|
DE10303974A1
(de)
|
2003-01-31 |
2004-08-05 |
Abbott Gmbh & Co. Kg |
Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung
|
|
CA2525970C
(en)
|
2003-05-15 |
2011-03-22 |
Roskamp Research, Llc |
Use of nilvadipine for reducing amyloid deposition, amyloid neurotoxicity and microgliosis
|
|
EP1646375A2
(en)
*
|
2003-06-23 |
2006-04-19 |
Neurochem (International) Limited |
Treatment of protein aggregation disorders
|
|
US20070010573A1
(en)
|
2003-06-23 |
2007-01-11 |
Xianqi Kong |
Methods and compositions for treating amyloid-related diseases
|
|
AU2011250847B2
(en)
*
|
2003-06-23 |
2013-06-20 |
Bhi Limited Partnership |
Methods and compositions for treating amyloid-related diseases
|
|
US20050142191A1
(en)
|
2003-06-23 |
2005-06-30 |
Neurochem (International) Limited |
Pharmaceutical formulations of amyloid inhibiting compounds
|
|
JP5146714B2
(ja)
*
|
2003-06-23 |
2013-02-20 |
ビーエイチアイ リミテッド パートナーシップ |
アミロイド関連疾患を治療するための方法および組成物
|
|
EP1661881B1
(en)
*
|
2003-08-29 |
2014-12-17 |
Ono Pharmaceutical Co., Ltd. |
Compound capable of binding s1p receptor and pharmaceutical use thereof
|
|
EP2336147B1
(en)
|
2003-12-17 |
2014-04-30 |
Janssen Alzheimer Immunotherapy |
A beta immunogenic peptide carrier conjugates and methods of producing same
|
|
MXPA06011969A
(es)
*
|
2004-04-14 |
2006-12-15 |
Warner Lambert Co |
Combinacion terapeutica para tratamiento de la enfermedad de alzheimer.
|
|
EP1841460A2
(en)
*
|
2004-06-18 |
2007-10-10 |
Neurochem (International) Limited |
Therapeutic formulations for the treatment of beta-amyloid related diseases
|
|
JP4717537B2
(ja)
*
|
2004-08-31 |
2011-07-06 |
株式会社 資生堂 |
皮膚外用組成物
|
|
US20060183800A1
(en)
*
|
2004-11-12 |
2006-08-17 |
Xianqi Kong |
Methods and fluorinated compositions for treating amyloid-related diseases
|
|
WO2006085149A2
(en)
|
2004-12-22 |
2006-08-17 |
Neurochem (International) Limited |
Methods and compositions for treating amyloid-related diseases
|
|
TW200716088A
(en)
*
|
2005-04-15 |
2007-05-01 |
Neurochem Int Ltd |
Formulations and methods for treating amyloidosis
|
|
US7420071B2
(en)
*
|
2005-05-04 |
2008-09-02 |
Uchicago Argonne, Llc |
Thermally stable surfactants and compositions and methods of use thereof
|
|
PL2289909T3
(pl)
|
2005-11-30 |
2015-04-30 |
Abbvie Inc |
Sposób przeszukiwania, proces oczyszczania niedyfundujących oligomerów Abeta, selektywne przeciwciała przeciw niedyfundującym oligomerom Abeta i sposób wytwarzania tych przeciwciał
|
|
RU2432362C2
(ru)
|
2005-11-30 |
2011-10-27 |
Эбботт Лэборетриз |
Моноклональные антитела и их применения
|
|
SG10201404801YA
(en)
|
2005-12-12 |
2014-09-26 |
Ac Immune Sa |
Monoclonal antibody
|
|
CA2633399C
(en)
|
2005-12-12 |
2016-01-26 |
Ac Immune S.A. |
Therapeutic vaccine
|
|
EP1968561B8
(en)
|
2005-12-22 |
2010-10-20 |
Kiacta Sàrl |
Treatment of diabetic nephropathy
|
|
