NO344233B1 - Peptider og forbindelser som binder til thrombopoietin-reseptorer - Google Patents
Peptider og forbindelser som binder til thrombopoietin-reseptorer Download PDFInfo
- Publication number
- NO344233B1 NO344233B1 NO20061346A NO20061346A NO344233B1 NO 344233 B1 NO344233 B1 NO 344233B1 NO 20061346 A NO20061346 A NO 20061346A NO 20061346 A NO20061346 A NO 20061346A NO 344233 B1 NO344233 B1 NO 344233B1
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- compound
- peptide
- cells
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Classifications
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/524—Thrombopoietin, i.e. C-MPL ligand
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- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Toxicology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Polyethers (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US49874003P | 2003-08-28 | 2003-08-28 | |
| PCT/US2004/026422 WO2005023834A2 (en) | 2003-08-28 | 2004-08-13 | Peptides and compounds that bind to thrombopoietin receptors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20061346L NO20061346L (no) | 2006-05-22 |
| NO344233B1 true NO344233B1 (no) | 2019-10-14 |
Family
ID=34272720
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20061346A NO344233B1 (no) | 2003-08-28 | 2006-03-24 | Peptider og forbindelser som binder til thrombopoietin-reseptorer |
Country Status (32)
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7091311B2 (en) * | 1996-06-07 | 2006-08-15 | Smithkline Beecham Corporation | Peptides and compounds that bind to a receptor |
| ATE348163T1 (de) | 1998-10-23 | 2007-01-15 | Amgen Inc | Thrombopoietin substitute |
| DK1542714T3 (da) * | 2002-09-18 | 2014-05-26 | Janssen Pharmaceuticals Inc | Fremgangsmåder til forøgelse af produktion af blodplader og hæmatopoietiske stamceller |
| US20040149235A1 (en) * | 2002-10-04 | 2004-08-05 | Pogue Albert S. | Apparatus and method for removal of waste from animal production facilities |
| US7723295B2 (en) * | 2003-08-28 | 2010-05-25 | Ortho-Mcneil Pharmaceutical, Inc. | Peptides and compounds that bind to a receptor |
| RS20060141A (sr) | 2003-08-28 | 2008-08-07 | Ortho-Mcneil Pharmaceutical Inc., | Peptidi i jedinjenja koja se vežu za receptor |
| US7615533B2 (en) | 2004-08-16 | 2009-11-10 | Janssen Pharmaceutica N.V. | TPO peptide compounds for treatment of anemia |
| EP1986677A2 (en) * | 2006-01-25 | 2008-11-05 | Amgen Inc. | Thrombopoietic compounds |
| AR059573A1 (es) * | 2006-02-14 | 2008-04-16 | Janssen Pharmaceutica Nv | Uso de compuestos peptidicos de tpo y composiciones farmaceuticas en el tratamiento de la anemia |
| PT1984014E (pt) * | 2006-02-14 | 2014-11-13 | Janssen Pharmaceutica Nv | Utilização de compostos de péptidos tpo e composições farmacêuticas no tratamento da anemia |
| US7981425B2 (en) | 2006-06-19 | 2011-07-19 | Amgen Inc. | Thrombopoietic compounds |
| KR20110015448A (ko) * | 2008-06-03 | 2011-02-15 | 얀센 파마슈티카 엔.브이. | 암 치료와 관련된 혈액 질환을 예방하기 위한 ｔｐｏ 모방 펩티드 |
| CN103635514B (zh) | 2011-06-23 | 2016-01-20 | 株式会社岛津制作所 | 支链型两亲性嵌段聚合物、使用其的分子聚集体及药物输送系统 |
| JP7481252B2 (ja) * | 2017-07-26 | 2024-05-10 | ヤンセン ファーマシューティカ エヌ．ベー． | 標的放射線治療誘発性血管完全性を保護する方法 |
| US20200237872A1 (en) | 2019-01-25 | 2020-07-30 | Janssen Pharmaceutica Nv | Methods of enhancing protection against organ and vascular injury, hematopoietic recovery and survival in response to total body radiation/chemical exposure |
| US11273203B2 (en) | 2019-01-25 | 2022-03-15 | Janssen Pharmaceutica Nv | Methods of mitigating toxic effects of vesicants and caustic gas |
