|
US2750393A
(en)
*
|
1954-12-01 |
1956-06-12 |
Sterling Drug Inc |
Iodinated 5-henzamidotetrazoles and preparation thereof
|
|
US2967194A
(en)
*
|
1958-05-15 |
1961-01-03 |
Pennsalt Chemicals Corp |
4-trifluoromethylsalicylamides
|
|
FR1526074A
(fr)
|
1967-03-22 |
1968-05-24 |
Rech S Ind S O R I Soc D |
Méthoxy-phényl-amino-2-thiazoles, leurs amides et leurs procédés de préparation
|
|
GB1352415A
(en)
|
1970-05-03 |
1974-05-08 |
Boots Co Ltd |
Esters of substituted nicotine acids
|
|
FR2088019A1
(en)
|
1970-05-08 |
1972-01-07 |
Rabot Ets David |
Esters of 2 and 6-substituted nicotinic acids - with vasomotor active
|
|
CS173097B1
(OSRAM)
|
1972-12-01 |
1977-02-28 |
|
|
|
GB1400540A
(en)
|
1972-12-06 |
1975-07-16 |
Smith Kline French Lab |
Salicylamides and compositions thereof
|
|
US4009174A
(en)
*
|
1972-12-08 |
1977-02-22 |
The Boots Company Limited |
Esters of substituted nicotinic acids
|
|
GB1437800A
(en)
*
|
1973-08-08 |
1976-06-03 |
Phavic Sprl |
Derivatives of 2-benzamido-5-nitro-thiazoles
|
|
GB1561350A
(en)
|
1976-11-05 |
1980-02-20 |
May & Baker Ltd |
Benzamide derivatives
|
|
FR2344284A1
(fr)
*
|
1976-03-17 |
1977-10-14 |
Cerm Cent Europ Rech Mauvernay |
Nouveaux composes tricycliques a cycle furannique et leur application comme antidepresseurs
|
|
GB1588242A
(en)
|
1977-10-28 |
1981-04-23 |
May & Baker Ltd |
N-(tetrazol-5-yl)-salicylamide derivatives
|
|
US4474792A
(en)
*
|
1979-06-18 |
1984-10-02 |
Riker Laboratories, Inc. |
N-Tetrazolyl benzamides and anti-allergic use thereof
|
|
FR2493848B2
(fr)
*
|
1980-11-07 |
1986-05-16 |
Delalande Sa |
Nouveaux derives des nor-tropane et granatane, leur procede de preparation et leur application en therapeutique
|
|
JPS59139357A
(ja)
*
|
1983-01-28 |
1984-08-10 |
Torii Yakuhin Kk |
アミジン誘導体
|
|
JPS62142168A
(ja)
|
1985-10-16 |
1987-06-25 |
Mitsubishi Chem Ind Ltd |
チアゾ−ル誘導体及びそれを有効成分とするロイコトリエンきつ抗剤
|
|
CA1327358C
(en)
|
1987-11-17 |
1994-03-01 |
Morio Fujiu |
Fluoro cytidine derivatives
|
|
JP2852659B2
(ja)
|
1988-03-03 |
1999-02-03 |
富山化学工業株式会社 |
ピペラジン誘導体およびその塩
|
|
DE3822449A1
(de)
|
1988-07-02 |
1990-01-04 |
Henkel Kgaa |
Oxidationshaarfaerbemittel mit neuen kupplern
|
|
US5466715A
(en)
*
|
1991-12-31 |
1995-11-14 |
Sterling Winthrop Inc. |
3,4-disubstituted phenols-immunomodulating agents
|
|
US5258407A
(en)
*
|
1991-12-31 |
1993-11-02 |
Sterling Winthrop Inc. |
3,4-disubstituted phenols-immunomodulating agents
|
|
US5273986A
(en)
*
|
1992-07-02 |
1993-12-28 |
Hoffmann-La Roche Inc. |
Cycloalkylthiazoles
|
|
EP0619116A3
(en)
|
1993-04-05 |
1994-11-23 |
Hoechst Japan |
Use of synthetic retinoids for osteopathy.