CA2675230A1
(en)
*
|
2006-01-10 |
2008-07-26 |
Pipex, Inc. |
Pharmaceutical compositions and methods to achieve and maintain a targeted and stable copper status and prevent and treat copper-related central nervous system diseases
|
|
LT2468770T
(lt)
|
2006-07-14 |
2018-05-25 |
Ac Immune S.A. |
Humanizuotas antikūnas prieš beta amiloidą
|
|
NZ574188A
(en)
|
2006-07-14 |
2012-05-25 |
Ac Immune Sa |
Humanized antibody against amyloid beta
|
|
PT2089417E
(pt)
|
2006-10-12 |
2015-04-14 |
Bhi Ltd Partnership |
Métodos, compostos, composições e veículos para administrar o ácido 3-amino-1-propanossulfónico
|
|
US8188046B2
(en)
|
2006-10-16 |
2012-05-29 |
University Of South Florida |
Amyloid beta peptides and methods of use
|
|
CN102838532A
(zh)
|
2006-11-24 |
2012-12-26 |
Ac免疫有限公司 |
用于治疗与淀粉样物质或淀粉样蛋白有关的疾病的吡唑胺和噻唑胺衍生物
|
|
US8455626B2
(en)
|
2006-11-30 |
2013-06-04 |
Abbott Laboratories |
Aβ conformer selective anti-aβ globulomer monoclonal antibodies
|
|
GB0701970D0
(en)
*
|
2007-02-01 |
2007-03-14 |
Wilson Stuart |
Treatment of protein aggregation diseases
|
|
EP2124952A2
(en)
|
2007-02-27 |
2009-12-02 |
Abbott GmbH & Co. KG |
Method for the treatment of amyloidoses
|
|
US7618944B2
(en)
*
|
2007-03-01 |
2009-11-17 |
Intezyne Technologies, Inc. |
Encapsulated amyloid-beta peptides
|
|
EP2160352A2
(en)
*
|
2007-05-24 |
2010-03-10 |
Simone Arca |
Method for the production of binary clathrate hydrates of hydrogen
|
|
PL2170389T3
(pl)
|
2007-06-12 |
2015-03-31 |
Ac Immune Sa |
Humanizowane przeciwciało przeciw amyloidowi beta
|
|
EP2527366B1
(en)
|
2007-06-12 |
2017-08-16 |
AC Immune S.A. |
Monoclonal anti beta amyloid antibody
|
|
US8613923B2
(en)
|
2007-06-12 |
2013-12-24 |
Ac Immune S.A. |
Monoclonal antibody
|
|
US8048420B2
(en)
|
2007-06-12 |
2011-11-01 |
Ac Immune S.A. |
Monoclonal antibody
|
|
EP2182978A4
(en)
|
2007-07-20 |
2012-03-21 |
Sanomune Inc |
TISSUE KALLIKREIN FOR THE TREATMENT OF DISEASES ASSOCIATED WITH AMYLOID PROTEIN
|
|
EP2044951A1
(en)
|
2007-10-02 |
2009-04-08 |
Merz Pharma GmbH & Co. KGaA |
The use of substances for the treatment of loss of eyesight in humans with glaucoma and other degenerative eye diseases
|
|
TWI500422B
(zh)
|
2007-10-05 |
2015-09-21 |
Alzheimer S Inst Of America Inc |
以（－）－尼代地平（ｎｉｌｖａｄｉｐｉｎｅ）對映異構物減低類澱粉沉積、類澱粉神經毒性及微神經膠細胞增生之方法
|
|
SG178809A1
(en)
|
2007-10-05 |
2012-03-29 |
Genentech Inc |
Use of anti-amyloid beta antibody in ocular diseases
|
|
RS53174B
(sr)
|
2007-10-05 |
2014-06-30 |
Genentech Inc. |
Upotreba antiamiloidnog beta antitela u slučaju oboljenja oka
|
|
WO2009059239A2
(en)
*
|
2007-11-02 |
2009-05-07 |
Mayo Foundation For Medical Education And Research |
REDUCING Aβ42 LEVELS AND Aβ AGGREGATION
|
|
EP2149380A1
(en)
*
|
2008-07-29 |
2010-02-03 |
Medivet Pharma, S.L. |
Veterinary immunotherapy compositions for the Aged Related Cognitive Dysfunction.
