|
DE10303974A1
(de)
|
2003-01-31 |
2004-08-05 |
Abbott Gmbh & Co. Kg |
Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung
|
|
EP1628663B1
(en)
*
|
2003-05-15 |
2009-07-29 |
Roskamp Research llc |
Method for producing medicaments for reducing amyloid deposition, amyloid neurotoxicity and microgliosis
|
|
US20070010573A1
(en)
|
2003-06-23 |
2007-01-11 |
Xianqi Kong |
Methods and compositions for treating amyloid-related diseases
|
|
CA2528627A1
(en)
*
|
2003-06-23 |
2005-01-06 |
Neurochem (International) Limited |
Treatment of protein aggregation disorders
|
|
US20050142191A1
(en)
*
|
2003-06-23 |
2005-06-30 |
Neurochem (International) Limited |
Pharmaceutical formulations of amyloid inhibiting compounds
|
|
AU2011250847B2
(en)
*
|
2003-06-23 |
2013-06-20 |
Bhi Limited Partnership |
Methods and compositions for treating amyloid-related diseases
|
|
EP1644325A2
(en)
*
|
2003-06-23 |
2006-04-12 |
Neurochem (International) Limited |
Methods and compositions for treating amyloid-related diseases
|
|
KR20110140139A
(ko)
*
|
2003-08-29 |
2011-12-30 |
오노 야꾸힝 고교 가부시키가이샤 |
S1p 수용체 결합능을 갖는 화합물 및 그 의약 용도
|
|
JP4696079B2
(ja)
|
2003-12-17 |
2011-06-08 |
ヤンセン アルツハイマー イミュノセラピー |
Aβ免疫原性ペプチド担体結合物およびそれの製造方法
|
|
CN1960781A
(zh)
*
|
2004-04-14 |
2007-05-09 |
沃尼尔·朗伯有限责任公司 |
治疗阿尔茨海默氏病的治疗组合
|
|
EP1841460A2
(en)
*
|
2004-06-18 |
2007-10-10 |
Neurochem (International) Limited |
Therapeutic formulations for the treatment of beta-amyloid related diseases
|
|
JP4717537B2
(ja)
*
|
2004-08-31 |
2011-07-06 |
株式会社 資生堂 |
皮膚外用組成物
|
|
EP1828111A2
(en)
*
|
2004-11-12 |
2007-09-05 |
Neurochem (International) Limited |
Methods and fluorinated compositions for treating amyloid-related diseases
|
|
BRPI0519243A2
(pt)
*
|
2004-12-22 |
2009-01-06 |
Neurochem Int Ltd |
mÉtodos e composiÇÕes para tratar doenÇas relacionadas a amilàide
|
|
TW200716088A
(en)
*
|
2005-04-15 |
2007-05-01 |
Neurochem Int Ltd |
Formulations and methods for treating amyloidosis
|
|
US7420071B2
(en)
*
|
2005-05-04 |
2008-09-02 |
Uchicago Argonne, Llc |
Thermally stable surfactants and compositions and methods of use thereof
|
|
US8691224B2
(en)
|
2005-11-30 |
2014-04-08 |
Abbvie Inc. |
Anti-Aβ globulomer 5F7 antibodies
|
|
HRP20140240T4
(hr)
|
2005-11-30 |
2017-02-24 |
Abbvie Inc. |
Monoklonalna antitijela protiv amiloidnih beta proteina i njihova upotreba
|
|
EP1959996A2
(en)
|
2005-12-12 |
2008-08-27 |
AC Immune S.A. |
Monoclonal antibody
|
|
KR101152557B1
(ko)
|
2005-12-12 |
2012-09-07 |
에이씨 이뮨 에스.에이. |
치료 백신
|
|
MX2008008213A
(es)
|
2005-12-22 |
2008-09-03 |
Neurochem Int Ltd |
Tratamiento de trastornos renales, nefropatia diabetica y dislipidemias.
