JP5065908B2 - Ｇタンパク質結合受容体作動薬 - Google Patents

Ｇタンパク質結合受容体作動薬 Download PDF

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Publication number
JP5065908B2
JP5065908B2 JP2007547682A JP2007547682A JP5065908B2 JP 5065908 B2 JP5065908 B2 JP 5065908B2 JP 2007547682 A JP2007547682 A JP 2007547682A JP 2007547682 A JP2007547682 A JP 2007547682A JP 5065908 B2 JP5065908 B2 JP 5065908B2
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JP
Japan
Prior art keywords
oxadiazol
pyridin
ylmethyl
piperidine
carboxylic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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JP2007547682A
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English (en)
Japanese (ja)
Other versions
JP2008525417A (ja
JP2008525417A5 (enExample
Inventor
マシュー・コリン・ソーア・ファイフ
ジェラード・ヒュー・トーマス
リサ・サラ・バートラム
スチュアート・エドワード・ブラッドリー
ウィリアム・ガトレル
クリステル・マリー・ラサミソン
ビラスベン・カンジ・シャー
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Prosidion Ltd
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Prosidion Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0428221A external-priority patent/GB0428221D0/en
Priority claimed from GB0513256A external-priority patent/GB0513256D0/en
Application filed by Prosidion Ltd filed Critical Prosidion Ltd
Publication of JP2008525417A publication Critical patent/JP2008525417A/ja
Publication of JP2008525417A5 publication Critical patent/JP2008525417A5/ja
Application granted granted Critical
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Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
JP2007547682A 2004-12-24 2005-12-23 Ｇタンパク質結合受容体作動薬 Expired - Fee Related JP5065908B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB0428221A GB0428221D0 (en) 2004-12-24 2004-12-24 Compounds
GB0428221.6 2004-12-24
GB0513256A GB0513256D0 (en) 2005-06-30 2005-06-30 Compounds
GB0513256.8 2005-06-30
PCT/GB2005/050265 WO2006067532A1 (en) 2004-12-24 2005-12-23 G-protein coupled receptor agonists

Publications (3)

Publication Number Publication Date
JP2008525417A JP2008525417A (ja) 2008-07-17
JP2008525417A5 JP2008525417A5 (enExample) 2008-12-11
JP5065908B2 true JP5065908B2 (ja) 2012-11-07

Family

ID=36097288

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007547682A Expired - Fee Related JP5065908B2 (ja) 2004-12-24 2005-12-23 Ｇタンパク質結合受容体作動薬

Country Status (4)

Country Link
US (1) US8193359B2 (enExample)
EP (1) EP1838706A1 (enExample)
JP (1) JP5065908B2 (enExample)
WO (1) WO2006067532A1 (enExample)

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