JP2007537258A5 - - Google Patents
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- Publication number
- JP2007537258A5 JP2007537258A5 JP2007513239A JP2007513239A JP2007537258A5 JP 2007537258 A5 JP2007537258 A5 JP 2007537258A5 JP 2007513239 A JP2007513239 A JP 2007513239A JP 2007513239 A JP2007513239 A JP 2007513239A JP 2007537258 A5 JP2007537258 A5 JP 2007537258A5
- Authority
- JP
- Japan
- Prior art keywords
- component
- amount
- volume
- cremophor
- propylene glycol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims 27
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical group CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 12
- 239000008389 polyethoxylated castor oil Substances 0.000 claims 11
- 238000009472 formulation Methods 0.000 claims 10
- 239000000203 mixture Substances 0.000 claims 10
- 239000003186 pharmaceutical solution Substances 0.000 claims 10
- 229920002685 Polyoxyl 35CastorOil Polymers 0.000 claims 9
- QUANRIQJNFHVEU-UHFFFAOYSA-N oxirane;propane-1,2,3-triol Chemical group C1CO1.OCC(O)CO QUANRIQJNFHVEU-UHFFFAOYSA-N 0.000 claims 9
- 239000003981 vehicle Substances 0.000 claims 9
- 238000000034 method Methods 0.000 claims 8
- AYUNIORJHRXIBJ-TXHRRWQRSA-N tanespimycin Chemical compound N1C(=O)\C(C)=C\C=C/[C@H](OC)[C@@H](OC(N)=O)\C(C)=C\[C@H](C)[C@@H](O)[C@@H](OC)C[C@H](C)CC2=C(NCC=C)C(=O)C=C1C2=O AYUNIORJHRXIBJ-TXHRRWQRSA-N 0.000 claims 7
- 229950007866 tanespimycin Drugs 0.000 claims 7
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims 6
- 229920002556 Polyethylene Glycol 300 Polymers 0.000 claims 2
- 229920002565 Polyethylene Glycol 400 Polymers 0.000 claims 2
- JLFNLZLINWHATN-UHFFFAOYSA-N pentaethylene glycol Chemical compound OCCOCCOCCOCCOCCO JLFNLZLINWHATN-UHFFFAOYSA-N 0.000 claims 2
- 238000003756 stirring Methods 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 1
- 238000001914 filtration Methods 0.000 claims 1
- 239000004615 ingredient Substances 0.000 claims 1
- 238000002360 preparation method Methods 0.000 claims 1
- 239000000243 solution Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US57021504P | 2004-05-11 | 2004-05-11 | |
| US11/123,570 US20050256097A1 (en) | 2004-05-11 | 2005-05-05 | Pharmaceutical solution formulations containing 17-AAG |
| PCT/US2005/016010 WO2005110398A2 (en) | 2004-05-11 | 2005-05-06 | Pharmaceutical solution formulations containing 17-aag |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007537258A JP2007537258A (ja) | 2007-12-20 |
| JP2007537258A5 true JP2007537258A5 (https=) | 2008-06-19 |
Family
ID=35310196
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007513239A Abandoned JP2007537258A (ja) | 2004-05-11 | 2005-05-06 | 17−aagを含む医薬溶液製剤 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20050256097A1 (https=) |
| EP (1) | EP1744743A2 (https=) |
| JP (1) | JP2007537258A (https=) |
| AU (1) | AU2005244115A1 (https=) |
| BR (1) | BRPI0511036A (https=) |
| CA (1) | CA2565583A1 (https=) |
| IL (1) | IL178689A0 (https=) |
| MX (1) | MXPA06012935A (https=) |
| RU (1) | RU2382643C2 (https=) |
| WO (1) | WO2005110398A2 (https=) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090197852A9 (en) * | 2001-08-06 | 2009-08-06 | Johnson Robert G Jr | Method of treating breast cancer using 17-AAG or 17-AG or a prodrug of either in combination with a HER2 inhibitor |
| CA2563533C (en) | 2004-04-15 | 2013-10-01 | Shmuel A. Ben-Sasson | Compositions capable of facilitating penetration across a biological barrier |
| MX2007013494A (es) * | 2005-04-29 | 2008-01-24 | Kosan Biosciences Inc | Metodo para tratar mieloma multiple utilizando 17-aag o 17-ag o un profarmaco de ya sea 17-aag o 17-ag. |