|
|
GB9307527D0
(en)
|
1993-04-13 |
1993-06-02 |
Fujisawa Pharmaceutical Co |
New venzamide derivatives,processes for the preparation thereof and pharmaceutical composition comprising the same
|
|
US5661153A
(en)
*
|
1994-07-19 |
1997-08-26 |
Japan Energy Corporation |
1-arylpyrimidine derivatives and pharmaceutical use thereof
|
|
US5510478A
(en)
*
|
1994-11-30 |
1996-04-23 |
American Home Products Corporation |
2-arylamidothiazole derivatives with CNS activity
|
|
US5672750A
(en)
*
|
1994-12-16 |
1997-09-30 |
Eastman Chemical Company |
Preparation of aromatic amides from carbon monoxide, an amine and an aromatic chloride
|
|
US5849735A
(en)
*
|
1995-01-17 |
1998-12-15 |
American Cyanamid Company |
Tricyclic benzazepine vasopressin antagonists
|
|
US5712270A
(en)
*
|
1995-11-06 |
1998-01-27 |
American Home Products Corporation |
2-arylamidothiazole derivatives with CNS activity
|
|
AUPO395396A0
(en)
*
|
1996-12-02 |
1997-01-02 |
Fujisawa Pharmaceutical Co., Ltd. |
Benzamide derivatives
|
|
FR2757852B1
(fr)
*
|
1996-12-31 |
1999-02-19 |
Cird Galderma |
Composes stilbeniques a groupement adamantyl, compositions les contenant et utilisations
|
|
EP1000932B9
(en)
|
1997-06-27 |
2005-12-28 |
Fujisawa Pharmaceutical Co., Ltd. |
Aromatic ring derivatives
|
|
EP0995742A4
(en)
|
1997-06-27 |
2004-08-25 |
Fujisawa Pharmaceutical Co |
SULPHONAMIDE COMPOUNDS AND THEIR MEDICAL USE
|
|
US6613942B1
(en)
*
|
1997-07-01 |
2003-09-02 |
Novo Nordisk A/S |
Glucagon antagonists/inverse agonists
|
|
US6114483A
(en)
|
1997-08-27 |
2000-09-05 |
E. I. Du Pont De Nemours And Company |
Polymerization of olefins
|
|
CA2309331A1
(en)
|
1997-11-12 |
1999-05-20 |
Institute Of Medicinal Molecular Design, Inc. |
Agent acting on retinoid receptor
|
|
GB9725298D0
(en)
|
1997-11-28 |
1998-01-28 |
Zeneca Ltd |
Insecticidal thiazole derivatives
|
|
ES2317688T3
(es)
*
|
1998-01-29 |
2009-04-16 |
Amgen Inc. |
Moduladores ppar-gamma.
|
|
DE19816780A1
(de)
|
1998-04-16 |
1999-10-21 |
Bayer Ag |
Substituierte 2-Oxo-alkansäure-[2-(indol-3-yl)-ethyl]amide
|
|
GB9811969D0
(en)
*
|
1998-06-03 |
1998-07-29 |
Celltech Therapeutics Ltd |
Chemical compounds
|
|
US6197798B1
(en)
*
|
1998-07-21 |
2001-03-06 |
Novartis Ag |
Amino-benzocycloalkane derivatives
|
|
JP4191825B2
(ja)
|
1998-09-10 |
2008-12-03 |
あすか製薬株式会社 |
５−アミノイソキサゾール誘導体
|
|
US6320050B1
(en)
*
|
1999-03-29 |
2001-11-20 |
Hoffmann-La Roche Inc. |
Heteroaromatic glucokinase activators
|
|
RU2242469C2
(ru)
*
|
1999-03-29 |
2004-12-20 |
Ф.Хоффманн-Ля Рош Аг |
Активаторы глюкокиназы
|
|
SI1169312T1
(en)
|
1999-03-29 |
2005-02-28 |
F. Hoffmann-La Roche Ag |
Glucokinase activators
|
|
US6610846B1
(en)
*
|
1999-03-29 |
2003-08-26 |
Hoffman-La Roche Inc. |
Heteroaromatic glucokinase activators
|
|
AU1917201A
(en)
*
|
1999-11-18 |
2001-05-30 |
Centaur Pharmaceuticals, Inc. |
Amide therapeutics and methods for treating inflammatory bowel disease
|
|
US6353111B1
(en)
|
1999-12-15 |
2002-03-05 |
Hoffmann-La Roche Inc. |
Trans olefinic glucokinase activators
|
|
CA2401778C
(en)
*
|
2000-02-29 |
2010-12-21 |
Cor Therapeutics, Inc. |
Benzamides and related inhibitors of factor xa
|
|
EP1132381A1
(en)
|
2000-03-08 |
2001-09-12 |
Cermol S.A. |
Ester derivatives of dimethylpropionic acid and pharmaceutical compositions containing them
|
|
US6534651B2
(en)
*
|
2000-04-06 |
2003-03-18 |
Inotek Pharmaceuticals Corp. |
7-Substituted isoindolinone inhibitors of inflammation and reperfusion injury and methods of use thereof
|
|
ES2233660T3
(es)
*
|
2000-05-03 |
2005-06-16 |
F. Hoffmann-La Roche Ag |
Activadores de glucokinasa alquinil fenil heteroaromaticos.
