FR2903405B1 - Composes a effet potentialisateur de l'activite de l'ethionamide et leurs applications - Google Patents
Composes a effet potentialisateur de l'activite de l'ethionamide et leurs applicationsInfo
- Publication number
- FR2903405B1 FR2903405B1 FR0606088A FR0606088A FR2903405B1 FR 2903405 B1 FR2903405 B1 FR 2903405B1 FR 0606088 A FR0606088 A FR 0606088A FR 0606088 A FR0606088 A FR 0606088A FR 2903405 B1 FR2903405 B1 FR 2903405B1
- Authority
- FR
- France
- Prior art keywords
- compounds
- applications
- potentiating effect
- ethionamide
- activity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 150000001875 compounds Chemical class 0.000 title 1
- 230000000694 effects Effects 0.000 title 1
- AEOCXXJPGCBFJA-UHFFFAOYSA-N ethionamide Chemical compound CCC1=CC(C(N)=S)=CC=N1 AEOCXXJPGCBFJA-UHFFFAOYSA-N 0.000 title 1
- 229960002001 ethionamide Drugs 0.000 title 1
- 230000003389 potentiating effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
- A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/08—Antibacterial agents for leprosy
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Priority Applications (13)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0606088A FR2903405B1 (fr) | 2006-07-04 | 2006-07-04 | Composes a effet potentialisateur de l'activite de l'ethionamide et leurs applications |
JP2009517335A JP2009541474A (ja) | 2006-07-04 | 2007-07-04 | エチオナミド活性の増強効果を有する化合物及びその使用 |
CNA2007800326714A CN101516876A (zh) | 2006-07-04 | 2007-07-04 | 具有乙硫异烟胺活性增强作用的化合物及其用途 |
AP2009004747A AP2009004747A0 (en) | 2006-07-04 | 2007-07-04 | Compounds having a potentiating effect on the activity of ethoionamide and uses thereof |
KR1020097002316A KR20090043506A (ko) | 2006-07-04 | 2007-07-04 | 에티온아미드 활성 강화 효과를 갖는 화합물 및 그 용도 |
US12/306,333 US8338599B2 (en) | 2006-07-04 | 2007-07-04 | Compounds having a potentiating effect on the activity of ethionamide and uses thereof |
EP07803843A EP2044064A1 (fr) | 2006-07-04 | 2007-07-04 | Composes a effet potentialisateur de l'activite de l'ethionamide et leurs applications |
BRPI0714225-0A BRPI0714225A2 (pt) | 2006-07-04 | 2007-07-04 | compostos de efeito potencializador da atividade da etionamida e as respectivas aplicaÇÕes |
EA200970081A EA200970081A1 (ru) | 2006-07-04 | 2007-07-04 | Соединения, обладающие потенциирующим действием в отношении активности этионамида, и их применения |
AU2007271013A AU2007271013A1 (en) | 2006-07-04 | 2007-07-04 | Compounds having a potentiating effect on the activity of ethionamide and uses thereof |
PCT/FR2007/001138 WO2008003861A1 (fr) | 2006-07-04 | 2007-07-04 | Composes a effet potentialisateur de l'activite de l'ethionamide et leurs applications |
CA2656502A CA2656502C (fr) | 2006-07-04 | 2007-07-04 | Composes a effet potentialisateur de l'activite de l'ethionamide et leurs applications |
ZA200810703A ZA200810703B (en) | 2006-07-04 | 2008-12-19 | Compounds having a potentiating effect on the activity of ethionamide and uses thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0606088A FR2903405B1 (fr) | 2006-07-04 | 2006-07-04 | Composes a effet potentialisateur de l'activite de l'ethionamide et leurs applications |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2903405A1 FR2903405A1 (fr) | 2008-01-11 |
FR2903405B1 true FR2903405B1 (fr) | 2011-09-09 |
Family
ID=37775154
