JP2007505854A5 - - Google Patents
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- Publication number
- JP2007505854A5 JP2007505854A5 JP2006526578A JP2006526578A JP2007505854A5 JP 2007505854 A5 JP2007505854 A5 JP 2007505854A5 JP 2006526578 A JP2006526578 A JP 2006526578A JP 2006526578 A JP2006526578 A JP 2006526578A JP 2007505854 A5 JP2007505854 A5 JP 2007505854A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- functional food
- ligand
- pparγ
- ligustilide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 claims 10
- 108010016731 PPAR gamma Proteins 0.000 claims 7
- YASAKCUCGLMORW-UHFFFAOYSA-N Rosiglitazone Chemical compound C=1C=CC=NC=1N(C)CCOC(C=C1)=CC=C1CC1SC(=O)NC1=O YASAKCUCGLMORW-UHFFFAOYSA-N 0.000 claims 6
- 239000003446 ligand Substances 0.000 claims 6
- HYAFETHFCAUJAY-UHFFFAOYSA-N pioglitazone Chemical compound N1=CC(CC)=CC=C1CCOC(C=C1)=CC=C1CC1C(=O)NC(=O)S1 HYAFETHFCAUJAY-UHFFFAOYSA-N 0.000 claims 6
- 235000013376 functional food Nutrition 0.000 claims 5
- WMBWREPUVVBILR-UHFFFAOYSA-N GCG Natural products C=1C(O)=C(O)C(O)=CC=1C1OC2=CC(O)=CC(O)=C2CC1OC(=O)C1=CC(O)=C(O)C(O)=C1 WMBWREPUVVBILR-UHFFFAOYSA-N 0.000 claims 4
- 102000000536 PPAR gamma Human genes 0.000 claims 4
- IQVQXVFMNOFTMU-FLIBITNWSA-N (Z)-ligustilide Chemical compound C1CC=CC2=C1C(=C/CCC)/OC2=O IQVQXVFMNOFTMU-FLIBITNWSA-N 0.000 claims 3
- 102000012132 Peroxisome proliferator-activated receptor gamma Human genes 0.000 claims 3
- IQVQXVFMNOFTMU-DHZHZOJOSA-N Z-ligustilide Natural products C1CC=CC2=C1C(=C/CCC)\OC2=O IQVQXVFMNOFTMU-DHZHZOJOSA-N 0.000 claims 3
- 229960005095 pioglitazone Drugs 0.000 claims 3
- 229960004586 rosiglitazone Drugs 0.000 claims 3
- 229930014124 (-)-epigallocatechin gallate Natural products 0.000 claims 2
- 235000004911 (-)-epigallocatechin gallate Nutrition 0.000 claims 2
- 208000008589 Obesity Diseases 0.000 claims 2
- 235000013361 beverage Nutrition 0.000 claims 2
- 206010012601 diabetes mellitus Diseases 0.000 claims 2
- VFSWRBJYBQXUTE-UHFFFAOYSA-N epi-Gallocatechin 3-O-gallate Natural products Oc1ccc2C(=O)C(OC(=O)c3cc(O)c(O)c(O)c3)C(Oc2c1)c4cc(O)c(O)c(O)c4 VFSWRBJYBQXUTE-UHFFFAOYSA-N 0.000 claims 2
- 235000013305 food Nutrition 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 235000020824 obesity Nutrition 0.000 claims 2
- 208000011580 syndromic disease Diseases 0.000 claims 2
- WMBWREPUVVBILR-GHTZIAJQSA-N (+)-gallocatechin gallate Chemical compound O([C@H]1CC2=C(O)C=C(C=C2O[C@@H]1C=1C=C(O)C(O)=C(O)C=1)O)C(=O)C1=CC(O)=C(O)C(O)=C1 WMBWREPUVVBILR-GHTZIAJQSA-N 0.000 claims 1
- WMBWREPUVVBILR-WIYYLYMNSA-N (-)-Epigallocatechin-3-o-gallate Chemical compound O([C@@H]1CC2=C(O)C=C(C=C2O[C@@H]1C=1C=C(O)C(O)=C(O)C=1)O)C(=O)C1=CC(O)=C(O)C(O)=C1 WMBWREPUVVBILR-WIYYLYMNSA-N 0.000 claims 1
- 229940030275 epigallocatechin gallate Drugs 0.000 claims 1
- LVJJFMLUMNSUFN-UHFFFAOYSA-N gallocatechin gallate Natural products C1=C(O)C=C2OC(C=3C=C(O)C(O)=CC=3)C(O)CC2=C1OC(=O)C1=CC(O)=C(O)C(O)=C1 LVJJFMLUMNSUFN-UHFFFAOYSA-N 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 239000013589 supplement Substances 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03021447 | 2003-09-23 | ||
| PCT/EP2004/010283 WO2005027661A1 (en) | 2003-09-23 | 2004-09-15 | Compositions for the treatment and prevention of diabetes mellitus |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007505854A JP2007505854A (ja) | 2007-03-15 |