|
|
AU6837701A
(en)
*
|
2000-06-13 |
2001-12-24 |
American Home Prod |
Analgesic and anti-inflammatory compositions containing cox-2 inhibitors
|
|
MXPA03003572A
(es)
|
2000-11-22 |
2003-07-14 |
Yamanouchi Pharma Co Ltd |
Derivados de benceno sustituidos o sales de los mismos.
|
|
DK1341774T3
(da)
*
|
2000-12-06 |
2006-06-12 |
Hoffmann La Roche |
Kondenserede heteroaromatiske glucokinase-aktivatorer
|
|
WO2002051397A1
(en)
|
2000-12-22 |
2002-07-04 |
Ishihara Sangyo Kaisha, Ltd. |
Aniline derivatives or salts thereof and cytokine production inhibitors containing the same
|
|
US20040077697A1
(en)
|
2001-02-02 |
2004-04-22 |
Hiroyuki Koshio |
2-Acylaminothiazole derivative or its salt
|
|
SE0102300D0
(sv)
*
|
2001-06-26 |
2001-06-26 |
Astrazeneca Ab |
Compounds
|
|
SE0102299D0
(sv)
*
|
2001-06-26 |
2001-06-26 |
Astrazeneca Ab |
Compounds
|
|
PL368129A1
(en)
|
2001-08-09 |
2005-03-21 |
Ono Pharmaceutical Co, Ltd. |
Carboxylic acid derivative compounds and drugs comprising these compounds as the active ingredient
|
|
SE0102764D0
(sv)
|
2001-08-17 |
2001-08-17 |
Astrazeneca Ab |
Compounds
|
|
EP1336607A1
(en)
|
2002-02-19 |
2003-08-20 |
Novo Nordisk A/S |
Amide derivatives as glucokinase activators
|
|
DE10161765A1
(de)
*
|
2001-12-15 |
2003-07-03 |
Bayer Cropscience Gmbh |
Substituierte Phenylderivate
|
|
US6911545B2
(en)
|
2001-12-19 |
2005-06-28 |
Hoffman-La Roche Inc. |
Crystals of glucokinase and methods of growing them
|
|
EP1458382A1
(en)
|
2001-12-21 |
2004-09-22 |
Novo Nordisk A/S |
Amide derivatives as gk activators
|
|
DE60328671D1
(de)
|
2002-03-26 |
2009-09-17 |
Banyu Pharma Co Ltd |
Neue aminobenzamidderivate
|
|
EA011297B1
(ru)
|
2002-04-26 |
2009-02-27 |
Ф. Хоффманн-Ля Рош Аг |
Замещённые фенилацетамиды и их применение в качестве активаторов глюкокиназы
|
|
CA2488642C
(en)
|
2002-06-27 |
2011-09-06 |
Dharma Rao Polisetti |
Aryl carbonyl derivatives as glucokinase activators
|
|
WO2004007472A1
(ja)
|
2002-07-10 |
2004-01-22 |
Ono Pharmaceutical Co., Ltd. |
Ｃｃｒ４アンタゴニストおよびその医薬用途
|
|
GB0226930D0
(en)
*
|
2002-11-19 |
2002-12-24 |
Astrazeneca Ab |
Chemical compounds
|
|
GB0226931D0
(en)
|
2002-11-19 |
2002-12-24 |
Astrazeneca Ab |
Chemical compounds
|
|
MXPA05009059A
(es)
|
2003-02-26 |
2005-10-19 |
Banyu Pharma Co Ltd |
Derivados de heteroarilcarbamoilbenceno.
