JP2019537424A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2019537424A5 JP2019537424A5 JP2019512267A JP2019512267A JP2019537424A5 JP 2019537424 A5 JP2019537424 A5 JP 2019537424A5 JP 2019512267 A JP2019512267 A JP 2019512267A JP 2019512267 A JP2019512267 A JP 2019512267A JP 2019537424 A5 JP2019537424 A5 JP 2019537424A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- protein
- recombinant protein
- acid sequence
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022186724A JP7500692B2 (ja) | 2016-09-02 | 2022-11-22 | 安定化されたグループ２インフルエンザヘマグルチニンステム領域三量体およびその使用 |
| JP2024091170A JP2024123036A (ja) | 2016-09-02 | 2024-06-05 | 安定化されたグループ２インフルエンザヘマグルチニンステム領域三量体およびその使用 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662383267P | 2016-09-02 | 2016-09-02 | |
| US62/383,267 | 2016-09-02 | ||
| PCT/US2017/049894 WO2018045308A1 (en) | 2016-09-02 | 2017-09-01 | Stabilized group 2 influenza hemagglutinin stem region trimers and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022186724A Division JP7500692B2 (ja) | 2016-09-02 | 2022-11-22 | 安定化されたグループ２インフルエンザヘマグルチニンステム領域三量体およびその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019537424A JP2019537424A (ja) | 2019-12-26 |
| JP2019537424A5 true JP2019537424A5 (enExample) | 2020-09-17 |
| JP7183149B2 JP7183149B2 (ja) | 2022-12-05 |
Family
ID=59887401
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019512267A Active JP7183149B2 (ja) | 2016-09-02 | 2017-09-01 | 安定化されたグループ２インフルエンザヘマグルチニンステム領域三量体およびその使用 |
| JP2022186724A Active JP7500692B2 (ja) | 2016-09-02 | 2022-11-22 | 安定化されたグループ２インフルエンザヘマグルチニンステム領域三量体およびその使用 |
| JP2024091170A Pending JP2024123036A (ja) | 2016-09-02 | 2024-06-05 | 安定化されたグループ２インフルエンザヘマグルチニンステム領域三量体およびその使用 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022186724A Active JP7500692B2 (ja) | 2016-09-02 | 2022-11-22 | 安定化されたグループ２インフルエンザヘマグルチニンステム領域三量体およびその使用 |
| JP2024091170A Pending JP2024123036A (ja) | 2016-09-02 | 2024-06-05 | 安定化されたグループ２インフルエンザヘマグルチニンステム領域三量体およびその使用 |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US11338033B2 (enExample) |
| EP (1) | EP3506938A1 (enExample) |
| JP (3) | JP7183149B2 (enExample) |
| KR (2) | KR20190056382A (enExample) |
| CN (2) | CN110167585B (enExample) |
| AU (2) | AU2017321883B2 (enExample) |
| BR (1) | BR112019004189A2 (enExample) |
| CA (1) | CA3035443A1 (enExample) |
| IL (3) | IL265121B2 (enExample) |
| SG (2) | SG10201912944QA (enExample) |
| WO (1) | WO2018045308A1 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3054971B1 (en) | 2013-10-11 | 2021-03-10 | The United States of America, represented by the Secretary, Department of Health and Human Services | Epstein-barr virus vaccines |
| CN110167585B (zh) * | 2016-09-02 | 2024-03-08 | 美国卫生与公众服务部 | 稳定化的第2组流感血凝素茎区三聚体及其用途 |
| GB2578163A (en) * | 2018-10-19 | 2020-04-22 | Univ Pretoria | Plant produced avian influenza antigens and their uses in diagnostic assays and devices |
| CN113423718A (zh) | 2019-02-08 | 2021-09-21 | 美国政府(由卫生和人类服务部的部长所代表) | 基于纳米颗粒的流感病毒疫苗及其用途 |
| EP4110384A4 (en) * | 2020-02-26 | 2024-07-31 | The Wistar Institute of Anatomy and Biology | COMPOSITIONS CONTAINING SELF-ASSEMBLING VACCINES AND METHODS OF USE THEREOF |
| CN111560074B (zh) * | 2020-03-20 | 2021-07-09 | 中山大学 | 一种基于幽门螺旋杆菌铁蛋白的新型冠状病毒s蛋白单区域亚单位纳米疫苗 |
| WO2021231729A1 (en) | 2020-05-13 | 2021-11-18 | Sanofi | Adjuvanted stabilized stem hemagglutinin nanoparticles and methods of using the same to induce broadly neutralizing antibodies against influenza |