| MA54820A (fr) | 2019-01-25 | 2021-12-01 | Janssen Pharmaceutica Nv | Méthodes d'atténuation d'une lésion hépatique et de promotion d'une hypertrophie hépatique, de régénération du foie et de prise de greffe de cellules hépatiques conjointement avec des traitements par radiothérapie et/ou radiomimétiques |
| CN118660955A (zh) | 2021-10-01 | 2024-09-17 | 詹森药业有限公司 | 增加祖细胞生产的方法 |
| WO2024095178A1 (en) | 2022-11-01 | 2024-05-10 | Janssen Pharmaceutica Nv | Thrombopoietin mimetic for use in the treatment of acute liver failure |
Citations (1)
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|---|---|---|---|---|
| WO1996040750A1 (en) * | 1995-06-07 | 1996-12-19 | Glaxo Group Limited | Peptides and compounds that bind to a thrombopoietin receptor |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US5143854A (en) | 1989-06-07 | 1992-09-01 | Affymax Technologies N.V. | Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof |
| US5326558A (en) * | 1989-08-08 | 1994-07-05 | Genetics Institute, Inc. | Megakaryocytopoietic factor |
| IL96477A0 (en) | 1989-12-01 | 1991-08-16 | Amgen Inc | Megakaryocyte production |
| DK167813B1 (da) * | 1989-12-07 | 1993-12-20 | Carlbiotech Ltd As | Pentapeptidderivat, farmaceutisk acceptable salte heraf, fremgangsmaade til fremstilling deraf og farmaceutisk praeparat indeholdende et saadant derivat |
| US5571508A (en) | 1989-12-18 | 1996-11-05 | Amrad Corporation Limited | Method for the treatment of thrombocytopenia and pharmaceutical compositions useful therefor |
| IT1241395B (it) | 1990-04-02 | 1994-01-10 | Eniricerche Spa | Composti immunogenici,il procedimento per la loro sintesi e loro impiego per la preparazione di vaccini antimalaria |
| US5141851A (en) * | 1990-04-18 | 1992-08-25 | Board Of Regents, The University Of Texas System | Isolated farnesyl protein transferase enzyme |
| US5250732A (en) * | 1991-07-18 | 1993-10-05 | Genentech, Inc. | Ketamine analogues for treatment of thrombocytopenia |
| US5270170A (en) * | 1991-10-16 | 1993-12-14 | Affymax Technologies N.V. | Peptide library and screening method |
| AU680422B2 (en) | 1992-06-11 | 1997-07-31 | Alkermes Controlled Therapeutics, Inc. | Erythropoietin drug delivery system |
| EP0945504A3 (en) * | 1992-12-11 | 1999-12-08 | The University Of Florida | Materials and method for control of pests |
| WO1995011922A1 (en) | 1993-10-29 | 1995-05-04 | Affymax Technologies N.V. | In vitro peptide and antibody display libraries |
| GB2285446B (en) | 1994-01-03 | 1999-07-28 | Genentech Inc | Thrombopoietin |
| WO1995021920A1 (en) | 1994-02-14 | 1995-08-17 | Zymogenetics, Inc. | Hematopoietic protein and materials and methods for making it |
| EP0723456A1 (en) | 1994-02-14 | 1996-07-31 | The University Of Washington | Methods for stimulating erythropoiesis using thrombopoietin |
| EP0668352A1 (en) | 1994-02-14 | 1995-08-23 | Kirin Brewery Company, Ltd. | Protein having TPO activity |
| WO1995021919A2 (en) | 1994-02-14 | 1995-08-17 | Kirin Brewery Company, Limited | Protein having tpo activity |
| EE9600121A (et) | 1994-03-31 | 1997-04-15 | Amgen Inc. | Megakarüotsüütide kasvu ja diferentseerumist stimuleerivad kompositsioonid ja meetodid |
| US5571686A (en) | 1994-04-14 | 1996-11-05 | Massachusetts Institute Of Technology | Method of using megapoietin for prolonging the survival & viability of platlets |
| CA2180021A1 (en) * | 1994-11-04 | 1996-05-17 | Yoichi Kawashima | Novel 1,3-dialkylurea derivatives having a hydroxyl group |
| US5641655A (en) | 1994-11-30 | 1997-06-24 | Zymogenetics, Inc. | Methods for producing thrombopoietin polypeptides using a mammalian tissue plasminogen activator secretory peptide |
| WO1996017062A1 (en) | 1994-11-30 | 1996-06-06 | Zymogenetics, Inc. | Low molecular weight thrombopoietin |
| WO1996034016A1 (en) | 1995-04-26 | 1996-10-31 | Kyowa Hakko Kogyo Co., Ltd. | Novel polypeptides |
