JP2007506792A5 - - Google Patents

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Publication number
JP2007506792A5
JP2007506792A5 JP2006528316A JP2006528316A JP2007506792A5 JP 2007506792 A5 JP2007506792 A5 JP 2007506792A5 JP 2006528316 A JP2006528316 A JP 2006528316A JP 2006528316 A JP2006528316 A JP 2006528316A JP 2007506792 A5 JP2007506792 A5 JP 2007506792A5
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JP
Japan
Prior art keywords
group
groups
acid
olefin
aromatic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2006528316A
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English (en)
Japanese (ja)
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JP2007506792A (ja
JP4874102B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2004/031816 external-priority patent/WO2005030150A2/en
Publication of JP2007506792A publication Critical patent/JP2007506792A/ja
Publication of JP2007506792A5 publication Critical patent/JP2007506792A5/ja
Application granted granted Critical
Publication of JP4874102B2 publication Critical patent/JP4874102B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

JP2006528316A 2003-09-25 2004-09-27 ９，１０−α，α−ＯＨ−タキサンアナログおよびその生成のための方法 Expired - Lifetime JP4874102B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US50668003P 2003-09-25 2003-09-25
US60/506,680 2003-09-25
PCT/US2004/031816 WO2005030150A2 (en) 2003-09-25 2004-09-27 9,10-α,α-OH-TAXANE ANALOGS AND METHODS FOR PRODUCTION THEREOF

Related Child Applications (2)

Application Number Title Priority Date Filing Date
JP2010200399A Division JP5525394B2 (ja) 2003-09-25 2010-09-07 ９，１０−α，α−ＯＨ−タキサンアナログおよびその生成のための方法
JP2011086840A Division JP5629632B2 (ja) 2003-09-25 2011-04-08 ９，１０−α，α−ＯＨ−タキサンアナログおよびその生成のための方法

Publications (3)

Publication Number Publication Date
JP2007506792A JP2007506792A (ja) 2007-03-22
JP2007506792A5 true JP2007506792A5 (enExample) 2010-10-28
JP4874102B2 JP4874102B2 (ja) 2012-02-15

Family

ID=34393186

Family Applications (5)

Application Number Title Priority Date Filing Date
JP2006528316A Expired - Lifetime JP4874102B2 (ja) 2003-09-25 2004-09-27 ９，１０−α，α−ＯＨ−タキサンアナログおよびその生成のための方法
JP2010200399A Expired - Lifetime JP5525394B2 (ja) 2003-09-25 2010-09-07 ９，１０−α，α−ＯＨ−タキサンアナログおよびその生成のための方法
JP2011086840A Expired - Lifetime JP5629632B2 (ja) 2003-09-25 2011-04-08 ９，１０−α，α−ＯＨ−タキサンアナログおよびその生成のための方法
JP2014141964A Expired - Lifetime JP6106634B2 (ja) 2003-09-25 2014-07-10 ９，１０−α，α−ＯＨ−タキサンアナログおよびその生成のための方法
JP2016137271A Expired - Lifetime JP6216417B2 (ja) 2003-09-25 2016-07-12 ９，１０−α，α−ＯＨ−タキサンアナログおよびその生成のための方法

Family Applications After (4)

Application Number Title Priority Date Filing Date
JP2010200399A Expired - Lifetime JP5525394B2 (ja) 2003-09-25 2010-09-07 ９，１０−α，α−ＯＨ−タキサンアナログおよびその生成のための方法
JP2011086840A Expired - Lifetime JP5629632B2 (ja) 2003-09-25 2011-04-08 ９，１０−α，α−ＯＨ−タキサンアナログおよびその生成のための方法
JP2014141964A Expired - Lifetime JP6106634B2 (ja) 2003-09-25 2014-07-10 ９，１０−α，α−ＯＨ−タキサンアナログおよびその生成のための方法
JP2016137271A Expired - Lifetime JP6216417B2 (ja) 2003-09-25 2016-07-12 ９，１０−α，α−ＯＨ−タキサンアナログおよびその生成のための方法

Country Status (14)

