JP2007516189A5 - - Google Patents
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- Publication number
- JP2007516189A5 JP2007516189A5 JP2006518300A JP2006518300A JP2007516189A5 JP 2007516189 A5 JP2007516189 A5 JP 2007516189A5 JP 2006518300 A JP2006518300 A JP 2006518300A JP 2006518300 A JP2006518300 A JP 2006518300A JP 2007516189 A5 JP2007516189 A5 JP 2007516189A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- formula
- substituted
- process according
- derivative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0308354A FR2857361B1 (fr) | 2003-07-08 | 2003-07-08 | PREPARATION DE DERIVES DE 1,3-DIPHENYPROP-2-¼n-1-one |
| PCT/FR2004/001797 WO2005005369A1 (fr) | 2003-07-08 | 2004-07-08 | Preparation de derives de 1,3-diphenylprop-2-en-1-one |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007516189A JP2007516189A (ja) | 2007-06-21 |
| JP2007516189A5 true JP2007516189A5 (enExample) | 2007-08-02 |
Family
ID=33522868
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006518300A Pending JP2007516189A (ja) | 2003-07-08 | 2004-07-08 | １，３−ジフェニルプロパ−２−エン−１−オン誘導体の製造 |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US7385082B2 (enExample) |
| EP (1) | EP1644312B1 (enExample) |
| JP (1) | JP2007516189A (enExample) |
| KR (1) | KR20060030110A (enExample) |
| CN (1) | CN1819986B (enExample) |
| AT (1) | ATE468317T1 (enExample) |
| AU (1) | AU2004255905B2 (enExample) |
| BR (1) | BRPI0412370A (enExample) |
| CA (1) | CA2531443C (enExample) |
| DE (1) | DE602004027251D1 (enExample) |
| DK (1) | DK1644312T3 (enExample) |
| EA (1) | EA010410B1 (enExample) |
| ES (1) | ES2343803T3 (enExample) |
| FR (1) | FR2857361B1 (enExample) |
| IL (1) | IL172825A (enExample) |
| MX (1) | MXPA06000159A (enExample) |
| NO (1) | NO332411B1 (enExample) |
| NZ (1) | NZ544792A (enExample) |
| PL (1) | PL213226B1 (enExample) |
| SG (1) | SG129448A1 (enExample) |
| WO (1) | WO2005005369A1 (enExample) |
| ZA (1) | ZA200601040B (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2841784B1 (fr) | 2002-07-08 | 2007-03-02 | Composition a base de derives de 1,3-diphenylprop-2en-1-one substitues, preparation et utilisations | |
| FR2841900B1 (fr) * | 2002-07-08 | 2007-03-02 | Genfit S A | Nouveaux derives de 1,3-diphenylprop-2-en-1-one substitues, preparation et utilisations |
| TR201810393T4 (tr) | 2009-11-26 | 2018-08-27 | Genfit | Karaciğer rahatıszlıklarının tedavisi için 1,3-difenilprop-2-en-1-on türevlerinin kullanımı. |
| WO2011080276A1 (en) | 2009-12-29 | 2011-07-07 | Genfit | Pharmaceutical combinations comprising a dpp-4 inhibitor and a 1,3-diphenylprop-2-en-1-one derivative |
| MX2012013359A (es) | 2010-05-17 | 2013-02-11 | Genfit | Preparacion mejora de derivados de chalcona. |
| SG11201505281PA (en) * | 2013-01-18 | 2015-08-28 | Genfit | Methods of treatment of fibrosis and cancers |
| WO2017143038A1 (en) | 2016-02-16 | 2017-08-24 | Concert Pharmaceuticals, Inc. | Deuterated gft-505 |
| CN106674069B (zh) * | 2016-12-06 | 2018-05-11 | 上海博志研新药物技术有限公司 | Gft505及其中间体的制备方法 |
| CN110312705B (zh) * | 2017-01-22 | 2021-07-09 | 苏州科睿思制药有限公司 | Gft-505的晶型及其制备方法和用途 |
| AU2018223146B2 (en) | 2017-02-21 | 2023-12-21 | Genfit | Combination of a PPAR agonist with a FXR agonist |
| WO2019025017A1 (en) | 2017-08-04 | 2019-02-07 | Advitech Advisory And Technologies Sa | PROCESS FOR THE PREPARATION OF ELAFIBRANOR AND NEW SYNTHETIC INTERMEDIATES |
| US20200283381A1 (en) | 2017-11-16 | 2020-09-10 | Teva Pharmaceuticals International Gmbh | Solid state forms of elafibranor |
| CN109608318A (zh) * | 2019-01-31 | 2019-04-12 | 上海生农生化制品股份有限公司 | 一种戊唑醇中间体α的工业合成方法 |
| CN110156648A (zh) * | 2019-05-30 | 2019-08-23 | 河北科技大学 | 一种Elafibranor中间体的制备方法 |