|
|
CA2675230A1
(en)
*
|
2006-01-10 |
2008-07-26 |
Pipex, Inc. |
Pharmaceutical compositions and methods to achieve and maintain a targeted and stable copper status and prevent and treat copper-related central nervous system diseases
|
|
MY153248A
(en)
|
2006-07-14 |
2015-01-29 |
Ac Immune Sa |
Humanized antibody against amyloid beta
|
|
EP2046833B9
(en)
|
2006-07-14 |
2014-02-19 |
AC Immune S.A. |
Humanized antibody against amyloid beta
|
|
DK2089417T3
(en)
*
|
2006-10-12 |
2015-03-23 |
Bhi Ltd Partnership |
Methods, Compounds, Compositions and Vehicles for Delivery of 3-Amion-1-Propanesulfonic Acid
|
|
US8188046B2
(en)
|
2006-10-16 |
2012-05-29 |
University Of South Florida |
Amyloid beta peptides and methods of use
|
|
KR101450356B1
(ko)
|
2006-11-24 |
2014-10-15 |
에이씨 이뮨 에스.에이. |
알츠하이머와 같은 아밀로이드 또는 아밀로이드-유사 단백질과 관련된 질환의 치료를 위한 n-(메틸)-1h-피라졸-3-아민, n-(메틸)-피리딘-2-아민 및 n-(메틸)-티아졸-2-아민 유도체
|
|
US8455626B2
(en)
|
2006-11-30 |
2013-06-04 |
Abbott Laboratories |
Aβ conformer selective anti-aβ globulomer monoclonal antibodies
|
|
GB0701970D0
(en)
*
|
2007-02-01 |
2007-03-14 |
Wilson Stuart |
Treatment of protein aggregation diseases
|
|
US8895004B2
(en)
|
2007-02-27 |
2014-11-25 |
AbbVie Deutschland GmbH & Co. KG |
Method for the treatment of amyloidoses
|
|
US7618944B2
(en)
*
|
2007-03-01 |
2009-11-17 |
Intezyne Technologies, Inc. |
Encapsulated amyloid-beta peptides
|
|
WO2008142560A2
(en)
*
|
2007-05-24 |
2008-11-27 |
Simone Arca |
Method for the production of binary clathrate hydrates of hydrogen
|
|
US8048420B2
(en)
|
2007-06-12 |
2011-11-01 |
Ac Immune S.A. |
Monoclonal antibody
|
|
ES2529174T3
(es)
|
2007-06-12 |
2015-02-17 |
Ac Immune S.A. |
Anticuerpos humanizados para amiloide beta
|
|
NZ581835A
(en)
|
2007-06-12 |
2012-09-28 |
Ac Immune Sa |
Monoclonal anti beta amyloid antibody
|
|
US8613923B2
(en)
|
2007-06-12 |
2013-12-24 |
Ac Immune S.A. |
Monoclonal antibody
|
|
EP2182978A4
(en)
|
2007-07-20 |
2012-03-21 |
Sanomune Inc |
TISSUE KALLIKREIN FOR THE TREATMENT OF DISEASES ASSOCIATED WITH AMYLOID PROTEIN
|
|
EP2044951A1
(en)
|
2007-10-02 |
2009-04-08 |
Merz Pharma GmbH & Co. KGaA |
The use of substances for the treatment of loss of eyesight in humans with glaucoma and other degenerative eye diseases
|
|
NZ584729A
(en)
|
2007-10-05 |
2012-12-21 |
Alzheimer S Inst Of America Inc |
Method for reducing amyloid deposition, amyloid neurotoxicity, and microgliosis with (-)-nilvadipine enantiomer
|
|
AU2008311367B2
(en)
|
2007-10-05 |
2014-11-13 |
Ac Immune S.A. |
Use of anti-amyloid beta antibody in ocular diseases
|
|
BRPI0818623A2
(pt)
|
2007-10-05 |
2017-05-23 |
Ac Immune Sa |
composição farmacêutica, e, métodos para reduzir a carga da placa na camada de célula de gânglio retinal de um animal, para reduzir a quantidade de placas na camada de célula de gânglio retinal de um animal, para diminuir a quantidade total de amilóide-beta solúvel na camada de célula de gânglio retinal de um animal, para prevenir, tratar e/ou aliviar os efeitos de uma doença ocular associada com anormalidades patológicas/mudanças no tecido do sistema visual, para monitorar doença ocular residual mínima associada com anormalidades patológicas/mudanças nos tecidos do sistema visual, para predizer responsividade de um paciente, e para reter ou diminuir a pressão ocular nos olhos de um animal
|
|
WO2009059239A2
(en)
*
|
2007-11-02 |
2009-05-07 |
Mayo Foundation For Medical Education And Research |
REDUCING Aβ42 LEVELS AND Aβ AGGREGATION
|
|
EP2149380A1
(en)
*
|
2008-07-29 |
2010-02-03 |
Medivet Pharma, S.L. |
Veterinary immunotherapy compositions for the Aged Related Cognitive Dysfunction.
