JP2008517918A5 - - Google Patents
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- Publication number
- JP2008517918A5 JP2008517918A5 JP2007538033A JP2007538033A JP2008517918A5 JP 2008517918 A5 JP2008517918 A5 JP 2008517918A5 JP 2007538033 A JP2007538033 A JP 2007538033A JP 2007538033 A JP2007538033 A JP 2007538033A JP 2008517918 A5 JP2008517918 A5 JP 2008517918A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- immunogenic composition
- polypeptide
- staphylococcus epidermidis
- polynucleotide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 claims 54
- 230000002163 immunogen Effects 0.000 claims 33
- 229920001184 polypeptide Polymers 0.000 claims 24
- 102000004196 processed proteins & peptides Human genes 0.000 claims 24
- 108090000765 processed proteins & peptides Proteins 0.000 claims 24
- 241000191963 Staphylococcus epidermidis Species 0.000 claims 19
- 108091033319 polynucleotide Proteins 0.000 claims 17
- 239000002157 polynucleotide Substances 0.000 claims 17
- 102000040430 polynucleotide Human genes 0.000 claims 17
- 239000012634 fragment Substances 0.000 claims 11
- 239000002773 nucleotide Substances 0.000 claims 8
- 125000003729 nucleotide group Chemical group 0.000 claims 8
- 239000000523 sample Substances 0.000 claims 7
- 230000028993 immune response Effects 0.000 claims 5
- 238000000034 method Methods 0.000 claims 5
- 239000003795 chemical substances by application Substances 0.000 claims 4
- 238000001890 transfection Methods 0.000 claims 4
- 239000002671 adjuvant Substances 0.000 claims 3
- 125000003275 alpha amino acid group Chemical group 0.000 claims 3
- 239000000427 antigen Substances 0.000 claims 3
- 102000036639 antigens Human genes 0.000 claims 3
- 108091007433 antigens Proteins 0.000 claims 3
- 239000003937 drug carrier Substances 0.000 claims 3
- 230000014509 gene expression Effects 0.000 claims 3
- 238000009396 hybridization Methods 0.000 claims 3
- 239000013598 vector Substances 0.000 claims 3
- LEBVLXFERQHONN-UHFFFAOYSA-N 1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide Chemical compound CCCCN1CCCCC1C(=O)NC1=C(C)C=CC=C1C LEBVLXFERQHONN-UHFFFAOYSA-N 0.000 claims 2
- 241000283973 Oryctolagus cuniculus Species 0.000 claims 2
- 241000191967 Staphylococcus aureus Species 0.000 claims 2
- 150000001413 amino acids Chemical class 0.000 claims 2
- 239000012472 biological sample Substances 0.000 claims 2
- 229960003150 bupivacaine Drugs 0.000 claims 2
- 238000001514 detection method Methods 0.000 claims 2
- 230000004927 fusion Effects 0.000 claims 2
- 150000004676 glycans Chemical class 0.000 claims 2
- 230000001939 inductive effect Effects 0.000 claims 2
- 230000003472 neutralizing effect Effects 0.000 claims 2
- 239000013612 plasmid Substances 0.000 claims 2
- 229920001282 polysaccharide Polymers 0.000 claims 2
- 239000005017 polysaccharide Substances 0.000 claims 2
- 230000001105 regulatory effect Effects 0.000 claims 2
- 102000004506 Blood Proteins Human genes 0.000 claims 1
- 108010017384 Blood Proteins Proteins 0.000 claims 1
- 102000004895 Lipoproteins Human genes 0.000 claims 1
- 108090001030 Lipoproteins Proteins 0.000 claims 1
- 108091034117 Oligonucleotide Proteins 0.000 claims 1
- 230000009918 complex formation Effects 0.000 claims 1
- 239000013604 expression vector Substances 0.000 claims 1
- 210000002966 serum Anatomy 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US62078804P | 2004-10-21 | 2004-10-21 | |