| US20240165224A1 (en) | 2021-03-26 | 2024-05-23 | Glaxosmithkline Biologicals Sa | Immunogenic compositions |
| EP4313152A1 (en) | 2021-03-26 | 2024-02-07 | GlaxoSmithKline Biologicals S.A. | Immunogenic compositions |
| US20250281595A1 (en) | 2021-06-28 | 2025-09-11 | Glaxosmithkline Biologicals Sa | Novel influenza antigens |
| AU2022345984A1 (en) * | 2021-09-16 | 2024-04-04 | Emergent Product Development Gaithersburg Inc. | Vaccine compositions |
| WO2023061993A1 (en) | 2021-10-13 | 2023-04-20 | Glaxosmithkline Biologicals Sa | Polypeptides |
| GB202219228D0 (en) | 2022-12-20 | 2023-02-01 | Glaxosmithkline Biologicals Sa | Novel influenza antigens |
| WO2024131862A1 (zh) * | 2022-12-22 | 2024-06-27 | 北京吉诺卫生物科技有限公司 | 一种rsv疫苗及其制备方法与应用 |
| CN115850396B (zh) * | 2022-12-22 | 2024-02-06 | 北京吉诺卫生物科技有限公司 | 一种rsv纳米颗粒疫苗及其制备方法与应用 |
| WO2024163912A2 (en) * | 2023-02-03 | 2024-08-08 | The Children's Medical Center Corporation | Vaccine and therapeutic protein delivery compositions comprising fusion proteins |
| WO2024167855A1 (en) | 2023-02-06 | 2024-08-15 | Emergent Product Development Gaithersburg Inc. | Influenza hemagglutinin constructs and compositions |
| WO2024197134A1 (en) * | 2023-03-21 | 2024-09-26 | President And Fellows Of Harvard College | Coronavirus spike protein-based vaccines |
Family Cites Families (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6337070B1 (en) | 1993-04-29 | 2002-01-08 | Takara Shuzo Co., Ltd. | Polypeptides for use in generating anti-human influenza virus antibodies |
| AUPQ912000A0 (en) | 2000-07-31 | 2000-08-24 | Crown In The Right Of The Queensland Department Of Health, The | Improved virus like particles |
| CA2462455C (en) | 2001-10-01 | 2012-07-17 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Development of a preventive vaccine for filovirus infection in primates |
| US20050108791A1 (en) | 2001-12-04 | 2005-05-19 | Edgerton Michael D. | Transgenic plants with improved phenotypes |
| US7097841B2 (en) | 2002-05-10 | 2006-08-29 | New Century Pharmaceuticals, Inc. | Ferritin fusion proteins for use in vaccines and other applications |
| AU2003246690B2 (en) * | 2002-07-17 | 2010-03-11 | Cytos Biotechnology Ag | Molecular antigen arrays using a virus like particle derived from the AP205 coat protein |
| CN102268094A (zh) * | 2002-08-30 | 2011-12-07 | 比奥雷克西斯药物公司 | 被修饰的转铁蛋白抗体的融合蛋白 |
| EP1633312A4 (en) | 2003-06-16 | 2012-09-26 | Medimmune Llc | INFLUENZA HEMAGGLUTININE AND NEURAMINIDASE VARIANTS |
| GB0319797D0 (en) | 2003-08-26 | 2003-09-24 | Leuven K U Res & Dev | Particle size reduction of poorly soluble drugs |
| US7897408B2 (en) | 2005-09-12 | 2011-03-01 | Japan Science And Technology Agency | Method for producing CdS-apoferritin and ZnS-apoferritin complexes |
| ES2555544T3 (es) | 2006-03-07 | 2016-01-04 | Vaxinnate Corporation | Composiciones que incluyen hemaglutinina, métodos de preparación y métodos de uso de las mismas |
| MX2009007106A (es) | 2006-12-29 | 2010-04-30 | Inst Pasteur Of Shanghai | Lentivirus pseudotipificado con hemaglutinina de influenza y metodos de uso. |
| US20080299151A1 (en) | 2007-05-31 | 2008-12-04 | Statens Serum Institut | Influenza vaccines |
| WO2008157419A2 (en) | 2007-06-13 | 2008-12-24 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Immunogenic peptides of influenza virus |
