JP2007504132A5 - - Google Patents

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Publication number
JP2007504132A5
JP2007504132A5 JP2006524705A JP2006524705A JP2007504132A5 JP 2007504132 A5 JP2007504132 A5 JP 2007504132A5 JP 2006524705 A JP2006524705 A JP 2006524705A JP 2006524705 A JP2006524705 A JP 2006524705A JP 2007504132 A5 JP2007504132 A5 JP 2007504132A5
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JP
Japan
Prior art keywords
compound
daltons
molecular weight
group
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2006524705A
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English (en)
Japanese (ja)
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JP2007504132A (ja
JP4848277B2 (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2004/026422 external-priority patent/WO2005023834A2/en
Publication of JP2007504132A publication Critical patent/JP2007504132A/ja
Publication of JP2007504132A5 publication Critical patent/JP2007504132A5/ja
Application granted granted Critical
Publication of JP4848277B2 publication Critical patent/JP4848277B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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JP2006524705A 2003-08-28 2004-08-13 受容体に結合するペプチドおよび化合物 Expired - Lifetime JP4848277B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US49874003P 2003-08-28 2003-08-28
US60/498,740 2003-08-28
PCT/US2004/026422 WO2005023834A2 (en) 2003-08-28 2004-08-13 Peptides and compounds that bind to thrombopoietin receptors

Publications (3)

Publication Number Publication Date
JP2007504132A JP2007504132A (ja) 2007-03-01
JP2007504132A5 true JP2007504132A5 (cg-RX-API-DMAC10.html) 2007-09-20
JP4848277B2 JP4848277B2 (ja) 2011-12-28

Family

ID=34272720

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006524705A Expired - Lifetime JP4848277B2 (ja) 2003-08-28 2004-08-13 受容体に結合するペプチドおよび化合物

Country Status (32)

Country Link
US (1) US7576056B2 (cg-RX-API-DMAC10.html)
EP (1) EP1675606B1 (cg-RX-API-DMAC10.html)
JP (1) JP4848277B2 (cg-RX-API-DMAC10.html)
KR (2) KR20120078742A (cg-RX-API-DMAC10.html)
CN (2) CN1871022B (cg-RX-API-DMAC10.html)
AR (1) AR045530A1 (cg-RX-API-DMAC10.html)
AU (1) AU2004270656B2 (cg-RX-API-DMAC10.html)
BR (1) BRPI0414008B8 (cg-RX-API-DMAC10.html)
CA (1) CA2537421C (cg-RX-API-DMAC10.html)
CY (1) CY1118965T1 (cg-RX-API-DMAC10.html)
DK (1) DK1675606T3 (cg-RX-API-DMAC10.html)
EA (1) EA009286B1 (cg-RX-API-DMAC10.html)
EC (1) ECSP066396A (cg-RX-API-DMAC10.html)
ES (1) ES2626107T3 (cg-RX-API-DMAC10.html)
HR (1) HRP20170810T1 (cg-RX-API-DMAC10.html)
HU (1) HUE032370T2 (cg-RX-API-DMAC10.html)
IL (1) IL173965A (cg-RX-API-DMAC10.html)
IS (1) IS8300A (cg-RX-API-DMAC10.html)
LT (1) LT1675606T (cg-RX-API-DMAC10.html)
ME (1) ME00313B (cg-RX-API-DMAC10.html)
MX (1) MXPA06002292A (cg-RX-API-DMAC10.html)
NO (1) NO344233B1 (cg-RX-API-DMAC10.html)
NZ (1) NZ545455A (cg-RX-API-DMAC10.html)
PL (1) PL1675606T3 (cg-RX-API-DMAC10.html)
PT (1) PT1675606T (cg-RX-API-DMAC10.html)
RS (2) RS20060141A (cg-RX-API-DMAC10.html)
SG (1) SG131110A1 (cg-RX-API-DMAC10.html)
SI (1) SI1675606T1 (cg-RX-API-DMAC10.html)
TW (1) TWI348375B (cg-RX-API-DMAC10.html)
UA (1) UA82710C2 (cg-RX-API-DMAC10.html)
WO (1) WO2005023834A2 (cg-RX-API-DMAC10.html)
ZA (1) ZA200602495B (cg-RX-API-DMAC10.html)