| KR20080007642A (ko) * | 2005-04-29 | 2008-01-22 | 코산 바이오사이언시즈, 인코포레이티드 | 프로테아좀 억제제와 함께 17-aag 또는 17-ag 또는 둘중 하나의 전구약물을 사용하여 다발성 골수종을 치료하는방법 |
| US7648976B2 (en) * | 2005-11-23 | 2010-01-19 | Bristol-Myers Squibb Company | 17-allylamino-17-demethoxygeldanamycin polymorphs and formulations |
| US20090042847A1 (en) * | 2005-11-23 | 2009-02-12 | Kosan Biosciences Incorporated | 17-allylamino-17-demethoxygeldanamycin polymorphs and formulations |
| US20070167422A1 (en) * | 2006-01-18 | 2007-07-19 | Yu Kwok S | Pharmaceutical compositions comprising 17-allylamino-17-demethoxygeldanamycin |
| WO2008044041A1 (en) | 2006-10-12 | 2008-04-17 | Astex Therapeutics Limited | Pharmaceutical combinations |
| EP2073807A1 (en) | 2006-10-12 | 2009-07-01 | Astex Therapeutics Limited | Pharmaceutical combinations |
| WO2008055386A1 (fr) * | 2006-11-10 | 2008-05-15 | Shenzhen Shengeryimei Biotech Co., Ltd. | Composition pharmaceutique hydrosoluble pour injection de 17-allyl amino-17-déméthoxy geldanamycine (17-aag) |
| PE20081506A1 (es) * | 2006-12-12 | 2008-12-09 | Infinity Discovery Inc | Formulaciones de ansamicina |
| EP2121957A4 (en) * | 2007-01-26 | 2010-11-10 | Kosan Biosciences Inc | MACROLACTAMES OBTAINED BY MODIFIED BIOSYNTHESIS |
| WO2009009067A2 (en) * | 2007-07-09 | 2009-01-15 | Kwon Glen S | Micelle encapsulation of theropeutic agents |
| CN101820917B (zh) * | 2007-10-08 | 2013-01-02 | 佛维雅制药股份有限公司 | 水性眼科配制剂 |
| US20090258869A1 (en) * | 2008-02-08 | 2009-10-15 | The Regents Of The University Of California | Methods and compounds for treatment or prevention of substance-related disorders |
| KR101814186B1 (ko) | 2008-09-17 | 2018-03-14 | 키아스마 인코포레이티드 | 약제학적 조성물 및 연관된 투여방법 |
| EP2480207B1 (en) | 2009-09-25 | 2016-11-09 | Wisconsin Alumni Research Foundation | Micelle encapsulation of therapeutic agents |
| AU2011227083B2 (en) * | 2010-03-18 | 2013-07-18 | Innopharma, Inc. | Stable bortezomib formulations |
| US8945627B2 (en) | 2011-05-05 | 2015-02-03 | Wisconsin Alumni Research Foundation | Micelles for the solubilization of gossypol |
| US10682415B2 (en) | 2013-07-22 | 2020-06-16 | Wisconsin Alumni Research Foundation | Thermogel formulation for combination drug delivery |
| WO2016094831A1 (en) * | 2014-12-11 | 2016-06-16 | University Of Utah Research Foundation | Bi-functional allosteric protein-drug molecules for targeted therapy |
| WO2016126830A1 (en) | 2015-02-03 | 2016-08-11 | Chiasma Inc. | Method of treating diseases |
| JP2018008922A (ja) * | 2015-08-04 | 2018-01-18 | わかもと製薬株式会社 | ステロイド白内障の予防及び治療 |
| US11141457B1 (en) | 2020-12-28 | 2021-10-12 | Amryt Endo, Inc. | Oral octreotide therapy and contraceptive methods |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US553153A (en) * | 1896-01-14 | Type-writing machine | ||
| US4261989A (en) * | 1979-02-19 | 1981-04-14 | Kaken Chemical Co. Ltd. | Geldanamycin derivatives and antitumor drug |
| US6262022B1 (en) * | 1992-06-25 | 2001-07-17 | Novartis Ag | Pharmaceutical compositions containing cyclosporin as the active agent |
| US5932556A (en) * | 1995-09-17 | 1999-08-03 | Tam; Robert C | Methods and compositions for regulation of CD28 expression |
| AU743024B2 (en) * | 1997-03-05 | 2002-01-17 | Sugen, Inc. | Formulations for hydrophobic pharmaceutical agents |
| US20030044434A1 (en) * | 1997-07-29 | 2003-03-06 | Ping Gao | Self-emulsifying formulation for lipophilic compounds |
| US6121323A (en) * | 1997-12-03 | 2000-09-19 | 3M Innovative Properties Company | Bishydroxyureas |
