JP2006524636A5 - - Google Patents
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- Publication number
- JP2006524636A5 JP2006524636A5 JP2006500346A JP2006500346A JP2006524636A5 JP 2006524636 A5 JP2006524636 A5 JP 2006524636A5 JP 2006500346 A JP2006500346 A JP 2006500346A JP 2006500346 A JP2006500346 A JP 2006500346A JP 2006524636 A5 JP2006524636 A5 JP 2006524636A5
- Authority
- JP
- Japan
- Prior art keywords
- nme
- nhme
- nhco
- halo
- oxo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 description 1
- 125000006367 bivalent amino carbonyl group Chemical group [H]N([*:1])C([*:2])=O 0.000 description 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 description 1
- 125000001475 halogen functional group Chemical group 0.000 description 1
- -1 hydroxy, methoxy Chemical group 0.000 description 1
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 description 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0309780 | 2003-04-29 | ||
| GBGB0327748.0A GB0327748D0 (en) | 2003-11-28 | 2003-11-28 | Novel pharmaceuticals |
| PCT/IB2004/001433 WO2004096810A1 (en) | 2003-04-29 | 2004-04-22 | 5,7-diaminopyrazolo`4,3-d!pyrimidines useful in the treatment of hypertension |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007067736A Division JP2007217419A (ja) | 2003-04-29 | 2007-03-16 | 高血圧症の治療に有用な５，７−ジアミノピラゾロ４，３−ジピリミジン類 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2006524636A JP2006524636A (ja) | 2006-11-02 |
| JP2006524636A5 true JP2006524636A5 (OSRAM) | 2007-09-27 |
| JP4015176B2 JP4015176B2 (ja) | 2007-11-28 |
Family
ID=33420887
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006500346A Expired - Fee Related JP4015176B2 (ja) | 2003-04-29 | 2004-04-22 | 高血圧症の治療に有用な５，７−ジアミノピラゾロ４，３−ジピリミジン類 |
| JP2007067736A Pending JP2007217419A (ja) | 2003-04-29 | 2007-03-16 | 高血圧症の治療に有用な５，７−ジアミノピラゾロ４，３−ジピリミジン類 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007067736A Pending JP2007217419A (ja) | 2003-04-29 | 2007-03-16 | 高血圧症の治療に有用な５，７−ジアミノピラゾロ４，３−ジピリミジン類 |
Country Status (31)
| Country | Link |
|---|---|
| US (2) | US7262192B2 (OSRAM) |
| EP (1) | EP1620437B1 (OSRAM) |
| JP (2) | JP4015176B2 (OSRAM) |
| KR (1) | KR100824193B1 (OSRAM) |
| AR (1) | AR044116A1 (OSRAM) |
| AT (1) | ATE433978T1 (OSRAM) |
| AU (1) | AU2004234158B2 (OSRAM) |
| BR (1) | BRPI0409903A (OSRAM) |
| CA (1) | CA2523831C (OSRAM) |
| CL (1) | CL2004000889A1 (OSRAM) |
| CO (1) | CO5640118A2 (OSRAM) |
| CR (1) | CR8051A (OSRAM) |
| DE (1) | DE602004021585D1 (OSRAM) |
| DK (1) | DK1620437T3 (OSRAM) |
| EA (1) | EA008596B1 (OSRAM) |
| EC (1) | ECSP056130A (OSRAM) |
| ES (1) | ES2326119T3 (OSRAM) |
| GE (1) | GEP20084329B (OSRAM) |
| IS (1) | IS8009A (OSRAM) |
| MA (1) | MA27771A1 (OSRAM) |
| MX (1) | MXPA05011643A (OSRAM) |
| NL (1) | NL1026074C2 (OSRAM) |
| NO (1) | NO333850B1 (OSRAM) |
| NZ (1) | NZ542097A (OSRAM) |
| OA (1) | OA13050A (OSRAM) |
| PA (1) | PA8601701A1 (OSRAM) |
| PE (1) | PE20050462A1 (OSRAM) |
| RS (1) | RS20050810A (OSRAM) |
| TW (1) | TWI273908B (OSRAM) |
| UY (1) | UY28290A1 (OSRAM) |
| WO (1) | WO2004096810A1 (OSRAM) |
Families Citing this family (68)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2523831C (en) | 2003-04-29 | 2008-11-18 | Pfizer Inc. | 5,7-diaminopyrazolo[4,3-d]pyrimidines useful in the treatment of hypertension |
| GB0322552D0 (en) * | 2003-09-26 | 2003-10-29 | Astrazeneca Uk Ltd | Therapeutic treatment |
| GB0327323D0 (en) * | 2003-11-24 | 2003-12-31 | Pfizer Ltd | Novel pharmaceuticals |
