SG10201912944QA - Stabilized group 2 influenza hemagglutinin stem region trimers and uses thereof - Google Patents
Stabilized group 2 influenza hemagglutinin stem region trimers and uses thereofInfo
- Publication number
- SG10201912944QA SG10201912944QA SG10201912944QA SG10201912944QA SG10201912944QA SG 10201912944Q A SG10201912944Q A SG 10201912944QA SG 10201912944Q A SG10201912944Q A SG 10201912944QA SG 10201912944Q A SG10201912944Q A SG 10201912944QA SG 10201912944Q A SG10201912944Q A SG 10201912944QA
- Authority
- SG
- Singapore
- Prior art keywords
- trimers
- influenza hemagglutinin
- stem region
- hemagglutinin stem
- stabilized group
- Prior art date
Links
- 101710154606 Hemagglutinin Proteins 0.000 title 1
- 101710093908 Outer capsid protein VP4 Proteins 0.000 title 1
- 101710135467 Outer capsid protein sigma-1 Proteins 0.000 title 1
- 101710176177 Protein A56 Proteins 0.000 title 1
- 239000000185 hemagglutinin Substances 0.000 title 1
- 206010022000 influenza Diseases 0.000 title 1
- 239000013638 trimer Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/145—Orthomyxoviridae, e.g. influenza virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56983—Viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
- G01N2333/08—RNA viruses
- G01N2333/11—Orthomyxoviridae, e.g. influenza virus
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662383267P | 2016-09-02 | 2016-09-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG10201912944QA true SG10201912944QA (en) | 2020-02-27 |
Family
ID=59887401
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10201912944QA SG10201912944QA (en) | 2016-09-02 | 2017-09-01 | Stabilized group 2 influenza hemagglutinin stem region trimers and uses thereof |
| SG11201901790YA SG11201901790YA (en) | 2016-09-02 | 2017-09-01 | Stabilized group 2 influenza hemagglutinin stem region trimers and uses thereof |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201901790YA SG11201901790YA (en) | 2016-09-02 | 2017-09-01 | Stabilized group 2 influenza hemagglutinin stem region trimers and uses thereof |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US11338033B2 (en) |
| EP (1) | EP3506938A1 (en) |
| JP (2) | JP7183149B2 (en) |
| KR (2) | KR20190056382A (en) |
| CN (1) | CN110167585B (en) |
| AU (2) | AU2017321883B2 (en) |
| BR (1) | BR112019004189A2 (en) |
| CA (1) | CA3035443A1 (en) |
| IL (2) | IL265121B2 (en) |
| SG (2) | SG10201912944QA (en) |
| WO (1) | WO2018045308A1 (en) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3506938A1 (en) * | 2016-09-02 | 2019-07-10 | The U.S.A. as represented by the Secretary, Department of Health and Human Services | Stabilized group 2 influenza hemagglutinin stem region trimers and uses thereof |
| GB2578163A (en) * | 2018-10-19 | 2020-04-22 | Univ Pretoria | Plant produced avian influenza antigens and their uses in diagnostic assays and devices |
| AU2020219803A1 (en) | 2019-02-08 | 2021-08-05 | The Usa, As Represented By The Secretary, Department Of Health And Human Services | Nanoparticle-based influenza virus vaccines and uses thereof |
| CN111560074B (en) * | 2020-03-20 | 2021-07-09 | 中山大学 | Novel coronavirus S protein single-region subunit nano vaccine based on helicobacter pylori ferritin |
| WO2021231729A1 (en) | 2020-05-13 | 2021-11-18 | Sanofi | Adjuvanted stabilized stem hemagglutinin nanoparticles and methods of using the same to induce broadly neutralizing antibodies against influenza |
| WO2022200582A1 (en) | 2021-03-26 | 2022-09-29 | Glaxosmithkline Biologicals Sa | Immunogenic compositions |
| CA3212653A1 (en) | 2021-03-26 | 2022-09-29 | Glaxosmithkline Biologicals Sa | Immunogenic compositions |
| WO2023274860A1 (en) | 2021-06-28 | 2023-01-05 | Glaxosmithkline Biologicals Sa | Novel influenza antigens |
| WO2023044388A1 (en) | 2021-09-16 | 2023-03-23 | Emergent Product Development Gaithersburg Inc. | Vaccine compositions |
| WO2023061993A1 (en) | 2021-10-13 | 2023-04-20 | Glaxosmithkline Biologicals Sa | Polypeptides |
| CN115850396B (en) * | 2022-12-22 | 2024-02-06 | 北京吉诺卫生物科技有限公司 | RSV nanoparticle vaccine and preparation method and application thereof |
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| US6337070B1 (en) | 1993-04-29 | 2002-01-08 | Takara Shuzo Co., Ltd. | Polypeptides for use in generating anti-human influenza virus antibodies |
| AUPQ912000A0 (en) | 2000-07-31 | 2000-08-24 | Crown In The Right Of The Queensland Department Of Health, The | Improved virus like particles |
| AU2002327049B2 (en) | 2001-10-01 | 2008-04-03 | Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Development of a preventive vaccine for filovirus infection in primates |
| US20050108791A1 (en) | 2001-12-04 | 2005-05-19 | Edgerton Michael D. | Transgenic plants with improved phenotypes |
