JP2007500244A5 - - Google Patents
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- Publication number
- JP2007500244A5 JP2007500244A5 JP2006533590A JP2006533590A JP2007500244A5 JP 2007500244 A5 JP2007500244 A5 JP 2007500244A5 JP 2006533590 A JP2006533590 A JP 2006533590A JP 2006533590 A JP2006533590 A JP 2006533590A JP 2007500244 A5 JP2007500244 A5 JP 2007500244A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- combination
- polymers
- hydroxypropyl methylcellulose
- carboxyvinyl polymer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 claims 13
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 claims 13
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 claims 13
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 claims 13
- 229920000642 polymer Polymers 0.000 claims 13
- 229920002125 Sokalan® Polymers 0.000 claims 8
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims 6
- 229920002674 hyaluronan Polymers 0.000 claims 6
- 229960003160 hyaluronic acid Drugs 0.000 claims 6
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims 4
- 229920000663 Hydroxyethyl cellulose Polymers 0.000 claims 3
- 239000004354 Hydroxyethyl cellulose Substances 0.000 claims 3
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 claims 3
- RFRMMZAKBNXNHE-UHFFFAOYSA-N 6-[4,6-dihydroxy-5-(2-hydroxyethoxy)-2-(hydroxymethyl)oxan-3-yl]oxy-2-(hydroxymethyl)-5-(2-hydroxypropoxy)oxane-3,4-diol Chemical compound CC(O)COC1C(O)C(O)C(CO)OC1OC1C(O)C(OCCO)C(O)OC1CO RFRMMZAKBNXNHE-UHFFFAOYSA-N 0.000 claims 2
- 229920002907 Guar gum Polymers 0.000 claims 2
- 239000003732 agents acting on the eye Substances 0.000 claims 2
- KGBXLFKZBHKPEV-UHFFFAOYSA-N boric acid Chemical compound OB(O)O KGBXLFKZBHKPEV-UHFFFAOYSA-N 0.000 claims 2
- 239000004327 boric acid Substances 0.000 claims 2
- 239000000665 guar gum Substances 0.000 claims 2
- 235000010417 guar gum Nutrition 0.000 claims 2
- 229960002154 guar gum Drugs 0.000 claims 2
- 229940023490 ophthalmic product Drugs 0.000 claims 2
- 239000011780 sodium chloride Substances 0.000 claims 2
- 230000002195 synergetic effect Effects 0.000 claims 2
- 238000011200 topical administration Methods 0.000 claims 2
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 claims 1
- RFIMISVNSAUMBU-UHFFFAOYSA-N 2-(hydroxymethyl)-2-(prop-2-enoxymethyl)propane-1,3-diol Chemical compound OCC(CO)(CO)COCC=C RFIMISVNSAUMBU-UHFFFAOYSA-N 0.000 claims 1
- NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims 1
- 208000003556 Dry Eye Syndromes Diseases 0.000 claims 1
- 206010013774 Dry eye Diseases 0.000 claims 1
- 229940086737 allyl sucrose Drugs 0.000 claims 1
- 239000004037 angiogenesis inhibitor Substances 0.000 claims 1
- 239000000043 antiallergic agent Substances 0.000 claims 1
- 239000000030 antiglaucoma agent Substances 0.000 claims 1
- 229960005475 antiinfective agent Drugs 0.000 claims 1
- 239000004599 antimicrobial Substances 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 239000003974 emollient agent Substances 0.000 claims 1
- 239000003623 enhancer Substances 0.000 claims 1
- 239000003102 growth factor Substances 0.000 claims 1
- -1 hydroxypropyl Chemical group 0.000 claims 1
- 239000000041 non-steroidal anti-inflammatory agent Substances 0.000 claims 1