|
|
US8846315B2
(en)
|
2008-08-12 |
2014-09-30 |
Zinfandel Pharmaceuticals, Inc. |
Disease risk factors and methods of use
|
|
WO2010042603A1
(en)
*
|
2008-10-08 |
2010-04-15 |
Cingulate Neuro Therapeutics, Llc |
Amyloid and depression
|
|
HUE055739T2
(hu)
|
2009-03-18 |
2021-12-28 |
Ac Immune Sa |
Eljárás terápiás alkalmazásra
|
|
UA107571C2
(xx)
|
2009-04-03 |
2015-01-26 |
|
Фармацевтична композиція
|
|
JP5051274B2
(ja)
|
2009-06-04 |
2012-10-17 |
住友化学株式会社 |
加硫ゴムが有する粘弾性特性を改善させるためのs−(3−アミノプロピル)チオ硫酸および/またはその金属塩の使用
|
|
EP2311823A1
(en)
|
2009-10-15 |
2011-04-20 |
AC Immune S.A. |
2,6-Diaminopyridine compounds for treating diseases associated with amyloid proteins or for treating ocular diseases
|
|
US8987419B2
(en)
|
2010-04-15 |
2015-03-24 |
AbbVie Deutschland GmbH & Co. KG |
Amyloid-beta binding proteins
|
|
AU2011239966B2
(en)
|
2010-04-16 |
2014-05-08 |
Ac Immune S.A. |
Novel compounds for the treatment of diseases associated with amyloid or amyloid-like proteins
|
|
EP2377860A1
(en)
|
2010-04-16 |
2011-10-19 |
AC Immune S.A. |
Novel compounds for the treatment of diseases associated with amyloid or amyloid-like proteins
|
|
EP2598882B1
(en)
|
2010-07-30 |
2017-07-26 |
AC Immune S.A. |
Safe and functional humanized antibodies for use in treating an amyloidosis
|
|
EP3533803B1
(en)
|
2010-08-14 |
2021-10-27 |
AbbVie Inc. |
Anti-amyloid-beta antibodies
|
|
MY164376A
(en)
|
2010-10-07 |
2017-12-15 |
Univ Leuven Kath |
Phosphospecific antibodies recognizing tau
|
|
JP6027011B2
(ja)
|
2010-10-26 |
2016-11-16 |
エーシー イミューン ソシエテ アノニム |
疎水性部分によって修飾されたペプチドを含むリポソームベースの構築物
|
|
US20120328605A1
(en)
*
|
2010-10-27 |
2012-12-27 |
Daniel Larocque |
Compositions and uses
|
|
EA201391017A1
(ru)
|
2011-01-10 |
2014-04-30 |
Зинфандел Фармасьютикалз, Инк. |
Способы и готовые лекарственные формы для лечения болезни альцгеймера
|
|
WO2013009799A1
(en)
*
|
2011-07-11 |
2013-01-17 |
Beth Israel Deaconess Medical Center, Inc. |
Vitamin d receptor agonists and uses thereof
|
|
CA2811188C
(en)
|
2011-09-23 |
2020-04-28 |
Andrea Pfeifer |
Vaccine therapy
|
|
KR101981351B1
(ko)
|
2011-10-07 |
2019-09-02 |
에이씨 이뮨 에스.에이. |
타우를 인식하는 포스포특이적 항체
|
|
RU2644242C2
(ru)
|
2012-04-05 |
2018-02-08 |
Ац Иммуне С.А. |
Гуманизированное тау-антитело
|
|
US20130315891A1
(en)
|
2012-05-25 |
2013-11-28 |
Matthew Charles |
Formulations of human tissue kallikrein-1 for parenteral delivery and related methods
|
|
US20130323222A1
(en)
|
2012-06-04 |
2013-12-05 |
Matthew Charles |
Human tissue kallikrein 1 glycosylation isoforms
|
|
CA3132310C
(en)
*
|
2012-08-07 |
2024-01-09 |
Children's Medical Center Corporation |
