|
US4335127A
(en)
|
1979-01-08 |
1982-06-15 |
Janssen Pharmaceutica, N.V. |
Piperidinylalkyl quinazoline compounds, composition and method of use
|
|
KR910006138B1
(ko)
|
1986-09-30 |
1991-08-16 |
에자이 가부시끼가이샤 |
환상아민 유도체
|
|
US4921863A
(en)
|
1988-02-17 |
1990-05-01 |
Eisai Co., Ltd. |
Cyclic amine derivatives
|
|
US5721237A
(en)
|
1991-05-10 |
1998-02-24 |
Rhone-Poulenc Rorer Pharmaceuticals Inc. |
Protein tyrosine kinase aryl and heteroaryl quinazoline compounds having selective inhibition of HER-2 autophosphorylation properties
|
|
AU661533B2
(en)
|
1992-01-20 |
1995-07-27 |
Astrazeneca Ab |
Quinazoline derivatives
|
|
GB9510757D0
(en)
|
1994-09-19 |
1995-07-19 |
Wellcome Found |
Therapeuticaly active compounds
|
|
MX9707453A
(es)
|
1995-03-30 |
1997-12-31 |
Pfizer |
Derivados de quinazolina.
|
|
GB9508535D0
(en)
|
1995-04-27 |
1995-06-14 |
Zeneca Ltd |
Quinazoline derivative
|
|
GB9508538D0
(en)
|
1995-04-27 |
1995-06-14 |
Zeneca Ltd |
Quinazoline derivatives
|
|
GB9508537D0
(en)
|
1995-04-27 |
1995-06-14 |
Zeneca Ltd |
Quinazoline derivatives
|
|
WO1996033977A1
(en)
|
1995-04-27 |
1996-10-31 |
Zeneca Limited |
Quinazoline derivatives
|
|
GB9508565D0
(en)
|
1995-04-27 |
1995-06-14 |
Zeneca Ltd |
Quiazoline derivative
|
|
US5747498A
(en)
|
1996-05-28 |
1998-05-05 |
Pfizer Inc. |
Alkynyl and azido-substituted 4-anilinoquinazolines
|
|
GB9514265D0
(en)
|
1995-07-13 |
1995-09-13 |
Wellcome Found |
Hetrocyclic compounds
|
|
BR9707495A
(pt)
|
1996-02-13 |
1999-07-27 |
Zeneca Ltd |
Derivado de quinazolina processo para a preparação do mesmo composição farmacêutica e processo para a produç o de um efeito antiangiogênico e/ou de redução de permeabilidade vascular em um animal de sangue quente
|
|
GB9603095D0
(en)
|
1996-02-14 |
1996-04-10 |
Zeneca Ltd |
Quinazoline derivatives
|
|
HU228446B1
(en)
|
1996-04-12 |
2013-03-28 |
Warner Lambert Co |
Kinazoline derivatives as irreversible inhibitors of protein-kinase, pharmaceutical compositions containing these compounds and use thereof
|
|
GB9607729D0
(en)
|
1996-04-13 |
1996-06-19 |
Zeneca Ltd |
Quinazoline derivatives
|
|
ID19609A
(id)
|
1996-07-13 |
1998-07-23 |
Glaxo Group Ltd |
Senyawa-senyawa heterosiklik
|
|
GB9718972D0
(en)
|
1996-09-25 |
1997-11-12 |
Zeneca Ltd |
Chemical compounds
|
|
EP0837063A1
(en)
|
1996-10-17 |
1998-04-22 |
Pfizer Inc. |
4-Aminoquinazoline derivatives
|
|
ZA986732B
(en)
|
1997-07-29 |
1999-02-02 |
Warner Lambert Co |
Irreversible inhibitiors of tyrosine kinases
|
|
GB9800575D0
(en)
*
|
1998-01-12 |
1998-03-11 |
Glaxo Group Ltd |
Heterocyclic compounds
|
|
WO2000009481A1
(en)
|
1998-08-11 |
2000-02-24 |
Takeda Chemical Industries, Ltd. |
Cyclic amide compounds, process for producing the same, intermediates thereof and herbicides
|
|
US6297258B1
(en)
|
1998-09-29 |
2001-10-02 |
American Cyanamid Company |
Substituted 3-cyanoquinolines
|
|
BR9914164A
(pt)
|
1998-09-29 |
2001-06-26 |
American Cyanamid Co |
Composto, método para o tratamento, inibição do crescimento de, ou erradiacação de um neoplasma, e de doença de rim policìstico, em um mamìfero em necessidade do mesmo, composição farmacêutica, e, processo para preparar um composto
|
|
ATE232205T1
(de)
|
1998-10-01 |
2003-02-15 |
Astrazeneca Ab |
Chinolin- und chinazolin derivate und ihre verwendung als inhibitoren von krankheiten, bei denen cytokine beteiligt wird
|
|
TW575567B
(en)
|
1998-10-23 |
2004-02-11 |
Akzo Nobel Nv |
Serine protease inhibitor
|
|
UA71945C2
(en)
|
1999-01-27 |
2005-01-17 |
Pfizer Prod Inc |
Substituted bicyclic derivatives being used as anticancer agents
|
|
TR200102505T2
(tr)
|
1999-02-27 |
2003-01-21 |
Boehringer Ingelheim Pharma Kg |
4-amino-kinazolin ve kinolin türevleri.