- 229940021182 non-steroidal anti-inflammatory drug Drugs 0.000 claims 1
- 239000003002 pH adjusting agent Substances 0.000 claims 1
- 239000003755 preservative agent Substances 0.000 claims 1
- 230000002335 preservative effect Effects 0.000 claims 1
- 239000002904 solvent Substances 0.000 claims 1
- 239000003381 stabilizer Substances 0.000 claims 1
- 239000002294 steroidal antiinflammatory agent Substances 0.000 claims 1
- 239000004094 surface-active agent Substances 0.000 claims 1
- 208000024891 symptom Diseases 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US47825303P | 2003-06-13 | 2003-06-13 | |
| US60/478,253 | 2003-06-13 | ||
| PCT/US2004/018068 WO2004112836A2 (en) | 2003-06-13 | 2004-06-08 | Ophthalmic compositions containing a synergistic combination of two polymers |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010253316A Division JP2011026354A (ja) | 2003-06-13 | 2010-11-11 | ２種のポリマーの相乗作用的組み合わせを含む眼科用組成物 |
| JP2011138663A Division JP2011184463A (ja) | 2003-06-13 | 2011-06-22 | ２種のポリマーの相乗作用的組み合わせを含む眼科用組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2007500244A JP2007500244A (ja) | 2007-01-11 |
| JP2007500244A5 true JP2007500244A5 (enExample) | 2007-06-28 |
| JP4860475B2 JP4860475B2 (ja) | 2012-01-25 |
Family
ID=33539082
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006533590A Expired - Lifetime JP4860475B2 (ja) | 2003-06-13 | 2004-06-06 | ２種のポリマーの相乗作用的組み合わせを含む眼科用組成物 |
| JP2010253316A Pending JP2011026354A (ja) | 2003-06-13 | 2010-11-11 | ２種のポリマーの相乗作用的組み合わせを含む眼科用組成物 |
| JP2011138663A Pending JP2011184463A (ja) | 2003-06-13 | 2011-06-22 | ２種のポリマーの相乗作用的組み合わせを含む眼科用組成物 |
| JP2013032842A Pending JP2013100360A (ja) | 2003-06-13 | 2013-02-22 | ２種のポリマーの相乗作用的組み合わせを含む眼科用組成物 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010253316A Pending JP2011026354A (ja) | 2003-06-13 | 2010-11-11 | ２種のポリマーの相乗作用的組み合わせを含む眼科用組成物 |
| JP2011138663A Pending JP2011184463A (ja) | 2003-06-13 | 2011-06-22 | ２種のポリマーの相乗作用的組み合わせを含む眼科用組成物 |
| JP2013032842A Pending JP2013100360A (ja) | 2003-06-13 | 2013-02-22 | ２種のポリマーの相乗作用的組み合わせを含む眼科用組成物 |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US7709012B2 (enExample) |
| EP (5) | EP2116227B1 (enExample) |
| JP (4) | JP4860475B2 (enExample) |
| KR (5) | KR101147046B1 (enExample) |
| CN (1) | CN100475192C (enExample) |
| AU (2) | AU2004249137B2 (enExample) |
| BR (1) | BRPI0411361B1 (enExample) |
| CA (6) | CA2839928C (enExample) |
| DK (1) | DK2116227T3 (enExample) |
| ES (3) | ES2570856T3 (enExample) |
| MX (1) | MXPA05013290A (enExample) |
| PL (1) | PL2116227T3 (enExample) |
| PT (1) | PT2116227E (enExample) |
| SI (1) | SI2116227T1 (enExample) |
| WO (1) | WO2004112836A2 (enExample) |
| ZA (1) | ZA200509440B (enExample) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8580851B2 (en) | 2002-08-21 | 2013-11-12 | Sucampo Ag | Ophthalmic solution |
| TWI336257B (en) * | 2003-06-13 | 2011-01-21 | Alcon Inc | Ophthalmic compositions containing a synergistic combination of three polymers |
| US7947295B2 (en) * | 2003-06-13 | 2011-05-24 | Alcon, Inc. | Ophthalmic compositions containing a synergistic combination of two polymers |
| US7759296B2 (en) * | 2003-06-19 | 2010-07-20 | Lubrizol Advanced Materials, Inc. | Cationic polymers and fixative application therefor |