| US6251864B1 (en) * | 1995-06-07 | 2001-06-26 | Glaxo Group Limited | Peptides and compounds that bind to a receptor |
| US5869451A (en) | 1995-06-07 | 1999-02-09 | Glaxo Group Limited | Peptides and compounds that bind to a receptor |
| US6060052A (en) * | 1995-10-30 | 2000-05-09 | Systemix, Inc. | Methods for use of Mpl ligands with primitive human hematopoietic stem cells |
| US5932546A (en) * | 1996-10-04 | 1999-08-03 | Glaxo Wellcome Inc. | Peptides and compounds that bind to the thrombopoietin receptor |
| AU771460B2 (en) | 1999-09-24 | 2004-03-25 | Smithkline Beecham Corporation | Thrombopoietin mimetics |
| ES2266104T3 (es) * | 2000-12-22 | 2007-03-01 | Ipsen Manufacturing Ireland Limited | Procedimiento para la sintesis de un peptido lhrh. |
| AU2002307062A1 (en) | 2001-04-02 | 2002-10-15 | Purdue Pharma L.P. | Thrombopoietin (tpo) synthebody for stimulation of platelet production |
| DK1542714T3 (da) * | 2002-09-18 | 2014-05-26 | Janssen Pharmaceuticals Inc | Fremgangsmåder til forøgelse af produktion af blodplader og hæmatopoietiske stamceller |
| RS20060141A (sr) | 2003-08-28 | 2008-08-07 | Ortho-Mcneil Pharmaceutical Inc., | Peptidi i jedinjenja koja se vežu za receptor |
-
2004
- 2004-08-13 RS YUP-2006/0141A patent/RS20060141A/sr unknown
- 2004-08-13 AU AU2004270656A patent/AU2004270656B2/en not_active Expired
- 2004-08-13 HR HRP20170810TT patent/HRP20170810T1/hr unknown
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- 2004-08-13 ME MEP-2008-485A patent/ME00313B/me unknown
- 2004-08-13 RS YU20060141A patent/RS56387B1/sr unknown
- 2004-08-13 ES ES04781153.4T patent/ES2626107T3/es not_active Expired - Lifetime
- 2004-08-13 UA UAA200602523A patent/UA82710C2/uk unknown
- 2004-08-13 WO PCT/US2004/026422 patent/WO2005023834A2/en not_active Ceased
- 2004-08-13 CN CN2004800314520A patent/CN1871022B/zh not_active Expired - Lifetime
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- 2004-08-13 US US10/918,561 patent/US7576056B2/en not_active Expired - Lifetime
- 2004-08-13 KR KR1020127014067A patent/KR20120078742A/ko not_active Withdrawn
- 2004-08-13 MX MXPA06002292A patent/MXPA06002292A/es active IP Right Grant
- 2004-08-13 BR BRPI0414008A patent/BRPI0414008B8/pt not_active IP Right Cessation
- 2004-08-13 LT LTEP04781153.4T patent/LT1675606T/lt unknown
- 2004-08-13 KR KR1020067003755A patent/KR101183875B1/ko not_active Expired - Fee Related
- 2004-08-13 DK DK04781153.4T patent/DK1675606T3/en active
- 2004-08-13 CN CN201110134196.XA patent/CN102241742B/zh not_active Expired - Lifetime
- 2004-08-13 PL PL04781153T patent/PL1675606T3/pl unknown
- 2004-08-13 EA EA200600477A patent/EA009286B1/ru unknown
- 2004-08-13 SG SG200701488-9A patent/SG131110A1/en unknown
- 2004-08-13 SI SI200432391A patent/SI1675606T1/sl unknown
- 2004-08-27 TW TW093125674A patent/TWI348375B/zh not_active IP Right Cessation
- 2004-08-27 AR ARP040103101A patent/AR045530A1/es active IP Right Grant
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Patent Citations (1)
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|---|---|---|---|---|
| WO1996040750A1 (en) * | 1995-06-07 | 1996-12-19 | Glaxo Group Limited | Peptides and compounds that bind to a thrombopoietin receptor |
Non-Patent Citations (2)
| Title |
|---|
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| DE SERRES M ET AL: "Pharmacokinetics and hematological effects of the PEGylated thrombopoietin peptide mimetic GW395058 in rats and monkeys after intravenous or subcutaneous administration.", STEM CELLS (MIAMISBURG), vol. 17, no. 6, 1 January 1999 (1999-01-01), pages 316 - 326, XP002422606, ISSN: 1066-5099 * |
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