Potassium channel openers for treating neurodegenerative diseases
|
|
PL2931276T3
(pl)
*
|
2012-12-13 |
2018-06-29 |
H. Lundbeck A/S |
Kompozycje zawierające wortioksetynę i donepezil
|
|
US9200068B2
(en)
*
|
2012-12-18 |
2015-12-01 |
Regents Of The University Of Minnesota |
Compositions and methods related to tauopathy
|
|
WO2014150877A2
(en)
|
2013-03-15 |
2014-09-25 |
Ac Immune S.A. |
Anti-tau antibodies and methods of use
|
|
WO2015110263A1
(en)
|
2014-01-21 |
2015-07-30 |
Ac Immune Sa |
Carbazole and carboline compounds for use in the diagnosis, treatment, alleviation or prevention of disorders associated with amyloid or amyolid-like proteins
|
|
US10314911B2
(en)
*
|
2014-04-08 |
2019-06-11 |
Healthpartners Research & Education |
Methods for protecting and treating traumatic brain injury, concussion and brain inflammation with intranasal insulin
|
|
KR102298676B1
(ko)
*
|
2014-05-09 |
2021-09-07 |
테크니메데 소시에다데 테크니코-메디시날 에스.에이. |
의약으로서 사용되기 위한 (s)-펄린돌 및 약학적으로 허용 가능한 그의 염
|
|
TN2016000497A1
(en)
*
|
2014-05-09 |
2018-04-04 |
Tecnimede Sociedade Tecnico Medicinal S |
(r)-pirlindole and its pharmaceutically acceptable salts for use in medicine
|
|
CN107428820B
(zh)
|
2014-11-19 |
2022-03-22 |
阿克松神经系统科学公司 |
在阿尔茨海默氏病中的人源化tau抗体
|
|
NZ775762A
(en)
|
2015-06-05 |
2025-02-28 |
Genentech Inc |
Anti-tau antibodies and methods of use
|
|
MX380290B
(es)
|
2015-08-10 |
2025-03-12 |
Alzheon Inc |
Composiciones y métodos para el tratamiento y la prevención de trastornos neurodegenerativos.
|
|
EP3374381A4
(en)
|
2015-11-09 |
2019-05-15 |
The University Of British Columbia |
EPITOPES IN THE AMYLOID-BETA MEDIUM REGION AND CONFORMITY-SELECTIVE ANTIBODIES THEREOF
|
|
AU2016353553B2
(en)
|
2015-11-09 |
2022-01-20 |
The University Of British Columbia |
Amyloid beta epitopes and antibodies thereto
|
|
KR102776187B1
(ko)
|
2015-11-09 |
2025-03-07 |
더 유니버시티 오브 브리티쉬 콜롬비아 |
아밀로이드 베타에서의 n-말단 에피토프 및 이에 형태적으로-선택적인 항체
|
|
ITUA20161679A1
(it)
|
2016-03-15 |
2017-09-15 |
Neuraxpharm Italy S P A |
Composizione per prevenire e trattare patologie neurodegenerative e disturbi cognitivi
|
|
CN109476729A
(zh)
|
2016-07-18 |
2019-03-15 |
英属哥伦比亚大学 |
淀粉样蛋白β的抗体
|
|
WO2018038973A1
(en)
*
|
2016-08-20 |
2018-03-01 |
The Arizona Board Of Regents On Behalf Of The University Of Arizona |
Neuroprotective beta amyloid core peptides and peptidomimetic derivatives
|
|
US20180125920A1
(en)
|
2016-11-09 |
2018-05-10 |
The University Of British Columbia |
Methods for preventing and treating A-beta oligomer-associated and/or -induced diseases and conditions
|
|
MX2019006330A
(es)
|
2016-12-07 |
2019-09-26 |
Genentech Inc |
Anticuerpos anti-tau y metodos de uso.