Country Link
US (8) US7745650B2 (enExample)
EP (2) EP1664033B1 (enExample)
JP (5) JP4874102B2 (enExample)
CN (1) CN1886400A (enExample)
AT (1) ATE377593T1 (enExample)
AU (1) AU2004275881A1 (enExample)
CA (1) CA2539975C (enExample)
DE (1) DE602004009943T2 (enExample)
DK (1) DK1664033T3 (enExample)
ES (1) ES2295937T3 (enExample)
HR (1) HRP20080057T3 (enExample)
PL (1) PL1664033T3 (enExample)
PT (1) PT1664033E (enExample)
WO (1) WO2005030150A2 (enExample)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2004275881A1 (en) 2003-09-25 2005-04-07 Tapestry Pharmaceuticals, Inc. 9,10-alpha,alpha-OH-taxane analogs and methods for production thereof
EP2634252B1 (en) 2005-02-11 2018-12-19 University of Southern California Method of expressing proteins with disulfide bridges
CA2634746A1 (en) * 2005-12-21 2007-07-05 Tapestry Pharmaceuticals, Inc. Processes for taxane derivatives and intermediates useful therein
US20090156828A1 (en) * 2005-12-21 2009-06-18 Tapestry Pharmaceuticals, Inc. Novel Compounds and Methods for Forming Taxanes and Using the Same
US20090306400A1 (en) * 2006-03-27 2009-12-10 Henri John T Convergent process for the synthesis of taxane derivatives.
US8008256B2 (en) * 2006-05-01 2011-08-30 University Of Southern California Combination therapy for treatment of cancer
WO2007143839A1 (en) * 2006-06-12 2007-12-21 6570763 Canada Inc. Semi-synthetic route for the preparation of paclitaxel, docetaxel and 10-deacetylbaccatin iii from 9-dihydro-13-acetylbaccatin iii
US7847111B2 (en) 2006-06-19 2010-12-07 Canada Inc. Semi-synthetic route for the preparation of paclitaxel, docetaxel, and 10-deacetylbaccatin III from 9-dihydro-13-acetylbaccatin III
US11786504B2 (en) 2006-09-28 2023-10-17 Tapestry Pharmaceuticals, Inc. Taxane analogs for the treatment of brain cancer
WO2008121476A1 (en) * 2007-03-28 2008-10-09 Tapestry Pharmaceuticals, Inc. Biologically active taxane analogs and methods of treatment by oral administration
US11873308B2 (en) 2006-11-06 2024-01-16 Tapestry Pharmaceuticals, Inc. Biologically active taxane analogs and methods of treatment by oral administration
US20080207743A1 (en) * 2007-02-28 2008-08-28 Rodger Lamb Biologically Active Taxane Analogs and Methods of Treatment
WO2008109360A1 (en) * 2007-02-28 2008-09-12 Tapestry Pharmaceuticals, Inc Taxane analogs for the treatment of brain cancer
US8802394B2 (en) 2008-11-13 2014-08-12 Radu O. Minea Method of expressing proteins with disulfide bridges with enhanced yields and activity
CN103764138A (zh) * 2011-04-07 2014-04-30 阿伯疗法责任有限公司 紫杉烷和Abeo-紫杉烷类似物
US9227983B2 (en) 2011-04-07 2016-01-05 Arbor Therapeutics, LLC Taxane and abeo-taxane analogs
KR101444693B1 (ko) * 2011-06-06 2014-09-26 아버 테라퓨틱스 엘엘씨 암 화학요법제의 산에 불안정한 친유성 전구약물
CA3174050A1 (en) 2020-03-04 2021-09-10 Aquedeon Medical, Inc. Vascular and aortic connectors with telescoping sheath and deployment methods thereof
US12622797B2 (en) 2021-03-04 2026-05-12 Aquedeon Medical, Inc. Vascular and aortic connectors with robotic delivery and deployment methods thereof

Family Cites Families (30)