|
|
DE19911509A1
(de)
|
1999-03-15 |
2000-09-21 |
Boehringer Ingelheim Pharma |
Bicyclische Heterocyclen, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Verfahren zu ihrer Herstellung
|
|
US6258820B1
(en)
|
1999-03-19 |
2001-07-10 |
Parker Hughes Institute |
Synthesis and anti-tumor activity of 6,7-dialkoxy-4-phenylamino-quinazolines
|
|
EE04748B1
(et)
|
1999-06-21 |
2006-12-15 |
Boehringer Ingelheim Pharma Kg |
Bitsüklilised heterotsüklilised ühendid, neid ühendeid sisaldavad ravimid, nende kasutamine ja meetodid nende valmistamiseks
|
|
US6806274B1
(en)
|
1999-07-07 |
2004-10-19 |
Astrazeneca Uk Limited |
Quinazoline derivatives
|
|
GB9917408D0
(en)
|
1999-07-23 |
1999-09-22 |
Smithkline Beecham Plc |
Compounds
|
|
US7709479B1
(en)
|
1999-09-21 |
2010-05-04 |
Astrazeneca |
Quinazoline derivatives and their use as pharmaceuticals
|
|
GB9922171D0
(en)
|
1999-09-21 |
1999-11-17 |
Zeneca Ltd |
Chemical compounds
|
|
CZ301689B6
(cs)
|
1999-11-05 |
2010-05-26 |
Astrazeneca Ab |
Derivát chinazolinu a farmaceutický prostredek, který ho obsahuje
|
|
AU2001235804A1
(en)
|
2000-03-06 |
2001-09-17 |
Astrazeneca Ab |
Therapy
|
|
UA73993C2
(uk)
|
2000-06-06 |
2005-10-17 |
Астразенека Аб |
Хіназолінові похідні для лікування пухлин та фармацевтична композиція
|
|
HRP20021005A2
(en)
|
2000-06-22 |
2004-02-29 |
Pfizer Prod Inc |
Substituted bicyclic derivatives for the treatment of abnormal cell growth
|
|
WO2002002534A1
(en)
|
2000-07-03 |
2002-01-10 |
Astrazeneca Ab |
Quinazolines with therapeutic use
|
|
CZ2003243A3
(cs)
|
2000-07-26 |
2003-09-17 |
Smithkline Beecham P. L. C. |
Aminopiperidinové chinoliny a jejich azaisosterické analogy s antibakteriální aktivitou
|
|
DE10040527A1
(de)
|
2000-08-18 |
2002-02-28 |
Boehringer Ingelheim Pharma |
Chinazoline und Verfahren zu ihrer Herstellung
|
|
CA2419301C
(en)
|
2000-08-21 |
2009-12-08 |
Astrazeneca Ab |
Quinazoline derivatives
|
|
DE10042059A1
(de)
|
2000-08-26 |
2002-03-07 |
Boehringer Ingelheim Pharma |
Bicyclische Heterocyclen, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Verfahren zu ihrer Herstellung
|
|
US6617329B2
(en)
|
2000-08-26 |
2003-09-09 |
Boehringer Ingelheim Pharma Kg |
Aminoquinazolines and their use as medicaments
|
|
US20020082270A1
(en)
|
2000-08-26 |
2002-06-27 |
Frank Himmelsbach |
Aminoquinazolines which inhibit signal transduction mediated by tyrosine kinases
|
|
EP1719770A3
(en)
|
2000-09-21 |
2008-03-05 |
Smithkline Beecham Plc |
Quinoline derivatives as antibacterials
|
|
US6849625B2
(en)
|
2000-10-13 |
2005-02-01 |
Astrazeneca Ab |
Quinazoline derivatives with anti-tumour activity
|
|
US20040063733A1
(en)
|
2000-10-25 |
2004-04-01 |
Lambert Christine Marie Paul |
Quinazoline derivatives
|
|
