WO2009028674A1 - ラタノプロスト含有水性医薬組成物 - Google Patents

ラタノプロスト含有水性医薬組成物 Download PDF

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Publication number
WO2009028674A1
WO2009028674A1 PCT/JP2008/065564 JP2008065564W WO2009028674A1 WO 2009028674 A1 WO2009028674 A1 WO 2009028674A1 JP 2008065564 W JP2008065564 W JP 2008065564W WO 2009028674 A1 WO2009028674 A1 WO 2009028674A1
Authority
WO
WIPO (PCT)
Prior art keywords
latanoprost
pharmaceutical composition
containing aqueous
aqueous pharmaceutical
filter
Prior art date
Application number
PCT/JP2008/065564
Other languages
English (en)
French (fr)
Inventor
Kohei Yoda
Satoshi Yamazaki
Emi Kawaguchi
Original Assignee
Wakamoto Pharmaceutical Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wakamoto Pharmaceutical Co., Ltd. filed Critical Wakamoto Pharmaceutical Co., Ltd.
Priority to US12/674,962 priority Critical patent/US9456980B2/en
Priority to EP08828329.6A priority patent/EP2193795B1/en
Priority to DK08828329.6T priority patent/DK2193795T3/da
Priority to KR1020107005330A priority patent/KR101529093B1/ko
Priority to ES08828329.6T priority patent/ES2511840T3/es
Priority to JP2009530211A priority patent/JP5327809B2/ja
Publication of WO2009028674A1 publication Critical patent/WO2009028674A1/ja

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Abstract

　フィルター付き容器に充填された、ラタノプロスト含有水性医薬組成物であって、ラタノプロストのフィルターへの吸着が抑制された水性医薬組成物を提供する。 　フィルター付き容器に封入され、ラタノプロストを含有する水性医薬組成物において、非イオン性界面活性剤を含有すること、及びフィルターの材質が、ポリエーテルスルホン、ポリビニリデンフロライド、ポリカーボネート、及びポリテトラフルオロエチレンからなる群から選ばれる少なくとも１種であることを特徴とする水性医薬組成物。
PCT/JP2008/065564 2007-08-29 2008-08-29 ラタノプロスト含有水性医薬組成物 WO2009028674A1 (ja)

Priority Applications (6)

Application Number Priority Date Filing Date Title
US12/674,962 US9456980B2 (en) 2007-08-29 2008-08-29 Latanoprost-containing aqueous pharmaceutical composition
EP08828329.6A EP2193795B1 (en) 2007-08-29 2008-08-29 Latanoprost-containing aqueous pharmaceutical composition
DK08828329.6T DK2193795T3 (da) 2007-08-29 2008-08-29 Latanoprostholdig vandig farmaceutisk sammensætning
KR1020107005330A KR101529093B1 (ko) 2007-08-29 2008-08-29 라타노프로스트 함유 수성 의약 조성물
ES08828329.6T ES2511840T3 (es) 2007-08-29 2008-08-29 Composición farmacéutica acuosa que contiene latanoprost
JP2009530211A JP5327809B2 (ja) 2007-08-29 2008-08-29 ラタノプロスト含有水性医薬組成物

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2007-222316 2007-08-29
JP2007222316 2007-08-29
JP2008002673 2008-01-10
JP2008-002673 2008-01-10

Publications (1)

Publication Number Publication Date
WO2009028674A1 true WO2009028674A1 (ja) 2009-03-05

Family

ID=40387384

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/065564 WO2009028674A1 (ja) 2007-08-29 2008-08-29 ラタノプロスト含有水性医薬組成物

Country Status (8)

Country Link
US (1) US9456980B2 (ja)
EP (1) EP2193795B1 (ja)
JP (1) JP5327809B2 (ja)
KR (1) KR101529093B1 (ja)
DK (1) DK2193795T3 (ja)
ES (1) ES2511840T3 (ja)
PT (1) PT2193795E (ja)
WO (1) WO2009028674A1 (ja)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010119305A1 (en) * 2009-04-14 2010-10-21 Abdi Ibrahim Ilac Sanayi Ve Ticaret Anonim Sirketi Using of quaternary ammonium compounds in dissolving of latanoprost
WO2012141334A1 (en) * 2011-04-12 2012-10-18 R-Tech Ueno, Ltd. Aqueous ophthalmic composition
JP2013213052A (ja) * 2012-02-27 2013-10-17 Rohto Pharmaceutical Co Ltd 眼科用組成物キット
JP2019535713A (ja) * 2016-11-09 2019-12-12 テジュン ファーマシューティカル カンパニー リミテッドＴａｅｊｏｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌ Ｃｏ．， Ｌｔｄ． 眼圧降下用点眼組成物

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2452669A1 (en) 2010-10-29 2012-05-16 Omnivision GmbH Ophthalmic composition
EP2887923B1 (en) 2012-08-24 2023-04-05 Sun Pharmaceutical Industries Limited Ophthalmic formulation of polyoxyl lipid or polyoxyl fatty acid and treatment of ocular conditions
EP3145549A4 (en) * 2014-05-23 2018-02-14 Ocular Technologies Sàrl Topical formulations and uses thereof
PT3373976T (pt) 2015-11-10 2024-04-02 Sun Pharmaceutical Ind Ltd Formulações tópicas e suas utilizações
WO2017151657A1 (en) 2016-02-29 2017-09-08 Ocular Technologies Sarl Topical cyclosporine-containing formulations and uses thereof
CA3104060A1 (en) * 2018-07-09 2020-01-16 Warszawskie Zaklady Farmaceutyczne Polfa Sa Ophthalmic dispensing device