|
|
EP2385040A1
(en)
|
2003-03-14 |
2011-11-09 |
ONO Pharmaceutical Co., Ltd. |
Nitrogen-containing heterocyclic derivatives and drugs containing the same as the active ingredient
|
|
US20050165031A1
(en)
|
2003-11-13 |
2005-07-28 |
Ambit Biosciences Corporation |
Urea derivatives as ABL modulators
|
|
GB0327760D0
(en)
*
|
2003-11-29 |
2003-12-31 |
Astrazeneca Ab |
Compounds
|
|
GB0327761D0
(en)
*
|
2003-11-29 |
2003-12-31 |
Astrazeneca Ab |
Compounds
|
|
GB0328178D0
(en)
*
|
2003-12-05 |
2004-01-07 |
Astrazeneca Ab |
Compounds
|
|
KR20060105872A
(ko)
|
2003-12-29 |
2006-10-11 |
반유 세이야꾸 가부시끼가이샤 |
신규한 2-헤테로아릴 치환된 벤즈이미다졸 유도체
|
|
JP2007523142A
(ja)
*
|
2004-02-18 |
2007-08-16 |
アストラゼネカ アクチボラグ |
ベンズアミド誘導体、およびグルコキナーゼ活性化物質としてのそれらの使用
|
|
AU2005214137B2
(en)
*
|
2004-02-18 |
2008-05-29 |
Astrazeneca Ab |
Compounds
|
|
TW200600086A
(en)
*
|
2004-06-05 |
2006-01-01 |
Astrazeneca Ab |
Chemical compound
|
|
WO2006030925A1
(ja)
|
2004-09-13 |
2006-03-23 |
Ono Pharmaceutical Co., Ltd. |
含窒素複素環誘導体およびそれらを有効成分とする薬剤
|
|
GB0423044D0
(en)
*
|
2004-10-16 |
2004-11-17 |
Astrazeneca Ab |
Compounds
|
|
GB0423043D0
(en)
*
|
2004-10-16 |
2004-11-17 |
Astrazeneca Ab |
Compounds
|
|
KR20070085371A
(ko)
*
|
2004-10-16 |
2007-08-27 |
아스트라제네카 아베 |
페녹시 벤즈아미드 화합물의 제조 방법
|
|
CA2605738C
(en)
|
2005-04-25 |
2013-10-01 |
Merck Patent Gesellschaft Mit Beschraenkter Haftung |
Novel azaheterocyclic compounds as kinase inhibitors
|
|
TW200714597A
(en)
*
|
2005-05-27 |
2007-04-16 |
Astrazeneca Ab |
Chemical compounds
|
|
KR101346902B1
(ko)
*
|
2005-07-09 |
2014-01-02 |
아스트라제네카 아베 |
당뇨병 치료에 있어 ｇｌｋ 활성화제로서 사용하기 위한헤테로아릴 벤즈아미드 유도체
|
|
US20080234273A1
(en)
*
|
2005-07-09 |
2008-09-25 |
Mckerrecher Darren |
Heteroaryl Benzamide Derivatives for Use as Glk Activators in the Treatment of Diabetes
|
|
US20090105263A1
(en)
*
|
2005-09-16 |
2009-04-23 |
Peter William Rodney Caulkett |
Heterobicyclic compounds as glucokinase activators
|
|
TW200738621A
(en)
*
|
2005-11-28 |
2007-10-16 |
Astrazeneca Ab |
Chemical process
|
|
US8003642B2
(en)
*
|
2006-03-10 |
2011-08-23 |
Ono Pharmaceutical Co., Ltd. |
Nitrogenated heterocyclic derivative, and pharmaceutical agent comprising the derivative as active ingredient
|
|
TW200825063A
(en)
*
|
2006-10-23 |
2008-06-16 |
Astrazeneca Ab |
Chemical compounds
|
|
CL2007003061A1
(es)
*
|
2006-10-26 |
2008-08-01 |
Astrazeneca Ab |
Compuestos derivados de 3,5-dioxi-benzamida; proceso de preparacion; composicion farmaceutica que comprende a dichos compuestos; y su uso para tratar una enfermedad mediada a traves de glk, tal como la diabetes tipo 2.
|
|
US20100094009A1
(en)
*
|
2006-12-21 |
2010-04-15 |
Mccabe James |
Novel crystalline compound useful as glk activator
|
|
WO2010015849A2
(en)
*
|
2008-08-04 |
2010-02-11 |
Astrazeneca Ab |
Therapeutic agents 414
|
|
GB0902406D0
(en)
*
|
2009-02-13 |
2009-04-01 |
Astrazeneca Ab |
Crystalline polymorphic form
|
|
GB0902434D0
(en)
*
|
2009-02-13 |
2009-04-01 |
Astrazeneca Ab |
Chemical process
|
|
AR076220A1
(es)
*
|
2009-04-09 |
2011-05-26 |
Astrazeneca Ab |
Derivados de pirazol [4,5 - e] pirimidina
|
|
AR076221A1
(es)
*
|
2009-04-09 |
2011-05-26 |
Astrazeneca Ab |
Derivado de pirazol [4,5-e] pirimidina y su uso para tratar diabetes y obesidad
|