| JP2007505854A5 true JP2007505854A5 (https=) | 2011-06-23 |
Family
ID=34354421
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006526578A Pending JP2007505854A (ja) | 2003-09-23 | 2004-09-15 | 糖尿病の治療および予防用組成物 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US7691420B2 (https=) |
| EP (1) | EP1662906A1 (https=) |
| JP (1) | JP2007505854A (https=) |
| KR (1) | KR20060121887A (https=) |
| CN (1) | CN100518733C (https=) |
| WO (1) | WO2005027661A1 (https=) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1605336A (zh) | 2003-10-10 | 2005-04-13 | 中国医学科学院药物研究所 | 左旋丁基苯酞在制备预防和治疗脑梗塞的药物中的应用 |
| KR20080020617A (ko) * | 2005-06-07 | 2008-03-05 | 디에스엠 아이피 어셋츠 비.브이. | (-)-에피갈로카테킨 갈레이트의 신규 용도 |
| US20090202659A1 (en) * | 2005-06-10 | 2009-08-13 | Gimble Jeffrey M | Modulation of Peripheral Clocks in Adipose Tissue |
| EA200802090A1 (ru) * | 2006-03-31 | 2010-04-30 | ДСМ АйПи АССЕТС Б.В. | Новое применение соединений и комбинаций соединений для улучшения внешнего вида |
| CN101516386B (zh) * | 2006-07-14 | 2013-05-15 | 帝斯曼知识产权资产管理有限公司 | 包含玫瑰果和其它活性剂的用于治疗炎性病症的组合物 |
| US20100215782A1 (en) * | 2008-10-22 | 2010-08-26 | Metaproteomics, Llc | Novel mitochondrial uncoupling methods and compositions for enhancing adipocyte thermogenesis |
| WO2011000593A1 (en) * | 2009-06-30 | 2011-01-06 | Unilever Plc | Method for determining susceptibility of individuals to polyphenols |
| EP2332427A1 (en) * | 2009-12-07 | 2011-06-15 | Nestec S.A. | low caloric fat replacers |
| WO2011162320A1 (ja) * | 2010-06-23 | 2011-12-29 | 国立大学法人九州大学 | Egcgまたはメチル化egcgとpde阻害剤との組み合わせ |
| RU2451506C1 (ru) * | 2011-06-02 | 2012-05-27 | Сергей Юрьевич Лешков | Комбинация для лечения сахарного диабета и его осложнений |
| JP5877731B2 (ja) * | 2012-02-28 | 2016-03-08 | 丸善製薬株式会社 | Ｕｃｐ−３発現促進剤 |
| JP6034107B2 (ja) * | 2012-09-25 | 2016-11-30 | 日本メナード化粧品株式会社 | 幹細胞から褐色脂肪細胞への分化促進剤 |
| JP2015155383A (ja) * | 2014-02-19 | 2015-08-27 | 株式会社東洋新薬 | 受容体発現亢進剤 |
| CN107446882B (zh) * | 2016-05-20 | 2021-06-22 | 东华大学 | 亚丁基苯酞的应用 |
| WO2021263072A1 (en) * | 2020-06-25 | 2021-12-30 | Dana-Farber Cancer Institute, Inc. | Methods of treating disease |
| CN119656183A (zh) * | 2024-09-30 | 2025-03-21 | 唐宁医药科技(济南)有限公司 | 一种归知糖疽有效成分配方在治疗糖尿病引起的周围神经病变中的应用 |
Family Cites Families (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4753935A (en) * | 1987-01-30 | 1988-06-28 | Syntex (U.S.A.) Inc. | Morpholinoethylesters of mycophenolic acid and pharmaceutical compositions |
| JPH01207233A (ja) | 1988-02-12 | 1989-08-21 | Tsumura & Co | 抗動脈硬化症剤 |
| JPH02243622A (ja) | 1989-03-16 | 1990-09-27 | Nippon Oil & Fats Co Ltd | 血中コレステロール低下用油脂組成物 |
| US5318986A (en) * | 1989-10-19 | 1994-06-07 | Mitsui Norin Co., Ltd. | Method of inhibiting the activity of α-amylase |
| JPH03228664A (ja) * | 1990-02-02 | 1991-10-09 | Meiji Seika Kaisha Ltd | 脂質の消化吸収抑制機能を有する食品 |
| JP3088787B2 (ja) * | 1991-07-08 | 2000-09-18 | 三井農林株式会社 | シュクラーゼ活性阻害剤 |
| JPH05292886A (ja) | 1992-04-21 | 1993-11-09 | Fuji Oil Co Ltd | 被マイグレーション防止能を有する油脂及びそれを含有 した食品並びに油脂含有食品のマイグレーション防止法 |
| JPH05292885A (ja) * | 1992-04-22 | 1993-11-09 | Asahi Denka Kogyo Kk | チョコレート組成物 |
| IN178310B (https=) | 1993-06-25 | 1997-03-22 | Mobius Consultancy Pty Ltd | |
| US5536499A (en) * | 1995-02-24 | 1996-07-16 | Chesebrough-Pond's Usa Co., Division Of Conopco, Inc. | Cosmetic compositions for reducing or preventing signs of cellulite |
