DK1373215T3 - Gelanamycinderivater egnet til behandling af cancer - Google Patents

Gelanamycinderivater egnet til behandling af cancer

Info

Publication number
DK1373215T3
DK1373215T3 DK02757908T DK02757908T DK1373215T3 DK 1373215 T3 DK1373215 T3 DK 1373215T3 DK 02757908 T DK02757908 T DK 02757908T DK 02757908 T DK02757908 T DK 02757908T DK 1373215 T3 DK1373215 T3 DK 1373215T3
Authority
DK
Denmark
Prior art keywords
cancer
gelanamycin
treatment
derivatives suitable
host
Prior art date
Application number
DK02757908T
Other languages
English (en)
Inventor
Melinda G Hollingshead
Edward A Sausville
B Rao Vishnuvajjala
Kenneth M Snader
Original Assignee
Us Health
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Us Health filed Critical Us Health
Application granted granted Critical
Publication of DK1373215T3 publication Critical patent/DK1373215T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D225/00—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom
    • C07D225/04—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D225/06—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
DK02757908T 2001-03-30 2002-03-28 Gelanamycinderivater egnet til behandling af cancer DK1373215T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US28007801P 2001-03-30 2001-03-30

Publications (1)

Publication Number Publication Date
DK1373215T3 true DK1373215T3 (da) 2006-11-13

Family

ID=23071560

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02757908T DK1373215T3 (da) 2001-03-30 2002-03-28 Gelanamycinderivater egnet til behandling af cancer

Country Status (19)

Country Link
US (1) US6890917B2 (da)
EP (1) EP1373215B1 (da)
JP (1) JP4213472B2 (da)
KR (1) KR100831133B1 (da)
CN (1) CN1262542C (da)
AT (1) ATE334119T1 (da)
AU (1) AU2002307020B2 (da)
CA (1) CA2430692C (da)
CY (1) CY1107484T1 (da)
DE (1) DE60213386T2 (da)
DK (1) DK1373215T3 (da)
ES (1) ES2268068T3 (da)
IL (2) IL156122A0 (da)
MX (1) MXPA03007856A (da)
NZ (1) NZ526133A (da)
PT (1) PT1373215E (da)
SI (1) SI21369A (da)
WO (1) WO2002079167A1 (da)
ZA (1) ZA200304178B (da)

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KR20080007642A (ko) * 2005-04-29 2008-01-22 코산 바이오사이언시즈, 인코포레이티드 프로테아좀 억제제와 함께 17-ａａｇ 또는 17-ａｇ 또는 둘중 하나의 전구약물을 사용하여 다발성 골수종을 치료하는방법
JP2008543941A (ja) * 2005-06-21 2008-12-04 インフィニティ・ディスカバリー・インコーポレイテッド アンサマイシン製剤およびその使用方法
WO2007059116A2 (en) * 2005-11-14 2007-05-24 Abraxis Bioscience, Inc. Geldanamycin derivatives and pharmaceutical compositions thereof
US7648976B2 (en) * 2005-11-23 2010-01-19 Bristol-Myers Squibb Company 17-allylamino-17-demethoxygeldanamycin polymorphs and formulations
US20090042847A1 (en) * 2005-11-23 2009-02-12 Kosan Biosciences Incorporated 17-allylamino-17-demethoxygeldanamycin polymorphs and formulations
US20070167422A1 (en) * 2006-01-18 2007-07-19 Yu Kwok S Pharmaceutical compositions comprising 17-allylamino-17-demethoxygeldanamycin
US20070207992A1 (en) * 2006-02-21 2007-09-06 Board Of Trustees Of Michigan State University Geldanamycin derivatives and method of use thereof
CN100519536C (zh) * 2006-03-21 2009-07-29 中国医学科学院医药生物技术研究所 一组连有核苷碱基的格尔德霉素衍生物
US20070293451A1 (en) * 2006-05-02 2007-12-20 University Of Pittsburgh Regulation ao ApoB by Hsp110 proteins and related compositions and methods
KR100796637B1 (ko) * 2006-09-29 2008-01-22 한국생명공학연구원 젤다나마이신 유도체, 이의 약학적으로 허용가능한 염,이의 제조방법 및 이를 유효성분으로 함유하는 암 예방 및치료제
CN100500668C (zh) * 2006-12-19 2009-06-17 中国人民解放军军事医学科学院毒物药物研究所 格尔德霉素衍生物及其制备方法和制备药物的用途
CN101688227B (zh) 2007-01-26 2013-07-24 科森生物科学公司 通过工程化生物合成制备的大环内酰胺
US8303960B2 (en) * 2007-02-27 2012-11-06 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Radiolabeled affibody molecules
WO2008116216A1 (en) * 2007-03-22 2008-09-25 Medical College Of Georgia Research Institute, Inc. Compositions and methods for inhibiting cancer metastasis
WO2008128063A1 (en) * 2007-04-12 2008-10-23 Infinity Discovery, Inc. Hydroquinone ansamycin formulations
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US20090186039A1 (en) * 2008-01-18 2009-07-23 Jang Sung-Key Novel use of grp 94 in virus infection
US20090258869A1 (en) * 2008-02-08 2009-10-15 The Regents Of The University Of California Methods and compounds for treatment or prevention of substance-related disorders
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JPWO2011040421A1 (ja) 2009-09-29 2013-02-28 武田薬品工業株式会社 スクリーニング方法
CN102030764B (zh) * 2010-11-12 2012-07-04 中国医学科学院医药生物技术研究所 4，5双氢噻嗪酮格尔德霉素及其制备方法
WO2012082765A2 (en) 2010-12-16 2012-06-21 The United State Of America. As Represented By The Secretary Department Of Health And Human Services Methods for decreasing body weight and treating diabetes
CN102603635B (zh) * 2011-01-21 2016-08-03 杭州华东医药集团生物工程研究所有限公司 格尔德霉素衍生物及其制备方法和用途
US8921533B2 (en) 2011-07-25 2014-12-30 Chromatin Technologies Glycosylated valproic acid analogs and uses thereof
WO2013074695A1 (en) 2011-11-14 2013-05-23 The Regents Of The University Of Colorado, A Body Corporate Hsp90 inhibitors with modified toxicity
CN102552150B (zh) * 2012-03-02 2013-10-30 首都医科大学 一种格尔德霉素脂质体的制备及应用
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Also Published As

Publication number Publication date
ATE334119T1 (de) 2006-08-15
CA2430692C (en) 2011-05-31
CY1107484T1 (el) 2013-03-13
CN1262542C (zh) 2006-07-05
CN1484639A (zh) 2004-03-24
ES2268068T3 (es) 2007-03-16
IL156122A0 (en) 2003-12-23
JP4213472B2 (ja) 2009-01-21
EP1373215B1 (en) 2006-07-26
US20040053909A1 (en) 2004-03-18
EP1373215A1 (en) 2004-01-02
DE60213386D1 (de) 2006-09-07
DE60213386T2 (de) 2006-11-23
SI21369A (sl) 2004-06-30
KR20040023581A (ko) 2004-03-18
PT1373215E (pt) 2006-12-29
MXPA03007856A (es) 2003-12-04
IL156122A (en) 2010-11-30
WO2002079167A1 (en) 2002-10-10
NZ526133A (en) 2005-08-26
ZA200304178B (en) 2004-02-17
US6890917B2 (en) 2005-05-10
CA2430692A1 (en) 2002-10-10
JP2004519514A (ja) 2004-07-02
AU2002307020B2 (en) 2007-06-28
KR100831133B1 (ko) 2008-05-20

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