| EP1661573B1 (en) * | 2003-08-21 | 2013-09-25 | Sucampo AG | Ophtalmic composition comprising unoprostone ispopropyl ester and a viscosity agent |
| US20080050335A1 (en) * | 2006-07-25 | 2008-02-28 | Osmotica Corp. | Ophthalmic Solutions |
| US20080057022A1 (en) * | 2006-08-30 | 2008-03-06 | Erning Xia | Ophthalmic Pharmaceutical Compositions and Uses Thereof |
| US8138156B2 (en) * | 2006-10-18 | 2012-03-20 | Bausch & Lomb Incorporated | Ophthalmic compositions containing diglycine |
| CN101605531B (zh) * | 2007-02-09 | 2012-10-10 | 爱尔康公司 | 含有三种聚合物的协同组合的眼用组合物 |
| US8759321B2 (en) * | 2007-06-13 | 2014-06-24 | Bausch & Lomb Incorporated | Ophthalmic composition with hyaluronic acid and polymeric biguanide |
| US20100197811A1 (en) | 2007-06-26 | 2010-08-05 | Hidekazu Suzuki | Aqueous composition |
| WO2009028674A1 (ja) | 2007-08-29 | 2009-03-05 | Wakamoto Pharmaceutical Co., Ltd. | ラタノプロスト含有水性医薬組成物 |
| US9096819B2 (en) | 2008-01-31 | 2015-08-04 | Bausch & Lomb Incorporated | Ophthalmic compositions with an amphoteric surfactant and an anionic biopolymer |
| US8119112B2 (en) * | 2008-01-31 | 2012-02-21 | Bausch & Lomb Incorporated | Ophthalmic compositions with an amphoteric surfactant and hyaluronic acid |
| KR20100133980A (ko) * | 2008-03-07 | 2010-12-22 | 썬 파마 어드밴스트 리서치 컴패니 리미티드 | 안약 조성물 |
| US8629099B2 (en) * | 2008-03-25 | 2014-01-14 | Bausch & Lomb Incorporated | Ophthalmic compositions comprising a dipeptide |
| US20100286010A1 (en) * | 2008-09-03 | 2010-11-11 | Erning Xia | Ophthalmic Compositions with Hyaluronic Acid |
| US20100178317A1 (en) * | 2009-01-09 | 2010-07-15 | Burke Susan E | Lens Care Solutions with Hyaluronic Acid |
| US20110293549A1 (en) | 2009-02-03 | 2011-12-01 | Athena Cosmetics, Inc. | Composition, method and kit for enhancing hair |
| WO2011018800A2 (en) * | 2009-08-13 | 2011-02-17 | Fdc Limited | A novel in-situ gel forming solution for ocular drug delivery |
| CN104039307A (zh) * | 2011-04-22 | 2014-09-10 | 爱尔康研究有限公司 | 具有包含两种不同粘度增强剂的粘度增强体系的眼用组合物 |
| PT2787969T (pt) * | 2011-12-07 | 2021-11-09 | Allergan Inc | Entrega eficiente de lípidos para o filme lacrimal humano utilizando um sistema de emulsão sensível ao sal |
| US8664180B2 (en) | 2012-02-06 | 2014-03-04 | Bausch & Lomb Incorporated | Ophthalmic compositions containing diglycine |
| US8324171B1 (en) | 2012-02-06 | 2012-12-04 | Bausch & Lomb Incorporated | Ophthalmic compositions containing diglycine |
| UA113434C2 (uk) * | 2012-05-04 | 2017-01-25 | Алкон Рісерч, Лтд. | Офтальмологічна композиція з поліпшеним захистом від зневоднювання й утриманням |
| PT4082531T (pt) | 2015-01-26 | 2023-12-14 | Bausch & Lomb | Composição de suspensão oftálmica |
| CN108367026A (zh) * | 2015-06-18 | 2018-08-03 | 常规制药股份公司 | 抗微生物配制品 |
| TW201726127A (zh) * | 2016-01-29 | 2017-08-01 | 參天製藥股份有限公司 | 含有多佐胺、高分子及硼酸之醫藥組成物 |
| CN109069421B (zh) * | 2016-04-22 | 2021-10-12 | 乐敦制药株式会社 | 眼科组合物 |
| US11331390B2 (en) | 2016-04-22 | 2022-05-17 | Rohto Pharmaceutical Co., Ltd. | Ophthalmic composition |
| WO2018033792A2 (en) * | 2016-08-19 | 2018-02-22 | Orasis Pharmaceuticals Ltd. | Ophthalmic pharmaceutical compositions and uses relating thereto |