| CN1069036C (zh) * | 1995-07-21 | 2001-08-01 | 崔景岳 | 灵芝仙饮 |
| JPH1118722A (ja) * | 1997-07-03 | 1999-01-26 | Lotte Co Ltd | 記憶力および学習能力を増強させる効果を有する脳機能を活性化する飲食物 |
| JP3496483B2 (ja) * | 1997-11-04 | 2004-02-09 | 三菱化学フーズ株式会社 | 密封容器入り茶類飲料 |
| US6428818B1 (en) * | 1999-03-30 | 2002-08-06 | Purdue Research Foundation | Tea catechin formulations and processes for making same |
| US6410061B1 (en) * | 1999-03-30 | 2002-06-25 | Purdue Research Foundation | Tea catechins as cancer specific proliferation inhibitors |
| US6299925B1 (en) * | 1999-06-29 | 2001-10-09 | Xel Herbaceuticals, Inc. | Effervescent green tea extract formulation |
| CN1182127C (zh) | 2000-06-28 | 2004-12-29 | 中国医学科学院药物研究所 | 新的取代的2-苯并[c]呋喃酮化合物,其制备方法以及包含它们的药物组合物 |
| US6455078B1 (en) * | 2000-10-18 | 2002-09-24 | Tzu-Sheng Wu | Medicinal herbal composition for treating liver diseases and HIV |
| US7968139B2 (en) * | 2000-11-17 | 2011-06-28 | Kao Corporation | Packaged beverages |
| JP3756438B2 (ja) * | 2001-03-02 | 2006-03-15 | 花王株式会社 | 容器詰飲料 |
| AU2002235731A1 (en) * | 2001-03-07 | 2002-09-19 | Novo Nordisk A/S | Combined use of derivatives of glp-1 analogs and ppar ligands |
| ITVR20010031A1 (it) | 2001-03-12 | 2002-09-12 | Hisanori Suzuki | Uso di epigallocatechin-3-gallato o suoi derivati nella profilassi e nel trattamento delle malattie neurodegenerative. |
| WO2002080936A1 (en) * | 2001-04-04 | 2002-10-17 | Ortho Mcneil Pharmaceutical, Inc. | Combination therapy comprising glucose reabsorption inhibitors and ppar modulators |
| DE10131057A1 (de) | 2001-06-29 | 2003-01-23 | Shandong Luya Pharmaceutical C | Weiche, Angelikaöl enthaltende Gelkapsel und deren Herstellung |
| US6447814B1 (en) * | 2001-08-28 | 2002-09-10 | Yung Shin Pharma Ind. Co. Ltd. | Chinese herbal composition for improving blood circulation and the method of preparing the same |
| JP4324335B2 (ja) * | 2001-09-07 | 2009-09-02 | 花王株式会社 | カテキン含有飲料 |
| JP2003095942A (ja) * | 2001-09-21 | 2003-04-03 | Ito En Ltd | 脂肪細胞におけるグルコース取込阻害剤及びｇｌｕｔ４トランスロケーション抑制剤、筋肉細胞におけるグルコース取込活性化剤並びに脂肪軽減飲食物 |
| JP3403400B1 (ja) * | 2001-09-28 | 2003-05-06 | 花王株式会社 | 容器詰飲料 |
| US6855346B2 (en) * | 2001-10-05 | 2005-02-15 | Tzu-Sheng Wu | Pharmaceutical composition having prophylactic effects on lamivudine-related disease relapse and drug resistance and methods of using the same |
| JP3643081B2 (ja) * | 2002-02-13 | 2005-04-27 | 株式会社京都栄養化学研究所 | 健康食品の製造方法 |
| US20030165580A1 (en) * | 2002-03-04 | 2003-09-04 | Xinxian Zhao | Safe pharmaceutical composition for treatment and prevention of gynecological disease |
| US20050256178A1 (en) * | 2002-08-23 | 2005-11-17 | Eggersdorfer Manfred L | Novel nutraceutical compositions comprising boitin |
| KR100504408B1 (ko) | 2002-10-29 | 2005-07-27 | 주식회사 코리아나화장품 | 생큐노라이드 ａ를 포함하는 피부 미백용 화장료 조성물 |
| JP2006508096A (ja) | 2002-11-07 | 2006-03-09 | ディーエスエム アイピー アセッツ ビー．ブイ． | 没食子酸エピガロカテキンを含む新規な栄養補助組成物 |
-
2004
- 2004-09-15 EP EP04765197A patent/EP1662906A1/en not_active Withdrawn
- 2004-09-15 KR KR1020067005689A patent/KR20060121887A/ko not_active Ceased
- 2004-09-15 CN CNB2004800275244A patent/CN100518733C/zh not_active Expired - Fee Related
- 2004-09-15 US US10/573,222 patent/US7691420B2/en not_active Expired - Fee Related
- 2004-09-15 JP JP2006526578A patent/JP2007505854A/ja active Pending
- 2004-09-15 WO PCT/EP2004/010283 patent/WO2005027661A1/en not_active Ceased
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