SG10201912944QA - Stabilized group 2 influenza hemagglutinin stem region trimers and uses thereof - Google Patents
Stabilized group 2 influenza hemagglutinin stem region trimers and uses thereofInfo
- Publication number
- SG10201912944QA SG10201912944QA SG10201912944QA SG10201912944QA SG10201912944QA SG 10201912944Q A SG10201912944Q A SG 10201912944QA SG 10201912944Q A SG10201912944Q A SG 10201912944QA SG 10201912944Q A SG10201912944Q A SG 10201912944QA SG 10201912944Q A SG10201912944Q A SG 10201912944QA
- Authority
- SG
- Singapore
- Prior art keywords
- trimers
- influenza hemagglutinin
- stem region
- hemagglutinin stem
- stabilized group
- Prior art date
Links
- 101710154606 Hemagglutinin Proteins 0.000 title 1
- 101710093908 Outer capsid protein VP4 Proteins 0.000 title 1
- 101710135467 Outer capsid protein sigma-1 Proteins 0.000 title 1
- 101710176177 Protein A56 Proteins 0.000 title 1
- 239000000185 hemagglutinin Substances 0.000 title 1
- 206010022000 influenza Diseases 0.000 title 1
- 239000013638 trimer Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/145—Orthomyxoviridae, e.g. influenza virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56983—Viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/735—Fusion polypeptide containing domain for protein-protein interaction containing a domain for self-assembly, e.g. a viral coat protein (includes phage display)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
- G01N2333/08—RNA viruses
- G01N2333/11—Orthomyxoviridae, e.g. influenza virus
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pulmonology (AREA)
- Biophysics (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- General Physics & Mathematics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Pathology (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201662383267P | 2016-09-02 | 2016-09-02 |
Publications (1)
Publication Number | Publication Date |
---|---|
SG10201912944QA true SG10201912944QA (en) | 2020-02-27 |
Family
ID=59887401
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201901790YA SG11201901790YA (en) | 2016-09-02 | 2017-09-01 | Stabilized group 2 influenza hemagglutinin stem region trimers and uses thereof |
SG10201912944QA SG10201912944QA (en) | 2016-09-02 | 2017-09-01 | Stabilized group 2 influenza hemagglutinin stem region trimers and uses thereof |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201901790YA SG11201901790YA (en) | 2016-09-02 | 2017-09-01 | Stabilized group 2 influenza hemagglutinin stem region trimers and uses thereof |
Country Status (11)
Country | Link |
---|---|
US (3) | US11338033B2 (en) |
EP (1) | EP3506938A1 (en) |
JP (2) | JP7183149B2 (en) |
KR (2) | KR20240042570A (en) |
CN (2) | CN110167585B (en) |
AU (2) | AU2017321883B2 (en) |
BR (1) | BR112019004189A2 (en) |
CA (1) | CA3035443A1 (en) |
IL (2) | IL303650A (en) |
SG (2) | SG11201901790YA (en) |
WO (1) | WO2018045308A1 (en) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10744199B2 (en) | 2013-10-11 | 2020-08-18 | The Usa, As Represented By The Secretary, Dept. Of Health And Human Services | Epstein-Barr virus vaccines |
CN110167585B (en) * | 2016-09-02 | 2024-03-08 | 美国卫生与公众服务部 | Stabilized group 2 influenza hemagglutinin stem trimer and uses thereof |
GB2578163A (en) * | 2018-10-19 | 2020-04-22 | Univ Pretoria | Plant produced avian influenza antigens and their uses in diagnostic assays and devices |
US20220072120A1 (en) | 2019-02-08 | 2022-03-10 | The Usa, As Represented By The Secretary, Department Of Health And Human Services | Nanoparticle-based influenza virus vaccines and uses thereof |