| US7097841B2 (en) | 2002-05-10 | 2006-08-29 | New Century Pharmaceuticals, Inc. | Ferritin fusion proteins for use in vaccines and other applications |
| EP2351770A1 (en) | 2002-07-17 | 2011-08-03 | Cytos Biotechnology AG | Molecular antigen arrays using a virus like particle derived from the ap205 coat protein |
| ES2347144T3 (en) * | 2002-08-30 | 2010-10-26 | Biorexis Pharmaceutical Corporation | FUSION PROTEINS OF THE MODIFIED TRANSFERRINE THAT INCLUDE DOMINOS AINO OR CARBOXILO OF TRANSFERRINA DUPLICATED. |
| EP2581093B1 (en) | 2003-06-16 | 2015-03-18 | MedImmune, LLC | Influenza hemagglutinin and neuraminidase variants |
| GB0319797D0 (en) | 2003-08-26 | 2003-09-24 | Leuven K U Res & Dev | Particle size reduction of poorly soluble drugs |
| US7897408B2 (en) | 2005-09-12 | 2011-03-01 | Japan Science And Technology Agency | Method for producing CdS-apoferritin and ZnS-apoferritin complexes |
| TW200745158A (en) | 2006-03-07 | 2007-12-16 | Vaxinnate Corp | Compositions that include hemagglutinin, methods of making and methods of use thereof |
| WO2008087563A2 (en) | 2006-12-29 | 2008-07-24 | Institut Pasteur Of Shanghai | Lentivirus pseudotyped with influenza hemagglutinin and methods of use |
| US20080299151A1 (en) | 2007-05-31 | 2008-12-04 | Statens Serum Institut | Influenza vaccines |
| US8778847B2 (en) | 2007-06-13 | 2014-07-15 | The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services | Immunogenic peptides of influenza virus |
| US20110059130A1 (en) | 2007-08-20 | 2011-03-10 | Fraunhofer Usa, Inc. | Prophylactic and therapeutic influenza vaccines, antigens, compositions and methods |
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| PL3148578T3 (en) * | 2014-05-27 | 2022-10-17 | The U.S.A. As Represented By The Secretary, Department Of Health And Human Services | Stabilized influenza hemagglutinin stem region trimers and uses thereof |
| CN107074912B (en) | 2014-07-10 | 2021-10-29 | 扬森疫苗与预防公司 | Influenza virus vaccine and uses thereof |
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| EP3506938A1 (en) * | 2016-09-02 | 2019-07-10 | The U.S.A. as represented by the Secretary, Department of Health and Human Services | Stabilized group 2 influenza hemagglutinin stem region trimers and uses thereof |
| WO2021231729A1 (en) * | 2020-05-13 | 2021-11-18 | Sanofi | Adjuvanted stabilized stem hemagglutinin nanoparticles and methods of using the same to induce broadly neutralizing antibodies against influenza |
-
2017
- 2017-09-01 EP EP17768316.6A patent/EP3506938A1/en active Pending
- 2017-09-01 KR KR1020197009334A patent/KR20190056382A/en active Application Filing
- 2017-09-01 SG SG10201912944QA patent/SG10201912944QA/en unknown
- 2017-09-01 WO PCT/US2017/049894 patent/WO2018045308A1/en unknown
- 2017-09-01 US US16/329,592 patent/US11338033B2/en active Active
- 2017-09-01 JP JP2019512267A patent/JP7183149B2/en active Active
- 2017-09-01 CN CN201780066267.2A patent/CN110167585B/en active Active
- 2017-09-01 BR BR112019004189A patent/BR112019004189A2/en unknown
- 2017-09-01 KR KR1020247010062A patent/KR20240042570A/en active Search and Examination
- 2017-09-01 CA CA3035443A patent/CA3035443A1/en active Pending
- 2017-09-01 IL IL265121A patent/IL265121B2/en unknown
- 2017-09-01 AU AU2017321883A patent/AU2017321883B2/en active Active
- 2017-09-01 SG SG11201901790YA patent/SG11201901790YA/en unknown
- 2017-09-01 IL IL303650A patent/IL303650A/en unknown
-
2022
- 2022-05-11 US US17/742,201 patent/US11793871B2/en active Active
- 2022-10-07 AU AU2022246465A patent/AU2022246465A1/en active Pending
- 2022-11-22 JP JP2022186724A patent/JP2023018073A/en active Pending
-
2023
- 2023-10-20 US US18/491,193 patent/US20240050554A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP7183149B2 (en) | 2022-12-05 |
| CN110167585A (en) | 2019-08-23 |
| EP3506938A1 (en) | 2019-07-10 |
| JP2019537424A (en) | 2019-12-26 |
| KR20190056382A (en) | 2019-05-24 |
| IL265121B2 (en) | 2023-11-01 |
| KR20240042570A (en) | 2024-04-02 |
| BR112019004189A2 (en) | 2019-06-25 |
| US20190192651A1 (en) | 2019-06-27 |
| IL265121B1 (en) | 2023-07-01 |
| IL303650A (en) | 2023-08-01 |
| US20220339278A1 (en) | 2022-10-27 |
| CN110167585B (en) | 2024-03-08 |
| US11793871B2 (en) | 2023-10-24 |
| AU2017321883B2 (en) | 2022-07-07 |
| JP2023018073A (en) | 2023-02-07 |
| AU2022246465A1 (en) | 2022-11-17 |
| WO2018045308A1 (en) | 2018-03-08 |
| CA3035443A1 (en) | 2018-03-08 |
| US11338033B2 (en) | 2022-05-24 |
| AU2017321883A1 (en) | 2019-04-18 |
| SG11201901790YA (en) | 2019-03-28 |
| US20240050554A1 (en) | 2024-02-15 |
| IL265121A (en) | 2019-04-30 |
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