EP1337524A1
(en)
|
2000-11-02 |
2003-08-27 |
AstraZeneca AB |
Substituted quinolines as antitumor agents
|
|
ATE369894T1
(de)
|
2000-11-22 |
2007-09-15 |
Novartis Pharma Gmbh |
Kombination enthaltend ein mittel zur verminderung von vegf-aktivität und ein mittel zur verminderung von egf-aktivität
|
|
AUPR201600A0
(en)
|
2000-12-11 |
2001-01-11 |
Fujisawa Pharmaceutical Co., Ltd. |
Quinazolinone derivative
|
|
GB0101577D0
(en)
|
2001-01-22 |
2001-03-07 |
Smithkline Beecham Plc |
Compounds
|
|
WO2002062767A1
(en)
|
2001-02-07 |
2002-08-15 |
Sumitomo Pharmaceuticals Company, Limited |
Novel quinazoline derivatives
|
|
NZ516873A
(en)
|
2001-02-12 |
2003-11-28 |
Warner Lambert Co |
Compositions containing retinoids and erb inhibitors and their use in inhibiting retinoid skin damage
|
|
EP1369418B1
(en)
|
2001-02-21 |
2010-07-28 |
Mitsubishi Tanabe Pharma Corporation |
Quinazoline derivatives
|
|
PL364625A1
(en)
|
2001-02-23 |
2004-12-13 |
Merck & Co, Inc. |
N-substituted nonaryl-heterocyclic nmda/nr2b antagonists
|
|
US6562319B2
(en)
|
2001-03-12 |
2003-05-13 |
Yissum Research Development Company Of The Hebrew University Of Jerusalem |
Radiolabeled irreversible inhibitors of epidermal growth factor receptor tyrosine kinase and their use in radioimaging and radiotherapy
|
|
US20030125344A1
(en)
|
2001-03-23 |
2003-07-03 |
Bayer Corporation |
Rho-kinase inhibitors
|
|
WO2002092577A1
(en)
|
2001-05-14 |
2002-11-21 |
Astrazeneca Ab |
Quinazoline derivatives
|
|
WO2002092578A1
(en)
|
2001-05-14 |
2002-11-21 |
Astrazeneca Ab |
Quinazoline derivatives
|
|
JPWO2002094790A1
(ja)
|
2001-05-23 |
2004-09-09 |
三菱ウェルファーマ株式会社 |
縮合ヘテロ環化合物およびその医薬用途
|
|
CA2349044A1
(en)
|
2001-05-28 |
2002-11-28 |
Optenia, Inc. |
Method of polarisation compensation in grating-and phasar-based devices by using overlayer deposited on the compensating region to modify local slab waveguide birefringence
|
|
GB0126433D0
(en)
|
2001-11-03 |
2002-01-02 |
Astrazeneca Ab |
Compounds
|
|
JP2005515176A
(ja)
|
2001-11-03 |
2005-05-26 |
アストラゼネカ アクチボラグ |
抗腫瘍剤としてのキナゾリン誘導体
|
|
PL373848A1
(en)
|
2001-12-12 |
2005-09-19 |
Pfizer Products Inc. |
Quinazoline derivatives for the treatment of abnormal cell growth
|
|
TWI324597B
(en)
|
2002-03-28 |
2010-05-11 |
Astrazeneca Ab |
Quinazoline derivatives
|
|
US6924285B2
(en)
|
2002-03-30 |
2005-08-02 |
Boehringer Ingelheim Pharma Gmbh & Co. |
Bicyclic heterocyclic compounds, pharmaceutical compositions containing these compounds, their use and process for preparing them
|
|
CA2476008C
(en)
|
2002-03-30 |
2011-12-13 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Bicyclic heterocyclic compounds, pharmaceutical compositions containing these compounds, their use and process for preparing them