CN111560074B (en) * | 2020-03-20 | 2021-07-09 | 中山大学 | Novel coronavirus S protein single-region subunit nano vaccine based on helicobacter pylori ferritin |
WO2021231729A1 (en) | 2020-05-13 | 2021-11-18 | Sanofi | Adjuvanted stabilized stem hemagglutinin nanoparticles and methods of using the same to induce broadly neutralizing antibodies against influenza |
WO2022200582A1 (en) | 2021-03-26 | 2022-09-29 | Glaxosmithkline Biologicals Sa | Immunogenic compositions |
US20240181037A1 (en) | 2021-03-26 | 2024-06-06 | Glaxosmithkline Biologicals Sa | Immunogenic compositions |
BR112023027401A2 (en) | 2021-06-28 | 2024-03-12 | Glaxosmithkline Biologicals Sa | INFLUENZA VIRUS ANTIGENS |
WO2023044388A1 (en) * | 2021-09-16 | 2023-03-23 | Emergent Product Development Gaithersburg Inc. | Vaccine compositions |
WO2023061993A1 (en) | 2021-10-13 | 2023-04-20 | Glaxosmithkline Biologicals Sa | Polypeptides |
GB202219228D0 (en) | 2022-12-20 | 2023-02-01 | Glaxosmithkline Biologicals Sa | Novel influenza antigens |
CN115850396B (en) * | 2022-12-22 | 2024-02-06 | 北京吉诺卫生物科技有限公司 | RSV nanoparticle vaccine and preparation method and application thereof |
WO2024131862A1 (en) * | 2022-12-22 | 2024-06-27 | 北京吉诺卫生物科技有限公司 | Rsv vaccine as well as preparation method therefor and use thereof |
Family Cites Families (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6337070B1 (en) | 1993-04-29 | 2002-01-08 | Takara Shuzo Co., Ltd. | Polypeptides for use in generating anti-human influenza virus antibodies |
AUPQ912000A0 (en) | 2000-07-31 | 2000-08-24 | Crown In The Right Of The Queensland Department Of Health, The | Improved virus like particles |
EP1504112A4 (en) | 2001-10-01 | 2006-02-08 | Us Health | Development of a preventive vaccine for filovirus infection in primates |
US20050108791A1 (en) | 2001-12-04 | 2005-05-19 | Edgerton Michael D. | Transgenic plants with improved phenotypes |
US7097841B2 (en) | 2002-05-10 | 2006-08-29 | New Century Pharmaceuticals, Inc. | Ferritin fusion proteins for use in vaccines and other applications |
CA2489410C (en) | 2002-07-17 | 2015-01-13 | Cytos Biotechnology Ag | Molecular antigen arrays |
AU2003262886A1 (en) * | 2002-08-30 | 2004-03-19 | Biorexis Pharmaceutical Corporation | Modified transferrin fusion proteins comprising duplicate transferrin amino or carboxy terminal domains |
WO2005018539A2 (en) | 2003-06-16 | 2005-03-03 | Medimmune Vaccines, Inc. | Influenza hemagglutinin and neuraminidase variants |
GB0319797D0 (en) | 2003-08-26 | 2003-09-24 | Leuven K U Res & Dev | Particle size reduction of poorly soluble drugs |
US7897408B2 (en) | 2005-09-12 | 2011-03-01 | Japan Science And Technology Agency | Method for producing CdS-apoferritin and ZnS-apoferritin complexes |
CA2638760A1 (en) | 2006-03-07 | 2007-09-13 | Vaxinnate Corporation | Compositions that include hemagglutinin, methods of making and methods of use thereof |
JP2010514439A (en) | 2006-12-29 | 2010-05-06 | インスティティ パスツール オブ シャンハイ | Lentivirus pseudotyped with influenza hemagglutinin and method of use thereof |
MX2009013008A (en) | 2007-05-31 | 2010-06-09 | Influenza vaccines. | |
US8778847B2 (en) | 2007-06-13 | 2014-07-15 | The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services | Immunogenic peptides of influenza virus |
EP2190472A2 (en) | 2007-08-20 | 2010-06-02 | Fraunhofer USA, Inc. | Prophylactic and therapeutic influenza vaccines, antigens, compositions, and methods |
EP2235043A2 (en) | 2008-02-01 | 2010-10-06 | Alpha-O Peptides AG | Self-assembling peptide nanoparticles useful as vaccines |
JP5382489B2 (en) | 2008-03-29 | 2014-01-08 | 国立大学法人 奈良先端科学技術大学院大学 | Circularly polarized light-emitting nanoparticles |