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR0606088A Expired - Fee Related FR2903405B1 (fr) | 2006-07-04 | 2006-07-04 | Composes a effet potentialisateur de l'activite de l'ethionamide et leurs applications |
Country Status (13)
Country | Link |
---|---|
US (1) | US8338599B2 (fr) |
EP (1) | EP2044064A1 (fr) |
JP (1) | JP2009541474A (fr) |
KR (1) | KR20090043506A (fr) |
CN (1) | CN101516876A (fr) |
AP (1) | AP2009004747A0 (fr) |
AU (1) | AU2007271013A1 (fr) |
BR (1) | BRPI0714225A2 (fr) |
CA (1) | CA2656502C (fr) |
EA (1) | EA200970081A1 (fr) |
FR (1) | FR2903405B1 (fr) |
WO (1) | WO2008003861A1 (fr) |
ZA (1) | ZA200810703B (fr) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2234643B1 (fr) | 2007-12-21 | 2013-01-09 | ETH Zurich | Composition pour le traitement de la tuberculose |
GB0813740D0 (en) * | 2008-07-28 | 2008-09-03 | Angeletti P Ist Richerche Biologica | Therapeutic compounds |
CN102458393B (zh) | 2009-06-25 | 2014-08-20 | 生物验证系统股份公司 | 治疗肺结核的组合物 |
GB0916608D0 (en) * | 2009-09-22 | 2009-11-04 | Angeletti P Ist Richerche Bio | Therapeutic compounds |
WO2012040170A2 (fr) * | 2010-09-20 | 2012-03-29 | University Of Virginia Patent Foundation | Compositions et méthodes de traitement de la tuberculose |
WO2013060744A2 (fr) | 2011-10-25 | 2013-05-02 | Universite De Droit Et De La Sante De Lille 2 | Composés présentant une activité d'inhibition d'ethr, utilisation desdits composés en tant que médicaments, composition pharmaceutique et produit contenant lesdits composés |
ES2632237T3 (es) | 2012-02-02 | 2017-09-12 | Idorsia Pharmaceuticals Ltd | Compuestos de 4-(benzoimidazol-2-il)-tiazol y derivados aza relacionados |
FR3000065A1 (fr) | 2012-12-21 | 2014-06-27 | Univ Lille Ii Droit & Sante | Composes bicycliques ayant une activite potentialisatrice de l'activite d'un antibiotique actif contre les mycobacteries-composition et produit pharmaceutiques comprenant de tels composes |
FR3000064A1 (fr) | 2012-12-21 | 2014-06-27 | Univ Lille Ii Droit & Sante | Composes de type spiroisoxazoline ayant une activite potentialisatrice de l'activite d'un antibiotique-composition et produit pharmaceutiques comprenant de tels composes |
TR201807959T4 (tr) | 2013-07-22 | 2018-06-21 | Idorsia Pharmaceuticals Ltd | 1-(Piperazın-1-il)-2- ([1,2,4] triazol-1-il)-etanon türevleri. |
AR099789A1 (es) | 2014-03-24 | 2016-08-17 | Actelion Pharmaceuticals Ltd | Derivados de 8-(piperazin-1-il)-1,2,3,4-tetrahidro-isoquinolina |
ES2709985T3 (es) | 2015-01-15 | 2019-04-22 | Idorsia Pharmaceuticals Ltd | Derivados de hidroxialquil-piperazina como moduladores del receptor CXCR3 |
AR103399A1 (es) | 2015-01-15 | 2017-05-10 | Actelion Pharmaceuticals Ltd | Derivados de (r)-2-metil-piperazina como moduladores del receptor cxcr3 |
KR102657861B1 (ko) * | 2017-08-16 | 2024-04-17 | 글락소스미스클라인 인털렉츄얼 프로퍼티 디벨로프먼트 리미티드 | 신규 화합물 |
BR112020004356A2 (pt) * | 2017-09-08 | 2020-12-01 | Pi Industries Ltd. | novos compostos heterocíclicos fungicidas |
CN108558858A (zh) * | 2018-05-23 | 2018-09-21 | 成都师范学院 | 硝基呋喃类抗结核化合物 |
AU2019387370A1 (en) | 2018-11-30 | 2021-06-10 | Nuvation Bio Inc. | Pyrrole and pyrazole compounds and methods of use thereof |
JP2023538199A (ja) * | 2020-06-23 | 2023-09-07 | ナンキン イムノファージ バイオテック カンパニー リミテッド | 化合物およびmif阻害剤としての用途 |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2275458A1 (fr) * | 1974-06-21 | 1976-01-16 | Aries Robert | Analogues de la rifampicine portant un noyau oxadiazole |