|
|
US8846315B2
(en)
|
2008-08-12 |
2014-09-30 |
Zinfandel Pharmaceuticals, Inc. |
Disease risk factors and methods of use
|
|
WO2010042603A1
(en)
*
|
2008-10-08 |
2010-04-15 |
Cingulate Neuro Therapeutics, Llc |
Amyloid and depression
|
|
SI2408807T1
(sl)
|
2009-03-18 |
2021-11-30 |
Ac Immune Sa |
Postopek za terapevtsko uporabo
|
|
UA107571C2
(xx)
|
2009-04-03 |
2015-01-26 |
|
Фармацевтична композиція
|
|
JP5051274B2
(ja)
*
|
2009-06-04 |
2012-10-17 |
住友化学株式会社 |
加硫ゴムが有する粘弾性特性を改善させるためのｓ−（３−アミノプロピル）チオ硫酸および／またはその金属塩の使用
|
|
EP2311823A1
(en)
|
2009-10-15 |
2011-04-20 |
AC Immune S.A. |
2,6-Diaminopyridine compounds for treating diseases associated with amyloid proteins or for treating ocular diseases
|
|
ES2684475T3
(es)
|
2010-04-15 |
2018-10-03 |
Abbvie Inc. |
Proteínas que se unen a beta amiloide
|
|
PH12012502079A1
(en)
|
2010-04-16 |
2013-02-11 |
Ac Immune Sa |
Novel compounds for the treatment of diseases associated with amyloid or amyloid-like proteins
|
|
EP2377860A1
(en)
|
2010-04-16 |
2011-10-19 |
AC Immune S.A. |
Novel compounds for the treatment of diseases associated with amyloid or amyloid-like proteins
|
|
RU2607368C2
(ru)
|
2010-07-30 |
2017-01-10 |
Ац Иммуне С.А. |
Безопасные и функциональные гуманизированные антитела
|
|
CN103298833B
(zh)
|
2010-08-14 |
2015-12-16 |
Abbvie公司 |
β淀粉样蛋白结合蛋白
|
|
ES2548686T3
(es)
|
2010-10-07 |
2015-10-20 |
Ac Immune S.A. |
Anticuerpos que reconocen fosfo-Tau
|
|
AR083561A1
(es)
|
2010-10-26 |
2013-03-06 |
Ac Immune Sa |
Preparacion de una construccion antigenica
|
|
US20120321694A1
(en)
*
|
2010-10-27 |
2012-12-20 |
Daniel Larocque |
Compositions and uses
|
|
AU2012205798B2
(en)
|
2011-01-10 |
2016-02-25 |
Takeda Pharmaceutical Company Limited |
Methods and drug products for treating Alzheimer's disease
|
|
US9499488B2
(en)
*
|
2011-07-11 |
2016-11-22 |
Beth Israel Deaconess Medical Center, Inc. |
Vitamin D receptor agonists and uses thereof
|
|
KR102129220B1
(ko)
|
2011-09-23 |
2020-07-02 |
에이씨 이뮨 에스.에이. |
백신 요법
|
|
RU2639537C2
(ru)
|
2011-10-07 |
2017-12-21 |
Ац Иммуне С.А. |
Фосфоспецифичные антитела, распознающие тау
|
|
JP6293731B2
(ja)
|
2012-04-05 |
2018-03-14 |
エーシー イミューン エス．エー． |
ヒト化タウ抗体
|
|
US20130315891A1
(en)
|
2012-05-25 |
2013-11-28 |
Matthew Charles |
Formulations of human tissue kallikrein-1 for parenteral delivery and related methods
|
|
EP2854841B1
(en)
|
2012-06-04 |
2017-02-22 |
Diamedica Inc. |
Human tissue kallikrein 1 glycosylation isoforms
|
|
CA2881464C
(en)
*
|
2012-08-07 |
2021-12-21 |
Children's Medical Center Corporation |
Potassium channel openers for treating neurodegenerative diseases
|
|
GEP201706739B
(en)
*
|
2012-12-13 |
2017-09-25 |
H Lundbeck As |
Compositions comprising vortioxetine and donepezil
|
|
US9200068B2
(en)
*
|
2012-12-18 |
2015-12-01 |
Regents Of The University Of Minnesota |
Compositions and methods related to tauopathy
|
|
CN105143258B
(zh)
|
2013-03-15 |
2020-06-23 |
Ac免疫有限公司 |
抗Tau抗体和使用方法
|
|
WO2015110263A1
(en)
|
2014-01-21 |
2015-07-30 |
Ac Immune Sa |
Carbazole and carboline compounds for use in the diagnosis, treatment, alleviation or prevention of disorders associated with amyloid or amyolid-like proteins
|
|
US10314911B2
(en)
*
|
2014-04-08 |
2019-06-11 |
Healthpartners Research & Education |
Methods for protecting and treating traumatic brain injury, concussion and brain inflammation with intranasal insulin
|
|
AU2014393490B2
(en)
*
|
2014-05-09 |
2020-01-02 |
Tecnimede Sociedade Tecnico-Medicinal S.A. |
(S)-pirlindole or its pharmaceutically acceptable salts for use in medicine
|
|
MX368735B
(es)
*
|
2014-05-09 |
2019-10-14 |
Tecnimede Sociedade Tecnico Medicinal S |
(r)-pirlindol y sus sales farmaceuticamente aceptables para uso en medicina.
