinylpiperidinyloxypyridinone analogues as gpr119 modulators
|
|
GB201006166D0
(en)
|
2010-04-14 |
2010-05-26 |
Prosidion Ltd |
Compounds for the treatment of metabolic disorders
|
|
GB201006167D0
(en)
|
2010-04-14 |
2010-05-26 |
Prosidion Ltd |
Compounds for the treatment of metabolic disorders
|
|
EA201270778A1
(ru)
*
|
2010-05-06 |
2013-04-30 |
Бристол-Майерс Сквибб Компани |
Бициклические гетероарильные аналоги в качестве модуляторов рецептора gpr119
|
|
TW201209054A
(en)
|
2010-05-28 |
2012-03-01 |
Prosidion Ltd |
Novel compounds
|
|
EP2582709B1
(de)
|
2010-06-18 |
2018-01-24 |
Sanofi |
Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen
|
|
US8530413B2
(en)
|
2010-06-21 |
2013-09-10 |
Sanofi |
Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
|
|
TW201221505A
(en)
|
2010-07-05 |
2012-06-01 |
Sanofi Sa |
Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
|
|
TW201215387A
(en)
|
2010-07-05 |
2012-04-16 |
Sanofi Aventis |
Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
|
|
TW201215388A
(en)
|
2010-07-05 |
2012-04-16 |
Sanofi Sa |
(2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
|
|
WO2012020725A1
(ja)
*
|
2010-08-10 |
2012-02-16 |
塩野義製薬株式会社 |
Npy y5受容体拮抗作用を有するヘテロ環誘導体
|
|
SG188548A1
(en)
|
2010-09-22 |
2013-04-30 |
Arena Pharm Inc |
Modulators of the gpr119 receptor and the treatment of disorders related thereto
|
|
GB201114389D0
(en)
|
2011-08-22 |
2011-10-05 |
Prosidion Ltd |
Novel compounds
|
|
AR083904A1
(es)
|
2010-11-18 |
2013-04-10 |
Prosidion Ltd |
Derivados de 1,4-pirrolidinas disustituidos y 3-il-aminas y sus usos en el tratamiento de desordenes metabolicos
|
|
EP2683703B1
(de)
|
2011-03-08 |
2015-05-27 |
Sanofi |
Neue substituierte phenyl-oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
|
|
EP2766349B1
(de)
|
2011-03-08 |
2016-06-01 |
Sanofi |
Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
|
|
EP2683704B1
(de)
|
2011-03-08 |
2014-12-17 |
Sanofi |
Verzweigte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
|
|
EP2683698B1
(de)
|
2011-03-08 |
2017-10-04 |
Sanofi |
Mit adamantan- oder noradamantan substituierte benzyl-oxathiazinderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
|
|
WO2012120056A1
(de)
|
2011-03-08 |
2012-09-13 |
Sanofi |
Tetrasubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
|
|
US8809324B2
(en)
|
2011-03-08 |
2014-08-19 |
Sanofi |
Substituted phenyl-oxathiazine derivatives, method for producing them, drugs containing said compounds and the use thereof
|
|
WO2012120058A1
(de)
|
2011-03-08 |
2012-09-13 |
Sanofi |
Mit benzyl- oder heteromethylengruppen substituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
|
|
WO2012120054A1
(de)
|
2011-03-08 |
2012-09-13 |
Sanofi |
Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
|
|
EP2683699B1
(de)
|
2011-03-08 |
2015-06-24 |
Sanofi |
Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
|
|
US8957062B2
(en)
|
2011-04-08 |
2015-02-17 |
Merck Sharp & Dohme Corp. |
Substituted cyclopropyl compounds, compositions containing such compounds and methods of treatment
|
|
