ES2570856T3 - Composiciones oftálmicas que contienen una combinación sinérgica de dos polímeros - Google Patents

Composiciones oftálmicas que contienen una combinación sinérgica de dos polímeros

Info

Publication number
ES2570856T3
ES2570856T3 ES12173896T ES12173896T ES2570856T3 ES 2570856 T3 ES2570856 T3 ES 2570856T3 ES 12173896 T ES12173896 T ES 12173896T ES 12173896 T ES12173896 T ES 12173896T ES 2570856 T3 ES2570856 T3 ES 2570856T3
Authority
ES
Spain
Prior art keywords
polymers
compositions containing
synergistic combination
ophthalmic compositions
combination
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES12173896T
Other languages
English (en)
Inventor
Masood A Chowhan
Huagang Chen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=33539082&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2570856(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis AG filed Critical Novartis AG
Application granted granted Critical
Publication of ES2570856T3 publication Critical patent/ES2570856T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Abstract

Una composición acuosa para su uso en el tratamiento del ojo seco mediante administración oftálmica tópica, que comprende una cantidad que mejora la viscosidad de una combinación de dos polímeros que tiene un efecto sinérgico sobre la viscosidad de la composición y en donde la combinación de dos polímeros se selecciona del grupo que consiste en hidroxipropilmetilcelulosa y ácido hialurónico o hidroxietilcelulosa, en donde la concentración de hidroxipropil metilcelulosa oscila entre el 0,05-0,5 % (p/v).
ES12173896T 2003-06-13 2004-06-08 Composiciones oftálmicas que contienen una combinación sinérgica de dos polímeros Active ES2570856T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US47825303P 2003-06-13 2003-06-13

Publications (1)

Publication Number Publication Date
ES2570856T3 true ES2570856T3 (es) 2016-05-20

Family

ID=33539082

Family Applications (3)

Application Number Title Priority Date Filing Date
ES12173896T Active ES2570856T3 (es) 2003-06-13 2004-06-08 Composiciones oftálmicas que contienen una combinación sinérgica de dos polímeros
ES09168920T Active ES2415738T3 (es) 2003-06-13 2004-06-08 Composiciones oftálmicas que contienen una combinación sinérgica de dos polímeros
ES11163662T Active ES2410505T3 (es) 2003-06-13 2004-06-08 Composiciones oftálmicas que contienen una combinación sinérgica de dos polímeros

Family Applications After (2)

Application Number Title Priority Date Filing Date
ES09168920T Active ES2415738T3 (es) 2003-06-13 2004-06-08 Composiciones oftálmicas que contienen una combinación sinérgica de dos polímeros
ES11163662T Active ES2410505T3 (es) 2003-06-13 2004-06-08 Composiciones oftálmicas que contienen una combinación sinérgica de dos polímeros

Country Status (16)

Country Link
US (1) US7709012B2 (es)
EP (5) EP3028692B1 (es)
JP (4) JP4860475B2 (es)
KR (5) KR101131056B1 (es)
CN (1) CN100475192C (es)
AU (2) AU2004249137B2 (es)
BR (1) BRPI0411361B1 (es)
CA (6) CA2839849C (es)
DK (1) DK2116227T3 (es)
ES (3) ES2570856T3 (es)
MX (1) MXPA05013290A (es)
PL (1) PL2116227T3 (es)
PT (1) PT2116227E (es)
SI (1) SI2116227T1 (es)
WO (1) WO2004112836A2 (es)
ZA (1) ZA200509440B (es)