| CA2696764A1 (en) | 2007-08-20 | 2009-02-26 | Fraunhofer Usa, Inc. | Prophylactic and therapeutic influenza vaccines, antigens, compositions, and methods |
| WO2009109428A2 (en) | 2008-02-01 | 2009-09-11 | Alpha-O Peptides Ag | Self-assembling peptide nanoparticles useful as vaccines |
| JP5382489B2 (ja) | 2008-03-29 | 2014-01-08 | 国立大学法人 奈良先端科学技術大学院大学 | 円偏光発光性ナノ微粒子 |
| US20110177122A1 (en) | 2008-09-26 | 2011-07-21 | The United States Of America, As Represented By The Secretary, Dept. Of Health & Human Services | Dna prime/activated vaccine boost immunization to influenza virus |
| CA2787099A1 (en) | 2009-03-30 | 2010-10-14 | Anice C. Lowen | Influenza virus hemagglutinin polypeptides containing stem domains, vaccines and uses thereof |
| SI3354657T1 (sl) | 2009-09-22 | 2022-05-31 | Medicago Inc. | Postopek za pripravo iz rastlin izpeljanih beljakovin |
| US20120219584A1 (en) | 2009-10-05 | 2012-08-30 | The United States Of America As Represented By The Secretary, Department Of Health | Protection against pandemic and seasonal strains of influenza |
| WO2011102900A1 (en) | 2010-02-18 | 2011-08-25 | Technovax, Inc. | Universal virus-like particle (vlp) influenza vaccines |
| AU2011344126B2 (en) * | 2010-12-13 | 2016-11-10 | The University Of Utah Research Foundation | Vaccine antigens that direct immunity to conserved epitopes |
| WO2012162428A1 (en) | 2011-05-23 | 2012-11-29 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Prime-boost vaccination for viral infection |
| EP2758075B1 (en) | 2011-09-20 | 2023-05-03 | Icahn School of Medicine at Mount Sinai | Influenza virus vaccines and uses thereof |
| WO2013044203A2 (en) | 2011-09-23 | 2013-03-28 | THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPTARTMENT OF HEALTH & HUMAN SERVICES | Novel influenza hemagglutinin protein-based vaccines |
| IN2014CN04742A (enExample) | 2011-11-28 | 2015-09-18 | Crucell Holland Bv | |
| JP2015519348A (ja) | 2012-05-23 | 2015-07-09 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティ | インフルエンザワクチン構築物 |
| EP2934581B1 (en) | 2012-12-18 | 2022-09-14 | Icahn School of Medicine at Mount Sinai | Influenza virus vaccines and uses thereof |
| CN105452270B (zh) | 2013-05-30 | 2020-12-01 | 扬森疫苗与预防公司 | 流行性感冒病毒疫苗及其用途 |
| EP3054971B1 (en) | 2013-10-11 | 2021-03-10 | The United States of America, represented by the Secretary, Department of Health and Human Services | Epstein-barr virus vaccines |
| SI3063273T1 (sl) | 2013-10-28 | 2020-03-31 | Blue Sky Vaccines Gmbh | Vektor virusa gripe za viroterapijo |
| US10363301B2 (en) | 2014-05-27 | 2019-07-30 | The United States Of America As Represented By The Secretary, Department Of Health And Human Services | Stabilized influenza hemagglutinin stem region trimers and uses thereof |
| KR102463632B1 (ko) * | 2014-07-10 | 2022-11-03 | 얀센 백신스 앤드 프리벤션 비.브이. | 인플루엔자 바이러스 백신 및 이의 용도 |
| TWI720946B (zh) | 2014-08-08 | 2021-03-11 | 美商Ｖｌｐ醫療股份有限公司 | 包含改質套膜蛋白質ｅ３之類病毒粒子 |
| BR112017014219A2 (en) | 2014-12-31 | 2018-03-06 | The Usa, As Represented By The Secretary, Dept. Of Health And Human Services | multivalent nanoparticle-based vaccines |
| EP3474893A1 (en) | 2016-06-27 | 2019-05-01 | The U.S.A. as represented by the Secretary, Department of Health and Human Services | Self-assembling insect ferritin nanoparticles for display of co-assembled trimeric antigens |
| CN110167585B (zh) * | 2016-09-02 | 2024-03-08 | 美国卫生与公众服务部 | 稳定化的第2组流感血凝素茎区三聚体及其用途 |