| PCT/US2005/037746 WO2007001423A2 (en) | 2004-10-21 | 2005-10-19 | Immunogenic compositions of staphylococcus epidermidis polypeptide and polynucleotide antigens |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013021337A Division JP2013121981A (ja) | 2004-10-21 | 2013-02-06 | Staphylococcusepidermidisポリペプチド抗原の免疫原性組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008517918A JP2008517918A (ja) | 2008-05-29 |
| JP2008517918A5 true JP2008517918A5 (enExample) | 2008-10-02 |
Family
ID=37595601
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007538033A Pending JP2008517918A (ja) | 2004-10-21 | 2005-10-19 | Staphylococcusepidermidisポリペプチド抗原の免疫原性組成物 |
| JP2013021337A Pending JP2013121981A (ja) | 2004-10-21 | 2013-02-06 | Staphylococcusepidermidisポリペプチド抗原の免疫原性組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013021337A Pending JP2013121981A (ja) | 2004-10-21 | 2013-02-06 | Staphylococcusepidermidisポリペプチド抗原の免疫原性組成物 |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US8445000B2 (enExample) |
| EP (4) | EP2340848A3 (enExample) |
| JP (2) | JP2008517918A (enExample) |
| KR (1) | KR20070068455A (enExample) |
| CN (1) | CN101175508A (enExample) |
| AR (1) | AR051826A1 (enExample) |
| AU (1) | AU2005333603A1 (enExample) |
| BR (1) | BRPI0516974A (enExample) |
| CA (1) | CA2583121A1 (enExample) |
| IL (1) | IL182546A0 (enExample) |
| TW (1) | TW200619228A (enExample) |
| WO (1) | WO2007001423A2 (enExample) |
| ZA (1) | ZA200703274B (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2468803B (en) * | 2005-05-19 | 2011-01-19 | Exocyte Ltd | Screening methods for bacterial killing |
| WO2010119343A2 (en) * | 2009-04-14 | 2010-10-21 | Novartis Ag | Compositions for immunising against staphylococcus aureus |
| JP5395264B2 (ja) | 2009-06-22 | 2014-01-22 | ワイス・エルエルシー | 黄色ブドウ球菌(staphylococcusaureus)抗原の免疫原性組成物 |
| US20110200995A1 (en) * | 2009-09-04 | 2011-08-18 | Intelligent Medical Devices, Inc. | Optimized probes and primers and methods of using same for the detection, screening, isolation and sequencing of vancomycin resistance genes and vancomycin resistant enterococci |
| AU2012280904B2 (en) | 2011-07-06 | 2017-02-23 | Glaxosmithkline Biologicals S.A. | Cationic oil-in-water emulsions |
| US9655845B2 (en) | 2011-07-06 | 2017-05-23 | Glaxosmithkline Biologicals, S.A. | Oil-in-water emulsions that contain nucleic acids |
| WO2014033192A1 (en) * | 2012-08-31 | 2014-03-06 | Novartis Ag | Stabilised proteins for immunising against staphylococcus aureus |
| ES2769647T3 (es) * | 2014-03-26 | 2020-06-26 | Glaxosmithkline Biologicals Sa | Antígenos estafilocócicos mutantes |
| JP7181208B2 (ja) * | 2016-10-21 | 2022-11-30 | ソクプラ、サイエンシズ、エ、ジェニ、エス.イー.シー. | ワクチン構築物およびブドウ球菌感染症に対するその使用 |
| SG11202106340XA (en) * | 2019-01-30 | 2021-07-29 | Fujifilm Electronic Materials Usa Inc | Container and method of preparing the same |
| KR102627009B1 (ko) * | 2021-12-17 | 2024-01-19 | (주)메디톡스 | 피부 유해 세균에 대한 항세균 활성을 갖는 세균 균주, 및 이를 포함하는 약제학적 조성물 |
Family Cites Families (46)
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| ZA811368B (en) | 1980-03-24 | 1982-04-28 | Genentech Inc | Bacterial polypedtide expression employing tryptophan promoter-operator |
| US4837151A (en) | 1980-05-19 | 1989-06-06 | The Board Of Trustees Of The Leland Stanford Junior University, Stanford University | Live vaccines comprising two mutations and foreign antigen |
| US4554101A (en) | 1981-01-09 | 1985-11-19 | New York Blood Center, Inc. | Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity |
| US4522811A (en) | 1982-07-08 | 1985-06-11 | Syntex (U.S.A.) Inc. | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides |
| US5168062A (en) | 1985-01-30 | 1992-12-01 | University Of Iowa Research Foundation | Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US5078996A (en) | 1985-08-16 | 1992-01-07 | Immunex Corporation | Activation of macrophage tumoricidal activity by granulocyte-macrophage colony stimulating factor |
| ATE141646T1 (de) | 1986-04-09 | 1996-09-15 | Genzyme Corp | Genetisch transformierte tiere, die ein gewünschtes protein in milch absondern |
| US5057540A (en) | 1987-05-29 | 1991-10-15 | Cambridge Biotech Corporation | Saponin adjuvant |
| US4873316A (en) | 1987-06-23 | 1989-10-10 | Biogen, Inc. | Isolation of exogenous recombinant proteins from the milk of transgenic mammals |
| US4912094B1 (en) | 1988-06-29 | 1994-02-15 | Ribi Immunochem Research Inc. | Modified lipopolysaccharides and process of preparation |
| US5703055A (en) | 1989-03-21 | 1997-12-30 | Wisconsin Alumni Research Foundation | Generation of antibodies through lipid mediated DNA delivery |
| IL101715A (en) | 1991-05-02 | 2005-06-19 | Amgen Inc | Recombinant dna-derived cholera toxin subunit analogs |
| CA2123811C (en) * | 1991-11-22 | 2005-07-05 | Ali Ibrahim Fattom | Type i and type ii surface antigens associated with staphylococcus epidermidis |
| US5769047A (en) | 1991-12-23 | 1998-06-23 | Zoche; Michael | Engine with oil separator |
| EP1033135A1 (en) | 1992-03-19 | 2000-09-06 | Henry M. Jackson Foundation For The Advancement Of Military Medicine | Broadly reactive opsonic antibodies that react with common staphyloccoccal antigens |
| US5593972A (en) | 1993-01-26 | 1997-01-14 | The Wistar Institute | Genetic immunization |
| DE69434469T2 (de) * | 1993-01-26 | 2006-06-14 | Univ Pennsylvania | Zusammensetzungen und verfahren zur verabreichung von genetischem material |
| US6995008B1 (en) * | 1994-03-07 | 2006-02-07 | Merck & Co., Inc. | Coordinate in vivo gene expression |
| IL112820A0 (en) * | 1994-03-07 | 1995-05-26 | Merck & Co Inc | Coordinate in vivo gene expression |
| US5571515A (en) | 1994-04-18 | 1996-11-05 | The Wistar Institute Of Anatomy & Biology | Compositions and methods for use of IL-12 as an adjuvant |
| US5505947A (en) | 1994-05-27 | 1996-04-09 | The University Of North Carolina At Chapel Hill | Attenuating mutations in Venezuelan Equine Encephalitis virus |
| US6207646B1 (en) | 1994-07-15 | 2001-03-27 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
| JP4160633B2 (ja) * | 1994-09-21 | 2008-10-01 | ヘンリー エム.ジャクソン ファウンデーション フォー ザ アドバンスメント オブ ミリタリー メディスン | 共通のブドウ球菌抗原と広範に反応するオプソニン作用性抗体 |
| US5837533A (en) | 1994-09-28 | 1998-11-17 | American Home Products Corporation | Complexes comprising a nucleic acid bound to a cationic polyamine having an endosome disruption agent |
| US7153510B1 (en) | 1995-05-04 | 2006-12-26 | Yale University | Recombinant vesiculoviruses and their uses |
| EP0857214A1 (en) * | 1995-10-16 | 1998-08-12 | Smithkline Beecham Plc | Novel saliva binding protein |
| US6168918B1 (en) | 1996-01-31 | 2001-01-02 | American Home Products Corp. | Method of detecting foreign DNA integrated in eukaryotic chromosomes |
| US6113918A (en) | 1997-05-08 | 2000-09-05 | Ribi Immunochem Research, Inc. | Aminoalkyl glucosamine phosphate compounds and their use as adjuvants and immunoeffectors |
| US7060458B1 (en) * | 1997-08-14 | 2006-06-13 | Wyeth | Nucleic acid and amino acid sequences relating to Staphylococcus epidermidis for diagnostics and therapeutics |
| US6380370B1 (en) * | 1997-08-14 | 2002-04-30 | Genome Therapeutics Corporation | Nucleic acid and amino acid sequences relating to Staphylococcus epidermidis for diagnostics and therapeutics |