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US8759321B2 (en) * 2007-06-13 2014-06-24 Bausch & Lomb Incorporated Ophthalmic composition with hyaluronic acid and polymeric biguanide
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US8629099B2 (en) * 2008-03-25 2014-01-14 Bausch & Lomb Incorporated Ophthalmic compositions comprising a dipeptide
US20100286010A1 (en) * 2008-09-03 2010-11-11 Erning Xia Ophthalmic Compositions with Hyaluronic Acid
US20100178317A1 (en) * 2009-01-09 2010-07-15 Burke Susan E Lens Care Solutions with Hyaluronic Acid
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WO2012145460A2 (en) * 2011-04-22 2012-10-26 Alcon Research, Ltd. Ophthalmic composition with a viscosity enhancement system having two different viscosity enhancing agents
KR102017922B1 (ko) * 2011-12-07 2019-09-03 알러간, 인코포레이티드 염-민감성 유액 시스템을 사용한 사람 눈물막으로의 효율적인 지질 전달 방법
US8664180B2 (en) 2012-02-06 2014-03-04 Bausch & Lomb Incorporated Ophthalmic compositions containing diglycine
US8324171B1 (en) 2012-02-06 2012-12-04 Bausch & Lomb Incorporated Ophthalmic compositions containing diglycine
UA113434C2 (uk) * 2012-05-04 2017-01-25 Алкон Рісерч, Лтд. Офтальмологічна композиція з поліпшеним захистом від зневоднювання й утриманням
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PL3500255T3 (pl) * 2016-08-19 2023-03-13 Orasis Pharmaceuticals Ltd. Farmaceutyczne kompozycje okulistyczne i powiązane z nimi zastosowania
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Also Published As

Publication number Publication date
CN100475192C (zh) 2009-04-08
CA2839847C (en) 2016-03-15
AU2010200297A1 (en) 2010-02-18
CA2839928C (en) 2016-10-04
EP2116227B1 (en) 2013-04-24
CA2839849C (en) 2017-03-07
EP2116227A2 (en) 2009-11-11
KR101131056B1 (ko) 2012-04-23
EP2526929A1 (en) 2012-11-28
JP2011184463A (ja) 2011-09-22
KR20110032007A (ko) 2011-03-29
AU2004249137A1 (en) 2004-12-29
JP2013100360A (ja) 2013-05-23
EP3028692B1 (en) 2020-04-22
KR20110098863A (ko) 2011-09-01
CA2839847A1 (en) 2004-12-29
EP3028692A1 (en) 2016-06-08
AU2010200297B2 (en) 2012-04-26
JP2011026354A (ja) 2011-02-10
ES2415738T3 (es) 2013-07-26
CA2839898C (en) 2017-01-24
KR20060012024A (ko) 2006-02-06
CA2839898A1 (en) 2004-12-29
MXPA05013290A (es) 2006-03-09
DK2116227T3 (da) 2013-05-27
WO2004112836A8 (en) 2013-02-14
EP2116227A3 (en) 2009-12-30
BRPI0411361A (pt) 2006-07-25
WO2004112836A2 (en) 2004-12-29
JP2007500244A (ja) 2007-01-11
KR20110134525A (ko) 2011-12-14
US20040253280A1 (en) 2004-12-16
EP2361610B1 (en) 2013-04-24
CA2839930C (en) 2016-07-05
AU2004249137B2 (en) 2010-03-11
SI2116227T1 (sl) 2013-07-31
EP2526929B1 (en) 2016-04-06
EP2526929A8 (en) 2013-04-10
WO2004112836A3 (en) 2005-06-16
JP4860475B2 (ja) 2012-01-25
EP2361610A1 (en) 2011-08-31
PT2116227E (pt) 2013-06-28
ZA200509440B (en) 2007-04-25
CA2527712C (en) 2014-08-05
PL2116227T3 (pl) 2013-08-30
CN1802147A (zh) 2006-07-12
CA2527712A1 (en) 2004-12-29
KR20120062846A (ko) 2012-06-14
US7709012B2 (en) 2010-05-04
EP1631257A2 (en) 2006-03-08
CA2839849A1 (en) 2004-12-29
CA2839928A1 (en) 2004-12-29
CA2839930A1 (en) 2004-12-29
KR101147046B1 (ko) 2012-05-22
ES2410505T3 (es) 2013-07-02
BRPI0411361B1 (pt) 2017-05-23

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