JP2008295444A5 - - Google Patents

Download PDF

Info

Publication number
JP2008295444A5
JP2008295444A5 JP2007265917A JP2007265917A JP2008295444A5 JP 2008295444 A5 JP2008295444 A5 JP 2008295444A5 JP 2007265917 A JP2007265917 A JP 2007265917A JP 2007265917 A JP2007265917 A JP 2007265917A JP 2008295444 A5 JP2008295444 A5 JP 2008295444A5
Authority
JP
Japan
Prior art keywords
seq
primer
antisense
base
primer set
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2007265917A
Other languages
English (en)
Japanese (ja)
Other versions
JP4303303B2 (ja
JP2008295444A (ja
Filing date
Publication date
Priority claimed from CA 2598893 external-priority patent/CA2598893C/en
Application filed filed Critical
Priority to JP2007265917A priority Critical patent/JP4303303B2/ja
Priority to US12/100,595 priority patent/US7605131B2/en
Publication of JP2008295444A publication Critical patent/JP2008295444A/ja
Publication of JP2008295444A5 publication Critical patent/JP2008295444A5/ja
Application granted granted Critical
Publication of JP4303303B2 publication Critical patent/JP4303303B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2007265917A 2006-10-11 2007-10-11 Eml4−alk融合遺伝子 Active JP4303303B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2007265917A JP4303303B2 (ja) 2006-10-11 2007-10-11 Eml4−alk融合遺伝子
US12/100,595 US7605131B2 (en) 2006-10-11 2008-04-10 EML4-ALK fusion gene

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2006277718 2006-10-11
JP2007120670 2007-05-01
CA 2598893 CA2598893C (en) 2006-10-11 2007-08-24 Eml4-alk fusion gene
JP2007265917A JP4303303B2 (ja) 2006-10-11 2007-10-11 Eml4−alk融合遺伝子

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2009035918A Division JP5172736B2 (ja) 2006-10-11 2009-02-18 Eml4−alk融合遺伝子

Publications (3)

Publication Number Publication Date
JP2008295444A JP2008295444A (ja) 2008-12-11
JP2008295444A5 true JP2008295444A5 (enExample) 2009-02-12
JP4303303B2 JP4303303B2 (ja) 2009-07-29

Family

ID=39277176

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2007265917A Active JP4303303B2 (ja) 2006-10-11 2007-10-11 Eml4−alk融合遺伝子
JP2009035918A Active JP5172736B2 (ja) 2006-10-11 2009-02-18 Eml4−alk融合遺伝子

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2009035918A Active JP5172736B2 (ja) 2006-10-11 2009-02-18 Eml4−alk融合遺伝子

Country Status (7)

Country Link
US (7) US7728120B2 (enExample)
EP (1) EP2116553B1 (enExample)
JP (2) JP4303303B2 (enExample)
AT (1) ATE450547T1 (enExample)
CA (1) CA2598893C (enExample)
DE (1) DE602007003543D1 (enExample)
ES (2) ES2515170T3 (enExample)

