|
US4235877A
(en)
|
1979-06-27 |
1980-11-25 |
Merck & Co., Inc. |
Liposome particle containing viral or bacterial antigenic subunit
|
|
US4372945A
(en)
|
1979-11-13 |
1983-02-08 |
Likhite Vilas V |
Antigen compounds
|
|
IL61904A
(en)
|
1981-01-13 |
1985-07-31 |
Yeda Res & Dev |
Synthetic vaccine against influenza virus infections comprising a synthetic peptide and process for producing same
|
|
US4769330A
(en)
|
1981-12-24 |
1988-09-06 |
Health Research, Incorporated |
Modified vaccinia virus and methods for making and using the same
|
|
US4603112A
(en)
|
1981-12-24 |
1986-07-29 |
Health Research, Incorporated |
Modified vaccinia virus
|
|
GB8508845D0
(en)
|
1985-04-04 |
1985-05-09 |
Hoffmann La Roche |
Vaccinia dna
|
|
US4777127A
(en)
|
1985-09-30 |
1988-10-11 |
Labsystems Oy |
Human retrovirus-related products and methods of diagnosing and treating conditions associated with said retrovirus
|
|
US4946778A
(en)
|
1987-09-21 |
1990-08-07 |
Genex Corporation |
Single polypeptide chain binding molecules
|
|
ATE111083T1
(de)
|
1986-10-22 |
1994-09-15 |
Abbott Lab |
Chemilumineszierende acridinium- und phenantridiniumsalze.
|
|
WO1989001973A2
(en)
|
1987-09-02 |
1989-03-09 |
Applied Biotechnology, Inc. |
Recombinant pox virus for immunization against tumor-associated antigens
|
|
US5006309A
(en)
|
1988-04-22 |
1991-04-09 |
Abbott Laboratories |
Immunoassay device with liquid transfer between wells by washing
|
|
US5089424A
(en)
|
1988-06-14 |
1992-02-18 |
Abbott Laboratories |
Method and apparatus for heterogeneous chemiluminescence assay
|
|
US5241070A
(en)
|
1988-09-26 |
1993-08-31 |
Ciba Corning Diagnostics Corp. |
Nucleophilic polysubstituted aryl acridinium esters and uses thereof
|
|
SE462454B
(sv)
|
1988-11-10 |
1990-06-25 |
Pharmacia Ab |
Maetyta foer anvaendning i biosensorer
|
|
US5063081A
(en)
|
1988-11-14 |
1991-11-05 |
I-Stat Corporation |
Method of manufacturing a plurality of uniform microfabricated sensing devices having an immobilized ligand receptor
|
|
US5210015A
(en)
|
1990-08-06 |
1993-05-11 |
Hoffman-La Roche Inc. |
Homogeneous assay system using the nuclease activity of a nucleic acid polymerase
|
|
CA2048302A1
(en)
|
1990-08-15 |
1992-02-16 |
Victoria P. Meucci |
Solubilization reagent for biological test samples
|
|
US5135875A
(en)
|
1990-08-15 |
1992-08-04 |
Abbott Laboratories |
Protein precipitation reagent
|
|
CA2069530A1
(en)
|
1991-06-03 |
1992-12-04 |
Cass J. Grandone |
Reagent pack for immunoassays
|
|
AU2402292A
(en)
|
1991-07-29 |
1993-03-02 |
Serex, Inc. |
Differential binding affinities and dissociation assays based thereon
|
|
CA2131727A1
(en)
|
1992-03-30 |
1993-10-14 |
Diana E. Clarisse |
Reagents and methods for the detection and quantification of thyroxine in fluid samples
|
|
US5352803A
(en)
|
1992-03-30 |
1994-10-04 |
Abbott Laboratories |
5(6)-methyl substituted fluorescein derivatives
|
|
US5605798A
(en)
|
1993-01-07 |
1997-02-25 |
Sequenom, Inc. |