| WO2000012689A1 (en) * | 1998-08-31 | 2000-03-09 | The Provost Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth Near Dublin | Polypeptides and polynucleotides from coagulase-negative staphylococci |
| PT1117435E (pt) | 1998-09-30 | 2008-02-21 | Us Gov Univ Health Sciences | Holotoxina da cólera mutante como adjuvante |
| US6703492B1 (en) * | 1999-11-09 | 2004-03-09 | Smithkline Beecham Corporation | Staphylococcus epidermidis nucleic acids and proteins |
| AU1478301A (en) | 1999-11-09 | 2001-06-06 | Glaxo Group Limited | Staphylococcus epidermidis nucleic acids and proteins |
| GB0014907D0 (en) | 2000-06-20 | 2000-08-09 | Univ Sheffield | Antigenic polypeptides |
| AT410798B (de) | 2001-01-26 | 2003-07-25 | Cistem Biotechnologies Gmbh | Verfahren zur identifizierung, isolierung und herstellung von antigenen gegen ein spezifisches pathogen |
| US20020169288A1 (en) * | 2001-03-15 | 2002-11-14 | Magnus Hook | Collagen-binding adhesin from staphylococcus epidermidis and method of use |
| BR0210216A (pt) | 2001-06-07 | 2004-06-08 | Wyeth Corp | Holotoxina do cólera imunogênica, mutante (ct-crm), composição imunogênica, métodos para aumentar a resposta imune de um hospedeiro vertebrado a um antìgeno, e para produzir uma holotoxina do cólera imunogênica, mutante, sequência ou molécula de ácido nucleico isolado e purificado, célula hospedeira, e, uso de uma holotoxina do cólera mutante |
| CN1977971A (zh) | 2001-06-07 | 2007-06-13 | 惠氏控股有限公司 | 作为佐剂的霍乱全毒素的突变体形式 |
| EP1412379B1 (en) | 2001-08-02 | 2012-01-25 | The University Of Sheffield | Vaccine |
| CN100351260C (zh) * | 2002-11-12 | 2007-11-28 | 布赖汉姆妇女医院 | 葡萄球菌感染的多糖疫苗 |
| CA2519511A1 (en) | 2003-03-17 | 2004-09-30 | Wyeth Holdings Corporation | Mutant cholera holotoxin as an adjuvant and an antigen carrier protein |
| US7628994B2 (en) | 2003-03-31 | 2009-12-08 | Intercell Ag | S. epidermidis antigens |
| JP2008513406A (ja) | 2004-09-22 | 2008-05-01 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | 免疫原性組成物 |
| CA2868867A1 (en) | 2005-03-25 | 2006-09-28 | National Research Council Of Canada | Method of isolation of soluble polypeptides |
-
2005
- 2005-10-19 EP EP10182802A patent/EP2340848A3/en not_active Withdrawn
- 2005-10-19 KR KR1020077011032A patent/KR20070068455A/ko not_active Withdrawn
- 2005-10-19 AU AU2005333603A patent/AU2005333603A1/en not_active Abandoned
- 2005-10-19 EP EP09008910A patent/EP2213298A3/en not_active Withdrawn
- 2005-10-19 US US11/665,940 patent/US8445000B2/en not_active Expired - Fee Related
- 2005-10-19 EP EP10182797A patent/EP2298341A3/en not_active Withdrawn
- 2005-10-19 EP EP05858253A patent/EP1802335A2/en not_active Withdrawn
- 2005-10-19 BR BRPI0516974-7A patent/BRPI0516974A/pt not_active IP Right Cessation
- 2005-10-19 CN CNA2005800360186A patent/CN101175508A/zh active Pending
- 2005-10-19 JP JP2007538033A patent/JP2008517918A/ja active Pending
- 2005-10-19 TW TW094136450A patent/TW200619228A/zh unknown
- 2005-10-19 CA CA002583121A patent/CA2583121A1/en not_active Abandoned
- 2005-10-19 WO PCT/US2005/037746 patent/WO2007001423A2/en not_active Ceased
- 2005-10-20 AR ARP050104384A patent/AR051826A1/es unknown
-
2007
- 2007-04-12 IL IL182546A patent/IL182546A0/en unknown
- 2007-04-20 ZA ZA200703274A patent/ZA200703274B/xx unknown
-
2013
- 2013-02-06 JP JP2013021337A patent/JP2013121981A/ja active Pending
- 2013-04-19 US US13/866,288 patent/US20130209501A1/en not_active Abandoned
-
2015
- 2015-03-31 US US14/674,512 patent/US20150196629A1/en not_active Abandoned
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