WO2012173917A1
(en)
|
2011-06-16 |
2012-12-20 |
Merck Sharp & Dohme Corp. |
Substituted cyclopropyl compounds, compositions containing such compounds, and methods of treatment
|
|
WO2013037390A1
(en)
|
2011-09-12 |
2013-03-21 |
Sanofi |
6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
|
|
EP2567959B1
(en)
|
2011-09-12 |
2014-04-16 |
Sanofi |
6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
|
|
WO2013045413A1
(en)
|
2011-09-27 |
2013-04-04 |
Sanofi |
6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
|
|
EP2760855B1
(en)
|
2011-09-30 |
2017-03-15 |
Merck Sharp & Dohme Corp. |
Substituted cyclopropyl compounds, compositions containing such compounds as well as their use in treating type-2 diabetes
|
|
US9018200B2
(en)
|
2011-10-24 |
2015-04-28 |
Merck Sharp & Dohme Corp. |
Substituted piperidinyl compounds useful as GPR119 agonists
|
|
US9018224B2
(en)
|
2011-11-15 |
2015-04-28 |
Merck Sharp & Dohme Corp. |
Substituted cyclopropyl compounds useful as GPR119 agonists
|
|
EP2876109A4
(en)
*
|
2012-07-23 |
2016-03-16 |
Yuhan Corp |
CONDENSED RING CONNECTION WITH FURAN OR SALT AND PHARMACEUTICAL COMPOSITIONS THEREWITH
|
|
BR112016004889B1
(pt)
|
2013-09-06 |
2023-10-03 |
Aurigene Discovery Technologies Limited |
Derivados de 1,2,4-oxadiazol como imunomoduladores
|
|
CR20160252A
(es)
|
2013-11-08 |
2016-09-19 |
Incyte Holdings Corp |
Proceso para la sintesis de un inhibidor de indolamina 2,3-dioxigenasa
|
|
AU2016205361C1
(en)
|
2015-01-06 |
2021-04-08 |
Arena Pharmaceuticals, Inc. |
Methods of treating conditions related to the S1P1 receptor
|
|
EP4023645A1
(en)
|
2015-03-10 |
2022-07-06 |
Aurigene Discovery Technologies Limited |
1,2,4-oxadiazole and thiadiazole compounds as immunomodulators
|
|
US20180044329A1
(en)
*
|
2015-03-10 |
2018-02-15 |
Aurigene Discovery Technologies Limited |
3-substituted-1,2,4-oxadiazole and thiadiazole compounds as immunomodulators
|
|
CA3002551A1
(en)
|
2015-06-22 |
2016-12-29 |
Arena Pharmaceuticals, Inc. |
Crystalline l-arginine salt of (r)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclo-penta[b]indol-3-yl)acetic acid(com pound 1)for use in s1p1 receptor-associated disorders
|
|
CA3053418A1
(en)
|
2017-02-16 |
2018-08-23 |
Arena Pharmaceuticals, Inc. |
Compounds and methods for treatment of primary biliary cholangitis
|
|
WO2019061324A1
(en)
|
2017-09-29 |
2019-04-04 |
Curis Inc. |
CRYSTALLINE FORMS OF IMMUNOMODULATORS
|
|
KR102838640B1
(ko)
|
2017-10-11 |
2025-07-24 |
오리진 온콜로지 리미티드 |
3-치환된 1,2,4-옥사다이아졸의 결정질 형태
|
|
SG11202003625VA
(en)
|
2017-11-03 |
2020-05-28 |
Aurigene Discovery Tech Ltd |
Dual inhibitors of tim-3 and pd-1 pathways
|
|
CN111386128A
(zh)
|
2017-11-06 |
2020-07-07 |
奥瑞基尼探索技术有限公司 |
用于免疫调节的联合疗法
|
|
CA3102136A1
(en)
|
2018-06-06 |
2019-12-12 |
Arena Pharmaceuticals, Inc. |
Methods of treating conditions related to the s1p1 receptor
|
|
CN112839648B
(zh)
|
2018-06-07 |
2025-04-04 |
达萨玛治疗公司 |
Sarm1抑制剂
|
|
EP3897670A4
(en)
|
2018-12-19 |
2022-09-07 |
Disarm Therapeutics, Inc. |
MRSA1 INHIBITORS IN COMBINATION WITH NEUROPROTECTIVE AGENTS
|