DNA diagnostic based on mass spectrometry
|
|
US5538848A
(en)
|
1994-11-16 |
1996-07-23 |
Applied Biosystems Division, Perkin-Elmer Corp. |
Method for detecting nucleic acid amplification using self-quenching fluorescence probe
|
|
US6156495A
(en)
*
|
1994-02-14 |
2000-12-05 |
Abbott Laboratories |
Hepatitis GB virus recombinant proteins and uses thereof
|
|
US5981172A
(en)
*
|
1994-02-14 |
1999-11-09 |
Abbott Laboratories |
Non-A, non-B, non-C, non-D, non-E Hepatitis reagents and methods for their use
|
|
US5714330A
(en)
|
1994-04-04 |
1998-02-03 |
Lynx Therapeutics, Inc. |
DNA sequencing by stepwise ligation and cleavage
|
|
EP0777749B1
(en)
|
1994-08-19 |
2002-10-30 |
PE Corporation (NY) |
Coupled amplification and ligation method
|
|
US5695934A
(en)
|
1994-10-13 |
1997-12-09 |
Lynx Therapeutics, Inc. |
Massively parallel sequencing of sorted polynucleotides
|
|
WO1998029747A1
(en)
|
1994-11-23 |
1998-07-09 |
Abbott Laboratories |
Reagents and methods for detecting hepatitis gb virus antigen
|
|
US5750341A
(en)
|
1995-04-17 |
1998-05-12 |
Lynx Therapeutics, Inc. |
DNA sequencing by parallel oligonucleotide extensions
|
|
WO1996040930A1
(en)
|
1995-06-07 |
1996-12-19 |
Regents Of The University Of Minnesota |
Mutants of streptococcal toxin a and methods of use
|
|
JP3439221B2
(ja)
|
1995-12-18 |
2003-08-25 |
ワシントン ユニヴァーシティ |
蛍光共鳴エネルギー移動を利用する核酸分析方法
|
|
US5777324A
(en)
|
1996-09-19 |
1998-07-07 |
Sequenom, Inc. |
Method and apparatus for maldi analysis
|
|
GB9620209D0
(en)
|
1996-09-27 |
1996-11-13 |
Cemu Bioteknik Ab |
Method of sequencing DNA
|
|
GB9626815D0
(en)
|
1996-12-23 |
1997-02-12 |
Cemu Bioteknik Ab |
Method of sequencing DNA
|
|
US6969488B2
(en)
|
1998-05-22 |
2005-11-29 |
Solexa, Inc. |
System and apparatus for sequential processing of analytes
|
|
US5863736A
(en)
|
1997-05-23 |
1999-01-26 |
Becton, Dickinson And Company |
Method, apparatus and computer program products for determining quantities of nucleic acid sequences in samples
|
|
NZ516848A
(en)
|
1997-06-20 |
2004-03-26 |
Ciphergen Biosystems Inc |
Retentate chromatography apparatus with applications in biology and medicine
|
|
US6511803B1
(en)
|
1997-10-10 |
2003-01-28 |
President And Fellows Of Harvard College |
Replica amplification of nucleic acid arrays
|
|
AU737174B2
(en)
|
1997-10-10 |
2001-08-09 |
President & Fellows Of Harvard College |
Replica amplification of nucleic acid arrays
|
|
US6485944B1
(en)
|
1997-10-10 |
2002-11-26 |
President And Fellows Of Harvard College |
Replica amplification of nucleic acid arrays
|
|
CA2323638A1
(en)
|
1998-04-03 |
1999-10-14 |
Phylos, Inc. |
Addressable protein arrays
|
|
US6406921B1
(en)
|
1998-07-14 |
2002-06-18 |
Zyomyx, Incorporated |
Protein arrays for high-throughput screening
|
|
US6787308B2
(en)
|
1998-07-30 |
2004-09-07 |
Solexa Ltd. |
Arrayed biomolecules and their use in sequencing
|
|
AR021833A1
(es)
|
1998-09-30 |
2002-08-07 |
Applied Research Systems |