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120208824A1 (en) 2006-01-20 2012-08-16 Cell Signaling Technology, Inc. ROS Kinase in Lung Cancer
US8168383B2 (en) 2006-04-14 2012-05-01 Cell Signaling Technology, Inc. Gene defects and mutant ALK kinase in human solid tumors
EP3266867A1 (en) * 2006-04-14 2018-01-10 Cell Signaling Technology, Inc. Gene defects and mutant alk kinase in human solid tumors
CA2598893C (en) * 2006-10-11 2012-04-10 Astellas Pharma Inc. Eml4-alk fusion gene
CN101466721B (zh) * 2007-04-13 2013-08-21 细胞信号技术公司 在人实体瘤中的基因缺损和突变体alk激酶
TWI389893B (zh) * 2007-07-06 2013-03-21 Astellas Pharma Inc 二(芳胺基)芳基化合物
AU2009215168A1 (en) * 2008-02-12 2009-08-20 Dana-Farber Cancer Institute Fish assay for EML4 and ALK fusion in lung cancer
JP2009219728A (ja) * 2008-03-18 2009-10-01 Daito Giken:Kk 遊技台
MX2010012703A (es) 2008-05-21 2010-12-21 Ariad Pharma Inc Derivados fosforosos como inhibidores de cinasa.
US9273077B2 (en) 2008-05-21 2016-03-01 Ariad Pharmaceuticals, Inc. Phosphorus derivatives as kinase inhibitors
CA2762108A1 (en) * 2009-05-15 2010-11-18 Insight Genetics, Inc. Methods and compositions relating to fusions of alk for diagnosing and treating cancer
JPWO2011043220A1 (ja) 2009-10-06 2013-03-04 富士レビオ株式会社 融合遺伝子の測定方法
US9175350B2 (en) * 2009-12-22 2015-11-03 Quest Diagnostics Investments Incorporated EML4-ALK translocations in lung cancer
EP2540822B1 (en) * 2010-02-22 2017-05-03 Fujirebio Inc. Method for identification of oncogene, method for establishment of cell capable of expressing oncogene, and method for screening for oncogene-targeting substance
US8383793B2 (en) 2010-04-15 2013-02-26 St. Jude Children's Research Hospital Methods and compositions for the diagnosis and treatment of cancer resistant to anaplastic lymphoma kinase (ALK) kinase inhibitors
TW201202703A (en) * 2010-04-16 2012-01-16 Response Genetics Inc Primers, probes, methods, and kits for the detection of EML4-ALK variants
WO2012019132A2 (en) 2010-08-06 2012-02-09 Cell Signaling Technology, Inc. Anaplastic lymphoma kinase in kidney cancer
BR112013003879B1 (pt) 2010-08-20 2020-12-22 Chugai Seiyaku Kabushiki Kaisha composição compreendendo compostos tetracíclicos e formulação oralmente administrável que a compreende
US8962245B2 (en) 2010-09-02 2015-02-24 Kurume University Method for producing circular DNA formed from single-molecule DNA
JP2014005206A (ja) * 2010-10-22 2014-01-16 Astellas Pharma Inc アリールアミノヘテロ環カルボキサミド化合物
JP5769952B2 (ja) * 2010-11-12 2015-08-26 株式会社Lsiメディエンス Eml4−alk融合遺伝子の高感度検出方法
WO2012075318A2 (en) * 2010-12-01 2012-06-07 Cell Signaling Technology, Inc. Fn1 and alk gene translocations in cancer and alk kinase expression in ovarian cancer
BR112013019643B1 (pt) * 2011-02-02 2022-04-19 Novartis Ag Uso de inibidores de álcali
US20140296181A1 (en) * 2011-04-07 2014-10-02 Coferon, Inc. Methods of modulating oncogenic fusion proteins
BR112013027734A2 (pt) 2011-05-04 2017-08-08 Ariad Pharma Inc compostos para a inibição de proliferação celular em cânceres impulsionados pelo egfr, método e composição farmacêutica
EP2752486B1 (en) 2011-08-31 2016-12-28 Kurume University Method for exclusive selection of circularized dna from monomolecular dna when circularizing dna molecules
DK2838998T3 (en) 2012-04-18 2018-01-15 Cell Signaling Technology Inc EGFR AND ROS1 IN CANCER
AU2013204563B2 (en) 2012-05-05 2016-05-19 Takeda Pharmaceutical Company Limited Compounds for inhibiting cell proliferation in EGFR-driven cancers
US9084456B1 (en) * 2012-05-28 2015-07-21 Jack Zemer Linkage for jewelry components
EP2892536B1 (en) 2012-09-06 2019-12-18 Epizyme, Inc. Method of treating leukemia
CA2894220A1 (en) * 2012-12-21 2014-06-26 Epizyme, Inc. Dot1l inhibitors for use in the treatment of leukemia
EP2958592A1 (en) 2013-02-22 2015-12-30 F. Hoffmann-La Roche AG Methods of treating cancer and preventing drug resistance
US9611283B1 (en) 2013-04-10 2017-04-04 Ariad Pharmaceuticals, Inc. Methods for inhibiting cell proliferation in ALK-driven cancers
JP6534930B2 (ja) 2013-07-26 2019-06-26 公益財団法人がん研究会 Ntrk3融合体の検出法
WO2015064620A1 (ja) * 2013-10-29 2015-05-07 公益財団法人がん研究会 新規融合体及びその検出法
WO2015064621A1 (ja) * 2013-10-29 2015-05-07 公益財団法人がん研究会 新規融合体及びその検出法
EP3098312B1 (en) 2014-01-24 2023-07-19 Japanese Foundation For Cancer Research Novel fusant and method for detecting same
CN106458967A (zh) 2014-04-25 2017-02-22 中外制药株式会社 四环化合物的新结晶
CN106456651A (zh) 2014-04-25 2017-02-22 中外制药株式会社 以高用量含有四环性化合物的制剂
TWI718102B (zh) 2014-08-08 2021-02-11 日商中外製藥股份有限公司 4環性化合物的非晶質體
US10597725B2 (en) * 2014-09-01 2020-03-24 Arkray, Inc. Primer reagent for amplifying ALK fusion gene, ALK fusion gene amplification reagent kit including the same, and ALK fusion gene amplification method and ALK fusion gene analysis method using the same
JP7015171B2 (ja) 2016-01-15 2022-02-02 公益財団法人がん研究会 新規融合体及びその検出法
JP6740172B2 (ja) * 2017-05-02 2020-08-12 セル・シグナリング・テクノロジー・インコーポレイテツド ヒト固形腫瘍における遺伝子欠失及び突然変異alkキナーゼ
US12473548B2 (en) * 2018-06-27 2025-11-18 City Of Hope Modification of small RNAs for therapeutic uses
EP3815688B1 (en) 2018-06-29 2023-12-06 Chugai Seiyaku Kabushiki Kaisha Pharmaceutical composition containing poorly-soluble basic medicine
JP7385191B2 (ja) * 2019-08-30 2023-11-22 学校法人同志社 Eml4-alk阻害ペプチドおよびこれを含む肺がん治療薬
JP2020156481A (ja) * 2020-04-06 2020-10-01 セル・シグナリング・テクノロジー・インコーポレイテツド ヒト固形腫瘍における遺伝子欠失及び突然変異alkキナーゼ
CN118159274A (zh) 2021-10-28 2024-06-07 中外制药株式会社 糖浆剂
TW202412771A (zh) 2022-07-04 2024-04-01 日商中外製藥股份有限公司 併用醫藥
CN119789871A (zh) 2022-08-30 2025-04-08 中外制药株式会社 并用药物