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002520368A (ja) * 1998-07-14 2002-07-09 アルコン ラボラトリーズ， インコーポレイテッド プロスタグランジン製品
JP2005160972A (ja) * 2003-11-10 2005-06-23 Rohto Pharmaceut Co Ltd 眼科用液剤入り容器及び眼科用液剤
JP2006503913A (ja) * 2002-10-24 2006-02-02 スキャンポ・アーゲー・（ユーエスエイ）・インク 高眼圧症および緑内障の処置のための方法およびラタノプロスト含有組成物
JP2007511295A (ja) * 2003-11-14 2007-05-10 メディカル・インスティル・テクノロジーズ・インコーポレイテッド 注入装置及び注入方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE189772T1 (de) 1993-04-16 2000-03-15 Wakamoto Pharma Co Ltd Unter wärmeeinwirkung reversibel gelierende medizinische zusammensetzung auf wasserbasis
JP2729859B2 (ja) 1993-04-16 1998-03-18 わかもと製薬株式会社 可逆性熱ゲル化水性医薬組成物
US6235781B1 (en) 1998-07-14 2001-05-22 Alcon Laboratories, Inc. Prostaglandin product
JP3876355B2 (ja) 2000-09-13 2007-01-31 参天製薬株式会社 点眼液
JP2003095924A (ja) 2001-07-16 2003-04-03 Wakamoto Pharmaceut Co Ltd 熱ゲル化人工涙液
AU2003220987A1 (en) 2002-04-04 2003-10-20 Nipro Corporation Chemical container
JP4357159B2 (ja) 2002-07-22 2009-11-04 ニプロ株式会社 薬液容器
JP4744775B2 (ja) 2002-11-20 2011-08-10 ニプロ株式会社 薬液容器
JP2004123729A (ja) * 2002-09-09 2004-04-22 Santen Pharmaceut Co Ltd ラタノプロストを有効成分とする澄明な点眼液
CA2498233C (en) * 2002-09-09 2012-08-14 Santen Pharmaceutical Co., Ltd. Clear ophthalmic solution comprising latanoprost as active ingredient
US7947295B2 (en) 2003-06-13 2011-05-24 Alcon, Inc. Ophthalmic compositions containing a synergistic combination of two polymers
KR101147046B1 (ko) 2003-06-13 2012-05-22 알콘, 인코퍼레이티드 시너지성의 2개의 폴리머 배합물을 포함하는 안과용 조성물
SG145781A1 (en) * 2003-09-02 2008-09-29 Otsuka Pharma Co Ltd Delivery device, delivery container, and eye dropper provided with the same
EP1681065A4 (en) 2003-10-31 2011-12-28 Wakamoto Pharma Co Ltd WATER-BASED COMPOSITION SUBJECTED TO REVERSIBLE THERMOREGULATION
US20050287325A1 (en) * 2004-06-25 2005-12-29 Pharmacia & Upjohn Company Pharmaceutical containers with low adsorption/absorption of active ingredients, and a method of testing materials for adsorption/absorption of active ingredients

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002520368A (ja) * 1998-07-14 2002-07-09 アルコン ラボラトリーズ， インコーポレイテッド プロスタグランジン製品
JP2006503913A (ja) * 2002-10-24 2006-02-02 スキャンポ・アーゲー・（ユーエスエイ）・インク 高眼圧症および緑内障の処置のための方法およびラタノプロスト含有組成物
JP2005160972A (ja) * 2003-11-10 2005-06-23 Rohto Pharmaceut Co Ltd 眼科用液剤入り容器及び眼科用液剤
JP2007511295A (ja) * 2003-11-14 2007-05-10 メディカル・インスティル・テクノロジーズ・インコーポレイテッド 注入装置及び注入方法

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010119305A1 (en) * 2009-04-14 2010-10-21 Abdi Ibrahim Ilac Sanayi Ve Ticaret Anonim Sirketi Using of quaternary ammonium compounds in dissolving of latanoprost
WO2012141334A1 (en) * 2011-04-12 2012-10-18 R-Tech Ueno, Ltd. Aqueous ophthalmic composition
CN103596572A (zh) * 2011-04-12 2014-02-19 株式会社·R-技术上野 水性眼用组合物
JP2013213052A (ja) * 2012-02-27 2013-10-17 Rohto Pharmaceutical Co Ltd 眼科用組成物キット
JP2019535713A (ja) * 2016-11-09 2019-12-12 テジュン ファーマシューティカル カンパニー リミテッドＴａｅｊｏｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌ Ｃｏ．， Ｌｔｄ． 眼圧降下用点眼組成物
JP7058650B2 (ja) 2016-11-09 2022-04-22 テジュン ファーマシューティカル カンパニー リミテッド 眼圧降下用点眼組成物

Also Published As

Publication number Publication date
JPWO2009028674A1 (ja) 2010-12-02
US9456980B2 (en) 2016-10-04
KR101529093B1 (ko) 2015-06-16
DK2193795T3 (da) 2014-11-03
KR20100056499A (ko) 2010-05-27
ES2511840T3 (es) 2014-10-23
EP2193795B1 (en) 2014-10-01
US20110065790A1 (en) 2011-03-17
EP2193795A4 (en) 2013-09-18
PT2193795E (pt) 2014-10-22
JP5327809B2 (ja) 2013-10-30
EP2193795A1 (en) 2010-06-09

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