|
|
JP2006515871A
(ja)
|
2003-01-23 |
2006-06-08 |
ティー.ケイ. シグナル リミテッド |
上皮増殖因子受容体チロシンキナーゼの不可逆阻害剤ならびにその使用
|
|
GB0309009D0
(en)
|
2003-04-22 |
2003-05-28 |
Astrazeneca Ab |
Quinazoline derivatives
|
|
GB0309850D0
(en)
|
2003-04-30 |
2003-06-04 |
Astrazeneca Ab |
Quinazoline derivatives
|
|
JP2007500177A
(ja)
|
2003-07-29 |
2007-01-11 |
アストラゼネカ アクチボラグ |
チロシンキナーゼ阻害剤としてのピペリジルキナゾリン誘導体
|
|
GB0317665D0
(en)
|
2003-07-29 |
2003-09-03 |
Astrazeneca Ab |
Qinazoline derivatives
|
|
GB0318423D0
(en)
|
2003-08-06 |
2003-09-10 |
Astrazeneca Ab |
Chemical compounds
|
|
GB0321648D0
(en)
|
2003-09-16 |
2003-10-15 |
Astrazeneca Ab |
Quinazoline derivatives
|
|
AU2004272345A1
(en)
|
2003-09-16 |
2005-03-24 |
Astrazeneca Ab |
Quinazoline derivatives
|
|
AU2004272346A1
(en)
|
2003-09-16 |
2005-03-24 |
Astrazeneca Ab |
Quinazoline derivatives
|
|
US20070032508A1
(en)
|
2003-09-16 |
2007-02-08 |
Bradbury Robert H |
Quinazoline derivatives as tyrosine kinase inhibitors
|
|
ES2305844T3
(es)
|
2003-09-16 |
2008-11-01 |
Astrazeneca Ab |
Derivados de quinazolina como inhibidores de tirosina cinasa.
|
|
CN1882570B
(zh)
|
2003-09-19 |
2010-12-08 |
阿斯利康(瑞典)有限公司 |
喹唑啉衍生物
|
|
WO2005028469A1
(en)
|
2003-09-19 |
2005-03-31 |
Astrazeneca Ab |
Quinazoline derivatives
|
|
KR20060100388A
(ko)
|
2003-09-25 |
2006-09-20 |
아스트라제네카 아베 |
퀴나졸린 유도체
|
|
GB0322409D0
(en)
|
2003-09-25 |
2003-10-29 |
Astrazeneca Ab |
Quinazoline derivatives
|
|
GB0326459D0
(en)
|
2003-11-13 |
2003-12-17 |
Astrazeneca Ab |
Quinazoline derivatives
|
|
AU2005250224A1
(en)
|
2004-06-04 |
2005-12-15 |
Astrazeneca Ab |
Quinazoline derivatives as ERBB receptor tyrosine kinases
|
|
EP1838712B8
(en)
|
2004-12-14 |
2011-10-12 |
AstraZeneca AB |
Pyrazolopyrimidine compounds as antitumor agents
|
|
MX2007010399A
(es)
|
2005-02-26 |
2007-09-25 |
Astrazeneca Ab |
Derivados de quinazolina en la forma de inhibidores de cinasa de tirosina.
|
|
GB0504475D0
(en)
|
2005-03-04 |
2005-04-13 |
Astrazeneca Ab |
Chemical compounds
|
|
GB0504474D0
(en)
|
2005-03-04 |
2005-04-13 |
Astrazeneca Ab |
Chemical compounds
|
|
GB0508717D0
(en)
|
2005-04-29 |
2005-06-08 |
Astrazeneca Ab |
Chemical compounds
|
|
GB0508715D0
(en)
|
2005-04-29 |
2005-06-08 |
Astrazeneca Ab |
Chemical compounds
|
|
WO2007034144A1
(en)
|
2005-09-20 |
2007-03-29 |
Astrazeneca Ab |
4- (ih-indazol-s-yl-amino)-quinazoline compounds as erbb receptor tyrosine kinase inhibitors for the treatment of cancer
|
|
JP2009508917A
(ja)
|
2005-09-20 |
2009-03-05 |
アストラゼネカ アクチボラグ |
抗癌剤としてのキナゾリン誘導体
|
|
JP2009517450A
(ja)
|
2005-12-02 |
2009-04-30 |
アストラゼネカ アクチボラグ |
チロシンキナーゼ阻害薬としての4−アニリノ置換キナゾリン誘導体
|
|
JP2009517451A
(ja)
|
2005-12-02 |
2009-04-30 |
アストラゼネカ アクチボラグ |
Erbbチロシンキナーゼの阻害剤として使用されるキナゾリン誘導体
|