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MX9102128A (es) * 1990-11-23 1992-07-08 Rhone Poulenc Rorer Sa Derivados de taxano,procedimiento para su preparacion y composicion farmaceutica que los contiene
US6794523B2 (en) * 1991-09-23 2004-09-21 Florida State University Taxanes having t-butoxycarbonyl substituted side-chains and pharmaceutical compositions containing them
WO1993021173A1 (en) * 1992-04-17 1993-10-28 Abbott Laboratories Taxol derivatives
FR2697019B1 (fr) 1992-10-15 1994-11-25 Rhone Poulenc Rorer Sa Nouveaux dérivés du taxane, leur préparation et les compositions pharmaceutiques qui les contiennent.
CA2147984C (en) 1992-11-13 2006-03-14 Robert A. Holton Butenyl-substituted taxanes and composition
EP0688212B1 (en) * 1993-03-05 2002-06-12 Florida State University C9 taxane derivatives and pharmaceutical compositions containing them
DE69432140T2 (de) * 1993-03-05 2003-07-31 Florida State University, Tallahassee Verfahren zur Herstellung von 9-Desoxotaxanen
US6710191B2 (en) * 1993-03-05 2004-03-23 Florida State University 9β-hydroxytetracyclic taxanes
DK1227093T3 (da) 1993-03-22 2005-08-29 Univ Florida State Beta-lactamer, der kan anvendes til fremstilling af taxaner med en furyl- eller thienylsubstitueret sidekæde
FR2707293A1 (fr) * 1993-07-08 1995-01-13 Rhone Poulenc Rorer Sa Nouveaux taxoides, leur préparation et les compositions pharmaceutiques qui les contiennent.
FR2715846A1 (fr) * 1994-02-07 1995-08-11 Rhone Poulenc Rorer Sa Nouvelle composition pharmceutique à base de taxoïdes.
IT1275936B1 (it) 1995-03-17 1997-10-24 Indena Spa Derivati della 10-deacetilbaccatina iii e della 10-deacetil-14b- idrossibaccatina iii loro metodo di preparazione e formulazioni
US5635531A (en) * 1996-07-08 1997-06-03 Bristol-Myers Squibb Company 3'-aminocarbonyloxy paclitaxels
US5739359A (en) 1997-01-24 1998-04-14 Virginia Tech Intellectual Properties, Inc. Methods for preparing 1-deoxy paclitaxels
US6048990A (en) * 1998-05-01 2000-04-11 Napro Biotherapeutics, Inc. Method for selective acylation of C-2'-O-protected-10-hydroxy-taxol at the C-10 position
AU776767B2 (en) * 2000-02-02 2004-09-23 Florida State University Research Foundation, Inc. C10 heterosubstituted acetate taxanes as antitumor agents
CO5280224A1 (es) * 2000-02-02 2003-05-30 Univ Florida State Res Found Taxanos sustituidos con ester en c7, utiles como agentes antitumorales y composiciones farmaceuticas que los contienen
WO2002076448A1 (en) 2001-03-23 2002-10-03 Napro Biotherapeutics, Inc. Molecular conjugates for use in treatment of cancer
CA2354471A1 (en) * 2001-07-31 2003-01-31 Florida State University Research Foundation, Inc. C10 ester substituted taxanes
EP1465618A2 (en) 2001-12-20 2004-10-13 Bristol-Myers Squibb Company Pharmaceutical compositions of orally active taxane derivatives having enhanced bioavailability
US6898834B1 (en) * 2003-03-03 2005-05-31 Westbridge Pty Ltd Barrel stave reclaim
AU2004275881A1 (en) 2003-09-25 2005-04-07 Tapestry Pharmaceuticals, Inc. 9,10-alpha,alpha-OH-taxane analogs and methods for production thereof
SI1664033T1 (sl) 2003-09-25 2008-04-30 Tapestry Pharmaceuticals Inc Analogi 9,10-alfa,alfa-oh-taksana in postopki za proizvodnjo le-teh
CA2616906A1 (en) 2005-05-12 2006-11-23 Tapestry Pharmaceuticals, Inc. Molecular constructs suitable for targeted conjugates
US20090156828A1 (en) 2005-12-21 2009-06-18 Tapestry Pharmaceuticals, Inc. Novel Compounds and Methods for Forming Taxanes and Using the Same
CA2634746A1 (en) 2005-12-21 2007-07-05 Tapestry Pharmaceuticals, Inc. Processes for taxane derivatives and intermediates useful therein
US20090306400A1 (en) 2006-03-27 2009-12-10 Henri John T Convergent process for the synthesis of taxane derivatives.
WO2008121476A1 (en) 2007-03-28 2008-10-09 Tapestry Pharmaceuticals, Inc. Biologically active taxane analogs and methods of treatment by oral administration
US20080207743A1 (en) 2007-02-28 2008-08-28 Rodger Lamb Biologically Active Taxane Analogs and Methods of Treatment
WO2008109360A1 (en) 2007-02-28 2008-09-12 Tapestry Pharmaceuticals, Inc Taxane analogs for the treatment of brain cancer

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