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US7091311B2 (en) * 1996-06-07 2006-08-15 Smithkline Beecham Corporation Peptides and compounds that bind to a receptor
ATE348163T1 (de) 1998-10-23 2007-01-15 Amgen Inc Thrombopoietin substitute
DK1542714T3 (da) * 2002-09-18 2014-05-26 Janssen Pharmaceuticals Inc Fremgangsmåder til forøgelse af produktion af blodplader og hæmatopoietiske stamceller
US20040149235A1 (en) * 2002-10-04 2004-08-05 Pogue Albert S. Apparatus and method for removal of waste from animal production facilities
US7723295B2 (en) * 2003-08-28 2010-05-25 Ortho-Mcneil Pharmaceutical, Inc. Peptides and compounds that bind to a receptor
RS20060141A (sr) 2003-08-28 2008-08-07 Ortho-Mcneil Pharmaceutical Inc., Peptidi i jedinjenja koja se vežu za receptor
US7615533B2 (en) 2004-08-16 2009-11-10 Janssen Pharmaceutica N.V. TPO peptide compounds for treatment of anemia
EP1986677A2 (en) * 2006-01-25 2008-11-05 Amgen Inc. Thrombopoietic compounds
AR059573A1 (es) * 2006-02-14 2008-04-16 Janssen Pharmaceutica Nv Uso de compuestos peptidicos de tpo y composiciones farmaceuticas en el tratamiento de la anemia
PT1984014E (pt) * 2006-02-14 2014-11-13 Janssen Pharmaceutica Nv Utilização de compostos de péptidos tpo e composições farmacêuticas no tratamento da anemia
US7981425B2 (en) 2006-06-19 2011-07-19 Amgen Inc. Thrombopoietic compounds
KR20110015448A (ko) * 2008-06-03 2011-02-15 얀센 파마슈티카 엔.브이. 암 치료와 관련된 혈액 질환을 예방하기 위한 tpo 모방 펩티드
CN103635514B (zh) 2011-06-23 2016-01-20 株式会社岛津制作所 支链型两亲性嵌段聚合物、使用其的分子聚集体及药物输送系统
JP7481252B2 (ja) * 2017-07-26 2024-05-10 ヤンセン ファーマシューティカ エヌ.ベー. 標的放射線治療誘発性血管完全性を保護する方法
US20200237872A1 (en) 2019-01-25 2020-07-30 Janssen Pharmaceutica Nv Methods of enhancing protection against organ and vascular injury, hematopoietic recovery and survival in response to total body radiation/chemical exposure
US11273203B2 (en) 2019-01-25 2022-03-15 Janssen Pharmaceutica Nv Methods of mitigating toxic effects of vesicants and caustic gas
MA54820A (fr) 2019-01-25 2021-12-01 Janssen Pharmaceutica Nv Méthodes d'atténuation d'une lésion hépatique et de promotion d'une hypertrophie hépatique, de régénération du foie et de prise de greffe de cellules hépatiques conjointement avec des traitements par radiothérapie et/ou radiomimétiques
CN118660955A (zh) 2021-10-01 2024-09-17 詹森药业有限公司 增加祖细胞生产的方法
WO2024095178A1 (en) 2022-11-01 2024-05-10 Janssen Pharmaceutica Nv Thrombopoietin mimetic for use in the treatment of acute liver failure