|
|
SI3221349T1
(sl)
|
2014-11-19 |
2021-02-26 |
Axon Neuroscience Se |
Humanizirano tau protitelo pri alzheimerjevi bolezni
|
|
EP4465050A3
(en)
|
2015-06-05 |
2025-06-11 |
Genentech, Inc. |
Anti-tau antibodies and methods of use
|
|
JP6928385B2
(ja)
|
2015-08-10 |
2021-09-01 |
アルジオン， インコーポレイテッド |
神経変性疾患を治療および予防するための組成物および方法
|
|
US10759837B2
(en)
|
2015-11-09 |
2020-09-01 |
The University Of British Columbia |
Anti-amyloid beta antibodies binding to a cyclic amyloid beta peptide
|
|
US10772969B2
(en)
|
2015-11-09 |
2020-09-15 |
The University Of British Columbia |
N-terminal epitopes in amyloid beta and conformationally-selective antibodies thereto
|
|
CA3004494A1
(en)
|
2015-11-09 |
2017-05-18 |
The University Of British Columiba |
Epitopes in amyloid beta mid-region and conformationally-selective antibodies thereto
|
|
ITUA20161679A1
(it)
|
2016-03-15 |
2017-09-15 |
Neuraxpharm Italy S P A |
Composizione per prevenire e trattare patologie neurodegenerative e disturbi cognitivi
|
|
CN109476729A
(zh)
|
2016-07-18 |
2019-03-15 |
英属哥伦比亚大学 |
淀粉样蛋白β的抗体
|
|
US11970521B2
(en)
|
2016-08-20 |
2024-04-30 |
Arizona Board Of Regents On Behalf Of The University Of Arizona |
Neuroprotective beta amyloid core peptides and peptidomimetic derivatives
|
|
US20180125920A1
(en)
|
2016-11-09 |
2018-05-10 |
The University Of British Columbia |
Methods for preventing and treating A-beta oligomer-associated and/or -induced diseases and conditions
|
|
MA48595A
(fr)
|
2016-12-07 |
2020-03-18 |
Ac Immune Sa |
Anticorps anti-tau et leurs méthodes d'utilisation
|
|
CN117820467A
(zh)
|
2016-12-07 |
2024-04-05 |
基因泰克公司 |
抗tau抗体和使用方法
|
|
CN110446501A
(zh)
|
2017-03-09 |
2019-11-12 |
代阿麦迪卡股份有限公司 |
组织激肽释放酶1的剂型
|
|
KR20190133162A
(ko)
|
2017-03-28 |
2019-12-02 |
제넨테크, 인크. |
신경퇴행성 질병의 치료 방법
|
|
WO2018200381A1
(en)
*
|
2017-04-25 |
2018-11-01 |
Temple Otorongo Llc |
Pharmaceutical composition comprising tryptophan and phyllokinin derivative for use in treating psychiatric and psychological conditions
|
|
KR101917128B1
(ko)
|
2017-04-28 |
2018-11-09 |
강원대학교산학협력단 |
산양삼 추출물을 포함하는 알츠하이머병의 예방 또는 치료용 약학 조성물
|
|
WO2019018445A1
(en)
*
|
2017-07-17 |
2019-01-24 |
Maxwell Biosciences, Inc. |
POLYTHERAPY MODULATING THE MODULATION OF CATHELICIDINE GENE EXPRESSION FOR THE TREATMENT OF ALZHEIMER'S DISEASE AND OTHER DISEASES
|
|
US12286469B2
(en)
|
2017-07-18 |
2025-04-29 |
The University Of British Columbia |
Humanized antibodies binding to amyloid-beta (A-beta)
|
|
WO2019074840A1
(en)
*
|
2017-10-09 |
2019-04-18 |
Keith Black |
COMPOSITIONS AND METHODS FOR TREATING ALZHEIMER'S DISEASE AND OTHER AMYLOID RELATED DISEASES
|
|
GB2571696B
(en)
|
2017-10-09 |
2020-05-27 |
Compass Pathways Ltd |
Large scale method for the preparation of Psilocybin and formulations of Psilocybin so produced
|
|
US12459965B2
(en)
|
2017-10-09 |
2025-11-04 |
Compass Pathfinder Limited |
Preparation of psilocybin, different polymorphic forms, intermediates, formulations and their use
|
|
KR102710762B1
(ko)
|
2017-10-25 |
2024-09-25 |
얀센 파마슈티칼즈, 인코포레이티드 |
인산화 타우 펩티드의 조성물 및 이의 용도
|
|
PE20211090A1
(es)
|
2018-01-05 |
2021-06-14 |