| JP7526718B2 (ja) * | 2019-02-27 | 2024-08-01 | 参天製薬株式会社 | ジクアホソルまたはその塩、ビニル系高分子およびセルロース系高分子を含有する眼科用組成物 |
| WO2024180453A1 (en) * | 2023-02-28 | 2024-09-06 | Alcon Inc. | Dissolvable polymeric eye inserts with a non-ionic cellulose derivative |
| WO2024180472A1 (en) * | 2023-02-28 | 2024-09-06 | Alcon Inc. | Ocular inserts |
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| US7947295B2 (en) * | 2003-06-13 | 2011-05-24 | Alcon, Inc. | Ophthalmic compositions containing a synergistic combination of two polymers |
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-
2004
- 2004-06-06 KR KR1020057023409A patent/KR101147046B1/ko not_active Expired - Fee Related
- 2004-06-06 JP JP2006533590A patent/JP4860475B2/ja not_active Expired - Lifetime
- 2004-06-06 CA CA2839928A patent/CA2839928C/en not_active Expired - Fee Related
- 2004-06-06 KR KR1020127008027A patent/KR20120062846A/ko not_active Ceased
- 2004-06-06 PT PT91689208T patent/PT2116227E/pt unknown
- 2004-06-06 CA CA2839898A patent/CA2839898C/en not_active Expired - Fee Related
- 2004-06-06 AU AU2004249137A patent/AU2004249137B2/en not_active Ceased
- 2004-06-06 CN CNB2004800159648A patent/CN100475192C/zh not_active Expired - Lifetime
- 2004-06-06 KR KR1020117005797A patent/KR101131056B1/ko not_active Expired - Fee Related
- 2004-06-06 CA CA2839847A patent/CA2839847C/en not_active Expired - Fee Related
- 2004-06-06 KR KR1020117018563A patent/KR20110098863A/ko not_active Ceased
- 2004-06-06 KR KR1020117028334A patent/KR20110134525A/ko not_active Ceased
- 2004-06-06 CA CA2839849A patent/CA2839849C/en not_active Expired - Fee Related
- 2004-06-06 CA CA2839930A patent/CA2839930C/en not_active Expired - Fee Related
- 2004-06-06 CA CA2527712A patent/CA2527712C/en not_active Expired - Fee Related
- 2004-06-08 PL PL09168920T patent/PL2116227T3/pl unknown
- 2004-06-08 EP EP09168920.8A patent/EP2116227B1/en not_active Expired - Lifetime
- 2004-06-08 EP EP04754624A patent/EP1631257A2/en not_active Withdrawn
- 2004-06-08 DK DK09168920.8T patent/DK2116227T3/da active
- 2004-06-08 BR BRPI0411361A patent/BRPI0411361B1/pt not_active IP Right Cessation
- 2004-06-08 MX MXPA05013290A patent/MXPA05013290A/es active IP Right Grant
- 2004-06-08 ES ES12173896T patent/ES2570856T3/es not_active Expired - Lifetime
- 2004-06-08 US US10/863,169 patent/US7709012B2/en active Active
- 2004-06-08 ES ES09168920T patent/ES2415738T3/es not_active Expired - Lifetime
- 2004-06-08 SI SI200432047T patent/SI2116227T1/sl unknown
- 2004-06-08 EP EP16153017.5A patent/EP3028692B1/en not_active Expired - Lifetime
- 2004-06-08 EP EP12173896.7A patent/EP2526929B1/en not_active Revoked
- 2004-06-08 ES ES11163662T patent/ES2410505T3/es not_active Expired - Lifetime
- 2004-06-08 WO PCT/US2004/018068 patent/WO2004112836A2/en not_active Ceased
- 2004-06-08 ZA ZA200509440A patent/ZA200509440B/en unknown
- 2004-06-08 EP EP11163662.7A patent/EP2361610B1/en not_active Expired - Lifetime
-
2010
- 2010-01-27 AU AU2010200297A patent/AU2010200297B2/en not_active Ceased
- 2010-11-11 JP JP2010253316A patent/JP2011026354A/ja active Pending
-
2011
- 2011-06-22 JP JP2011138663A patent/JP2011184463A/ja active Pending
-
2013
- 2013-02-22 JP JP2013032842A patent/JP2013100360A/ja active Pending
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