WO2010036948A2 (en) | 2008-09-26 | 2010-04-01 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Dna prime/inactivated vaccine boost immunization to influenza virus |
CA2787099A1 (en) * | 2009-03-30 | 2010-10-14 | Anice C. Lowen | Influenza virus hemagglutinin polypeptides containing stem domains, vaccines and uses thereof |
PT3354657T (en) | 2009-09-22 | 2022-05-06 | Medicago Inc | Method of preparing plant-derived proteins |
US20120219584A1 (en) | 2009-10-05 | 2012-08-30 | The United States Of America As Represented By The Secretary, Department Of Health | Protection against pandemic and seasonal strains of influenza |
EP2536428B1 (en) | 2010-02-18 | 2018-12-05 | Technovax, Inc. | Universal virus-like particle (vlp) influenza vaccines |
EP2652496B1 (en) * | 2010-12-13 | 2018-01-17 | The University of Utah Research Foundation | Vaccine antigens that direct immunity to conserved epitopes |
WO2012162428A1 (en) | 2011-05-23 | 2012-11-29 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Prime-boost vaccination for viral infection |
EP2758075B1 (en) | 2011-09-20 | 2023-05-03 | Icahn School of Medicine at Mount Sinai | Influenza virus vaccines and uses thereof |
US9441019B2 (en) * | 2011-09-23 | 2016-09-13 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Influenza hemagglutinin protein-based vaccines |
SG11201402633UA (en) * | 2011-11-28 | 2014-09-26 | Crucell Holland Bv | Influenza virus vaccines and uses thereof |
CN104582714A (en) | 2012-05-23 | 2015-04-29 | 斯坦福大学托管董事会 | Influenza vaccine constructs |
NZ627796A (en) * | 2012-12-18 | 2017-07-28 | Icahn School Med Mount Sinai | Influenza virus vaccines and uses thereof |
CA2913859C (en) * | 2013-05-30 | 2021-11-30 | Crucell Holland B.V. | Influenza virus vaccines and uses thereof |
US10744199B2 (en) | 2013-10-11 | 2020-08-18 | The Usa, As Represented By The Secretary, Dept. Of Health And Human Services | Epstein-Barr virus vaccines |
US10125374B2 (en) * | 2013-10-28 | 2018-11-13 | Blue Sky Vaccines Gmbh | Influenza virus vector for virotherapy |
US10363301B2 (en) | 2014-05-27 | 2019-07-30 | The United States Of America As Represented By The Secretary, Department Of Health And Human Services | Stabilized influenza hemagglutinin stem region trimers and uses thereof |
CN107074912B (en) | 2014-07-10 | 2021-10-29 | 扬森疫苗与预防公司 | Influenza virus vaccine and uses thereof |
WO2016021209A1 (en) | 2014-08-08 | 2016-02-11 | Vlp Therapeutics, Llc | Virus like particle comprising modified envelope protein e3 |
BR112017014219A2 (en) | 2014-12-31 | 2018-03-06 | The Usa As Represented By The Secretary Dept Of Health And Human Services | multivalent nanoparticle-based vaccines |
WO2018005558A1 (en) | 2016-06-27 | 2018-01-04 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Self-assembling insect ferritin nanoparticles for display of co-assembled trimeric antigens |
CN110167585B (en) * | 2016-09-02 | 2024-03-08 | 美国卫生与公众服务部 | Stabilized group 2 influenza hemagglutinin stem trimer and uses thereof |
WO2021231729A1 (en) * | 2020-05-13 | 2021-11-18 | Sanofi | Adjuvanted stabilized stem hemagglutinin nanoparticles and methods of using the same to induce broadly neutralizing antibodies against influenza |
-
2017
- 2017-09-01 CN CN201780066267.2A patent/CN110167585B/en active Active
- 2017-09-01 CN CN202410185751.9A patent/CN118146389A/en active Pending
- 2017-09-01 SG SG11201901790YA patent/SG11201901790YA/en unknown
- 2017-09-01 CA CA3035443A patent/CA3035443A1/en active Pending
- 2017-09-01 IL IL303650A patent/IL303650A/en unknown
- 2017-09-01 KR KR1020247010062A patent/KR20240042570A/en active Search and Examination
- 2017-09-01 WO PCT/US2017/049894 patent/WO2018045308A1/en unknown