|
|
UA128383C2
(uk)
|
2016-12-07 |
2024-07-03 |
Дженентек, Інк. |
Антитіло до тау-білка та спосіб його застосування
|
|
AU2018230478B2
(en)
|
2017-03-09 |
2025-01-23 |
Diamedica Inc. |
Dosage forms of tissue kallikrein 1
|
|
EP3601337A1
(en)
|
2017-03-28 |
2020-02-05 |
Genentech, Inc. |
Methods of treating neurodegenerative diseases
|
|
AU2018260628A1
(en)
*
|
2017-04-25 |
2019-12-12 |
Temple Otorongo Llc |
Pharmaceutical composition comprising tryptophan and phyllokinin derivative for use in treating psychiatric and psychological conditions
|
|
KR101917128B1
(ko)
|
2017-04-28 |
2018-11-09 |
강원대학교산학협력단 |
산양삼 추출물을 포함하는 알츠하이머병의 예방 또는 치료용 약학 조성물
|
|
WO2019018445A1
(en)
*
|
2017-07-17 |
2019-01-24 |
Maxwell Biosciences, Inc. |
POLYTHERAPY MODULATING THE MODULATION OF CATHELICIDINE GENE EXPRESSION FOR THE TREATMENT OF ALZHEIMER'S DISEASE AND OTHER DISEASES
|
|
US12286469B2
(en)
|
2017-07-18 |
2025-04-29 |
The University Of British Columbia |
Humanized antibodies binding to amyloid-beta (A-beta)
|
|
US12459965B2
(en)
|
2017-10-09 |
2025-11-04 |
Compass Pathfinder Limited |
Preparation of psilocybin, different polymorphic forms, intermediates, formulations and their use
|
|
GB2571696B
(en)
|
2017-10-09 |
2020-05-27 |
Compass Pathways Ltd |
Large scale method for the preparation of Psilocybin and formulations of Psilocybin so produced
|
|
US20200330592A1
(en)
*
|
2017-10-09 |
2020-10-22 |
Keith Black |
Compositions and methods of treating alzheimer's and other amyloid related diseases
|
|
CN111787942B
(zh)
|
2017-10-25 |
2024-03-29 |
杨森制药公司 |
磷酸化Tau肽的组合物及其用途
|
|
PE20211090A1
(es)
|
2018-01-05 |
2021-06-14 |
Ac Immune Sa |
Derivados de 1,3,4,5-tetrahidro-2h-pirido[4,3-b]indol para el tratamiento, alivio o prevencion de trastornos asociados con los agregados de tau
|
|
SG11202008098TA
(en)
|
2018-03-28 |
2020-10-29 |
Axon Neuroscience Se |
Antibody-based methods of detecting and treating alzheimer's disease
|
|
CN112351984B
(zh)
|
2018-06-04 |
2024-01-02 |
Ac免疫有限公司 |
用于治疗、缓解或预防与Tau聚集物相关病症的四氢苯并呋喃并[2.3-c]吡啶和β-咔啉化合物
|
|
CN112313230B
(zh)
|
2018-06-04 |
2024-03-15 |
Ac免疫有限公司 |
用于治疗、缓解或预防与Tau聚集体相关的病症的新型化合物
|
|
KR20200086198A
(ko)
|
2019-01-08 |
2020-07-16 |
주식회사 솔고 바이오메디칼 |
수소 흡장 금속을 포함하는 치매 예방 또는 치료용 조성물
|
|
WO2020150423A1
(en)
*
|
2019-01-16 |
2020-07-23 |
Yumanity Therapeutics, Inc. |
Methods for the treatment of neurological disorders
|
|
MY206596A
(en)
|
2019-02-08 |
2024-12-25 |
Janssen Pharmaceuticals Inc |
Method of safe administration of phosphorylated tau peptide vaccine
|
|
JP7232931B2
(ja)
|
2019-03-01 |
2023-03-03 |
エイシー イミューン ソシエテ アノニム |
タウ凝集体に関連する障害の治療、緩和、または予防のための新規化合物
|
|
US12377112B2
(en)
|
2019-04-17 |
2025-08-05 |
Compass Pathfinder Limited |
Methods of treating neurocognitive disorders, chronic pain and reducing inflammation
|
|
JP7327788B2
(ja)
*
|
2019-08-06 |
2023-08-16 |
学校法人福岡大学 |
糖化産物生成抑制剤及び医薬組成物
|
|
US12352719B2
(en)
|
2019-09-20 |
2025-07-08 |
KYCERA AVX Components Corporation |
Somatic cell-based electrical biosensor
|
|
WO2021067850A2
(en)
*
|
2019-10-02 |
2021-04-08 |
Washington University |
METHODS OF DETECTING circRNA
|
|
ES2821599A1
(es)
|
2019-10-24 |
2021-04-26 |
Univ Del Pais Vasco / Euskal Herriko Unibertsitatea |
Compuestos y metodos para el tratamiento de la enfermedad de alzheimer
|
|
CN112939823A
(zh)
*
|
2019-12-10 |
2021-06-11 |
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