| CN110143902B (zh) * | 2019-06-12 | 2021-06-04 | 天津科技大学 | 含硒查尔酮衍生物Compound 1和合成方法及在抗非酒精性脂肪肝炎药物中的应用 |
| CN110143890B (zh) * | 2019-06-12 | 2020-12-22 | 天津科技大学 | 一种查尔酮衍生物和合成方法及其在制备抗非酒精性脂肪肝炎药物中的应用 |
| US20230008367A1 (en) | 2019-09-26 | 2023-01-12 | Abionyx Pharma Sa | Compounds useful for treating liver diseases |
| CN113121394B (zh) * | 2019-12-30 | 2022-11-08 | 中国药科大学 | 一种苯氧乙酸类衍生物的制备方法 |
| BR112022023368A2 (pt) | 2020-05-18 | 2022-12-20 | Genfit | Elafibranor para o tratamento de colangite esclerosante primária |
| US20230301951A1 (en) | 2020-08-26 | 2023-09-28 | Genfit | Compositions and methods for the treatment of primary biliary cholangitis |
| WO2022189856A1 (en) | 2021-03-08 | 2022-09-15 | Abionyx Pharma Sa | Compounds useful for treating liver diseases |
| CN113230240B (zh) * | 2021-03-22 | 2022-12-27 | 广州医科大学 | 1,3-二苯基丙-2-烯-1-酮衍生物及其应用 |
| US20240216312A1 (en) | 2021-05-11 | 2024-07-04 | Genfit | Ppar-agonists for use in the treatment of liver failure |
| JP2024519337A (ja) | 2021-05-11 | 2024-05-10 | ジェンフィット | 敗血症の治療において使用するためのｐｐａｒのエラフィブラノール誘導体アゴニスト |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2359621C2 (de) * | 1973-11-30 | 1982-11-18 | Hoechst Ag, 6000 Frankfurt | Antiviral wirksame Alkalimetall- oder Ammoniumsalze der Polyacrylsäure |
| GB8426424D0 (en) * | 1984-10-19 | 1984-11-28 | Biorex Laboratories Ltd | Chalcone derivatives |
| JPH023670A (ja) * | 1988-06-22 | 1990-01-09 | Nippon Oil & Fats Co Ltd | アルキルチオカルコン誘導体 |
| JPH05255655A (ja) * | 1992-03-12 | 1993-10-05 | Kanebo Ltd | 紫外線吸収剤 |
| US5523302A (en) * | 1993-11-24 | 1996-06-04 | The Du Pont Merck Pharmaceutical Company | Aromatic compounds containing basic and acidic termini useful as fibrinogen receptor antagonists |
| EP0947511A1 (en) * | 1998-03-30 | 1999-10-06 | F. Hoffmann-La Roche Ag | Derivatives of phenoxy acetic acid and of phenoxymethyl tetrazole having antitumor activity |
| JPH11302243A (ja) * | 1998-04-24 | 1999-11-02 | Mitsubishi Chemical Corp | ジエチレントリアミン５酢酸誘導体 |
-
2003
- 2003-07-08 FR FR0308354A patent/FR2857361B1/fr not_active Expired - Fee Related
-
2004
- 2004-07-08 SG SG200700644A patent/SG129448A1/en unknown
- 2004-07-08 CN CN2004800195644A patent/CN1819986B/zh not_active Expired - Lifetime
- 2004-07-08 ES ES04767629T patent/ES2343803T3/es not_active Expired - Lifetime
- 2004-07-08 EP EP04767629A patent/EP1644312B1/fr not_active Expired - Lifetime
- 2004-07-08 DK DK04767629.1T patent/DK1644312T3/da active
- 2004-07-08 KR KR1020067000562A patent/KR20060030110A/ko not_active Ceased
- 2004-07-08 MX MXPA06000159A patent/MXPA06000159A/es active IP Right Grant
- 2004-07-08 DE DE602004027251T patent/DE602004027251D1/de not_active Expired - Lifetime
- 2004-07-08 AU AU2004255905A patent/AU2004255905B2/en not_active Ceased
- 2004-07-08 PL PL379543A patent/PL213226B1/pl unknown
- 2004-07-08 WO PCT/FR2004/001797 patent/WO2005005369A1/fr not_active Ceased
- 2004-07-08 NZ NZ544792A patent/NZ544792A/en not_active IP Right Cessation
- 2004-07-08 CA CA2531443A patent/CA2531443C/fr not_active Expired - Fee Related
- 2004-07-08 EA EA200600197A patent/EA010410B1/ru not_active IP Right Cessation
- 2004-07-08 BR BRPI0412370-0A patent/BRPI0412370A/pt not_active Application Discontinuation
- 2004-07-08 US US10/563,057 patent/US7385082B2/en not_active Expired - Lifetime
- 2004-07-08 AT AT04767629T patent/ATE468317T1/de active
- 2004-07-08 JP JP2006518300A patent/JP2007516189A/ja active Pending
-
2005
- 2005-12-26 IL IL172825A patent/IL172825A/en unknown
-
2006
- 2006-01-06 NO NO20060087A patent/NO332411B1/no not_active IP Right Cessation
- 2006-02-06 ZA ZA200601040A patent/ZA200601040B/en unknown
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