| US5925776A (en) * | 1997-12-24 | 1999-07-20 | Schein Pharmacetical, Inc. | Polyethoxylated castor oil, process of making the same and formulations thereof |
| US6682758B1 (en) * | 1998-12-22 | 2004-01-27 | The United States Of America As Represented By The Department Of Health And Human Services | Water-insoluble drug delivery system |
| AU773618B2 (en) * | 1998-12-22 | 2004-05-27 | United States Of America, Represented By The Secretary, Department Of Health And Human Services, The | Water-insoluble drug delivery system |
| TW471968B (en) * | 1999-08-25 | 2002-01-11 | Committee On Chinese Medicine | Solamargine pharmaceutical composition for killing cancer cells |
| US20020037855A1 (en) * | 2000-05-05 | 2002-03-28 | Fritz Stanislaus | Stabilized medicament containing cysteinyl derivatives |
| ATE526019T1 (de) * | 2000-07-28 | 2011-10-15 | Sloan Kettering Inst Cancer | Verfahren zur behandlung von zellproliferationen störungen und virusinfektionen |
| DE60132103T2 (de) * | 2000-10-31 | 2008-04-17 | Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield | Perorale, selbst-emulgierende darreichungsformen von pyranon-proteaseinhibitoren |
| US7025992B2 (en) * | 2001-02-14 | 2006-04-11 | Gw Pharma Limited | Pharmaceutical formulations |
| DK1373215T3 (da) * | 2001-03-30 | 2006-11-13 | Us Health | Gelanamycinderivater egnet til behandling af cancer |
| WO2002092076A1 (en) * | 2001-05-16 | 2002-11-21 | Cytovia, Inc. | Substituted coumarins and quinolines as caspases activators |
| US6962944B2 (en) * | 2001-07-31 | 2005-11-08 | Arqule, Inc. | Pharmaceutical compositions containing beta-lapachone, or derivatives or analogs thereof, and methods of using same |
| US6872715B2 (en) * | 2001-08-06 | 2005-03-29 | Kosan Biosciences, Inc. | Benzoquinone ansamycins |
| US6653319B1 (en) * | 2001-08-10 | 2003-11-25 | University Of Kentucky Research Foundation | Pharmaceutical formulation for poorly water soluble camptothecin analogues |
| US8071133B2 (en) * | 2001-08-20 | 2011-12-06 | Stiefel Laboratories, Inc. | Oral dosage forms of water insoluble drugs and methods of making the same |
| IL160761A0 (en) * | 2001-10-19 | 2004-08-31 | Isotechnika Inc | Novel cyclosporin analog microemulsion preconcentrates |
| KR20040066177A (ko) * | 2001-12-19 | 2004-07-23 | 알자 코포레이션 | 친수성 거대분자의 경구 생체이용률을 증가시키기 위한제형 및 투여 형태 |
| CA2471081A1 (en) * | 2001-12-19 | 2003-07-03 | Alza Corporation | Formulation & dosage form for the controlled delivery of therapeutic agents |
| US6803046B2 (en) * | 2002-08-16 | 2004-10-12 | Bracco International B.V. | Sincalide formulations |
| US7649006B2 (en) * | 2002-08-23 | 2010-01-19 | Sloan-Kettering Institute For Cancer Research | Synthesis of epothilones, intermediates thereto and analogues thereof |
-
2005
- 2005-05-05 US US11/123,570 patent/US20050256097A1/en not_active Abandoned
- 2005-05-06 AU AU2005244115A patent/AU2005244115A1/en not_active Abandoned
- 2005-05-06 CA CA002565583A patent/CA2565583A1/en not_active Abandoned
- 2005-05-06 WO PCT/US2005/016010 patent/WO2005110398A2/en not_active Ceased
- 2005-05-06 MX MXPA06012935A patent/MXPA06012935A/es active IP Right Grant
- 2005-05-06 EP EP05779076A patent/EP1744743A2/en not_active Withdrawn
- 2005-05-06 RU RU2006143666/15A patent/RU2382643C2/ru not_active IP Right Cessation
- 2005-05-06 JP JP2007513239A patent/JP2007537258A/ja not_active Abandoned
- 2005-05-06 BR BRPI0511036-0A patent/BRPI0511036A/pt not_active IP Right Cessation
-
2006
- 2006-10-17 IL IL178689A patent/IL178689A0/en unknown
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