| US7572799B2 (en) | 2003-11-24 | 2009-08-11 | Pfizer Inc | Pyrazolo[4,3-d]pyrimidines as Phosphodiesterase Inhibitors |
| GB0327319D0 (en) | 2003-11-24 | 2003-12-24 | Pfizer Ltd | Novel pharmaceuticals |
| DK1742950T3 (da) | 2004-04-07 | 2009-03-16 | Pfizer Ltd | Pyrazolo-[4,3-D]-pyrimidiner |
| TW200626155A (en) | 2004-09-20 | 2006-08-01 | Xenon Pharmaceuticals Inc | Heterocyclic derivatives and their use as therapeutic agents |
| JP4958785B2 (ja) | 2004-09-20 | 2012-06-20 | ゼノン・ファーマシューティカルズ・インコーポレイテッド | 複素環誘導体およびステアロイル−ＣｏＡデサチュラーゼインヒビターとしてのそれらの使用 |
| BRPI0515483A (pt) | 2004-09-20 | 2008-07-22 | Xenon Pharmaceuticals Inc | derivados heterocìclicos para o tratamento de doenças mediadas por enzimas estearoil-coa desaturase |
| AU2005286728A1 (en) | 2004-09-20 | 2006-03-30 | Xenon Pharmaceuticals Inc. | Heterocyclic derivatives and their use as mediators of stearoyl-CoA desaturase |
| CA2580855A1 (en) | 2004-09-20 | 2006-03-30 | Xenon Pharmaceuticals Inc. | Heterocyclic derivatives and their use as stearoyl-coa desaturase inhibitors |
| CN101084211A (zh) | 2004-09-20 | 2007-12-05 | 泽农医药公司 | 杂环衍生物及其作为治疗剂的用途 |
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| CA2585557C (en) * | 2004-10-28 | 2009-08-18 | Pharmacia & Upjohn Company Llc | Pyrazolo[4,3-d] pyrimidine derivatives useful as pde-5 inhibitors |
| JP2008525422A (ja) * | 2004-12-23 | 2008-07-17 | ファイザー・プロダクツ・インク | 抗癌剤として有用な複素芳香族誘導体 |
| GB0428250D0 (en) * | 2004-12-23 | 2005-01-26 | Novartis Ag | Organic compounds |
| TWI320783B (en) | 2005-04-14 | 2010-02-21 | Otsuka Pharma Co Ltd | Heterocyclic compound |
| CN101163706A (zh) * | 2005-04-21 | 2008-04-16 | 贝林格尔·英格海姆国际有限公司 | 用于治疗炎性疾病的二氢噻吩并嘧啶 |
| JP2008540335A (ja) * | 2005-04-27 | 2008-11-20 | アストラゼネカ・アクチエボラーグ | ピラゾリル・ピリミジン誘導体の疼痛治療における使用 |
| NZ564187A (en) * | 2005-05-12 | 2010-03-26 | Pfizer | Anhydrous crystalline forms of N-[1-(2-ethoxyethyl)-5-(N-ethyl-N-methylamino)-7-(4-methylpyridin-2-yl-amino)-1H-pyrazolo[4,3-d]pyrimidine-3-carbonyl]methanesulfonamide |
| AP2007004219A0 (en) * | 2005-05-12 | 2007-10-31 | Pfizer | Anhydrous crystalline forms of N-[1-(2-ethoxyethyl)-5-(N-ethyl-N-methylamino)-7-(4-methylpyridin-2-YL-amino)-1H-pyrazolo[4,3-D] pyrimidine-3-carbonyl]methanesulfonamide |
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| EP1847543A1 (de) | 2006-04-19 | 2007-10-24 | Boehringer Ingelheim Pharma GmbH & Co. KG | Dihydrothienopyrimidine zur Behandlung von entzündlichen Erkrankungen |
| BRPI0818006B8 (pt) | 2007-10-19 | 2021-05-25 | Boehringer Ingelheim Int | compostos de piperidino-di-hidrotienopirimidinas substituídas, uso dos mesmos e formulações farmacêuticas |
| JP5563466B2 (ja) | 2007-10-19 | 2014-07-30 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 新規ピペラジノ−ジヒドロチエノピリミジン誘導体 |
| EP2205609B1 (de) | 2007-10-19 | 2017-03-29 | Boehringer Ingelheim International GmbH | Heterocyclus-substituierte piperazino-dihydrothienopyrimidine |
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| WO2009124119A2 (en) * | 2008-04-01 | 2009-10-08 | The Trustes of Columbia University in the City of New York | Phosphodiesterase inhibitors and uses thereof |
| KR101683042B1 (ko) | 2008-04-04 | 2016-12-06 | 포사이트 비젼4, 인크. | 통증 관리 및 시력을 위한 치료 장치 |
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| US12044905B2 (en) | 2011-04-28 | 2024-07-23 | Journey1 Inc | Contact lenses for refractive correction |
| WO2014210186A2 (en) | 2013-06-26 | 2014-12-31 | Nexisvision, Inc. | Contact lenses for refractive correction |
| SI2710005T1 (sl) * | 2011-05-17 | 2017-03-31 | Principia Biopharma Inc. | Zaviralci tirozinske kinaze |