Metodos de amplificacion y secuenciacion de acido nucleico
|
|
WO2000056934A1
(en)
|
1999-03-24 |
2000-09-28 |
Packard Bioscience Company |
Continuous porous matrix arrays
|
|
EP1218543A2
(en)
|
1999-09-29 |
2002-07-03 |
Solexa Ltd. |
Polynucleotide sequencing
|
|
US6936702B2
(en)
|
2000-06-07 |
2005-08-30 |
Li-Cor, Inc. |
Charge-switch nucleotides
|
|
EP1975251A3
(en)
|
2000-07-07 |
2009-03-25 |
Visigen Biotechnologies, Inc. |
Real-time sequence determination
|
|
US20030027135A1
(en)
|
2001-03-02 |
2003-02-06 |
Ecker David J. |
Method for rapid detection and identification of bioagents
|
|
US7419821B2
(en)
|
2002-03-05 |
2008-09-02 |
I-Stat Corporation |
Apparatus and methods for analyte measurement and immunoassay
|
|
US20040018577A1
(en)
|
2002-07-29 |
2004-01-29 |
Emerson Campbell John Lewis |
Multiple hybrid immunoassay
|
|
US7244567B2
(en)
|
2003-01-29 |
2007-07-17 |
454 Life Sciences Corporation |
Double ended sequencing
|
|
US7682833B2
(en)
|
2003-09-10 |
2010-03-23 |
Abbott Point Of Care Inc. |
Immunoassay device with improved sample closure
|
|
US7723099B2
(en)
|
2003-09-10 |
2010-05-25 |
Abbott Point Of Care Inc. |
Immunoassay device with immuno-reference electrode
|
|
EP1790202A4
(en)
|
2004-09-17 |
2013-02-20 |
Pacific Biosciences California |
APPARATUS AND METHOD FOR ANALYZING MOLECULES
|
|
US7170050B2
(en)
|
2004-09-17 |
2007-01-30 |
Pacific Biosciences Of California, Inc. |
Apparatus and methods for optical analysis of molecules
|
|
EP2230315A1
(en)
|
2005-02-01 |
2010-09-22 |
AB Advanced Genetic Analysis Corporation |
Nucleic acid sequencing by performing successive cycles of duplex extension
|
|
US20070141598A1
(en)
|
2005-02-09 |
2007-06-21 |
Pacific Biosciences Of California, Inc. |
Nucleotide Compositions and Uses Thereof
|
|
US7805081B2
(en)
|
2005-08-11 |
2010-09-28 |
Pacific Biosciences Of California, Inc. |
Methods and systems for monitoring multiple optical signals from a single source
|
|
US7405281B2
(en)
|
2005-09-29 |
2008-07-29 |
Pacific Biosciences Of California, Inc. |
Fluorescent nucleotide analogs and uses therefor
|
|
US7763423B2
(en)
|
2005-09-30 |
2010-07-27 |
Pacific Biosciences Of California, Inc. |
Substrates having low density reactive groups for monitoring enzyme activity
|
|
CA2631248C
(en)
|
2005-11-28 |
2016-01-12 |
Pacific Biosciences Of California, Inc. |
Uniform surfaces for hybrid material substrates and methods for making and using same
|
|
US7998717B2
(en)
|
2005-12-02 |
2011-08-16 |
Pacific Biosciences Of California, Inc. |
Mitigation of photodamage in analytical reactions
|
|
AU2006331512B2
(en)
|
2005-12-22 |
2012-02-23 |
Pacific Biosciences Of California, Inc. |
Active surface coupled polymerases
|
|
EP3056575B1
(en)
|
2005-12-22 |
2017-10-11 |
Pacific Biosciences Of California, Inc. |
Polymerases for nucleotide analogue incorporation
|
|
US7995202B2
(en)
|
2006-02-13 |
2011-08-09 |
Pacific Biosciences Of California, Inc. |
