JP2018525375A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2018525375A5 JP2018525375A5 JP2018505409A JP2018505409A JP2018525375A5 JP 2018525375 A5 JP2018525375 A5 JP 2018525375A5 JP 2018505409 A JP2018505409 A JP 2018505409A JP 2018505409 A JP2018505409 A JP 2018505409A JP 2018525375 A5 JP2018525375 A5 JP 2018525375A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- methyl
- phenylamino
- pyridin
- independently
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- CUYKNJBYIJFRCU-UHFFFAOYSA-N Nc1cccnc1 Chemical compound Nc1cccnc1 CUYKNJBYIJFRCU-UHFFFAOYSA-N 0.000 description 2
- JUJWROOIHBZHMG-UHFFFAOYSA-N c1ccncc1 Chemical compound c1ccncc1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 description 2
- 0 CCC(*)(C(CN1*)C(C)=*)C1=O Chemical compound CCC(*)(C(CN1*)C(C)=*)C1=O 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15179859.2 | 2015-08-05 | ||
| EP15179859 | 2015-08-05 | ||
| EP15200620.1 | 2015-12-16 | ||
| EP15200620 | 2015-12-16 | ||
| PCT/EP2016/068279 WO2017021348A1 (en) | 2015-08-05 | 2016-08-01 | 1h-pyrrol-3-amines |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2018525375A JP2018525375A (ja) | 2018-09-06 |
| JP2018525375A5 true JP2018525375A5 (enExample) | 2019-06-13 |
Family
ID=56611249
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018505409A Withdrawn JP2018525375A (ja) | 2015-08-05 | 2016-08-01 | １ｈ−ピロール−３−アミン類 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US10308629B2 (enExample) |
| EP (1) | EP3331611B1 (enExample) |
| JP (1) | JP2018525375A (enExample) |
| CN (1) | CN107921286A (enExample) |
| CA (1) | CA2994596A1 (enExample) |
| WO (1) | WO2017021348A1 (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2708211T3 (es) | 2014-06-17 | 2019-04-09 | Bayer Pharma AG | 3-amino-1,5,6,7-tetrahidro-4H-indol-4-onas |
| AU2016212230B2 (en) | 2015-01-28 | 2019-09-19 | Bayer Pharma Aktiengesellschaft | 4H-pyrrolo[3,2-c]pyridin-4-one derivatives |
| US10227299B2 (en) | 2015-06-17 | 2019-03-12 | Bayer Pharma Aktiengesellschaft | 3-amino-1,5,6,7-tetrahydro-4H-indol-4-ones |
| TWI808055B (zh) | 2016-05-11 | 2023-07-11 | 美商滬亞生物國際有限公司 | Hdac 抑制劑與 pd-1 抑制劑之組合治療 |
| TWI794171B (zh) | 2016-05-11 | 2023-03-01 | 美商滬亞生物國際有限公司 | Ｈｄａｃ抑制劑與ｐｄ-ｌ１抑制劑之組合治療 |
| WO2018158175A1 (en) | 2017-02-28 | 2018-09-07 | Bayer Pharma Aktiengesellschaft | Combination of bub1 inhibitors |
| WO2018206547A1 (en) | 2017-05-12 | 2018-11-15 | Bayer Pharma Aktiengesellschaft | Combination of bub1 and atr inhibitors |
| WO2018215282A1 (en) | 2017-05-26 | 2018-11-29 | Bayer Pharma Aktiengesellschaft | Combination of bub1 and pi3k inhibitors |
| CA3196712A1 (en) | 2020-09-23 | 2022-03-31 | Scorpion Therapeutics, Inc. | Pyrrolo[3,2-c]pyridin-4-one derivatives useful in the treatment of cancer |
| WO2022072645A2 (en) | 2020-09-30 | 2022-04-07 | Scorpion Therapeutics, Inc. | Methods for treating cancer |
| WO2022072634A1 (en) | 2020-09-30 | 2022-04-07 | Scorpion Therapeutics, Inc. | Bicyclic compounds for use in the treatment cancer |
| US11767321B2 (en) | 2020-10-05 | 2023-09-26 | Enliven Inc. | 5- and 6-azaindole compounds for inhibition of BCR-ABL tyrosine kinases |
| TW202227063A (zh) | 2020-10-09 | 2022-07-16 | 美商史考皮恩治療有限公司 | 治療癌症之方法 |
| WO2022094271A1 (en) | 2020-10-30 | 2022-05-05 | Scorpion Therapeutics, Inc. | Methods for treating cancer |
| WO2022098992A1 (en) | 2020-11-05 | 2022-05-12 | Scorpion Therapeutics, Inc. | Use of macrocyclic compounds in methods of treating cancer |