- 2017-09-01 US US16/329,592 patent/US11338033B2/en active Active
- 2017-09-01 KR KR1020197009334A patent/KR20190056382A/en active Application Filing
- 2017-09-01 EP EP17768316.6A patent/EP3506938A1/en active Pending
- 2017-09-01 SG SG10201912944QA patent/SG10201912944QA/en unknown
- 2017-09-01 BR BR112019004189A patent/BR112019004189A2/en unknown
- 2017-09-01 AU AU2017321883A patent/AU2017321883B2/en active Active
- 2017-09-01 JP JP2019512267A patent/JP7183149B2/en active Active
- 2017-09-01 IL IL265121A patent/IL265121B2/en unknown
-
2022
- 2022-05-11 US US17/742,201 patent/US11793871B2/en active Active
- 2022-10-07 AU AU2022246465A patent/AU2022246465B2/en active Active
- 2022-11-22 JP JP2022186724A patent/JP7500692B2/en active Active
-
2023
- 2023-10-20 US US18/491,193 patent/US20240050554A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
CN110167585A (en) | 2019-08-23 |
EP3506938A1 (en) | 2019-07-10 |
JP2019537424A (en) | 2019-12-26 |
JP2023018073A (en) | 2023-02-07 |
IL265121B1 (en) | 2023-07-01 |
JP7183149B2 (en) | 2022-12-05 |
AU2017321883A1 (en) | 2019-04-18 |
JP7500692B2 (en) | 2024-06-17 |
KR20190056382A (en) | 2019-05-24 |
CN110167585B (en) | 2024-03-08 |
US11338033B2 (en) | 2022-05-24 |
SG11201901790YA (en) | 2019-03-28 |
US20240050554A1 (en) | 2024-02-15 |
US20220339278A1 (en) | 2022-10-27 |
IL303650A (en) | 2023-08-01 |
KR20240042570A (en) | 2024-04-02 |
CA3035443A1 (en) | 2018-03-08 |
IL265121B2 (en) | 2023-11-01 |
IL265121A (en) | 2019-04-30 |
US20190192651A1 (en) | 2019-06-27 |
AU2022246465A1 (en) | 2022-11-17 |
BR112019004189A2 (en) | 2019-06-25 |
US11793871B2 (en) | 2023-10-24 |
AU2022246465B2 (en) | 2024-05-30 |
WO2018045308A1 (en) | 2018-03-08 |
CN118146389A (en) | 2024-06-07 |
AU2017321883B2 (en) | 2022-07-07 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
SG10201912944QA (en) | Stabilized group 2 influenza hemagglutinin stem region trimers and uses thereof | |
PL3148578T3 (en) | Stabilized influenza hemagglutinin stem region trimers and uses thereof | |
ZA201901246B (en) | Distributed systems for the efficient production and use of microbe-based compositions | |
DK3889145T3 (en) | 8-cyano-5-piperidino-quinolines as TLR7/8 antagonists and uses thereof for the treatment of immune diseases | |
ZA201700165B (en) | Influenza virus vaccines and uses thereof | |
IL263846B (en) | Formulation of a peptide vaccine | |
EP3471767A4 (en) | Influenza virus hemagglutinin proteins and uses thereof | |
PH12016502500A1 (en) | Influenza virus vaccines and uses thereof | |
EP3133933C0 (en) | Assembly of at least one plant protein and at least one milk protein, production thereof and uses of same | |
EP3528827A4 (en) | Influenza hemagglutinin protein vaccines | |
HK1259146A1 (en) | Methods and compositions for influenza vaccination | |
EP3547850A4 (en) | Stevia plant and uses thereof | |
IL312520A (en) | Modification of engineered influenza hemagglutinin polypeptides | |
IL279719A (en) | Influenza virus hemagglutinin mutants | |
HUE062956T2 (en) | Processes for the preparation of niraparib and intermediates thereof | |
EP3562498A4 (en) | Influenza vaccines | |
GB201610714D0 (en) | Spray head | |
HK1249864A1 (en) | Modified h7 hemaggluttinin glycoprotein of the influenza a/shanghai/2/2013 h7 sequence | |
GB201604071D0 (en) | Spray head | |
GB201516547D0 (en) | Modified spray head | |
PL3443247T3 (en) | Valve nozzle and valve nozzle assembly | |
ZA201903341B (en) | Pharmaceutical compositions and uses thereof | |
ZAA201800998S (en) | Perfume bottle | |
AU201711870S (en) | Perfume bottle | |
IL249705A0 (en) | Influenza virus vaccines and uses thereof |