US6107313A (en) * | 1998-10-02 | 2000-08-22 | Combichem, Inc. | Dopamine receptor antagonists |
WO2001002375A1 (fr) * | 1999-07-01 | 2001-01-11 | Chemrx Advanced Technologies, Inc. | Synthese d'oxadiazoles |
US20010049373A1 (en) * | 2000-01-28 | 2001-12-06 | Chalquest Richard R. | Materials and methods for killing nematodes and nematode eggs |
JP4901102B2 (ja) * | 2002-05-03 | 2012-03-21 | エクセリクシス, インク. | プロテインキナーゼモジュレーターおよびその使用方法 |
US7074809B2 (en) * | 2002-08-09 | 2006-07-11 | Astrazeneca Ab | Compounds |
GB0325956D0 (en) * | 2003-11-06 | 2003-12-10 | Addex Pharmaceuticals Sa | Novel compounds |
CN1898235A (zh) * | 2003-12-24 | 2007-01-17 | 普罗西迪恩有限公司 | 作为gpcr受体激动剂的杂环衍生物 |
EP1604989A1 (fr) * | 2004-06-08 | 2005-12-14 | Santhera Pharmaceuticals (Deutschland) Aktiengesellschaft | Inhibiteurs de DPP-IV |
AU2005290081B2 (en) * | 2004-08-23 | 2010-12-02 | Merck Sharp & Dohme Corp. | Inhibitors of Akt activity |
TW200633990A (en) * | 2004-11-18 | 2006-10-01 | Takeda Pharmaceuticals Co | Amide compound |
WO2006060424A2 (fr) * | 2004-12-01 | 2006-06-08 | Kalypsys, Inc. | Inhibiteurs de la dimerisation de l'oxyde nitrique synthase inductible |
AU2005316826A1 (en) * | 2004-12-15 | 2006-06-22 | Merck Sharp & Dohme Corp. | Inhibitors of Akt activity |
EP1838706A1 (fr) * | 2004-12-24 | 2007-10-03 | Prosidion Limited | Agonistes du récepteur couplé aux protéines g |
-
2006
- 2006-07-04 FR FR0606088A patent/FR2903405B1/fr not_active Expired - Fee Related
-
2007
- 2007-07-04 CA CA2656502A patent/CA2656502C/fr not_active Expired - Fee Related
- 2007-07-04 JP JP2009517335A patent/JP2009541474A/ja active Pending
- 2007-07-04 KR KR1020097002316A patent/KR20090043506A/ko not_active Application Discontinuation
- 2007-07-04 BR BRPI0714225-0A patent/BRPI0714225A2/pt active Search and Examination
- 2007-07-04 WO PCT/FR2007/001138 patent/WO2008003861A1/fr active Application Filing
- 2007-07-04 EA EA200970081A patent/EA200970081A1/ru unknown
- 2007-07-04 CN CNA2007800326714A patent/CN101516876A/zh active Pending
- 2007-07-04 US US12/306,333 patent/US8338599B2/en not_active Expired - Fee Related
- 2007-07-04 EP EP07803843A patent/EP2044064A1/fr not_active Withdrawn
- 2007-07-04 AU AU2007271013A patent/AU2007271013A1/en not_active Abandoned
- 2007-07-04 AP AP2009004747A patent/AP2009004747A0/xx unknown
-
2008
- 2008-12-19 ZA ZA200810703A patent/ZA200810703B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
WO2008003861A1 (fr) | 2008-01-10 |
AU2007271013A1 (en) | 2008-01-10 |
EP2044064A1 (fr) | 2009-04-08 |
US20110136823A1 (en) | 2011-06-09 |
AP2009004747A0 (en) | 2009-02-28 |
CA2656502A1 (fr) | 2008-01-10 |
FR2903405A1 (fr) | 2008-01-11 |
EA200970081A1 (ru) | 2009-06-30 |
JP2009541474A (ja) | 2009-11-26 |
CN101516876A (zh) | 2009-08-26 |
US8338599B2 (en) | 2012-12-25 |
BRPI0714225A2 (pt) | 2013-01-29 |
CA2656502C (fr) | 2017-06-13 |
ZA200810703B (en) | 2009-10-28 |
KR20090043506A (ko) | 2009-05-06 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PLFP | Fee payment |
Year of fee payment: 10 |
|
PLFP | Fee payment |
Year of fee payment: 11 |
|
PLFP | Fee payment |
Year of fee payment: 12 |
|
PLFP | Fee payment |
Year of fee payment: 13 |
|
ST | Notification of lapse |
Effective date: 20200306 |