Ac Immune Sa |
Derivados de 1,3,4,5-tetrahidro-2h-pirido[4,3-b]indol para el tratamiento, alivio o prevencion de trastornos asociados con los agregados de tau
|
|
WO2019186276A2
(en)
|
2018-03-28 |
2019-10-03 |
Axon Neuroscience Se |
Antibody-based methods of detecting and treating alzheimer's disease
|
|
CN112313230B
(zh)
|
2018-06-04 |
2024-03-15 |
Ac免疫有限公司 |
用于治疗、缓解或预防与Tau聚集体相关的病症的新型化合物
|
|
EA202092557A1
(ru)
|
2018-06-04 |
2021-04-01 |
Ас Иммьюн Са |
СОЕДИНЕНИЯ ТЕТРАГИДРОБЕНЗОФУРО[2,3-c]ПИРИДИНА И БЕТА-КАРБОЛИНА ДЛЯ ЛЕЧЕНИЯ, ОБЛЕГЧЕНИЯ ИЛИ ПРОФИЛАКТИКИ РАССТРОЙСТВ, СВЯЗАННЫХ С АГРЕГАТАМИ ТАУ-БЕЛКА
|
|
KR20200086198A
(ko)
|
2019-01-08 |
2020-07-16 |
주식회사 솔고 바이오메디칼 |
수소 흡장 금속을 포함하는 치매 예방 또는 치료용 조성물
|
|
WO2020150423A1
(en)
*
|
2019-01-16 |
2020-07-23 |
Yumanity Therapeutics, Inc. |
Methods for the treatment of neurological disorders
|
|
AU2020219804A1
(en)
|
2019-02-08 |
2021-08-19 |
Ac Immune S.A. |
Method of safe administration of phosphorylated Tau peptide vaccine
|
|
JP7232931B2
(ja)
|
2019-03-01 |
2023-03-03 |
エイシー イミューン ソシエテ アノニム |
タウ凝集体に関連する障害の治療、緩和、または予防のための新規化合物
|
|
KR20220009954A
(ko)
|
2019-04-17 |
2022-01-25 |
컴퍼스 패쓰파인더 리미티드 |
신경인지 장애, 만성 통증을 치료하고 염증을 감소시키는 방법
|
|
JP7327788B2
(ja)
*
|
2019-08-06 |
2023-08-16 |
学校法人福岡大学 |
糖化産物生成抑制剤及び医薬組成物
|
|
WO2021055670A1
(en)
|
2019-09-20 |
2021-03-25 |
Avx Corporation |
Somatic cell-based electrical biosensor
|
|
WO2021067850A2
(en)
*
|
2019-10-02 |
2021-04-08 |
Washington University |
METHODS OF DETECTING circRNA
|
|
ES2821599A1
(es)
|
2019-10-24 |
2021-04-26 |
Univ Del Pais Vasco / Euskal Herriko Unibertsitatea |
Compuestos y metodos para el tratamiento de la enfermedad de alzheimer
|
|
CN112939823A
(zh)
*
|
2019-12-10 |
2021-06-11 |
中国石油天然气股份有限公司 |
泥页岩抑制剂制备方法及抑制剂的应用
|
|
KR20210133603A
(ko)
|
2020-04-29 |
2021-11-08 |
정지영 |
굼벵이를 포함하는 치매 예방 또는 치료용 조성물
|
|
US20210353566A1
(en)
*
|
2020-05-12 |
2021-11-18 |
Massachusetts Institute Of Technology |
The use of choline supplementation as therapy for apoe4-related disorders
|
|
AR123730A1
(es)
|
2020-10-15 |
2023-01-04 |
Ac Immune Sa |
Compuestos novedosos
|
|
JP7682515B2
(ja)
*
|
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|
|
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(ko)
*
|
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|
|
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(en)
|
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|
|
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(zh)
*
|
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|
|
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(en)
|
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|
|
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(ko)
*
|
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|
|
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(en)
|
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|
|
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(en)
|
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|
|
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(zh)
*
|
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|