Methods and systems for simultaneous real-time monitoring of optical signals from multiple sources
|
|
US7692783B2
(en)
|
2006-02-13 |
2010-04-06 |
Pacific Biosciences Of California |
Methods and systems for simultaneous real-time monitoring of optical signals from multiple sources
|
|
US7715001B2
(en)
|
2006-02-13 |
2010-05-11 |
Pacific Biosciences Of California, Inc. |
Methods and systems for simultaneous real-time monitoring of optical signals from multiple sources
|
|
US20080050747A1
(en)
|
2006-03-30 |
2008-02-28 |
Pacific Biosciences Of California, Inc. |
Articles having localized molecules disposed thereon and methods of producing and using same
|
|
US8975216B2
(en)
|
2006-03-30 |
2015-03-10 |
Pacific Biosciences Of California |
Articles having localized molecules disposed thereon and methods of producing same
|
|
US7563574B2
(en)
|
2006-03-31 |
2009-07-21 |
Pacific Biosciences Of California, Inc. |
Methods, systems and compositions for monitoring enzyme activity and applications thereof
|
|
WO2007149724A2
(en)
|
2006-06-12 |
2007-12-27 |
Pacific Biosciences Of California, Inc. |
Substrates for performing analytical reactions
|
|
AU2007260707A1
(en)
|
2006-06-16 |
2007-12-21 |
Pacific Biosciences Of California, Inc. |
Controlled initiation of primer extension
|
|
US7883855B2
(en)
|
2006-07-21 |
2011-02-08 |
Abbott Laboratories |
Immunosuppressant drug extraction reagent for immunoassays
|
|
EP3936857B1
(en)
|
2006-09-01 |
2023-06-21 |
Pacific Biosciences Of California, Inc. |
Substrates, systems and methods for analyzing materials
|
|
US20080080059A1
(en)
|
2006-09-28 |
2008-04-03 |
Pacific Biosciences Of California, Inc. |
Modular optical components and systems incorporating same
|
|
CA2666517A1
(en)
|
2006-10-23 |
2008-05-02 |
Pacific Biosciences Of California, Inc. |
Polymerase enzymes and reagents for enhanced nucleic acid sequencing
|
|
JP5622392B2
(ja)
|
2006-12-14 |
2014-11-12 |
ライフ テクノロジーズ コーポレーション |
大規模fetアレイを用いた分析物測定のための方法および装置
|
|
US8262900B2
(en)
|
2006-12-14 |
2012-09-11 |
Life Technologies Corporation |
Methods and apparatus for measuring analytes using large scale FET arrays
|
|
US8551704B2
(en)
|
2007-02-16 |
2013-10-08 |
Pacific Biosciences Of California, Inc. |
Controllable strand scission of mini circle DNA
|
|
US7906293B2
(en)
|
2007-04-09 |
2011-03-15 |
Abbott Laboratories |
Acridinium phenyl esters useful in the analysis of biological
|
|
CN102083998B
(zh)
|
2007-06-19 |
2016-08-03 |
斯特拉托斯基因公司 |
通过展开进行高通量核酸测序
|
|
US20100137143A1
(en)
|
2008-10-22 |
2010-06-03 |
Ion Torrent Systems Incorporated |
Methods and apparatus for measuring analytes
|
|
US20100301398A1
(en)
|
2009-05-29 |
2010-12-02 |
Ion Torrent Systems Incorporated |
Methods and apparatus for measuring analytes
|
|
WO2012075104A2
(en)
*
|
2010-11-30 |
2012-06-07 |
The Trustees Of Columbia University In The City Of New York |
Novel non-primate hepacivirus
|
|
US9002545B2
(en)
|
2011-01-07 |
2015-04-07 |
Wabtec Holding Corp. |
Data improvement system and method
|