| WO2021231729A1 (en) * | 2020-05-13 | 2021-11-18 | Sanofi | Adjuvanted stabilized stem hemagglutinin nanoparticles and methods of using the same to induce broadly neutralizing antibodies against influenza |
-
2017
- 2017-09-01 CN CN201780066267.2A patent/CN110167585B/zh active Active
- 2017-09-01 AU AU2017321883A patent/AU2017321883B2/en active Active
- 2017-09-01 JP JP2019512267A patent/JP7183149B2/ja active Active
- 2017-09-01 KR KR1020197009334A patent/KR20190056382A/ko not_active Ceased
- 2017-09-01 SG SG10201912944QA patent/SG10201912944QA/en unknown
- 2017-09-01 BR BR112019004189-3A patent/BR112019004189A2/pt unknown
- 2017-09-01 SG SG11201901790YA patent/SG11201901790YA/en unknown
- 2017-09-01 US US16/329,592 patent/US11338033B2/en active Active
- 2017-09-01 KR KR1020247010062A patent/KR20240042570A/ko active Pending
- 2017-09-01 WO PCT/US2017/049894 patent/WO2018045308A1/en not_active Ceased
- 2017-09-01 IL IL265121A patent/IL265121B2/en unknown
- 2017-09-01 CA CA3035443A patent/CA3035443A1/en active Pending
- 2017-09-01 EP EP17768316.6A patent/EP3506938A1/en active Pending
- 2017-09-01 IL IL303650A patent/IL303650B2/en unknown
- 2017-09-01 IL IL315821A patent/IL315821A/en unknown
- 2017-09-01 CN CN202410185751.9A patent/CN118146389A/zh active Pending
-
2022
- 2022-05-11 US US17/742,201 patent/US11793871B2/en active Active
- 2022-10-07 AU AU2022246465A patent/AU2022246465B2/en active Active
- 2022-11-22 JP JP2022186724A patent/JP7500692B2/ja active Active
-
2023
- 2023-10-20 US US18/491,193 patent/US12527857B2/en active Active
-
2024
- 2024-06-05 JP JP2024091170A patent/JP2024123036A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2023018073A5 (enExample) | ||
| US12527857B2 (en) | Stabilized group 2 influenza hemagglutinin stem region trimers and uses thereof | |
| US12433943B2 (en) | Nanoparticle-based influenza virus vaccines and uses thereof | |
| TWI874544B (zh) | 變異型rsv f蛋白質及其利用 | |
| CN107488218B (zh) | 一种多肽、免疫原性偶联物和流感疫苗 | |
| KR102777000B1 (ko) | 인플루엔자 바이러스 백신 및 이의 용도 | |
| WO2012163289A1 (zh) | 包含白喉毒素无毒突变体crm197或其片段的融合蛋白 | |
| CN105452270A (zh) | 流行性感冒病毒疫苗及其用途 | |
| JP2015509707A5 (enExample) | ||
| JP2018531578A5 (enExample) | ||
| US20160000901A1 (en) | Compositions and Methods for the Production of Virus-Like Particles | |
| CN107344969A (zh) | 一种纳米流感疫苗及构建方法和应用 | |
| WO2024199469A1 (zh) | 具有稳定融合前构象的呼吸道合胞病毒f蛋白 | |
| JP7545955B2 (ja) | インフルエンザｈａスプリットワクチンの製造方法 | |
| Lim et al. | RNA-dependent assembly of chimeric antigen nanoparticles as an efficient H5N1 pre-pandemic vaccine platform | |
| Zhu et al. | Protection against the H1N1 influenza virus using self-assembled nanoparticles formed by lumazine synthase and bearing the M2e peptide | |
| Sheng et al. | Apoferritin nanoparticle based dual-antigen influenza conjugate vaccine with potential cross-protective efficacy against heterosubtypic influenza virus | |
| WO2018175560A1 (en) | Nanoparticle immunogens to elicit responses against the influenza receptor binding site on the hemagglutinin head domain | |
| WO2020246584A1 (ja) | ペプチド核酸を基盤としたアジュバント | |
| CN110201183A (zh) | 一种可同时递送抗原和免疫增强剂的纳米制剂 | |
| Kotlyarov et al. | Development of recombinant vaccine against A (H1N1) 2009 influenza based on virus-like nanoparticles carrying the extracellular domain of M2 protein | |
| CN106337038B (zh) | 一种通过转肽酶剪切制备疫苗的方法及其应用 | |
| CN103242426B (zh) | 禽流感病毒h5n1亚型限制性ctl表位多肽及其应用 |