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US5143854A (en) 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
US5326558A (en) * 1989-08-08 1994-07-05 Genetics Institute, Inc. Megakaryocytopoietic factor
IL96477A0 (en) 1989-12-01 1991-08-16 Amgen Inc Megakaryocyte production
DK167813B1 (da) * 1989-12-07 1993-12-20 Carlbiotech Ltd As Pentapeptidderivat, farmaceutisk acceptable salte heraf, fremgangsmaade til fremstilling deraf og farmaceutisk praeparat indeholdende et saadant derivat
US5571508A (en) 1989-12-18 1996-11-05 Amrad Corporation Limited Method for the treatment of thrombocytopenia and pharmaceutical compositions useful therefor
IT1241395B (it) 1990-04-02 1994-01-10 Eniricerche Spa Composti immunogenici,il procedimento per la loro sintesi e loro impiego per la preparazione di vaccini antimalaria
US5141851A (en) * 1990-04-18 1992-08-25 Board Of Regents, The University Of Texas System Isolated farnesyl protein transferase enzyme
US5250732A (en) * 1991-07-18 1993-10-05 Genentech, Inc. Ketamine analogues for treatment of thrombocytopenia
US5270170A (en) * 1991-10-16 1993-12-14 Affymax Technologies N.V. Peptide library and screening method
AU680422B2 (en) 1992-06-11 1997-07-31 Alkermes Controlled Therapeutics, Inc. Erythropoietin drug delivery system
EP0945504A3 (en) * 1992-12-11 1999-12-08 The University Of Florida Materials and method for control of pests
WO1995011922A1 (en) 1993-10-29 1995-05-04 Affymax Technologies N.V. In vitro peptide and antibody display libraries
GB2285446B (en) 1994-01-03 1999-07-28 Genentech Inc Thrombopoietin
WO1995021920A1 (en) 1994-02-14 1995-08-17 Zymogenetics, Inc. Hematopoietic protein and materials and methods for making it
EP0723456A1 (en) 1994-02-14 1996-07-31 The University Of Washington Methods for stimulating erythropoiesis using thrombopoietin
EP0668352A1 (en) 1994-02-14 1995-08-23 Kirin Brewery Company, Ltd. Protein having TPO activity
WO1995021919A2 (en) 1994-02-14 1995-08-17 Kirin Brewery Company, Limited Protein having tpo activity
EE9600121A (et) 1994-03-31 1997-04-15 Amgen Inc. Megakarüotsüütide kasvu ja diferentseerumist stimuleerivad kompositsioonid ja meetodid
US5571686A (en) 1994-04-14 1996-11-05 Massachusetts Institute Of Technology Method of using megapoietin for prolonging the survival & viability of platlets
CA2180021A1 (en) * 1994-11-04 1996-05-17 Yoichi Kawashima Novel 1,3-dialkylurea derivatives having a hydroxyl group
US5641655A (en) 1994-11-30 1997-06-24 Zymogenetics, Inc. Methods for producing thrombopoietin polypeptides using a mammalian tissue plasminogen activator secretory peptide
WO1996017062A1 (en) 1994-11-30 1996-06-06 Zymogenetics, Inc. Low molecular weight thrombopoietin
WO1996034016A1 (en) 1995-04-26 1996-10-31 Kyowa Hakko Kogyo Co., Ltd. Novel polypeptides
CN1966520B (zh) * 1995-06-07 2012-07-11 葛兰素集团有限公司 结合血小板生成素受体的肽和化合物
US6251864B1 (en) * 1995-06-07 2001-06-26 Glaxo Group Limited Peptides and compounds that bind to a receptor
US5869451A (en) 1995-06-07 1999-02-09 Glaxo Group Limited Peptides and compounds that bind to a receptor
US6060052A (en) * 1995-10-30 2000-05-09 Systemix, Inc. Methods for use of Mpl ligands with primitive human hematopoietic stem cells
US5932546A (en) * 1996-10-04 1999-08-03 Glaxo Wellcome Inc. Peptides and compounds that bind to the thrombopoietin receptor
AU771460B2 (en) 1999-09-24 2004-03-25 Smithkline Beecham Corporation Thrombopoietin mimetics
ES2266104T3 (es) * 2000-12-22 2007-03-01 Ipsen Manufacturing Ireland Limited Procedimiento para la sintesis de un peptido lhrh.
AU2002307062A1 (en) 2001-04-02 2002-10-15 Purdue Pharma L.P. Thrombopoietin (tpo) synthebody for stimulation of platelet production
DK1542714T3 (da) * 2002-09-18 2014-05-26 Janssen Pharmaceuticals Inc Fremgangsmåder til forøgelse af produktion af blodplader og hæmatopoietiske stamceller
RS20060141A (sr) 2003-08-28 2008-08-07 Ortho-Mcneil Pharmaceutical Inc., Peptidi i jedinjenja koja se vežu za receptor

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