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2338210T3 (es) 1999-11-11 2010-05-05 Astellas Pharma Inc. Metaloproteasa novedosa que tiene actividad agrecanasa.
GB0305929D0 (en) 2003-03-14 2003-04-23 Novartis Ag Organic compounds
CA2532800C (en) 2003-07-23 2013-06-18 Exelixis, Inc. Anaplastic lymphoma kinase modulators and methods of use
BR122019017579B8 (pt) 2003-08-15 2021-07-27 Novartis Ag 2,4-pirimidinadiaminas, seus usos, combinação e composição farmacêutica
CA2559866A1 (en) 2004-03-31 2005-10-20 Exelixis, Inc. Anaplastic lymphoma kinase modulators and methods of use
CA2598893C (en) * 2006-10-11 2012-04-10 Astellas Pharma Inc. Eml4-alk fusion gene
CN101466721B (zh) * 2007-04-13 2013-08-21 细胞信号技术公司 在人实体瘤中的基因缺损和突变体alk激酶
TWI389893B (zh) 2007-07-06 2013-03-21 Astellas Pharma Inc 二(芳胺基)芳基化合物

Similar Documents

Publication Publication Date Title
JP2008295444A5 (enExample)
US12534754B2 (en) Attenuators
JP2019196400A5 (enExample)
US11293048B2 (en) Attenuators
JP2003524416A5 (enExample)
JP2017510244A5 (enExample)
JP2008532477A5 (enExample)
JP2008535489A5 (enExample)
JP2006512928A5 (enExample)
JP2008535509A5 (enExample)
JP2012514451A5 (enExample)
JP2007075118A5 (enExample)
JP2006518186A5 (enExample)
WO2006029184A3 (en) Genes useful for diagnosing and monitoring inflammation related disorders
JP2010035552A5 (enExample)
JP2005511023A5 (enExample)
JP4235645B2 (ja) 呼吸器疾患と関連した10種のバクテリアに特異的なプライマーセット及びプローブオリゴヌクレオチド
WO2009044085A3 (fr) Oligonucleotides, utilisation, methode de detection et kit permettant de diganostiquer la presence du gene e1 du virus de chikungunya
JP2017521654A5 (enExample)
JP2004523211A5 (enExample)
JP2004519219A5 (enExample)
KR101531296B1 (ko) Streptococcus iniae의 병원성 판별용 유전자 마커 및 펩티드핵산을 이용한 병원성 결정 마커 검사키트
JP4934679B2 (ja) 9種の呼吸器疾患と関連するバクテリア種を特異的に検出するためのプライマー、プローブ、マイクロアレイおよびその方法
JP2006501465A5 (enExample)
JP2007513601A5 (enExample)