FR2904315B1 - Composes pyridaziniques et pyrroliques, procedes d'obtention et applications - Google Patents

Composes pyridaziniques et pyrroliques, procedes d'obtention et applications

Info

Publication number
FR2904315B1
FR2904315B1 FR0606842A FR0606842A FR2904315B1 FR 2904315 B1 FR2904315 B1 FR 2904315B1 FR 0606842 A FR0606842 A FR 0606842A FR 0606842 A FR0606842 A FR 0606842A FR 2904315 B1 FR2904315 B1 FR 2904315B1
Authority
FR
France
Prior art keywords
pyridazinic
obtaining
applications
methods
pyrrolic compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0606842A
Other languages
English (en)
Other versions
FR2904315A1 (fr
Inventor
Didier Max Dubreuil
Muriel Genevieve Pipelier
Jean Paul Pradere
Hicham Bakkali
Patrice Lepape
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre National de la Recherche Scientifique CNRS
Original Assignee
Centre National de la Recherche Scientifique CNRS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre National de la Recherche Scientifique CNRS filed Critical Centre National de la Recherche Scientifique CNRS
Priority to FR0606842A priority Critical patent/FR2904315B1/fr
Priority to CA002658624A priority patent/CA2658624A1/fr
Priority to US12/309,585 priority patent/US9034873B2/en
Priority to EP07823344A priority patent/EP2069345A2/fr
Priority to JP2009521300A priority patent/JP5564252B2/ja
Priority to PCT/FR2007/001287 priority patent/WO2008012440A2/fr
Publication of FR2904315A1 publication Critical patent/FR2904315A1/fr
Application granted granted Critical
Publication of FR2904315B1 publication Critical patent/FR2904315B1/fr
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/55—Acids; Esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/22—Tin compounds
    • C07F7/2208—Compounds having tin linked only to carbon, hydrogen and/or halogen
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B57/00—Other synthetic dyes of known constitution
    • C09B57/10—Metal complexes of organic compounds not being dyes in uncomplexed form

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Electrolytic Production Of Non-Metals, Compounds, Apparatuses Therefor (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FR0606842A 2006-07-26 2006-07-26 Composes pyridaziniques et pyrroliques, procedes d'obtention et applications Expired - Fee Related FR2904315B1 (fr)

Priority Applications (6)

Application Number Priority Date Filing Date Title
FR0606842A FR2904315B1 (fr) 2006-07-26 2006-07-26 Composes pyridaziniques et pyrroliques, procedes d'obtention et applications
CA002658624A CA2658624A1 (fr) 2006-07-26 2007-07-26 Composes pyridaziniques et pyrroliques, procedes d'obtention et applications
US12/309,585 US9034873B2 (en) 2006-07-26 2007-07-26 Pyridazine and pyrrole compounds, processes for obtaining them and uses
EP07823344A EP2069345A2 (fr) 2006-07-26 2007-07-26 Composes pyridaziniques et pyrroliques, procedes d'obtention et applications
JP2009521300A JP5564252B2 (ja) 2006-07-26 2007-07-26 ピリダジンおよびピロール化合物、それらを得るための方法および使用
PCT/FR2007/001287 WO2008012440A2 (fr) 2006-07-26 2007-07-26 Composes pyridaziniques et pyrroliques, procedes d'obtention et applications

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0606842A FR2904315B1 (fr) 2006-07-26 2006-07-26 Composes pyridaziniques et pyrroliques, procedes d'obtention et applications

Publications (2)

Publication Number Publication Date
FR2904315A1 FR2904315A1 (fr) 2008-02-01
FR2904315B1 true FR2904315B1 (fr) 2012-12-14

Family

ID=37763892

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0606842A Expired - Fee Related FR2904315B1 (fr) 2006-07-26 2006-07-26 Composes pyridaziniques et pyrroliques, procedes d'obtention et applications

Country Status (6)