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| JO3753B1 (ar) | 2011-10-14 | 2021-01-31 | Otsuka Pharma Co Ltd | قرص يتألف من 7-[4-(4-بينزو[بي]ثيوفين-4-ايل-ببرازين-1-1ايل)بوتكسيل]-1اتش-كوينولين-2-وان أو ملح منه |
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| US9579288B2 (en) | 2015-03-03 | 2017-02-28 | Saniona A/S | Tesofensine and beta blocker combination formulations |
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| MA46191A (fr) | 2016-09-09 | 2021-04-21 | Incyte Corp | Dérivés de pyrazolopyridine comme modulateurs de hpk1 et leurs utilisations pour le traitement du cancer |
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| US20190167699A1 (en) | 2017-12-01 | 2019-06-06 | Innovus Pharmaceuticals, Inc. | Prostate function support formula |
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| EP1176147A1 (en) | 2000-07-28 | 2002-01-30 | Pfizer Limited | Process for the preparation of pyrazolo[4,3-d]pyrimidin-7-ones and intermediates thereof |
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-
2004
- 2004-04-22 CA CA002523831A patent/CA2523831C/en not_active Expired - Lifetime
- 2004-04-22 JP JP2006500346A patent/JP4015176B2/ja not_active Expired - Fee Related
- 2004-04-22 KR KR1020057020497A patent/KR100824193B1/ko not_active Expired - Fee Related
- 2004-04-22 EP EP04728868A patent/EP1620437B1/en not_active Expired - Lifetime
- 2004-04-22 NZ NZ542097A patent/NZ542097A/en unknown
- 2004-04-22 GE GEAP20049033A patent/GEP20084329B/en unknown
- 2004-04-22 WO PCT/IB2004/001433 patent/WO2004096810A1/en not_active Ceased
- 2004-04-22 ES ES04728868T patent/ES2326119T3/es not_active Expired - Lifetime
- 2004-04-22 AU AU2004234158A patent/AU2004234158B2/en not_active Ceased
- 2004-04-22 DK DK04728868T patent/DK1620437T3/da active
- 2004-04-22 MX MXPA05011643A patent/MXPA05011643A/es active IP Right Grant
- 2004-04-22 RS YUP-2005/0810A patent/RS20050810A/sr unknown
- 2004-04-22 EA EA200501333A patent/EA008596B1/ru not_active IP Right Cessation
- 2004-04-22 OA OA1200500306A patent/OA13050A/en unknown
- 2004-04-22 BR BRPI0409903-6A patent/BRPI0409903A/pt not_active IP Right Cessation
- 2004-04-22 DE DE602004021585T patent/DE602004021585D1/de not_active Expired - Lifetime
- 2004-04-22 AT AT04728868T patent/ATE433978T1/de not_active IP Right Cessation
- 2004-04-26 PE PE2004000411A patent/PE20050462A1/es not_active Application Discontinuation
- 2004-04-27 UY UY28290A patent/UY28290A1/es not_active Application Discontinuation
- 2004-04-27 CL CL200400889A patent/CL2004000889A1/es unknown
- 2004-04-28 TW TW093111926A patent/TWI273908B/zh not_active IP Right Cessation
- 2004-04-28 AR ARP040101440A patent/AR044116A1/es unknown
- 2004-04-28 NL NL1026074A patent/NL1026074C2/nl not_active IP Right Cessation
- 2004-04-29 US US10/834,484 patent/US7262192B2/en not_active Expired - Fee Related
- 2004-04-29 PA PA20048601701A patent/PA8601701A1/es unknown
-
2005
- 2005-08-31 IS IS8009A patent/IS8009A/is unknown
- 2005-09-22 NO NO20054404A patent/NO333850B1/no not_active IP Right Cessation
- 2005-10-20 CR CR8051A patent/CR8051A/es not_active Application Discontinuation
- 2005-10-28 EC EC2005006130A patent/ECSP056130A/es unknown
- 2005-10-28 MA MA28571A patent/MA27771A1/fr unknown
- 2005-10-28 CO CO05110249A patent/CO5640118A2/es not_active Application Discontinuation
-
2007
- 2007-03-16 JP JP2007067736A patent/JP2007217419A/ja active Pending
- 2007-07-31 US US11/831,021 patent/US20070270412A1/en not_active Abandoned
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