| WO2022197913A1 (en) | 2021-03-18 | 2022-09-22 | Scorpion Therapeutics, Inc. | Bicyclic derivatives which can be used to treat cancer |
| WO2023173083A1 (en) | 2022-03-11 | 2023-09-14 | Scorpion Therapeutics, Inc. | Tetrahydroindole derivatives as egfr and/or her2 inhibtors useful for the treatment of cancer |
| WO2024159094A1 (en) * | 2023-01-27 | 2024-08-02 | Enliven Inc. | Pyrimidinyl (hetero)aromatic aminopyridine compounds for inhibition of raf kinases |
| EP4724151A1 (en) | 2023-06-08 | 2026-04-15 | Antares Therapeutics, Inc. | A 1,5-dihydro-4h-pyrrolo[3,2-c] pyridin-4-one for use in the treatment of cancer |
| CN121712773A (zh) | 2023-06-08 | 2026-03-20 | 安塔列斯疗法股份有限公司 | 1,5-二氢-4h-吡咯并[3,2-c]吡啶-4-酮用于癌症治疗 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010145998A1 (en) | 2009-06-15 | 2010-12-23 | Nerviano Medical Sciences S.R.L. | Substituted pyrimidinylpyrrolopyridinone derivatives, process for their preparation and their use as kinase inhibitors |
| HK1207861A1 (en) | 2012-05-11 | 2016-02-12 | Bayer Pharma Aktiengesellschaft | Substituted cycloalkenopyrazoles as bub1 inhibitors for the treatment of cancer |
| AR097325A1 (es) * | 2013-08-13 | 2016-03-09 | Gruenenthal Gmbh | Pirroles anillados |
| ES2708211T3 (es) | 2014-06-17 | 2019-04-09 | Bayer Pharma AG | 3-amino-1,5,6,7-tetrahidro-4H-indol-4-onas |
| AU2016212230B2 (en) * | 2015-01-28 | 2019-09-19 | Bayer Pharma Aktiengesellschaft | 4H-pyrrolo[3,2-c]pyridin-4-one derivatives |
-
2016
- 2016-08-01 CA CA2994596A patent/CA2994596A1/en not_active Abandoned
- 2016-08-01 CN CN201680046028.6A patent/CN107921286A/zh active Pending
- 2016-08-01 EP EP16748101.9A patent/EP3331611B1/en active Active
- 2016-08-01 US US15/750,103 patent/US10308629B2/en not_active Expired - Fee Related
- 2016-08-01 WO PCT/EP2016/068279 patent/WO2017021348A1/en not_active Ceased
- 2016-08-01 JP JP2018505409A patent/JP2018525375A/ja not_active Withdrawn
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| KR102396930B1 (ko) | 피리도[3,4-d]피리미딘 유도체 및 이를 포함하는 치료용 약학 조성물 | |
| JP7427098B2 (ja) | タンパク質キナ－ゼ阻害活性を有する７－アミノ－３，４－ジヒドロピリミドピリミジン－２－オン誘導体およびこれを含む治療用薬学組成物 | |
| JP3649395B2 (ja) | 縮合ヘテロアリール誘導体 | |
| JP2016525075A5 (enExample) | ||
| TWI520962B (zh) | As the c-Met tyrosine kinase inhibitors novel fused pyridine derivatives | |
| AU2022207648A1 (en) | Isoindolinone compounds | |
| KR102845791B1 (ko) | 일종의 신형 퀴놀린 유도체 억제제 | |
| RU2018134981A (ru) | Конъюгаты, содержащие ингибиторы RIPK2 | |
| JP2007516194A5 (enExample) | ||
| WO2018214867A9 (zh) | N-(氮杂芳基)环内酰胺-1-甲酰胺衍生物及其制备方法和应用 | |
| JP2007519694A5 (enExample) | ||
| JP2014513112A5 (enExample) | ||
| CN103124730A (zh) | 杂环炔苯类化合物及其药用组合物和应用 | |
| CN107428690A (zh) | 可用于治疗癌症的突变idh1抑制剂 | |
| KR20220024014A (ko) | Acss2 저해제 및 이의 사용 방법 | |
| JP2019512535A5 (enExample) | ||
| US20130310374A1 (en) | Substituted Imidazoquinoline Derivatives | |
| AU2012250059A1 (en) | Aldosterone synthase inhibitors | |
| KR102864783B1 (ko) | 피라졸로피리다지논 화합물, 그의 약학적 조성물 및 그의 용도 | |
| AU2020342108B2 (en) | Compound having Axl and c-Met kinase inhibitory activity, preparation thereof and application thereof | |
| US9567333B2 (en) | Triazolopyridyl compounds as aldosterone synthase inhibitors | |
| EP4323349A1 (en) | Isoindolinone amide compounds useful to treat diseases associated with gspt1 | |
| KR102940213B1 (ko) | Nadph 산화효소 저해제로서의 신규한 화합물 | |
| WO2018214866A9 (zh) | 一种氮杂芳基衍生物、其制备方法和在药学上的应用 | |
| JP2016540803A5 (enExample) |