Country Link
US (1) US9034873B2 (fr)
EP (1) EP2069345A2 (fr)
JP (1) JP5564252B2 (fr)
CA (1) CA2658624A1 (fr)
FR (1) FR2904315B1 (fr)
WO (1) WO2008012440A2 (fr)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2186810A1 (fr) 2008-10-31 2010-05-19 Institut Curie Dérivés de poly-hétéroaryle pour le traitement de cancer
CA2750252A1 (fr) 2009-01-28 2010-08-05 Smartcells, Inc. Conjugues synthetiques et leurs utilisations
US8846103B2 (en) 2009-01-28 2014-09-30 Smartcells, Inc. Exogenously triggered controlled release materials and uses thereof
WO2010088294A1 (fr) 2009-01-28 2010-08-05 Smartcells, Inc. Systèmes à base de conjugués pour administration contrôlée de médicaments
CA2750269A1 (fr) 2009-01-28 2010-08-05 Smartcells, Inc. Conjugues d'insuline cristalline
US8569231B2 (en) 2009-03-20 2013-10-29 Smartcells, Inc. Soluble non-depot insulin conjugates and uses thereof
AU2010226243A1 (en) 2009-03-20 2011-09-22 Smartcells, Inc. Terminally-functionalized conjugates and uses thereof
KR20120102649A (ko) 2009-10-30 2012-09-18 막스-플랑크-게젤샤프트 츄어 푀르더룽 데어 비쎈샤프텐 에.파우. 질소 함유 방향족 화합물 및 금속 착체
JP2013535467A (ja) 2010-07-28 2013-09-12 スマートセルズ・インコーポレイテツド 組換えにより発現されたインスリンポリペプチドおよびその使用
EP2598170A4 (fr) 2010-07-28 2016-07-06 Smartcells Inc Conjugués médicaments-ligands, leur synthèse et intermédiaires correspondants
JP2013541500A (ja) 2010-07-28 2013-11-14 スマートセルズ・インコーポレイテツド 組換えレクチン、結合部位修飾レクチンおよびそれらの用途
JP2014156402A (ja) * 2011-05-27 2014-08-28 Nippon Soda Co Ltd ビピリジン化合物および殺菌剤
WO2013033018A2 (fr) 2011-08-30 2013-03-07 Drexel University Complexes de dihydroxybipyridine de ruthénium et d'iridium destinés à l'oxydation de l'eau et à l'hydrogénation
WO2014164200A1 (fr) 2013-03-13 2014-10-09 Avon Products, Inc Inhibiteurs de la tyrosinase
WO2014158943A1 (fr) * 2013-03-13 2014-10-02 Avon Products, Inc Inhibiteurs de tyrosinase
WO2014164195A1 (fr) 2013-03-13 2014-10-09 Avon Products, Inc Inhibiteurs de tyrosinase
AU2014329567B2 (en) 2013-10-04 2019-07-25 Merck Sharp & Dohme Corp. Glucose-responsive insulin conjugates
US10130625B2 (en) 2014-07-22 2018-11-20 University Of Maryland, College Park Linked diaryl compounds with anticancer properties and methods of using the same
JP7063231B2 (ja) * 2018-10-26 2022-05-09 住友化学株式会社 ジピリダジニルエーテル化合物及びその用途
CN110437206B (zh) * 2019-03-13 2022-06-10 上海大学 吡啶-吡咯交替的分子折叠体及其制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3889065B2 (ja) * 1994-03-15 2007-03-07 株式会社東芝 有機非線形光学材料
DE10123586A1 (de) * 2001-05-08 2002-11-28 Schering Ag 3,5-Diamino-1,2,4-triazole als Kinase Inhibitoren

Also Published As

Publication number Publication date
US9034873B2 (en) 2015-05-19
CA2658624A1 (fr) 2008-01-31
WO2008012440A3 (fr) 2008-05-29
JP5564252B2 (ja) 2014-07-30
JP2009544671A (ja) 2009-12-17
EP2069345A2 (fr) 2009-06-17
FR2904315A1 (fr) 2008-02-01
WO2008012440A2 (fr) 2008-01-31
US20100298562A1 (en) 2010-11-25

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Effective date: 20160331